Safety of Novel Microbes for Human Consumption: Practical Examples of Assessment in the European Union

An obesity-associated gut microbiome with increased capacity for energy harvest

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Untitled work

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Cross-talk between <i>Akkermansia muciniphila</i> and intestinal epithelium controls diet-induced obesity

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<i>Faecalibacterium prausnitzii</i> is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

Sokol, H., Pigneur, B., Watterlot, L., Lakhdari, O., Bermúdez-Humarán, L. G., Gratadoux, J.-J., Blugeon, S., Bridonneau, C., Furet, J.-P., Corthier, G., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0804812105 · Cited by 4,413 · see citing works

Bacteroides : the Good, the Bad, and the Nitty-Gritty

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The gut microbiota and host health: a new clinical frontier

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Altered fecal microbiota composition in patients with major depressive disorder

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A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice

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Akkermansia muciniphila gen. nov., sp. nov., a human intestinal mucin-degrading bacterium

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H OW H OST -M ICROBIAL I NTERACTIONS S HAPE THE N UTRIENT E NVIRONMENT OF THE M AMMALIAN I NTESTINE

Hooper, L. V., Midtvedt, T., & Gordon, J. I. (2002) · Annual Review of Nutrition · doi:10.1146/annurev.nutr.22.011602.092259 · Cited by 1,623 · see citing works

Mucolytic Bacteria With Increased Prevalence in IBD Mucosa Augment In Vitro Utilization of Mucin by Other Bacteria

Png, C. W., Lindén, S. K., Gilshenan, K. S., Zoetendal, E. G., McSweeney, C. S., Sly, L. I., McGuckin, M. A., & Florin, T. H. J. (2010) · American Journal of Gastroenterology · doi:10.1038/ajg.2010.281 · Cited by 1,364 · see citing works

Faecalibacterium prausnitzii and human intestinal health

Miquel, S., Martín, R., Rossi, O., Bermúdez‐Humarán, L. G., Chatel, J., Sokol, H., Thomas, M., Wells, J. M., & Langella, P. (2013) · Current Opinion in Microbiology · doi:10.1016/j.mib.2013.06.003 · Cited by 1,239 · see citing works

Evidence for a core gut microbiota in the zebrafish

Roeselers, G., Mittge, E., Stephens, W. Z., Parichy, D. M., Cavanaugh, C. M., Guillemin, K. J., & Rawls, J. F. (2011) · The ISME Journal · doi:10.1038/ismej.2011.38 · Cited by 1,145 · see citing works

Human Gut Microbiota Changes Reveal the Progression of Glucose Intolerance

Zhang, X., Shen, D., Fang, Z., Jie, Z., Qiu, X., Zhang, C., Chen, Y., & Ji, L. (2013) · PLoS ONE · doi:10.1371/journal.pone.0071108 · Cited by 946 · see citing works

The Rebirth of Culture in Microbiology through the Example of Culturomics To Study Human Gut Microbiota

Lagier, J., Hugon, P., Khelaifia, S., Fournier, P., Scola, B. L., & Raoult, D. (2015) · Clinical Microbiology Reviews · doi:10.1128/cmr.00014-14 · Cited by 839 · see citing works

Akkermansia muciniphila inversely correlates with the onset of inflammation, altered adipose tissue metabolism and metabolic disorders during obesity in mice

Schneeberger, M., Everard, A., Gómez-Valadés, A. G., Matamoros, S., Ramírez, S., Delzenne, N. M., Gomis, R., Claret, M., & Cani, P. D. (2015) · Scientific Reports · doi:10.1038/srep16643 · Cited by 798 · see citing works

Roseburia Spp.: A Marker of Health?

Tamanai‐Shacoori, Z., Smida, I., Bousarghin, L., Loréal, O., Meuric, V., Fong, S. B., Bonnaure‐Mallet, M., & Jolivet‐Gougeon, A. (2017) · Future Microbiology · doi:10.2217/fmb-2016-0130 · Cited by 751 · see citing works

Microbes inside—from diversity to function: the case of Akkermansia

Belzer, C., & de Vos, W. M. (2012) · The ISME Journal · doi:10.1038/ismej.2012.6 · Cited by 715 · see citing works

The immunomodulatory properties of probiotic microorganisms beyond their viability (ghost probiotics: proposal of paraprobiotic concept)

Taverniti, V., & Guglielmetti, S. (2011) · Genes &amp; Nutrition · doi:10.1007/s12263-011-0218-x · Cited by 703 · see citing works

Intestinal microbiome is related to lifetime antibiotic use in Finnish pre-school children

Korpela, K., Salonen, A., Virta, L. J., Kekkonen, R. A., Forslund, K., Bork, P., & de Vos, W. M. (2016) · Nature Communications · doi:10.1038/ncomms10410 · Cited by 698 · see citing works

The Mucin Degrader Akkermansia muciniphila Is an Abundant Resident of the Human Intestinal Tract

Derrien, M., Collado, M. C., Amor, K. B., Salminen, S., & de Vos, W. M. (2007) · Applied and Environmental Microbiology · doi:10.1128/aem.01226-07 · Cited by 659 · see citing works

Stool microbiome and metabolome differences between colorectal cancer patients and healthy adults

Weir, T. L., Manter, D. K., Sheflin, A. M., Barnett, B. A., Heuberger, A. L., & Ryan, E. P. (2013) · PLoS ONE · doi:10.1371/journal.pone.0070803 · Cited by 642 · see citing works

Propionate as a health-promoting microbial metabolite in the human gut

Hosseini, E., Grootaert, C., Verstraete, W., & de Wiele, T. V. (2011) · Nutrition Reviews · doi:10.1111/j.1753-4887.2011.00388.x · Cited by 586 · see citing works

Mucin-bacterial interactions in the human oral cavity and digestive tract

Derrien, M., van Passel, M. W. J., van de Bovenkamp, J. H. B., Schipper, R., de Vos, W., & Dekker, J. (2010) · Gut Microbes · doi:10.4161/gmic.1.4.12778 · Cited by 556 · see citing works

Microbiota of Human Breast Tissue

Urbaniak, C., Cummins, J., Brackstone, M., Macklaim, J. M., Gloor, G. B., Baban, C. K., Scott, L., O'Hanlon, D. M., Burton, J. P., Francis, K. P., et al. (2014) · Applied and Environmental Microbiology · doi:10.1128/aem.00242-14 · Cited by 552 · see citing works

The Microbiota of the Gut in Preschool Children With Normal and Excessive Body Weight

Karlsson, C., Önnerfält, J., Xu, J., Molin, G., Ahrné, S., & Thorngren‐Jerneck, K. (2012) · Obesity · doi:10.1038/oby.2012.110 · Cited by 536 · see citing works

Akkermansia muciniphila Adheres to Enterocytes and Strengthens the Integrity of the Epithelial Cell Layer

Reunanen, J., Kainulainen, V., Huuskonen, L., Ottman, N., Belzer, C., Huhtinen, H., de Vos, W. D., & Satokari, R. (2015) · Applied and Environmental Microbiology · doi:10.1128/aem.04050-14 · Cited by 510 · see citing works

Milk and dairy products: good or bad for human health? An assessment of the totality of scientific evidence

Thorning, T. K., Raben, A., Tholstrup, T., Soedamah‐Muthu, S. S., Givens, D. I., & Astrup, A. V. (2016) · Food & Nutrition Research · doi:10.3402/fnr.v60.32527 · Cited by 485 · see citing works

Update of the list of QPS‐recommended biological agents intentionally added to food or feed as notified to EFSA 13: suitability of taxonomic units notified to EFSA until September 2020

(BIOHAZ), E. P. O. B. H., Koutsoumanis, K., Allende, A., Álvarez‐Ordóñez, A., Bolton, D., Bover‐Cid, S., Chemaly, M., Davies, R., Cesare, A. D., Hilbert, F., et al. (2021) · EFSA Journal · doi:10.2903/j.efsa.2021.6377 · Cited by 443 · see citing works

The Genome of Akkermansia muciniphila, a Dedicated Intestinal Mucin Degrader, and Its Use in Exploring Intestinal Metagenomes

van Passel, M. W. J., Kant, R., Zoetendal, E. G., Plugge, C. M., Derrien, M., Malfatti, S., Chain, P., Woyke, T., Palva, A., de Vos, W. M., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0016876 · Cited by 425 · see citing works

Paraprobiotics: Evidences on their ability to modify biological responses, inactivation methods and perspectives on their application in foods

de Almada, C. N., de Almada, C. N., Martinez, R. C. R., & Sant’Ana, A. S. (2016) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2016.09.011 · Cited by 425 · see citing works

A dynamic partnership: Celebrating our gut flora

Sears, C. L. (2005) · Anaerobe · doi:10.1016/j.anaerobe.2005.05.001 · Cited by 415 · see citing works

Postbiotics: what else?

Tsilingiri, K., & Rescigno, M. (2012) · Beneficial Microbes · doi:10.3920/bm2012.0046 · Cited by 396 · see citing works

Scientific Opinion on the maintenance of the list of QPS biological agents intentionally added to food and feed (2013 update)

(BIOHAZ), E. P. O. B. H. (2013) · EFSA Journal · doi:10.2903/j.efsa.2013.3449 · Cited by 326 · see citing works

Guidance on the preparation and presentation of an application for authorisation of a novel food in the context of Regulation (EU) 2015/2283

EFSA Panel on Dietetic Products, N. A. A. (., Turck, D., Bresson, J., Burlingame, B., Dean, T., Fairweather‐Tait, S. J., Heinonen, M., Hirsch‐Ernst, K. I., Mangelsdorf, I., McArdle, H. J., et al. (2016) · EFSA Journal · doi:10.2903/j.efsa.2016.4594 · Cited by 307 · see citing works

Sub-clinical detection of gut microbial biomarkers of obesity and type 2 diabetes

Yassour, M., Lim, M. Y., Yun, H. S., Tickle, T. L., Sung, J., Song, Y., Lee, K., Franzosa, E. A., Morgan, X. C., Gevers, D., et al. (2016) · Genome Medicine · doi:10.1186/s13073-016-0271-6 · Cited by 286 · see citing works

Manipulating the gut microbiota to maintain health and treat disease

Scott, K. P., Antoine, J., Midtvedt, T., & van Hemert, S. (2015) · Microbial Ecology in Health and Disease · doi:10.3402/mehd.v26.25877 · Cited by 284 · see citing works

Probiotics and health: An evidence-based review

Aureli, P., Capurso, L., Castellazzi, A. M., Clerici, M., Giovannini, M., Morelli, L., Poli, A., Pregliasco, F. E., Salvini, F. M., & Zuccotti, G. (2011) · Pharmacological Research · doi:10.1016/j.phrs.2011.02.006 · Cited by 281 · see citing works

Fermented foods, microbiota, and mental health: ancient practice meets nutritional psychiatry

Selhub, E. M., Logan, A. C., & Bested, A. C. (2014) · Journal of Physiological Anthropology · doi:10.1186/1880-6805-33-2 · Cited by 280 · see citing works

Maternal weight and excessive weight gain during pregnancy modify the immunomodulatory potential of breast milk

Collado, M. C., Laitinen, K., Salminen, S., & Isolauri, E. (2012) · Pediatric Research · doi:10.1038/pr.2012.42 · Cited by 270 · see citing works

Postprandial remodeling of the gut microbiota in Burmese pythons

Costello, E. K., Gordon, J. I., Secor, S. M., & Knight, R. D. (2010) · The ISME Journal · doi:10.1038/ismej.2010.71 · Cited by 267 · see citing works

Oral treatment with Eubacterium hallii improves insulin sensitivity in db/db mice

Udayappan, S. D., Mannerås-Holm, L., Chaplin, A. M. L., Belzer, C., Herrema, H., Dallinga‐Thie, G. M., Duncan, S. H., Stroes, E. S. G., Groen, A. K., Flint, H. J., et al. (2016) · npj Biofilms and Microbiomes · doi:10.1038/npjbiofilms.2016.9 · Cited by 264 · see citing works

Scientific Opinion on the evaluation of allergenic foods and food ingredients for labelling purposes

EFSA Panel on Dietetic Products, N. A. A. (. (2014) · EFSA Journal · doi:10.2903/j.efsa.2014.3894 · Cited by 243 · see citing works

Microbial Anti-Inflammatory Molecule (MAM) from Faecalibacterium prausnitzii Shows a Protective Effect on DNBS and DSS-Induced Colitis Model in Mice through Inhibition of NF-κB Pathway

Breyner, N. M., Michon, C., de Sousa, C. S., Boas, P. C. B. V., Chain, F., Azevedo, V., Langella, P., & Chatel, J. (2017) · Frontiers in Microbiology · doi:10.3389/fmicb.2017.00114 · Cited by 238 · see citing works

Lactobacillus rhamnosusCNCM I-3690 and the commensal bacteriumFaecalibacterium prausnitziiA2-165 exhibit similar protective effects to induced barrier hyper-permeability in mice

Laval, L., Martín, R., Natividad, J. M., Chain, F., Miquel, S., de Maredsous, C. D., Capronnier, S., Sokol, H., Verdu, E. F., Vlieg, J. E. T. V. H., et al. (2014) · Gut Microbes · doi:10.4161/19490976.2014.990784 · Cited by 215 · see citing works

Honeybees and beehives are rich sources for fructophilic lactic acid bacteria

Endo, A., & Salminen, S. (2013) · Systematic and Applied Microbiology · doi:10.1016/j.syapm.2013.06.002 · Cited by 213 · see citing works

Isolation and characterization of fructophilic lactic acid bacteria from fructose-rich niches

Endo, A., Futagawa-Endo, Y., & Dicks, L. M. T. (2009) · Systematic and Applied Microbiology · doi:10.1016/j.syapm.2009.08.002 · Cited by 198 · see citing works

Scientific Opinion on the maintenance of the list of QPS biological agents intentionally added to food and feed (2010 update)

(BIOHAZ), E. O. B. H. (2010) · EFSA Journal · doi:10.2903/j.efsa.2010.1944 · Cited by 198 · see citing works

Qualified presumption of safety (QPS): a generic risk assessment approach for biological agents notified to the European Food Safety Authority (EFSA)

Leuschner, R. G. K., Robinson, T. P., Hugas, M., Cocconcelli, P. S., Richard-Forget, F. C., Klein, G., Licht, T. R., Nguyen‐The, C., Querol, A., Richardson, M. D., et al. (2010) · Trends in Food Science & Technology · doi:10.1016/j.tifs.2010.07.003 · Cited by 174 · see citing works

Safety of probiotic bacteria

Seppo Salminen, E. I. (2003) · CRC Press eBooks · doi:10.1201/9780203634523-16 · Cited by 172 · see citing works

Spontaneous organic cocoa bean box fermentations in Brazil are characterized by a restricted species diversity of lactic acid bacteria and acetic acid bacteria

Papalexandratou, Z., Vrancken, G., Bruyne, K. D., Vandamme, P. A. R., & Vuyst, L. D. (2011) · Food Microbiology · doi:10.1016/j.fm.2011.06.003 · Cited by 155 · see citing works

Adaptation of Akkermansia muciniphila to the Oxic-Anoxic Interface of the Mucus Layer

Ouwerkerk, J. P., van der Ark, K. C. H., Davids, M., Claassens, N. J., Robert-Finestra, T., de Vos, W. M., & Belzer, C. (2016) · Applied and Environmental Microbiology · doi:10.1128/aem.01641-16 · Cited by 155 · see citing works

Reclassification of the genus Leuconostoc and proposals of Fructobacillus fructosus gen. nov., comb. nov., Fructobacillus durionis comb. nov., Fructobacillus ficulneus comb. nov. and Fructobacillus pseudoficulneus comb. nov.

Endo, A., & Okada, S. (2008) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/ijs.0.65609-0 · Cited by 152 · see citing works

Increased gut microbiota diversity and abundance of Faecalibacterium prausnitzii and Akkermansia after fasting: a pilot study

Remely, M., Hippe, B., Geretschläger, I. C., Stegmayer, S., Höfinger, I., & Haslberger, A. G. (2015) · Wiener klinische Wochenschrift · doi:10.1007/s00508-015-0755-1 · Cited by 142 · see citing works

The effect of Clostridium butyricum MIYAIRI on the prevention of pouchitis and alteration of the microbiota profile in patients with ulcerative colitis

Yasueda, A., Mizushima, T., Nezu, R., Sumi, R., Tanaka, M., Nishimura, J., Kai, Y., Hirota, M., Osawa, H., Nakajima, K., et al. (2015) · Surgery Today · doi:10.1007/s00595-015-1261-9 · Cited by 141 · see citing works

Gut microbiota modulation: probiotics, antibiotics or fecal microbiota transplantation?

Cammarota, G., Ianiro, G., Bibbò, S., & Gasbarrini, A. (2014) · Internal and Emergency Medicine · doi:10.1007/s11739-014-1069-4 · Cited by 136 · see citing works

Dynamics and species diversity of communities of lactic acid bacteria and acetic acid bacteria during spontaneous cocoa bean fermentation in vessels

Lefeber, T., Gobert, W., Vrancken, G., Camu, N., & Vuyst, L. D. (2010) · Food Microbiology · doi:10.1016/j.fm.2010.10.010 · Cited by 135 · see citing works

Guidance on the preparation and submission of an application for authorisation of a novel food in the context of Regulation (EU) 2015/22831 (Revision 1)2

Products, N. E. P. O. D., Nutrition, Allergies, Turck, D., Bresson, J., Burlingame, B., Dean, T., Fairweather‐Tait, S. J., Heinonen, M., Hirsch‐Ernst, K. I., et al. (2021) · EFSA Journal · doi:10.2903/j.efsa.2021.6555 · Cited by 135 · see citing works

Iron Modulates Butyrate Production by a Child Gut Microbiota In Vitro

Dostal, A., Lacroix, C., Bircher, L., Pham, V. T., Follador, R., Zimmermann, M. B., & Chassard, C. (2015) · mBio · doi:10.1128/mbio.01453-15 · Cited by 134 · see citing works

Akkermansia muciniphila: a novel functional microbe with probiotic properties

Gómez-Gallego, C., Pohl, S., Salminen, S., de Vos, W. M., & Kneifel, W. (2016) · Beneficial Microbes · doi:10.3920/bm2016.0009 · Cited by 130 · see citing works

Bacteroides xylanisolvens sp. nov., a xylan-degrading bacterium isolated from human faeces

Chassard, C., Delmas, E., Lawson, P. A., et al. (2008) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/ijs.0.65504-0 · Cited by 121 · see citing works

Fermented Foods: Patented Approaches and Formulations for Nutritional Supplementation and Health Promotion

Borresen, E. C., Henderson, A. J., Kumar, A., Weir, T. L., & Ryan, E. P. (2012) · Recent Patents on Food Nutrition & Agriculture · doi:10.2174/2212798411204020134 · Cited by 118 · see citing works

In vitro fermentation of alginate and its derivatives by human gut microbiota

Li, M., Li, G., Shang, Q., Chen, X., Liu, W., Pi, X., Zhu, L., Yin, Y., Yu, G., & Wang, X. (2016) · Anaerobe · doi:10.1016/j.anaerobe.2016.02.003 · Cited by 117 · see citing works

Characterization and emended description of Lactobacillus kunkeei as a fructophilic lactic acid bacterium

Endo, A., Irisawa, T., Futagawa-Endo, Y., Takano, K., du Toit, M., Okada, S., & Dicks, L. M. T. (2011) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/ijs.0.031054-0 · Cited by 110 · see citing works

Molecular diversity of leuconostoc mesenteroides and leuconostoc citreum isolated from traditional french cheeses as revealed by RAPD fingerprinting, 16S rDNA sequencing and 16S rDNA fragment amplification.

Çıbık, R., Lepage, E., & Tailliez, P. (2000) · Systematic and Applied Microbiology · doi:10.1016/s0723-2020(00)80014-4 · Cited by 104 · see citing works

Fructophilic Lactobacillus kunkeei and Lactobacillus brevis Isolated from Fresh Flowers, Bees and Bee-hives

Neveling, D. P., Endo, A., & Dicks, L. M. T. (2012) · Current Microbiology · doi:10.1007/s00284-012-0186-4 · Cited by 100 · see citing works

Dietary fibre degradation and fermentation by two xylanolytic bacteria Bacteroides xylanisolvens XB1A T and Roseburia intestinalis XB6B4 from the human intestine

Mirande, C., Kadlecikova, E., Matulová, M., Capek, P., Bernalier‐Donadille, A., Forano, É., & Béra‐Maillet, C. (2010) · Journal of Applied Microbiology · doi:10.1111/j.1365-2672.2010.04671.x · Cited by 98 · see citing works

Early colonization of functional groups of microbes in the infant gut

Pham, V. T., Lacroix, C., Braegger, C., & Chassard, C. (2016) · Environmental Microbiology · doi:10.1111/1462-2920.13316 · Cited by 98 · see citing works

Isolation and Characterization of Faecalibacterium prausnitzii from Calves and Piglets

Foditsch, C., Santos, T. M. A., Teixeira, A. G. V., Pereira, R. V. V., Dias, J. M., Gaeta, N. C., & Bicalho, R. C. (2014) · PLoS ONE · doi:10.1371/journal.pone.0116465 · Cited by 95 · see citing works

Clostridium butyricum MIYAIRI 588 shows antitumor effects by enhancing the release of TRAIL from neutrophils through MMP-8

SHINNOH, M., Horinaka, M., Yasuda, T., Yoshikawa, S., Morita, M., Yamada, T., Miki, T., & Sakai, T. (2013) · International Journal of Oncology · doi:10.3892/ijo.2013.1790 · Cited by 93 · see citing works

Live F aecalibacterium prausnitzii in an apical anaerobic model of the intestinal epithelial barrier

Ulluwishewa, D., Anderson, R. C., Young, W., McNabb, W. C., van Baarlen, P., Moughan, P. J., Wells, J. M., & Roy, N. C. (2014) · Cellular Microbiology · doi:10.1111/cmi.12360 · Cited by 90 · see citing works

Lactobacillus kunkeeiYB38 from honeybee products enhances IgA production in healthy adults

Asama, T., Arima, T., Gomi, T., Keishi, T., Tani, H., Kimura, Y., Tatefuji, T., & Hashimoto, K. (2015) · Journal of Applied Microbiology · doi:10.1111/jam.12889 · Cited by 85 · see citing works

Akkermansia glycaniphila sp. nov., an anaerobic mucin-degrading bacterium isolated from reticulated python faeces

Ouwerkerk, J. P., Aalvink, S., Belzer, C., & de Vos, W. M. (2016) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/ijsem.0.001399 · Cited by 84 · see citing works

Clostridium Butyricum CGMCC0313.1 Modulates Lipid Profile, Insulin Resistance and Colon Homeostasis in Obese Mice

Shang, H., Sun, J. T., & Chen, Y. Q. (2016) · PLoS ONE · doi:10.1371/journal.pone.0154373 · Cited by 81 · see citing works

Comparative genomics of Fructobacillus spp. and Leuconostoc spp. reveals niche-specific evolution of Fructobacillus spp.

Endo, A., Tanizawa, Y., Tanaka, N., Maeno, S., Kumar, H., Shiwa, Y., Okada, S., Yoshikawa, H., Dicks, L. M. T., Nakagawa, J., et al. (2015) · BMC Genomics · doi:10.1186/s12864-015-2339-x · Cited by 80 · see citing works

Genomic characterization of a fructophilic bee symbiont Lactobacillus kunkeei reveals its niche-specific adaptation

Maeno, S., Tanizawa, Y., Kanesaki, Y., Kubota, E., Kumar, H., Dicks, L. M. T., Salminen, S., Nakagawa, J., Arita, M., & Endo, A. (2016) · Systematic and Applied Microbiology · doi:10.1016/j.syapm.2016.09.006 · Cited by 78 · see citing works

Effect of <i>Clostridium butyricum</i> on fecal flora in <i>Helicobacter pylori</i> eradication therapy

Shimbo, I. (2005) · World Journal of Gastroenterology · doi:10.3748/wjg.v11.i47.7520 · Cited by 75 · see citing works

Lactobacillus florum sp. nov., a fructophilic species isolated from flowers

Endo, A., Futagawa-Endo, Y., Sakamoto, M., et al. (2009) · INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY · doi:10.1099/ijs.0.019067-0 · Cited by 73 · see citing works

Effects of High Amylose Maize Starch and Clostridium butyricum on Metabolism in Colonic Microbiota and Formation of Azoxymethane‐Induced Aberrant Crypt Foci in the Rat Colon

Nakanishi, S., Kataoka, K., Kuwahara, T., et al. (2003) · Microbiology and Immunology · doi:10.1111/j.1348-0421.2003.tb03469.x · Cited by 73 · see citing works

Preliminary Safety Evaluation of a New Bacteroides xylanisolvens Isolate

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The bacterial community in ‘taberna’ a traditional beverage of Southern Mexico

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Fructophilic lactic acid bacteria inhabit fructose-rich niches in nature

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Bacteroides Induce Higher IgA Production Than Lactobacillus by Increasing Activation-Induced Cytidine Deaminase Expression in B Cells in Murine Peyer’s Patches

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Potential protective effects ofClostridium butyricumon experimental gastric ulcers in mice

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Probiotics: a proactive approach to health. A symposium report

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A proposed framework for an appropriate evaluation scheme for microorganisms as novel foods with a health claim in Europe

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The Two Faces ofLeuconostoc mesenteroidesin Food Systems

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Safety assessment of the <i>Clostridium butyricum</i> MIYAIRI 588 ^® probiotic strain including evaluation of antimicrobial sensitivity and presence of <i>Clostridium</i> toxin genes in vitro and teratogenicity in vivo

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Mode of Birth Influences Preterm Infant Intestinal Colonization With Bacteroides Over the Early Neonatal Period

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Impact of oral consumption of heat-treated Bacteroides xylanisolvens DSM 23964 on the level of natural TFα-specific antibodies in human adults

Ulsemer, P., Toutounian, K., Kressel, G., Goletz, C., Schmidt, J., Karsten, U. R., Hahn, A., & Goletz, S. (2016) · Beneficial Microbes · doi:10.3920/bm2015.0143 · Cited by 50 · see citing works

Novel Probiotics and Prebiotics: How Can They Help in Human Gut Microbiota Dysbiosis?

Gómez-Gallego, C., & Salminen, S. (2016) · DOAJ (DOAJ: Directory of Open Access Journals) · Cited by 48 · see citing works

Akkermansia muciniphila

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Effects of heat-killed Lactobacillus kunkeei YB38 on human intestinal environment and bowel movement: a pilot study

Asama, T., Kimura, Y., Kono, T., Tatefuji, T., Hashimoto, K., & Benno, Y. (2016) · Beneficial Microbes · doi:10.3920/bm2015.0132 · Cited by 42 · see citing works

Clostridium butyricum reduce lipogenesis through bacterial wall components and butyrate

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Safety of Probiotic Bacteria

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Leuconostoc strains isolated from dairy products: Response against food stress conditions

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The presence of the anti-inflammatory protein MAM, from Faecalibacterium prausnitzii , in the intestinal ecosystem

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Scientific Opinion on the safety of ‘heat-treated milk products fermented with Bacteroides xylanisolvens DSM 23964’ as a novel food

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Safety and tolerance of Bacteroides xylanisolvens DSM 23964 in healthy adults

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Evaluation of different expression systems for the heterologous expression of pyranose 2-oxidase from Trametes multicolor in E. coli

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Identification and characterization of Lactobacillus florum strains isolated from South African grape and wine samples

Mtshali, P. S., Divol, B., & du Toit, M. (2011) · International Journal of Food Microbiology · doi:10.1016/j.ijfoodmicro.2011.10.023 · Cited by 23 · see citing works

Lactobacillus apinorum belongs to the fructophilic lactic acid bacteria

Maeno, S., Dicks, L. M. T., Nakagawa, J., & Endo, A. (2017) · Bioscience of Microbiota Food and Health · doi:10.12938/bmfh.17-008 · Cited by 23 · see citing works

Complete Genome Sequence of Akkermansia glycaniphila Strain Pyt T , a Mucin-Degrading Specialist of the Reticulated Python Gut

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Safety assessment of the commensal strain Bacteroides xylanisolvens DSM 23964

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Novel Probiotics and Prebiotics: How Can They Help in Human Gut Microbiota Dysbiosis?

Gallego, C. G., & Seppo, S. (2016) · Applied food biotechnology · doi:10.22037/afb.v3i2.11276 · Cited by 5 · see citing works

The International Scientific Association of Probiotics and Prebiotics (ISAPP) Consensus Statement on the Definition and Scope of Postbiotics

Salminen, S., Collado, M. C., Endo, A., Hill, C., Lebeer, S., Quigley, E. M. M., Sanders, M. E., Shamir, R., Swann, J. R., Szajewska, H., et al. (2021) · Nature Reviews Gastroenterology &amp; Hepatology · doi:10.1038/s41575-021-00440-6 · Cited by 2,488 · see citing works

The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics

Swanson, K. S., Gibson, G. R., Hutkins, R., Reimer, R. A., Reid, G., Verbeke, K., Scott, K. P., Holscher, H. D., Azad, M. B., Delzenne, N. M., et al. (2020) · Nature Reviews Gastroenterology &amp; Hepatology · doi:10.1038/s41575-020-0344-2 · Cited by 2,196 · see citing works

Shaping the Future of Probiotics and Prebiotics

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The Genus Enterococcus: Between Probiotic Potential and Safety Concerns—An Update

Hanchi, H., Mottawea, W., Sebei, K., & Hammami, R. (2018) · Frontiers in Microbiology · doi:10.3389/fmicb.2018.01791 · Cited by 569 · see citing works

Function of Akkermansia muciniphila in obesity: interactions with lipid metabolism, immune response and gut systems

Xu, Y., Wang, N., Tan, H.-Y., Li, S., Zhang, C., & Feng, Y. (2020) · Frontiers in Microbiology · doi:10.3389/fmicb.2020.00219 · Cited by 420 · see citing works

The Potential Impact of Probiotics on Human Health: An Update on Their Health-Promoting Properties

Maftei, N.-M., Raileanu, C. R., Balta, A. A., Ambrose, L., Boev, M., Marin, D. B., & Lisa, E. L. (2024) · Microorganisms · doi:10.3390/microorganisms12020234 · Cited by 381 · see citing works

Microbiota transplantation: Concept, methodology and strategy for its modernization

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Harms Reporting in Randomized Controlled Trials of Interventions Aimed at Modifying Microbiota: A Systematic Review

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Considerations for determining safety of probiotics: A USP perspective

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Live Biotherapeutic Products, A Road Map for Safety Assessment

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Preliminary Evaluation of the Safety and Probiotic Potential of Akkermansia muciniphila DSM 22959 in Comparison with Lactobacillus rhamnosus GG

Cozzolino, A., Vergalito, F., Tremonte, P., Iorizzo, M., Lombardi, S. J., Sorrentino, E., Luongo, D., Coppola, R., Di Marco, R., & Succi, M. (2020) · Microorganisms · doi:10.3390/microorganisms8020189 · Cited by 84 · see citing works

Legal aspects of microalgae in the European food sector

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Different Reactions in Each Enterotype Depending on the Intake of Probiotic Yogurt Powder

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WS08.06 Pilot study evaluating the potential of Akkermansia muciniphila and Faecalibacterium prausnitzii as cystic fibrosis-specific probiotics utilising patient-derived organoid models

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Reduced Akkermansia muciniphila and Faecalibacterium prausnitzii levels in the gut microbiota of children with allergic asthma

Demirci, M., Tokman, H. B., Uysal, H. K., Demiryas, S., Karakullukcu, A., Saribas, S., Cokugras, H., & Kocazeybek, B. S. (2019) · Allergologia et Immunopathologia · doi:10.1016/j.aller.2018.12.009 · Cited by 150 · see citing works

Dietary Factors and Modulation of Bacteria Strains of Akkermansia muciniphila and Faecalibacterium prausnitzii: A Systematic Review

Verhoog, S., Taneri, P. E., Roa‐Díaz, Z. M., Marques-Vidal, P. M., Troup, J. P., Bally, L., Franco, O. H., Glišić, M., & Muka, T. (2019) · Nutrients · doi:10.3390/nu11071565 · Cited by 205 · see citing works

The Role of Akkermansia muciniphila and Faecalibacterium prausnitzii in the Pathogenesis of Ulcerative Colitis and Crohn's Disease

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Alterations in the Abundance and Co-occurrence of Akkermansia muciniphila and Faecalibacterium prausnitzii in the Colonic Mucosa of Inflammatory Bowel Disease Subjects

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