Roles of the different sub-regions of the insular cortex in various phases of the decision-making process
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This paper presents a coherent account of the role of the insular cortex (IC) in decision-making. We follow a conceptualization of decision-making that is very close to one previously proposed by Ernst and Paulus (2005): that the decision process is a progression of four phases: (1) re-focusing attention; (2) evaluation; (3) action; and (4) outcome processing, and we present evidence for the insula's role in all these phases. We review the existing work on insula's functional anatomy that subdivides the IC into posterior, dorsal anterior and ventral anterior regions. We re-map the results provided by the existing literature into these subdivisions wherever possible, to identify the components' role in each decision making phase. In addition, we identify a self-regulating quality of the IC focused on harm avoidance.
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The insula plays a major role in all aspects of decision making.
“In addition to important interoceptive and homeostatic functions, the insula plays a major role in all aspects of decision making”
From The Insula: A Brain Stimulation Target for the Treatment of Addiction (2019) · cites this paper as Droutman et al., 2015
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Levin, I. P., Xue, G., Weller, J. A., Reimann, M., Lauriola, M., & Bechara, A. (2012) · Frontiers in Neuroscience · doi:10.3389/fnins.2012.00015 · Cited by 73 · see citing works
Self-citationOnce an island, now the focus of attention
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Cerebral Representation of the Relief of Itch by Scratching
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Toward an Affective Neuroscience Account of Financial Risk Taking
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Neural foundations of risk–return trade-off in investment decisions
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Reward skewness coding in the insula independent of probability and loss
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Pain, temperature, and the sense of the body
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The Insula: A Brain Stimulation Target for the Treatment of Addiction
Ibrahim, C., Rubin-Kahana, D. S., Pushparaj, A., Musiol, M., Blumberger, D. M., Daskalakis, Z. J., Zangen, A., & Le Foll, B. (2019) · Frontiers in Pharmacology · doi:10.3389/fphar.2019.00720 · Cited by 133 · see citing works
Glucagon-like peptide 1 agonist and effects on reward behaviour: A systematic review
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WAP: understanding the brain at software debugging
Duraes, J., Madeira, H., Castelhano, J., Duarte, C., & Branco, M. C. (2016) · 2016 IEEE 27th International Symposium on Software Reliability Engineering (ISSRE) · doi:10.1109/issre.2016.53 · Cited by 47 · see citing works
Altered response to risky decisions and reward in patients with obsessive–compulsive disorder
Moreira, P. S., Macoveanu, J., Marques, P., Coelho, A., Magalhães, R., Siebner, H. R., Soares, J. M., Sousa, N., & Morgado, P. (2020) · Journal of Psychiatry and Neuroscience · doi:10.1503/jpn.180226 · Cited by 26 · see citing works
- Authors
- Droutman, V., Bechara, A., & Read, S. J.
- Affiliations
- University of Southern California (US)
- Corresponding author
- Droutman, Vita
- Venue
- Frontiers in Behavioral Neuroscience
- Publisher
- Frontiers Media SA
- Published
- 2015-11-25
- Volume
- 9
- Pages
- 309-309
- ISSN
- 1662-5153 (ISSN-L)
- PMC
- PMC4658437
- OpenAlex
- W2182878959
- Cited by
- 131
- References
- 107
- Citations by year
- 2026: 3 · 2025: 16 · 2024: 19 · 2023: 10 · 2022: 19 · 2021: 14 · 2020: 9 · 2019: 18 · 2018: 9 · 2017: 9 · 2016: 5
- FWCI
- 0.76
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Frontiers in Behavioral Neuroscience (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Funders
- National Institute on Drug Abuse (R01DA031626)
- Division of Cancer Prevention, National Cancer Institute (R01CA152062)
- National Institute of General Medical Sciences (R01GM109996)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Social Sciences › Decision Sciences › General Decision Sciences › Decision-Making and Behavioral Economics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Keywords
- insula, decision-making, outcome measurement, action selection, outcome processing, harm avoidance, self-regulation, dorsal anterior insula, ventral anterior insula, posterior insula
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
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