Student or educator? Sign up with your school email and get 6 months of Pro free.
CoChat
Sign Up
Cited by 1,726

The DOI matches its Crossref record; 28 of the 28 references it cites were found in a registry or an index.

Bifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut

Open access
Rivière, Audrey, Selak, Marija, Lantin, David, Leroy, Frédéric, De Vuyst, Luc·2016·Frontiers in Microbiology
DOI 10.3389/fmicb.2016.00979
Open this paper in CoChat — free account

Abstract

With the increasing amount of evidence linking certain disorders of the human body to a disturbed gut microbiota, there is a growing interest for compounds that positively influence its composition and activity through diet. Besides the consumption of probiotics to stimulate favorable bacterial communities in the human gastrointestinal tract, prebiotics such as inulin-type fructans (ITF) and arabinoxylan-oligosaccharides (AXOS) can be consumed to increase the number of bifidobacteria in the colon. Several functions have been attributed to bifidobacteria, encompassing degradation of non-digestible carbohydrates, protection against pathogens, production of vitamin B, antioxidants, and conjugated linoleic acids, and stimulation of the immune system. During life, the numbers of bifidobacteria decrease from up to 90% of the total colon microbiota in vaginally delivered breast-fed infants to <5% in the colon of adults and they decrease even more in that of elderly as well as in patients with certain disorders such as antibiotic-associated diarrhea, inflammatory bowel disease, irritable bowel syndrome, obesity, allergies, and regressive autism. It has been suggested that the bifidogenic effects of ITF and AXOS are the result of strain-specific yet complementary carbohydrate degradation mechanisms within cooperating bifidobacterial consortia. Except for a bifidogenic effect, ITF and AXOS also have shown to cause a butyrogenic effect in the human colon, i.e., an enhancement of colon butyrate production. Butyrate is an essential metabolite in the human colon, as it is the preferred energy source for the colon epithelial cells, contributes to the maintenance of the gut barrier functions, and has immunomodulatory and anti-inflammatory properties. It has been shown that the butyrogenic effects of ITF and AXOS are the result of cross-feeding interactions between bifidobacteria and butyrate-producing colon bacteria, such as Faecalibacterium prausnitzii (clostridial cluster IV) and Anaerostipes, Eubacterium, and Roseburia species (clostridial cluster XIVa). These kinds of interactions possibly favor the co-existence of bifidobacterial strains with other bifidobacteria and with butyrate-producing colon bacteria in the human colon.

Overview

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Integrity signals

Registry

Crossref · 10.3389/fmicb.2016.00979

Cites

28 of 28 references verified0 citation errors · 0 not checkable

Statistics

Verification

Claims the paper makes

The claims and statistics of this paper haven’t been checked yet.

Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.

A few free checks a day · papers already verified open instantly · results are public

Self-check

Percentages, sums and reported differences re-computed from the paper’s own numbers.

The self-check needs the paper’s full text.

Citations

Cites

Show all 28 references

Research works printed but not linked: 161

  1. Al-Lahham, 2010, Biological effects of propionic acid in humans; metabolism, potential applications and underlying mechanisms, Biochim. Biophys. Acta, 1801, 1175, 10.1016/j.bbalip.2010.07.007 · DOI · Paper page
  2. Antoine, 2003, Individual contribution of grain outer layers and their cell wall structure to the mechanical properties of wheat bran, J. Agric. Food Chem., 51, 2026, 10.1021/jf0261598 · DOI · Paper page
  3. Aroniadis, 2014, Intestinal microbiota and the efficacy of fecal microbiota transplantation in gastrointestinal disease, Gastroenterol. Hepatol., 10, 230
  4. Arumugam, 2011, Enterotypes of the human gut microbiome, Nature, 473, 174, 10.1038/nature09944 · DOI · Paper page
  5. Barron, 2007, Relative amounts of tissues in mature wheat (Triticum aestivum L.) grain and their carbohydrate and phenolic acid composition, J. Cereal Sci., 45, 88, 10.1016/j.jcs.2006.07.004 · DOI · Paper page
  6. Belenguer, 2011, Rates of production and utilization of lactate by microbial communities from the human colon, FEMS Microbiol. Ecol., 77, 107, 10.1111/j.1574-6941.2011.01086.x · DOI
  7. Benamrouche, 2002, A chemical and histological study on the effect of (1 → 4)-β-endo-xylanase treatment on wheat bran, J. Cereal Sci., 36, 253, 10.1006/jcrs.2001.0427 · DOI
  8. Bindels, 2015, Towards a more comprehensive concept for prebiotics, Nat. Rev. Gastroenterol. Hepatol., 12, 303, 10.1038/nrgastro.2015.47 · DOI · Paper page
  9. Boets, 2013, In vivo evaluation of bacterial cross-feeding in the colon using stable isotope techniques: a pilot study, 10.1016/S0016-5085(13)62082-X · DOI
  10. Bottacini, 2014, Diversity, ecology and intestinal function of bifidobacteria, Microb. Cell Fact., 13, S4, 10.1186/1475-2859-13-S1-S4 · DOI
  11. Braniste, 2014, The gut microbiota influences blood-brain barrier permeability in mice, Sci. Transl. Med., 6, 263r, 10.1126/scitranslmed.3009759 · DOI · Paper page
  12. Broekaert, 2009, (Arabino)xylan Oligosaccharide Preparation
  13. Broekaert, 2011, Prebiotic and other health-related effects of cereal-derived arabinoxylans, arabinoxylan-oligosaccharides, and xylooligosaccharides, Crit. Rev. Food Sci. Nutr., 51, 178, 10.1080/10408390903044768 · DOI
  14. Bunzel, 2001, Diferulates as structural components in soluble and insoluble cereal dietary fibre, J. Sci. Food Agric., 81, 653, 10.1002/jsfa.861 · DOI
  15. Cani, 2015, Novel opportunities for next-generation probiotics targeting metabolic syndrome, Curr. Opin. Biotechnol., 32, 21, 10.1016/j.copbio.2014.10.006 · DOI · Paper page
  16. Chassard, 2007, Characterization of the xylan-degrading microbial community from human faeces, FEMS Microbiol. Ecol., 61, 121, 10.1111/j.1574-6941.2007.00314.x · DOI
  17. Choi, 2014, Bifidobacterium faecale sp. nov., isolated from human >faeces, Int. J. Syst. Evol. Microbiol., 64, 3134, 10.1099/ijs.0.063479-0 · DOI
  18. Cloetens, 2010, Tolerance of arabinoxylan-oligosaccharides and their prebiotic activity in healthy subjects: a randomised, placebo-controlled cross-over study, Br. J. Nutr., 103, 703, 10.1017/S0007114509992248 · DOI
  19. Courtin, 2009, Occurrence of arabinoxylo-oligosaccharides and arabinogalactan peptides in beer, J. Am. Soc. Brew. Chem., 67, 112, 10.1094/asbcj-2009-0323-01 · DOI
  20. Crittenden, 2002, In vitro fermentation of cereal dietary fibre carbohydrates by probiotic and intestinal bacteria, J. Sci. Food Agric., 82, 781, 10.1002/jsfa.1095 · DOI
  21. Cui, 2016, Step-up fecal microbiota transplantation (FMT) strategy, Gut Microbes., 10.1080/19490976.2016.1151608 · DOI
  22. Damen, 2011, Prebiotic effects and intestinal fermentation of cereal arabinoxylans and arabinoxylan oligosaccharides in rats depend strongly on their structural properties and joint presence, Mol. Nutr. Food. Res., 55, 1862, 10.1002/mnfr.201100377 · DOI
  23. Delgado, 2013, Microbiological survey of the human gastric ecosystem using culturing and pyrosequencing methods, Microb. Ecol., 63, 763, 10.1007/s00248-013-0192-5 · DOI
  24. de Vos, 2013, Fame and future of faecal transplantations - developing next-generation therapies with synthetic microbiomes, Microb. Biotechnol., 6, 316, 10.1111/1751-7915.12047 · DOI
  25. de Vos, 2012, Role of the intestinal microbiome in health and disease: from correlation to causation, Nutr. Rev., 1, S45, 10.1111/j.1753-4887.2012.00505.x · DOI · Paper page
  26. De Vuyst, 2011, Cross-feeding between bifidobacteria and butyrate-producing colon bacteria explains bifidobacterial competitiveness, butyrate production, and gas production, Int. J. Food Microbiol., 149, 73, 10.1016/j.ijfoodmicro.2011.03.003 · DOI · Paper page
  27. De Vuyst, 2014, Summer meeting 2013: growth and physiology of bifidobacteria, J. Appl. Microbiol., 116, 477, 10.1111/jam.12415 · DOI
  28. Di Gioia, 2014, Bifidobacteria: their impact on gut microbiota composition and their applications as probiotics in infants, Appl. Microbiol. Biotechnol., 98, 563, 10.1007/s00253-013-5405-9 · DOI
  29. Dinan, 2015, Collective unconscious: how gut microbes shape human behavior, J. Psychiat. Res., 63, 1, 10.1016/j.jpsychires.2015.02.021 · DOI · Paper page
  30. Dodd, 2009, Enzymatic deconstruction of xylan for biofuel production, Glob. Change Biol. Bioenergy, 18, 2, 10.1111/j.1757-1707.2009.01004.x · DOI · Paper page
  31. Dodd, 2011, Xylan degradation, a metabolic property shared by rumen and human colonic Bacteroidetes, Mol. Microbiol., 79, 292, 10.1111/j.1365-2958.2010.07473.x · DOI · Paper page
  32. Duncan, 2013, Probiotics and prebiotics and health in ageing populations, Maturitas, 75, 44, 10.1016/j.maturitas.2013.02.004 · DOI
  33. Duncan, 2004, Lactate-utilizing bacteria, isolated from human feces, that produce butyrate as a major fermentation product, Appl. Environ. Microbiol., 70, 5810, 10.1128/AEM.70.10.5810-5817.2004 · DOI
  34. Duncan, 2009, The role of pH in determining the species composition of the human colonic microbiota, Environ. Microbiol., 11, 2112, 10.1111/j.1462-2920.2009.01931.x · DOI · Paper page
  35. Eeckhaut, 2014, Progress towards butyrate-producing pharmabiotics: Butyricicoccus pullicaecorum capsule and efficacy in TNBS models in comparison with therapeutics, Gut, 63, 367, 10.1136/gutjnl-2013-305293 · DOI
  36. Eeckhaut, 2013, Butyricicoccus pullicaecorum in inflammatory bowel disease, Gut, 62, 1745, 10.1136/gutjnl-2012-303611 · DOI
  37. EFSA, 2010, Scientific opinion on the substantiation of health claims related to live yoghurt cultures and improved lactose digestion (ID 1143, 2976), pursuant to Article 13 (1) of regulation (EC) No 1924/20061, EFSA J., 8, 1763, 10.2903/j.efsa.2010.1763 · DOI
  38. EFSA, 2011a, Scientific opinion on the substantiation of health claims related to resistant starch and reduction of post-prandial glycaemic responses (ID 681), “digestive health benefits” (ID 682) and “favours a normal colon metabolism” (ID 783) pursuant to Article 13 (1) of Regulation (EC) No 1924/2006, EFSA J., 9, 2024, 10.2903/j.efsa.2011.2024 · DOI
  39. EFSA, 2011b, Scientific opinion on the substantiation of health claims related to arabinoxylan produced from wheat endosperm and reduction of post-prandial glycaemic responses (ID 830) pursuant to Article 13 (1) of Regulation (EC) No 1924/2006, EFSA J., 9, 2205, 10.2903/j.efsa.2011.2205 · DOI
  40. EFSA, 2015, Scientific opinion on the substantiation of a health claim related to “native chicory inulin” and maintenance of normal defecation by increasing stool frequency pursuant to Article 13.5 of Regulation (EC) No 1924/2006, EFSA J., 13, 3951, 10.2903/j.efsa.2015.3951 · DOI
  41. Egan, 2014, Cross-feeding by Bifidobacterium breve UCC2003 during co-cultivation with Bifidobacterium bifidum PRL2010 in a mucin-based medium, BMC Microbiol., 14, 282, 10.1186/s12866-014-0282-7 · DOI
  42. Ehrmann, 2003, Identification of the gene for beta-fructofuranosidase of Bifidobacterium lactis DSM10140T and characterization of the enzyme expressed in Escherichia coli, Curr. Microbiol., 46, 391, 10.1007/s00284-002-3908-1 · DOI
  43. El Aidy, 2013, Intestinal colonization: how key microbial players become established in this dynamic process, Bioessays, 35, 913, 10.1002/bies.201300073 · DOI
  44. European Commission, 2008, Commission directive 2008/100/EC
  45. Euzéby, 1997, List of bacterial names with standing in nomenclature: a folder available on the internet, Int. J. Syst. Bacteriol., 47, 590, 10.1099/00207713-47-2-590 · DOI · Paper page
  46. Euzéby, 2016, Bifidobacterium, List of Prokaryotic Names with Standing in Nomenclature.
  47. Everard, 2013, Diabetes, obesity and gut microbiota, Best Pract. Res. Clin. Gastroenterol., 27, 73, 10.1016/j.bpg.2013.03.007 · DOI · Paper page
  48. Everard, 2011, Responses of gut microbiota and glucose and lipid metabolism to prebiotics in genetic obese and diet-induced leptin-resistant mice, Diabetes, 60, 2775, 10.2337/db11-0227 · DOI · Paper page
  49. Falony, 2009a, Coculture fermentations of Bifidobacterium species and Bacteroides thetaiotaomicron reveal a mechanistic insight into the prebiotic effect of inulin-type fructans, Appl. Environ. Microbiol., 75, 2312, 10.1128/AEM.02649-08 · DOI
  50. Falony, 2009b, In vitro kinetic analysis of fermentation of prebiotic inulin-type fructans by Bifidobacterium species reveals four different phenotypes, Appl. Environ. Microbiol., 75, 454, 10.1128/AEM.01488-08 · DOI
  51. Falony, 2009c, In vitro kinetics of prebiotic inulin-type fructan fermentation by butyrate-producing colon bacteria: implementation of online gas chromatography for quantitative analysis of carbon dioxide and hydrogen gas production, Appl. Environ. Microbiol., 75, 5884, 10.1128/AEM.00876-09 · DOI
  52. Falony, 2006, Cross-feeding between Bifidobacterium longum BB536 and acetate-converting, butyrate-producing colon bacteria during growth on oligofructose, Appl. Environ. Microbiol., 72, 7835, 10.1128/AEM.01296-06 · DOI
  53. Figueroa-González, 2011, Probiotics and prebiotics - perspectives and challenges, J. Sci. Food Agric., 91, 1341, 10.1002/jsfa.4367 · DOI
  54. Gagnon, 2015, Bioaccessible antioxidants in milk fermented by Bifidobacterium longum subsp. longum strains, Biomed. Res. Int., 2015, 169381, 10.1155/2015/169381 · DOI
  55. Geirnaert, 2014, Butyricicoccus pullicaecorum, a butyrate producer with probiotic potential, is intrinsically tolerant to stomach and small intestine conditions, Anaerobe, 30, 70, 10.1016/j.anaerobe.2014.08.010 · DOI
  56. Gevers, 2014, The treatment-naive microbiome in new-onset Crohn's disease, Cell Host Microbe, 15, 382, 10.1016/j.chom.2014.02.005 · DOI · Paper page
  57. Gibson, 2004, Dietary modulation of the human colonic microbiota: updating the concept of prebiotics, Nutr. Res. Rev., 17, 259, 10.1079/NRR200479 · DOI
  58. Gibson, 2010, Dietary prebiotics: current status and new definition, Food Sci. Technol. Bull., 7, 1, 10.1616/1476-2137.15880 · DOI
  59. Glanville, 2015, A review of the systematic review process and its applicability for use in evaluating evidence for health claims on probiotic foods in the European Union, Nutr. J., 14, 16, 10.1186/s12937-015-0004-5 · DOI
  60. Gorissen, 2012, Conjugated linoleic and linolenic acid production kinetics by bifidobacteria differ among strains, Int. J. Food Microbiol., 155, 234, 10.1016/j.ijfoodmicro.2012.02.012 · DOI
  61. Gorissen, 2010, Production of conjugated linoleic acid and conjugated linolenic acid isomers by Bifidobacterium species, Appl. Microbiol. Biotechnol., 87, 2257, 10.1007/s00253-010-2713-1 · DOI
  62. Gosálbez, 2015, Probiotics in transition: novel strategies, Trends Biotechnol., 33, 195, 10.1016/j.tibtech.2015.01.006 · DOI
  63. Gråsten, 2003, Effects of wheat pentosan and inulin on the metabolic activity of fecal microbiota and on bowel function in healthy humans, Nutr. Res., 23, 1503, 10.1016/S0271-5317(03)00164-7 · DOI
  64. Grimm, 2014, Bifidobacteria-host interactions - an update on colonisation factors, Biomed. Res. Int., 2014, 960826, 10.1155/2014/960826 · DOI
  65. Grootaert, 2007, Microbial metabolism and prebiotic potency of arabinoxylan oligosaccharides in the human intestine, Trends Food Sci. Technol., 18, 64, 10.1016/j.tifs.2006.08.004 · DOI
  66. Grootaert, 2009, Comparison of prebiotic effects of arabinoxylan oligosaccharides and inulin in a simulator of the human intestinal microbial ecosystem, FEMS Microbiol. Ecol., 69, 231, 10.1111/j.1574-6941.2009.00712.x · DOI
  67. Gruppen, 1993, Enzymic degradation of water-unextractable cell wall material and arabinoxylans from wheat flour, J. Cereal Sci., 18, 129, 10.1006/jcrs.1993.1041 · DOI
  68. Havenaar, 2011, Intestinal health functions of colonic microbial metabolites: a review, Benef. Microbes, 2, 103, 10.3920/BM2011.0003 · DOI
  69. Hill, 2014, Expert consensus document. The International Scientific Association for Probiotics and Prebiotics consensus statement on the scope and appropriate use of the term probiotic, Nat. Rev. Gastroenterol. Hepatol., 11, 506, 10.1038/nrgastro.2014.66 · DOI
  70. Hood, 2012, Tackling the microbiome, Science, 336, 1209, 10.1126/science.1225475 · DOI
  71. Hopkins, 2003, Degradation of cross-linked and non-cross-linked arabinoxylans by the intestinal microbiota in children, Appl. Environ. Microbiol., 69, 6354, 10.1128/AEM.69.11.6354-6360.2003 · DOI
  72. Hutkins, 2016, Prebiotics: why definitions matter, Curr. Opin. Biotechnol., 37, 1, 10.1016/j.copbio.2015.09.001 · DOI · Paper page
  73. Ishikawa, 2013, Ethnic diversity of gut microbiota: species characterization of Bacteroides fragilis group and genus Bifidobacterium in healthy Belgian adults, and comparison with data from Japanese subjects, J. Biosci. Bioeng., 116, 265, 10.1016/j.jbiosc.2013.02.010 · DOI
  74. Izydorczyk, 1995, Cereal arabinoxylans: advances in structure and physicochemical properties, Carbohydr. Polym., 28, 33, 10.1016/0144-8617(95)00077-1 · DOI · Paper page
  75. Izydorczyk, 2006, Arabinoxylans: technology and nutritionally functional plant polysaccharides, 249, 10.1201/9781420003512.ch7 · DOI
  76. Jedrzejczak-Krzepkowska, 2011, Biosynthesis, purification and characterization of β-fructofuranosidase from Bifidobacterium longum KN29.1, Proc. Biochem., 46, 1963, 10.1016/j.procbio.2011.07.005 · DOI
  77. Kapel, 2014, Practical implementation of faecal transplantation, Clin. Microbiol. Infec., 20, 1098, 10.1111/1469-0691.12796 · DOI
  78. Khodayar-Pardo, 2014, Impact of lactation stage, gestational age and mode of delivery on breast milk microbiota, J. Perinatol., 34, 599, 10.1038/jp.2014.47 · DOI · Paper page
  79. Klijn, 2005, Lessons from the genomes of bifidobacteria, FEMS Microbiol. Rev., 29, 491, 10.1016/j.fmrre.2005.04.010 · DOI
  80. Kumar, 2015, Novel probiotics and prebiotics: road to the market, Curr. Opin. Biotechnol., 32, 99, 10.1016/j.copbio.2014.11.021 · DOI
  81. Lagaert, 2014, β-Xylosidases and α-L-arabinofuranosidases: accessory enzymes for arabinoxylan degradation, Biotechnol. Adv., 32, 316, 10.1016/j.biotechadv.2013.11.005 · DOI
  82. Lagaert, 2010, Substrate specificity of three recombinant α-L-arabinofuranosidases from Bifidobacterium adolescentis and their divergent action on arabinoxylan and arabinoxylan oligosaccharides, Biochem. Biophys. Res. Commun., 26, 644, 10.1016/j.bbrc.2010.10.075 · DOI
  83. Lagaert, 2011, Characterization of two β-xylosidases from Bifidobacterium adolescentis and their contribution to the hydrolysis of prebiotic xylooligosaccharides, Appl. Microbiol. Biotechnol., 92, 1179, 10.1007/s00253-011-3396-y · DOI
  84. Laureys, 2016, Bifidobacterium aquikefiri sp. nov., isolated from water kefir, Int. J. Syst. Evolut. Microbiol., 66, 1281, 10.1099/ijsem.0.000877 · DOI
  85. Laureys, 2014, Microbial species diversity, community dynamics, and metabolite kinetics of water kefir fermentation, Appl. Environ. Microbiol., 80, 2564, 10.1128/AEM.03978-13 · DOI
  86. Leahy, 2005, Getting better with bifidobacteria, J. Appl. Microbiol., 98, 1303, 10.1111/j.1365-2672.2005.02600.x · DOI
  87. Li, 2016, Durable coexistence of donor and recipient strains after fecal microbiota transplantation, Science, 352, 586, 10.1126/science.aad8852 · DOI
  88. Lombard, 2014, The carbohydrate-active enzymes database (CAZy) in 2013, Nucleic Acids Res., 42, D490, 10.1093/nar/gkt1178 · DOI
  89. Louis, 2009, Diversity, metabolism and microbial ecology of butyrate-producing bacteria from the human large intestine, FEMS Microbiol. Lett., 294, 1, 10.1111/j.1574-6968.2009.01514.x · DOI · Paper page
  90. Louis, 2014, The gut microbiota, bacterial metabolites and colorectal cancer, Nat. Rev. Microbiol., 12, 661, 10.1038/nrmicro3344 · DOI
  91. Macfarlane, 2008, Bacterial metabolism and health-related effects of galacto-oligosaccharides and other prebiotics, J. Appl. Microbiol., 104, 305, 10.1111/j.1365-2672.2007.03520.x · DOI · Paper page
  92. Maes, 2002, Structural characterisation of water-extractable and water-unextractable arabinoxylans in wheat bran, J. Cereal Sci., 35, 315, 10.1006/jcrs.2001.0439 · DOI
  93. Mahowald, 2009, Characterizing a model human gut microbiota composed of members of its two dominant bacterial phyla, Proc. Natl. Acad. Sci. U.S.A., 106, 5859, 10.1073/pnas.0901529106 · DOI · Paper page
  94. Maki, 2012, Digestive and physiologic effects of a wheat bran extract, arabino-xylan-oligosaccharide, in breakfast cereal, Nutrition, 28, 1115, 10.1016/j.nut.2012.02.010 · DOI
  95. Marchesi, 2007, Rapid and noninvasive metabonomic characterization of inflammatory bowel disease, J. Proteome Res., 6, 546, 10.1021/pr060470d · DOI · Paper page
  96. Marteau, 2013, Butyrate-producing bacteria as pharmabiotics for inflammatory bowel disease, Gut, 62, 1673, 10.1136/gutjnl-2012-304240 · DOI
  97. McLaughlin, 2015, Carbohydrate catabolic diversity of bifidobacteria and lactobacilli of human origin, Int. J. Food Microbiol., 203, 109, 10.1016/j.ijfoodmicro.2015.03.008 · DOI
  98. Mendis, 2013, Arabinoxylans and human health, Food Hydrocoll., 42, 239, 10.1016/j.foodhyd.2013.07.022 · DOI
  99. Miquel, 2014, Ecology and metabolism of the beneficial intestinal commensal bacterium Faecalibacterium prausnitzii, Gut Microbes, 5, 146, 10.4161/gmic.27651 · DOI
  100. Moens, 2016, Bifidobacterial inulin-type fructan degradation capacity determines cross-feeding interactions between bifidobacteria and Faecalibacterium prausnitzii, Int. J. Food Microbiol., 231, 76, 10.1016/j.ijfoodmicro.2016.05.015 · DOI
  101. Morgan, 2012, Dysfunction of the intestinal microbiome in inflammatory bowel disease and treatment, Genome Biol., 13, R79, 10.1186/gb-2012-13-9-r79 · DOI · Paper page
  102. NCBI Resource Coordinators, 2014, Database resources of the National Center for Biotechnology Information, Nucleic Acids Res., 42, D7, 10.1093/nar/gkt1146 · DOI · Paper page
  103. Nemoto, 2012, Reduced diversity and imbalance of fecal microbiota in patients with ulcerative colitis, Dig. Dis. Sci., 57, 2955, 10.1007/s10620-012-2236-y · DOI
  104. Neyrinck, 2012, Wheat-derived arabinoxylan oligosaccharides with prebiotic effect increase satietogenic gut peptides and reduce metabolic endotoxemia in diet-induced obese mice, Nutr. Diabetes, 2, e28, 10.1038/nutd.2011.24 · DOI
  105. Nielsen, 2014, Diets high in resistant starch and arabinoxylan modulate digestion processes and SCFA pool size in the large intestine and faecal microbial composition in pigs, Br. J. Nutr., 112, 1837, 10.1017/S000711451400302X · DOI
  106. Omori, 2010, Characterization of recombinant β-fructofuranosidase from Bifidobacterium adolescentis G1, Chem. Centr. J., 4, 9, 10.1186/1752-153X-4-9 · DOI
  107. Ou, 2014, Feruloylated oligosaccharides: structure, metabolism and function, J. Funct. Foods, 7, 90, 10.1016/j.jff.2013.09.028 · DOI
  108. Palframan, 2003, Carbohydrate preferences of Bifidobacterium species isolated from the human gut, Curr. Issues Intest. Microbiol., 4, 71
  109. Pamer, 2014, Fecal microbiota transplantation: effectiveness, complexities, and lingering concerns, Mucosal Immunol., 7, 210, 10.1038/mi.2013.117 · DOI
  110. Parche, 2007, Sugar transport systems of Bifidobacterium longum NCC2705, J. Mol. Microbiol. Biotechnol., 12, 9, 10.1159/000096455 · DOI
  111. Pastell, 2009, In vitro fermentation of arabinoxylan-derived carbohydrates by bifidobacteria and mixed faecal microbiota, J. Agric. Food Chem., 57, 8598, 10.1021/jf901397b · DOI
  112. Pokusaeva, 2011, Carbohydrate metabolism in Bifidobacteria, Genes Nutr., 6, 285, 10.1007/s12263-010-0206-6 · DOI
  113. Pollet, 2012, In vitro fermentation of arabinoxylan oligosaccharides and low molecular mass arabinoxylans with different structural properties from wheat (Triticum aestivum L.) bran and psyllium (Plantago ovata Forsk) seed husk, J. Agric. Food Chem., 60, 946, 10.1021/jf203820j · DOI
  114. Qiu, 2013, Faecalibacterium prausnitzii upregulates regulatory T cells and anti-inflammatory cytokines in treating TNBS-induced colitis, J. Crohns Colitis, 7, e558, 10.1016/j.crohns.2013.04.002 · DOI · Paper page
  115. Quévrain, 2016, Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn's disease, Gut, 65, 415, 10.1136/gutjnl-2014-307649 · DOI
  116. Richards, 2016, The effects of short-chain fatty acids on the cardiovascular system, Pharma Nutr, 4, 68, 10.1016/j.phanu.2016.02.001 · DOI
  117. Ridaura, 2013, Gut microbiota from twins discordant for obesity modulate metabolism in mice, Science, 341, 1241214, 10.1126/science.1241214 · DOI · Paper page
  118. Rivière, 2015, Mutual cross-feeding interactions between Bifidobacterium longum NCC2705 and Eubacterium rectale ATCC 33656 explain the bifidogenic and butyrogenic effects of arabinoxylan-oligosaccharides, Appl. Environ. Microbiol., 81, 7767, 10.1128/AEM.02089-15 · DOI
  119. Rivière, 2014, The ability of bifidobacteria to degrade arabinoxylan oligosaccharide constituents and derived oligosaccharides is strain dependent, Appl. Environ. Microbiol., 80, 204, 10.1128/AEM.02853-13 · DOI
  120. Roberfroid, 2005, Introducing inulin-type fructans, Br. J. Nutr., 93, S13, 10.1079/bjn20041350 · DOI
  121. Roberfroid, 2007, Inulin-type fructans: functional food ingredients, J. Nutr., 137, 2493, 10.1201/9780203504932 · DOI
  122. Rossi, 2011, Probiotic properties of bifidobacteria, 97
  123. Saez-Lara, 2015, The role of probiotic lactic acid bacteria and bifidobacteria in the prevention and treatment of inflammatory bowel disease and other related diseases: a systematic review of randomized human clinical trials, Biomed. Res. Int., 2015, 505878, 10.1155/2015/505878 · DOI · Paper page
  124. Salminen, 2012, Probiotics and prebiotics: health claim substantiation, Microb. Ecol. Health Dis., 23, 18568, 10.3402/mehd.v23i0.18568 · DOI · Paper page
  125. Sanchez, 2009, Arabinoxylan-oligosaccharides (AXOS) affect the protein/carbohydrate fermentation balance and microbial population dynamics of the simulator of human intestinal microbial ecosystem, Microb. Biotechnol., 2, 101, 10.1111/j.1751-7915.2008.00064.x · DOI
  126. Schaafsma, 2015, Significance of inulin fructans in the human diet, Compr. Rev. Food Sci. Food Saf., 14, 37, 10.1111/1541-4337.12119 · DOI
  127. Schell, 2002, The genome sequence of Bifidobacterium longum reflects its adaptation to the human gastrointestinal tract, Proc. Natl. Acad. Sci. U.S.A., 99, 14422, 10.1073/pnas.212527599 · DOI
  128. Scott, 2015, Manipulating the gut microbiota to maintain health and treat disease, Microb. Ecol. Health Dis., 26, 25877, 10.3402/mehd.v26.25877 · DOI
  129. Scott, 2011, Substrate-driven gene expression in Roseburia inulinivorans: importance of inducible enzymes in the utilization of inulin and starch, Proc. Natl. Acad. Sci. U.S.A., 1, 4672, 10.1073/pnas.1000091107 · DOI
  130. Scott, 2014, Prebiotic stimulation of human colonic butyrate-producing bacteria and bifidobacteria, in vitro, FEMS Microbiol. Ecol., 87, 30, 10.1111/1574-6941.12186 · DOI
  131. Selak, 2016, Inulin-type fructan fermentation by bifidobacteria depends on the strain rather than the species and region in the human intestine, Appl. Microbiol. Biotechnol., 100, 4097, 10.1007/s00253-016-7351-9 · DOI
  132. Slavin, 2013, Fiber and prebiotics: mechanisms and health benefits, Nutrients, 5, 1417, 10.3390/nu5041417 · DOI · Paper page
  133. Snelders, 2014, Structural features and feruloylation modulate the fermentability and evolution of antioxidant properties of arabinoxylanoligosaccharides during in vitro fermentation by human gut derived microbiota, J. Funct. Foods, 10, 1, 10.1016/j.jff.2014.05.011 · DOI
  134. Swennen, 2006, Large-scale production and characterisation of wheat bran arabinoxylooligosaccharides, J. Sci. Food Agric., 86, 1722, 10.1002/jsfa.2470 · DOI
  135. Tannock, 2010, Analysis of bifidobacterial populations in bowel ecology studies, 1
  136. Tojo, 2014, Intestinal microbiota in health and disease: role of bifidobacteria in gut homeostasis, World J. Gastroenterol., 20, 15163, 10.3748/wjg.v20.i41.15163 · DOI · Paper page
  137. Tralongo, 2014, The role of butyric acid as a protective agent against inflammatory bowel diseases, Euromediterranean Biomed. J., 9, 24, 10.3269/1970-5492.2014.9.4 · DOI
  138. Tuohy, 2015, The microbiota of the human gastrointestinal tract: a molecular view, 1, 10.1016/B978-0-12-407825-3.00001-0 · DOI
  139. Turroni, 2015, Glycan cross-feeding activities between bifidobacteria under in vitro conditions, Front. Microbiol., 6, 10.3389/fmicb.2015.01030 · DOI
  140. Van Craeyveld, 2008, Structurally different wheat-derived arabinoxylooligosaccharides have different prebiotic and fermentation properties in rats, J. Nutr., 138, 2348, 10.3945/jn.108.094367 · DOI
  141. Van den Abbeele, 2013a, Butyrate-producing Clostridium cluster XIVa species specifically colonize mucins in an in vitro gut model, ISME J., 7, 949, 10.1038/ismej.2012.158 · DOI · Paper page
  142. Van den Abbeele, 2011, Arabinoxylans and inulin differentially modulate the mucosal and luminal gut microbiota and mucin-degradation in humanized rats, Environ. Microbiol., 13, 2667, 10.1111/j.1462-2920.2011.02533.x · DOI
  143. Van den Abbeele, 2013b, Prebiotics, faecal transplants and microbial network units to stimulate biodiversity of the human gut microbiome, Microb. Biotechnol., 6, 335, 10.1111/1751-7915.12049 · DOI
  144. van den Broek, 2008, Bifidobacterium carbohydrases - their role in breakdown and synthesis of (potential) prebiotics, Nutr. Food. Res., 52, 146, 10.1002/mnfr.200700121 · DOI
  145. van den Broek, 2008, Bifidobacterium glycoside hydrolases and (potential) prebiotics, Innov. Food Sci. Emerg. Technol., 9, 401, 10.1016/j.ifset.2007.12.006 · DOI
  146. Van der Meulen, 2006a, Kinetic analysis of bifidobacterial metabolism reveals a minor role for succinic acid in the regeneration of NAD+ through its growth-associated production, Appl. Environ. Microbiol., 72, 5204, 10.1128/AEM.00146-06 · DOI
  147. Van der Meulen, 2004, Short fractions of oligofructose are preferentially metabolized by Bifidobacterium animalis DN-173 010, Appl. Environ. Microbiol., 70, 1923, 10.1128/AEM.70.4.1923-1930.2004 · DOI
  148. Van der Meulen, 2006b, In vitro kinetic analysis of oligofructose consumption by Bacteroides and Bifidobacterium spp. indicates different degradation mechanisms, Appl. Environ. Microbiol., 72, 1006, 10.1128/AEM.72.2.1006-1012.2006 · DOI
  149. Van Laere, 2000, Fermentation of plant cell wall derived polysaccharides and their corresponding oligosaccharides by intestinal bacteria, J. Agric. Food Chem., 48, 1644, 10.1021/jf990519i · DOI · Paper page
  150. Velasquez-Manoff, 2015, Gut microbiome: the peacekeepers, Nature, 518, S3, 10.1038/518S3a · DOI
  151. Ventura, 2011, Bifidobacterial ecology and comparative genomics: perspectives and prospects, 31
  152. Ventura, 2014, Bifidobacteria and humans: our special friends, from ecological to genomics perspectives, J. Sci. Food Agric., 94, 163, 10.1002/jsfa.6356 · DOI
  153. Verbeke, 2014, Prebiotics and synbiotics: how do they affect health?, 47, 10.2217/ebo.13.500 · DOI
  154. Verspreet, 2016, A critical look at prebiotics within the dietary fiber concept, Annu. Rev. Food Sci. Technol., 7, 167, 10.1146/annurev-food-081315-032749 · DOI
  155. Vital, 2014, Revealing the bacterial butyrate synthesis pathways by analyzing (meta)genomic data, MBio, 5, e00889, 10.1128/mBio.00889-14 · DOI
  156. Walker, 2014, Phylogeny, culturing, and metagenomics of the human gut microbiota, Trends Microbiol., 22, 267, 10.1016/j.tim.2014.03.001 · DOI · Paper page
  157. Walton, 2012, A randomised, double-blind, placebo controlled cross-over study to determine the gastrointestinal effects of consumption of arabinoxylan-oligosaccharides enriched bread in healthy volunteers, Nutr. J., 11, 36, 10.1186/1475-2891-11-36 · DOI
  158. Warchol, 2002, Characterization of a purified beta-fructofuranosidase from Bifidobacterium infantis ATCC 15697, Lett. Appl. Microbiol., 35, 462, 10.1046/j.1472-765X.2002.01224.x · DOI
  159. Wikoff, 2009, Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites, Proc. Natl. Acad. Sci. U.S.A., 106, 3698, 10.1073/pnas.0812874106 · DOI · Paper page
  160. Yang, 2013, In vitro characterization of the impact of selected dietary fibers on fecal microbiota composition and short chain fatty acid production, Anaerobe, 23, 74, 10.1016/j.anaerobe.2013.06.012 · DOI · Paper page
  161. Zoetendal, 2012, The human small intestinal microbiota is driven by rapid uptake and conversion of simple carbohydrates, ISME J., 6, 1415, 10.1038/ismej.2011.212 · DOI · Paper page

Cited by

See all 1,726

Metadata

Authors
Rivière, A., Selak, M., Lantin, D., Leroy, F., & De Vuyst, L.
Venue
Frontiers in Microbiology
Publisher
Frontiers Media SA
Published
2016-06-28
Volume
7
Pages
979-979
ISSN
1664-302X (ISSN-L)
DOI
10.3389/fmicb.2016.00979
OpenAlex
W2470512478
Cited by
1,726
References
28
FWCI
44.24
Type
journal article
Language
en
Open access
gold
Funders
  • Fonds Wetenschappelijk Onderzoek (BRADING IWT130028)
  • Vrije Universiteit Brussel (SRP7, IRP2, and IOF342)
  • Agentschap voor Innovatie door Wetenschap en Technologie

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review

How to cite

Cite CoChat for the checks on this page, and the paper for its own findings.

This page
CoChat. (2026). Citation check: Bifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut. https://app.cochat.ai/papers/10.3389/fmicb.2016.00979
The paper
Rivière, A., Selak, M., Lantin, D., Leroy, F., & De Vuyst, L. (2016). Bifidobacteria and Butyrate-Producing Colon Bacteria: Importance and Strategies for Their Stimulation in the Human Gut. Frontiers in Microbiology. https://doi.org/10.3389/fmicb.2016.00979

Data sources

Bibliographic data: Semantic Scholar, OpenAlex, Crossref.

Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).

Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.