Complex living conditions impair behavioral inhibition but improve attention in rats.
Open accessAbstract
Rapid adaptation to changes, while maintaining a certain level of behavioral inhibition is an important feature in every day functioning. How environmental context and challenges in life can impact on the development of this quality is still unknown. In the present study, we examined the effect of a complex rearing environment during adolescence on attention and behavioral inhibition in adult male rats. We also tested whether these effects were affected by an adverse early life challenge, maternal deprivation (MD). We found that animals that were raised in large, two floor Marlau(TM) cages, together with 10 conspecifics, showed improved attention, but impaired behavioral inhibition in the 5-choice serial reaction time task. The early life challenge of 24 h MD on postnatal day 3 led to a decline in bodyweight during adolescence, but did not by itself influence responses in the 5-choice task in adulthood, nor did it moderate the effects of complex housing. Our data suggest that a complex rearing environment leads to a faster adaptation to changes in the environment, but at the cost of lower behavioral inhibition.
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Complex housing increases attention but diminishes behavioral inhibition.
“We have previously found complex housing to increase attention, but diminish behavioral inhibition (van der Veen et al., 2015).”
From Effects of Maternal Deprivation and Complex Housing on Rat Social Behavior in Adolescence and Adulthood (2018) · cites this paper as van der Veen et al., 2015
Maternally deprived animals showed a lower body weight in adolescence.
“Consistent with previous studies (Marco et al., 2015; van der Veen et al., 2015; Kentrop et al., 2016), maternally deprived animals showed a lower body weight in adolescence.”
From Effects of Maternal Deprivation and Complex Housing on Rat Social Behavior in Adolescence and Adulthood (2018) · cites this paper as van der Veen et al., 2015
Complex housed rats habituate faster to novel situations.
“Previously we and others have shown that complex housed rats habituate faster to novel situations (Zimmermann et al., 2001; Moncek et al., 2004; van der Veen et al., 2015)”
From Effects of Maternal Deprivation and Complex Housing on Rat Social Behavior in Adolescence and Adulthood (2018) · cites this paper as van der Veen et al., 2015
Complex housed animals appear to quickly integrate a novel environment.
“In general, complex housed animals appear to quickly integrate a novel environment (van der Veen et al., 2015)”
From Effects of Maternal Deprivation and Complex Housing on Rat Social Behavior in Adolescence and Adulthood (2018) · cites this paper as van der Veen et al., 2015
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Kentrop, J., Smid, C. R., Achterberg, E. J. M., van IJzendoorn, M. H., Bakermans-Kranenburg, M. J., Joëls, M., & van der Veen, R. (2018) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2018.00193 · Cited by 41 · see citing works
Self-citationKentrop, J., van der Tas, L., Loi, M., van IJzendoorn, M. H., Bakermans-Kranenburg, M. J., Joëls, M., & van der Veen, R. (2016) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2016.00122 · Cited by 16 · see citing works
Self-citation
- Authors
- van der Veen, R., Kentrop, J., van der Tas, L., Loi, M., van IJzendoorn, M. H., Bakermans-Kranenburg, M. J., & Joëls, M.
- Affiliations
- University Medical Center Utrecht (NL)
- Venue
- Frontiers in Behavioral Neuroscience
- Publisher
- Frontiers Media SA
- Published
- 2015-12-24
- Volume
- 9
- Pages
- 357-357
- ISSN
- 1662-5153 (ISSN-L)
- PMC
- PMC4689791
- OpenAlex
- W2224839333
- Cited by
- 14
- References
- 7
- Citations by year
- 2026: 1 · 2023: 1 · 2022: 3 · 2021: 3 · 2020: 4 · 2018: 1 · 2016: 1
- FWCI
- 0.40
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- cc-by
- Locations
- Frontiers in Behavioral Neuroscience (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Leiden Repository (Leiden University) (submittedVersion)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Utrecht University Repository (Utrecht University) (submittedVersion, other-oa)
- Data Archiving and Networked Services (DANS) (submittedVersion)
- Funders
- Gravitation program of the Dutch Ministry of Education, Culture, and Science and the Netherlands Organization for Scientific Research (NWO grant number 024.001.003)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Memory and Neural Mechanisms
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural and Behavioral Psychology Studies
- Life Sciences › Neuroscience › Behavioral Neuroscience › Stress Responses and Cortisol
- Keywords
- behavioral inhibition, attention, maternal deprivation, childhood adversity, adolescence, residential environment, 5-choice serial reaction time task, rats, environmental enrichment, adaptation to change
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