Review: Systemic inflammation and A lzheimer's disease

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Type 2 diabetes as an inflammatory disease

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Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease

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High-mobility group box 1 protein (HMGB1): nuclear weapon in the immune arsenal

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Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease

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Biological basis of the behavior of sick animals

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Cytokine Storm in a Phase 1 Trial of the Anti-CD28 Monoclonal Antibody TGN1412

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Inflammaging and anti-inflammaging: a systemic perspective on aging and longevity emerged from studies in humans

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Local self-renewal can sustain CNS microglia maintenance and function throughout adult life

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Microglia in neurodegenerative disease

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Immunoregulatory Feedback Between Interleukin-1 and Glucocorticoid Hormones

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Long-term effects of Aβ42 immunisation in Alzheimer's disease: follow-up of a randomised, placebo-controlled phase I trial

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Cytokine-Associated Emotional and Cognitive Disturbances in Humans

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APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy

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Systemic inflammation and disease progression in Alzheimer disease

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Reversing established sepsis with antagonists of endogenous high-mobility group box 1

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A Meta-Analysis of Cytokines in Alzheimer's Disease

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Microglia in the adult brain arise from Ly-6ChiCCR2+ monocytes only under defined host conditions

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Etanercept and clinical outcomes, fatigue, and depression in psoriasis: double-blind placebo-controlled randomised phase III trial

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The Alzheimer's Disease-Associated Amyloid β-Protein Is an Antimicrobial Peptide

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In-vivo measurement of activated microglia in dementia

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Classification and prediction of clinical Alzheimer's diagnosis based on plasma signaling proteins

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Cytokine-induced sickness behaviour: mechanisms and implications

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Clinical trial of indomethacin in Alzheimer's disease

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Age, Neuropathology, and Dementia

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Blood–brain barrier: Ageing and microvascular disease – systematic review and meta-analysis

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Heterogeneity of Microglial Activation in the Innate Immune Response in the Brain

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Cytokine-induced sickness behavior: where do we stand?

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Regulation of innate immune responses in the brain

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Neurobehavioral Effects of Interferon-α in Cancer Patients Phenomenology and Paroxetine Responsiveness of Symptom Dimensions

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Early-onset autosomal dominant Alzheimer disease: prevalence, genetic heterogeneity, and mutation spectrum

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Neuro-inflammation induced by lipopolysaccharide causes cognitive impairment through enhancement of beta-amyloid generation

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Central and Systemic Endotoxin Challenges Exacerbate the Local Inflammatory Response and Increase Neuronal Death during Chronic Neurodegeneration

Cunningham, C., Wilcockson, D. C., Campion, S., Lunnon, K., & Perry, V. H. (2005) · The Journal of Neuroscience · doi:10.1523/jneurosci.2614-05.2005 · Cited by 768 · see citing works

Rates and risk factors for dementia and Alzheimer’s disease: Results from EURODEM pooled analyses

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Inflammation Causes Mood Changes Through Alterations in Subgenual Cingulate Activity and Mesolimbic Connectivity

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Lipopolysaccharide-Induced Inflammation Exacerbates Tau Pathology by a Cyclin-Dependent Kinase 5-Mediated Pathway in a Transgenic Model of Alzheimer's Disease

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TLR3: Interferon induction by double-stranded RNA including poly(I:C)☆

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Immune activation in brain aging and neurodegeneration: too much or too little?

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Cerebral Microglia Recruit Monocytes into the Brain in Response to Tumor Necrosis Factorα Signaling during Peripheral Organ Inflammation

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Blood brain barrier: ageing and microvascular disease-systematic review and meta-analysis

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Microglial activation by Alzheimer amyloid precursor protein and modulation by apolipoprotein E

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Genetic evidence implicates the immune system and cholesterol metabolism in the aetiology of Alzheimer’s disease

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When Two Strands Are Better Than One: The Mediators and Modulators of the Cellular Responses to Double-Stranded RNA

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Systemic inflammation induces acute behavioral and cognitive changes and accelerates neurodegenerative disease.

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Predictors of cognitive decline and mortality of aged people over a 10‐year period

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Convergence of atherosclerosis and Alzheimer's disease: inflammation, cholesterol, and misfolded proteins

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Elevated circulating tumor necrosis factor levels in Alzheimer's disease

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Microglia, amyloid, and cognition in Alzheimer's disease: An [11C](R)PK11195-PET and [11C]PIB-PET study

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Delirium accelerates cognitive decline in Alzheimer disease

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Alzheimer's disease: The amyloid cascade hypothesis: An update and reappraisal

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A randomized controlled trial of prednisone in Alzheimer’s disease

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A High Plasma Concentration of TNF- Is Associated With Dementia in Centenarians

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Randomized controlled trial of atorvastatin in mild to moderate Alzheimer disease: LEADe

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Cytokines and fever

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Neural and humoral pathways of communication from the immune system to the brain: parallel or convergent?

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Increased plasma levels of interleukin-1, interleukin-6 and α-1-antichymotrypsin in patients with Alzheimer's disease: peripheral inflammation or signals from the brain?

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Systemic immune challenges trigger and drive Alzheimer-like neuropathology in mice

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Atorvastatin for the treatment of mild to moderate Alzheimer disease: preliminary results.

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Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid β peptide in APPswe transgenic mice

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Cognitive Function Over Time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): Results of a Randomized, Controlled Trial of Naproxen and Celecoxib

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A randomized controlled trial of prednisone in Alzheimer’s disease

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Peripheral inflammation is associated with altered substantia nigra activity and psychomotor slowing in humans

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Tooth loss, dementia and neuropathology in the Nun Study

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Evidence for a Potent Antiinflammatory Effect of Rosiglitazone

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Coexpression of Microsomal-Type Prostaglandin E Synthase with Cyclooxygenase-2 in Brain Endothelial Cells of Rats during Endotoxin-Induced Fever

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Neuroprotective role of the innate immune system by microglia

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Activation of Vagal Afferents after Intravenous Injection of Interleukin-1β: Role of Endogenous Prostaglandins

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Microglial activation and amyloid deposition in mild cognitive impairment: A PET study

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Rosiglitazone Monotherapy in Mild-to-Moderate Alzheimer’s Disease: Results from a Randomized, Double-Blind, Placebo-Controlled Phase III Study

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Interleukin-1β in Immune Cells of the Abdominal Vagus Nerve: a Link between the Immune and Nervous Systems?

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The Neuropathology of Septic Shock

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Pathway across the blood–brain barrier

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Neural Origins of Human Sickness in Interoceptive Responses to Inflammation

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Extended results of the Alzheimer's disease anti‐inflammatory prevention trial

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