Systemic Regulators of Skeletal Muscle Regeneration in Obesity

PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes

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Global Burden of Diabetes, 1995–2025: Prevalence, numerical estimates, and projections

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SATELLITE CELL OF SKELETAL MUSCLE FIBERS

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Akt/mTOR pathway is a crucial regulator of skeletal muscle hypertrophy and can prevent muscle atrophy in vivo

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Dysfunction of Mitochondria in Human Skeletal Muscle in Type 2 Diabetes

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Mechanisms for Insulin Resistance: Common Threads and Missing Links

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Obesity and nonalcoholic fatty liver disease: biochemical, metabolic, and clinical implications

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Muscle injury activates resident fibro/adipogenic progenitors that facilitate myogenesis

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Exercise, GLUT4, and skeletal muscle glucose uptake

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IKKβ/NF-κB Activation Causes Severe Muscle Wasting in Mice

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Mesenchymal progenitors distinct from satellite cells contribute to ectopic fat cell formation in skeletal muscle

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Ectopic Fat in Insulin Resistance, Dyslipidemia, and Cardiometabolic Disease

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Regulation of Muscle Fiber Type and Running Endurance by PPARδ

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PGC-1α Deficiency Causes Multi-System Energy Metabolic Derangements: Muscle Dysfunction, Abnormal Weight Control and Hepatic Steatosis

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Obesity and Free Fatty Acids

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Mitochondrial dysfunction results from oxidative stress in the skeletal muscle of diet-induced insulin-resistant mice

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Type 2 Innate Signals Stimulate Fibro/Adipogenic Progenitors to Facilitate Muscle Regeneration

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Interleukin‐6 myokine signaling in skeletal muscle: a double‐edged sword?

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Accelerated Loss of Skeletal Muscle Strength in Older Adults With Type 2 Diabetes

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The Mitochondrial-Derived Peptide MOTS-c Promotes Metabolic Homeostasis and Reduces Obesity and Insulin Resistance

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Thigh adipose tissue distribution is associated with insulin resistance in obesity and in type 2 diabetes mellitus

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Release of Interleukins and Other Inflammatory Cytokines by Human Adipose Tissue Is Enhanced in Obesity and Primarily due to the Nonfat Cells

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Lipid oxidation is reduced in obese human skeletal muscle

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Sarcopenia Exacerbates Obesity-Associated Insulin Resistance and Dysglycemia: Findings from the National Health and Nutrition Examination Survey III

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Non-alcoholic fatty liver disease and obesity: Biochemical, metabolic and clinical presentations

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Prevalence and Determinant Factors of Sarcopenia in Patients With Type 2 Diabetes

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The NAD+-Dependent SIRT1 Deacetylase Translates a Metabolic Switch into Regulatory Epigenetics in Skeletal Muscle Stem Cells

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Interleukin-6 and Diabetes

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Peroxisome proliferator‐activated receptor δ controls muscle development and oxydative capability

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Suppression of body fat accumulation in myostatin-deficient mice

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Highly Efficient, Functional Engraftment of Skeletal Muscle Stem Cells in Dystrophic Muscles

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Sirtuin-3 (Sirt3) regulates skeletal muscle metabolism and insulin signaling via altered mitochondrial oxidation and reactive oxygen species production

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AMP-activated protein kinase regulates GLUT4 transcription by phosphorylating histone deacetylase 5

McGee, S. L., van Denderen, B. J. W., Howlett, K. F., Mollica, J., Schertzer, J. D., Kemp, B. E., & Hargreaves, M. (2008) · Diabetes · doi:10.2337/db07-0843 · Cited by 455 · see citing works

Interleukin 6 receptor antibody inhibits muscle atrophy and modulates proteolytic systems in interleukin 6 transgenic mice.

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Impact of Oxidative Stress on Exercising Skeletal Muscle

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Fast/Glycolytic Muscle Fiber Growth Reduces Fat Mass and Improves Metabolic Parameters in Obese Mice

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Relationship Between Sarcopenia and Nonalcoholic Fatty Liver Disease: The Korean Sarcopenic Obesity Study

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TNF-α regulates myogenesis and muscle regeneration by activating p38 MAPK

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Mechanisms underlying skeletal muscle insulin resistance induced by fatty acids: importance of the mitochondrial function

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Release of Hepatocyte Growth Factor from Mechanically Stretched Skeletal Muscle Satellite Cells and Role of pH and Nitric Oxide

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Macrophage Polarization in Obesity and Type 2 Diabetes: Weighing Down Our Understanding of Macrophage Function?

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Histone deacetylase (HDAC) inhibition as a novel treatment for diabetes mellitus

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The effects of obesity on skeletal muscle regeneration

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Inhibition of Class I Histone Deacetylases Unveils a Mitochondrial Signature and Enhances Oxidative Metabolism in Skeletal Muscle and Adipose Tissue

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Role of TGF-β signaling in inherited and acquired myopathies

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Myostatin modulates adipogenesis to generate adipocytes with favorable metabolic effects

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Intramyocellular Lipid Content in Human Skeletal Muscle

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Intermuscular and perimuscular fat expansion in obesity correlates with skeletal muscle T cell and macrophage infiltration and insulin resistance

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MOTS-c: a novel mitochondrial-derived peptide regulating muscle and fat metabolism

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By the numbers: New estimates from the IDF Diabetes Atlas Update for 2012

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Interactions between muscle stem cells, mesenchymal-derived cells and immune cells in muscle homeostasis, regeneration and disease

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Obesity Impairs Skeletal Muscle Regeneration Through Inhibition of AMPK

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Smad3 Deficiency in Mice Protects Against Insulin Resistance and Obesity Induced by a High-Fat Diet

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Baf60c drives glycolytic metabolism in the muscle and improves systemic glucose homeostasis through Deptor-mediated Akt activation

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Sarcopenia and cachexia: the adaptations of negative regulators of skeletal muscle mass

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IGF-I/PI3K/Akt and IGF-I/MAPK/ERK pathways in vivo in skeletal muscle are regulated by nutrition and contribute to somatic growth in the fine flounder

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PTEN Inhibition Improves Muscle Regeneration in Mice Fed a High-Fat Diet

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Exercise ameliorates chronic kidney disease–induced defects in muscle protein metabolism and progenitor cell function

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Human Satellite Cell-Proliferation in Vitro Is Regulated by Autocrine Secretion of IL-6 Stimulated by a Soluble Factor(s) Released by Activated Monocytes

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Skeletal Muscle Stem Cells: Effects of Aging and Metabolism on Muscle Regenerative FunctionPreprint

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Follistatin Improves Skeletal Muscle Healing after Injury and Disease through an Interaction with Muscle Regeneration, Angiogenesis, and Fibrosis

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Early Life Nutrition Modulates Muscle Stem Cell Number: Implications for Muscle Mass and Repair

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Can muscle regeneration fail in chronic inflammation: a weakness in inflammatory myopathies?

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The PGE2 EP3 Receptor Regulates Diet-Induced Adiposity in Male Mice

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Transforming Growth Factor-β–Induced Inhibition of Myogenesis Is Mediated Through Smad Pathway and Is Modulated by Microtubule Dynamic Stability

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Improving Insulin Sensitivity With HDAC Inhibitor

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Diet‐induced obesity alters anabolic signalling in mice at the onset of skeletal muscle regeneration

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Satellite Cells Derived from Obese Humans with Type 2 Diabetes and Differentiated into Myocytes In Vitro Exhibit Abnormal Response to IL-6

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Muscle insulin resistance: a case of fat overconsumption, not mitochondrial dysfunction

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Diet-induced obesity impairs muscle satellite cell activation and muscle repair through alterations in hepatocyte growth factor signaling

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A Mitochondrially Encoded Hormone Ameliorates Obesity and Insulin Resistance

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Targeted Expression of Catalase to Mitochondria Protects Against Ischemic Myopathy in High-Fat Diet–Fed Mice

RYAN, T. E., Schmidt, C. A., Green, T. D., Spangenburg, E. E., Neufer, P. D., & McClung, J. M. (2016) · Diabetes · doi:10.2337/db16-0387 · Cited by 55 · see citing works

The Baf60c/Deptor Pathway Links Skeletal Muscle Inflammation to Glucose Homeostasis in Obesity

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Histone Deacetylase Inhibitors: a Potential Epigenetic Treatment for Duchenne Muscular Dystrophy

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Early skeletal muscle adaptations to short‐term high‐fat diet in humans before changes in insulin sensitivity

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Diacylglycerol kinase-δ regulates AMPK signaling, lipid metabolism, and skeletal muscle energetics

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Grb10 Deletion Enhances Muscle Cell Proliferation, Differentiation and GLUT4 Plasma Membrane Translocation

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Activation of adipose tissue macrophages in obese mice does not require lymphocytes

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Obesity-Induced Insulin Resistance in Human Skeletal Muscle Is Characterised by Defective Activation of p42/p44 MAP Kinase

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Phospho-tyrosine phosphatase inhibitor Bpv(Hopic) enhances C2C12 myoblast migration in vitro. Requirement of PI3K/AKT and MAPK/ERK pathways

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Impaired skeletal muscle regeneration in diabetes: From cellular and molecular mechanisms to novel treatments

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High Fat With High Sucrose Diet Leads to Obesity and Induces Myodegeneration

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Multifaceted Interweaving Between Extracellular Matrix, Insulin Resistance, and Skeletal Muscle

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The Role of Omega-3 Polyunsaturated Fatty Acids and Their Lipid Mediators on Skeletal Muscle Regeneration: A Narrative Review

Jannas-Vela, S., Espinosa, A., Candia, A. A., Flores-Opazo, M., Peñailillo, L. E., & Valenzuela, R. (2023) · Nutrients · doi:10.3390/nu15040871 · Cited by 56 · see citing works

Crossroads between peripheral atherosclerosis, western-type diet and skeletal muscle pathophysiology: emphasis on apolipoprotein E deficiency and peripheral arterial disease

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Overweight in the Elderly Induces a Switch in Energy Metabolism that Undermines Muscle Integrity

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