Microglia, seen from the CX3CR1 angle

Resting microglial cells are highly dynamic surveillants of brain parenchyma in vivo

Nimmerjahn, A., Kirchhoff, F., & Helmchen, F. (2005) · Science · doi:10.1126/science.1110647 · Cited by 5,827

Fate Mapping Analysis Reveals That Adult Microglia Derive from Primitive Macrophages

Ginhoux, F., Greter, M., Leboeuf, M., Nandi, S., See, P., Gokhan, S., Mehler, M. F., Conway, S. J., Ng, L. G., Stanley, E. R., et al. (2010) · Science · doi:10.1126/science.1194637 · Cited by 5,175

Synaptic Pruning by Microglia Is Necessary for Normal Brain Development

Paolicelli, R. C., Bolasco, G., Pagani, F., Maggi, L., Scianni, M., Panzanelli, P., Giustetto, M., Ferreira, T. A., Guiducci, E., Dumas, L., et al. (2011) · Science · doi:10.1126/science.1202529 · Cited by 4,244

Microglia Sculpt Postnatal Neural Circuits in an Activity and Complement-Dependent Manner

Schafer, D. P., Lehrman, E. K., Kautzman, A. G., Koyama, R., Mardinly, A. R., Yamasaki, R., Ransohoff, R. M., Greenberg, M. E., Barres, B. A., & Stevens, B. (2012) · Neuron · doi:10.1016/j.neuron.2012.03.026 · Cited by 4,089

ATP mediates rapid microglial response to local brain injury in vivo

Davalos, D., Grutzendler, J., Yang, G., Kim, J. V., Zuo, Y., Jung, S., Littman, D. R., Dustin, M. L., & Gan, W.-B. (2005) · Nature Neuroscience · doi:10.1038/nn1472 · Cited by 3,913

Microglia: Active sensor and versatile effector cells in the normal and pathologic brain

Hanisch, U.-K., & Kettenmann, H. (2007) · Nature Neuroscience · doi:10.1038/nn1997 · Cited by 3,676

Fate Mapping Reveals Origins and Dynamics of Monocytes and Tissue Macrophages under Homeostasis

Yona, S., Kim, K.-W., Wolf, Y., Mildner, A., Varol, D., Breker, M., Strauss-Ayali, D., Viukov, S., Guilliams, M., Misharin, A., et al. (2013) · Immunity · doi:10.1016/j.immuni.2012.12.001 · Cited by 3,245

Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus

Srinivas, S., Watanabe, T., Lin, C.-S., William, C. M., Tanabe, Y., Jessell, T. M., & Costantini, F. (2001) · BMC Developmental Biology · doi:10.1186/1471-213x-1-4 · Cited by 3,121

Development of Monocytes, Macrophages, and Dendritic Cells

Geissmann, F., Manz, M. G., Jung, S., Sieweke, M. H., Merad, M., & Ley, K. (2010) · Science · doi:10.1126/science.1178331 · Cited by 3,049

Analysis of Fractalkine Receptor CX3CR1 Function by Targeted Deletion and Green Fluorescent Protein Reporter Gene Insertion

Jung, S., Aliberti, J., Graemmel, P., Sunshine, M. J., Kreutzberg, G. W., Sher, A., & Littman, D. R. (2000) · Molecular and Cellular Biology · doi:10.1128/mcb.20.11.4106-4114.2000 · Cited by 2,632

PET Imaging Radiotracers of Chemokine Receptors

Alluri, S. R., Higashi, Y., & Kil, K.-E. (2021) · Molecules · doi:10.3390/molecules26175174 · Cited by 17

Ovariectomy in mice primes hippocampal microglia to exacerbate behavioral sickness responses

Sanchez, K. G., Wu, S. L., Kakkar, R., Darling, J. S., Harper, C., & Fonken, L. K. (2023) · Brain Behavior & Immunity - Health · doi:10.1016/j.bbih.2023.100638 · Cited by 16

Contribution of macrophages to neural survival and intracochlear tissue remodeling responses following cochlear implantation

Rahman, M. T., Mostaert, B. J., Hunger, B., Saha, U., Claussen, A. D., Razu, I., Nasrin, F., Khan, N. A., Eckard, P., Coleman, S., et al. (2023) · Journal of Neuroinflammation · doi:10.1186/s12974-023-02955-y · Cited by 16

A Combination of Ex vivo Diffusion MRI and Multiphoton to Study Microglia/Monocytes Alterations after Spinal Cord Injury

Noristani, H. N., Boukhaddaoui, H., Saint-Martin, G., Auzer, P., Sidi‐Boulenouar, R., Lonjon, N., Alibert, É., Tricaud, N., Goze‐Bac, C., Coillot, C., et al. (2017) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2017.00230 · Cited by 16

Distinct spatiotemporal features of microglia and monocyte‐derived macrophages in glioma

Banerjee, K., Ratzabi, A., Caspit, I. M., Ganon, O., Blinder, P., Jung, S., & Stein, R. (2023) · European Journal of Immunology · doi:10.1002/eji.202250161 · Cited by 15

Mind the Gap: Unraveling the Intricate Dance Between Alzheimer’s Disease and Related Dementias and Bone Health

Karnik, S. J., Margetts, T. J., Wang, H. S., Movilă, A., Oblak, A. L., Fehrenbacher, J. C., Kacena, M. A., & Plotkin, L. I. (2024) · Current Osteoporosis Reports · doi:10.1007/s11914-023-00847-x · Cited by 15

A role for macrophages in hematopoiesis in the embryonic head

Li, Z., Mariani, S. A., Rodríguez‐Seoane, C., He, W., Ning, X., Liu, B., Vink, C. S., & Dzierzak, E. A. (2019) · Blood · doi:10.1182/blood.2018881243 · Cited by 14

Temporal changes in the microglial proteome of male and female mice after a diffuse brain injury using label‐free quantitative proteomics

Doust, Y. V., Bindoff, A. D., Holloway, O. G., Wilson, R., King, A. E., & Ziebell, J. M. (2022) · Glia · doi:10.1002/glia.24313 · Cited by 14

Transplanting Microglia for Treating CNS Injuries and Neurological Diseases and Disorders, and Prospects for Generating Exogenic Microglia

Var, S. R., Strell, P., Johnson, S. T., Roman, A., Vasilakos, Z., & Low, W. C. (2023) · Cell Transplantation · doi:10.1177/09636897231171001 · Cited by 15

Inhibition of MALT1 Decreases Neuroinflammation and Pathogenicity of Virulent Rabies Virus in Mice

Kip, E., Staal, J., Tima, H. G., Verstrepen, L., Romano, M., Lemeire, K., Suin, V., Hamouda, A., Baens, M., Libert, C., et al. (2018) · Journal of Virology · doi:10.1128/jvi.00720-18 · Cited by 13

Usage of Multiparameter Flow Cytometry to Study Microglia and Macrophage Heterogeneity in the Central Nervous System During Neuroinflammation and Neurodegeneration

Dukhinova, M., Kopeikina, E., & Ponomarev, E. D. (2018) · Methods in molecular biology · doi:10.1007/978-1-4939-7680-5_10 · Cited by 12

In Vitro Model to Investigate Communication between Dorsal Root Ganglion and Spinal Cord Glia

Ma, J., Patil, V., Pandit, A. S., Quinlan, L. R., Finn, D. P., Grad, S., Alini, M., & Peroglio, M. (2021) · International Journal of Molecular Sciences · doi:10.3390/ijms22189725 · Cited by 12

Shedding light on the role of CX3CR1 in the pathogenesis of schizophrenia

Chamera, K., Szuster-Głuszczak, M., & Basta‐Kaim, A. (2021) · Pharmacological Reports · doi:10.1007/s43440-021-00269-5 · Cited by 12

Microglia at the Centre of Brain Research: Accomplishments and Challenges for the Future

Soares, N. L., & Vieira, H. L. A. (2021) · Neurochemical Research · doi:10.1007/s11064-021-03456-1 · Cited by 14

Adrenoceptors as Potential Target for Add-On Immunomodulatory Therapy in Multiple Sclerosis

Pilipović, I., Stojić-Vukanić, Z., & Leposavić, G. (2022) · Pharmacology & Therapeutics · doi:10.1016/j.pharmthera.2023.108358 · Cited by 11

Microglial LRRK2 ‐mediated NFATc1 attenuates α‐synuclein immunotoxicity in association with CX3CR1 ‐induced migration and the lysosome‐initiated degradation

Feng, L., Lo, H., Hong, Z., Zheng, J., Yan, Y., Ye, Z., Chen, X., & Pan, X. (2023) · Glia · doi:10.1002/glia.24422 · Cited by 12

RasV12 Expression in Microglia Initiates Retinal Inflammation and Induces Photoreceptor Degeneration

Moriuchi, Y., Iwagawa, T., Tsuhako, A., Koso, H., Fujita, Y., & Watanabe, S. (2020) · Investigative Ophthalmology & Visual Science · doi:10.1167/iovs.61.13.34 · Cited by 11

The Role of PDE11A4 in Social Isolation-Induced Changes in Intracellular Signaling and Neuroinflammation

Pilarzyk, K., Farmer, R., Porcher, L., & Kelly, M. P. (2021) · Frontiers in Pharmacology · doi:10.3389/fphar.2021.749628 · Cited by 9

Cellules microgliales et développement du système nerveux central chez l’embryon

Legendre, P., & Corronc, H. L. (2014) · médecine/sciences · doi:10.1051/medsci/20143002011 · Cited by 12

Neuroinflammation in liver disease: sessional talks from ISHEN

Wright, G. A. K., Swain, M. G., Annane, D., Saliba, F., Samuel, D., Arroyo, V., DeMorrow, S., & Witt, A. M. (2016) · Metabolic Brain Disease · doi:10.1007/s11011-016-9918-7 · Cited by 8

Emerging evidence of context-dependent synapse elimination by phagocytes in the CNS

Shen, F.-S., Liu, C., Sun, H.-Z., Chen, X., Xue, Y., & Chen, L. (2024) · Journal of Leukocyte Biology · doi:10.1093/jleuko/qiae098 · Cited by 8

Bujing Yishi tablets alleviate photoreceptor cells death via the P2X7R/CX3CL1/CX3CR1 pathway in Retinitis Pigmentosa rats

Qi, Y., Liu, L., Liang, D., Tang, S., Yu, X., Ye, H., & Chen, N. (2023) · Phytomedicine · doi:10.1016/j.phymed.2023.154828 · Cited by 7

Microglial histone deacetylase 2 is dispensable for functional and histological outcomes in a mouse model of traumatic brain injury

Zhang, Y., Zhao, Y., Wang, Y., Li, J., Huang, Y., Lyu, F., Wang, Y., Wei, P., Yuan, Y., Fu, Y., et al. (2023) · Journal of Cerebral Blood Flow & Metabolism · doi:10.1177/0271678x231197173 · Cited by 7

Application of a pharmacological transcriptome filter identifies a shortlist of mouse glucocorticoid receptor target genes associated with memory consolidation

Buurstede, J. C., Umeoka, E. H. D. L., da Silva, M. S., Krugers, H. J., Joëls, M., & Meijer, O. C. (2022) · Neuropharmacology · doi:10.1016/j.neuropharm.2022.109186 · Cited by 8

Tracing bone marrow-derived microglia in brain metastatic tumors

Du, W., & Bos, P. D. (2020) · Methods in enzymology on CD-ROM/Methods in enzymology · doi:10.1016/bs.mie.2019.08.017 · Cited by 7

Tracking distinct microglia subpopulations with photoconvertible Dendra2 in vivo

Miller, E. B., Karlen, S. J., Ronning, K. E., & Burns, M. E. (2021) · Journal of Neuroinflammation · doi:10.1186/s12974-021-02285-x · Cited by 7

Unravelling the Neuroinflammatory Mechanisms Underlying the Effects of Social Defeat Stress on Use of Drugs of Abuse

Montagud‐Romero, S., Miñarro, J., & Rodríguez‐Arias, M. (2021) · Current topics in behavioral neurosciences · doi:10.1007/7854_2021_260 · Cited by 7

Haploinsufficiency at the CX3CR1 locus of hematopoietic stem cells favors the appearance of microglia-like cells in the central nervous system of transplant recipients

Montepeloso, A., Mattioli, D., Pellin, D., Peviani, M., Genovese, P., & Biffi, A. (2024) · Nature Communications · doi:10.1038/s41467-024-54515-4 · Cited by 6

Unraveling the complexity of microglial responses in traumatic brain and spinal cord injury

Henry, R. J., & Loane, D. J. (2025) · Handbook of clinical neurology · doi:10.1016/b978-0-443-19102-2.00015-6 · Cited by 7

Electrophysiological Investigation of Microglia

Avignone, E., Milior, G., Arnoux, I., & Audinat, É. (2019) · Methods in molecular biology · doi:10.1007/978-1-4939-9658-2_9 · Cited by 6

Macrophage regulation of the “second brain”: CD163 intestinal macrophages interact with inhibitory interneurons to regulate colonic motility - evidence from the Cx3cr1-Dtr rat model

Yip, J. L. K., Xavier, S., Balasuriya, G. K., Hill‐Yardin, E. L., & Spencer, S. J. (2023) · Frontiers in Immunology · doi:10.3389/fimmu.2023.1269890 · Cited by 6

Chronic Alcoholism and HHV-6 Infection Synergistically Promote Neuroinflammatory Microglial Phenotypes in the Substantia Nigra of the Adult Human Brain

Jain, N., Smirnovs, M., Strojeva, S., Murovska, M., & Skuja, S. (2021) · Biomedicines · doi:10.3390/biomedicines9091216 · Cited by 6

The role of monocytes in optic nerve injury

Lee, R., Liu, X., Liu, Y., & Khodeiry, M. (2022) · Neural Regeneration Research · doi:10.4103/1673-5374.363825 · Cited by 6

AAV-BDNF gene therapy ameliorates a hypothalamic neuroinflammatory signature in the Magel2-null model of Prader-Willi syndrome

Queen, N. J., Huang, W., Zou, X., Mo, X. M., & Cao, L. (2023) · Molecular Therapy — Methods & Clinical Development · doi:10.1016/j.omtm.2023.09.004 · Cited by 7

Data-driven discovery of mid-pregnancy immune markers associated with maternal lifetime stress: results from an urban pre-birth cohort

Cowell, W., Colicino, E., Lee, A., Enlow, M. B., Flom, J. D., Berin, M. C., Wright, R. O., & Wright, R. J. (2019) · Stress · doi:10.1080/10253890.2019.1686612 · Cited by 6

A unique subtype of ramified microglia associated with synapses in the rat hippocampus

Ohgomori, T., Iinuma, K., Yamada, J., & Jinno, S. (2021) · European Journal of Neuroscience · doi:10.1111/ejn.15330 · Cited by 6

The central nervous system’s proteogenomic and spatial imprint upon systemic viral infections with SARS-CoV-2Preprint

Radke, J., Meinhardt, J., Aschman, T., Chua, R. L., Farztdinov, V. M., Lukkassen, S., Ten, F. W., Friebel, E., Ishaque, N., Franz, J., et al. (2023) · medRxiv · doi:10.1101/2023.01.16.22283804 · Cited by 6

SARS-CoV-2 vaccination during pregnancy enhances offspring hippocampal neurogenesis and working memory via IFN-γ–responsive microglia

Tang, J., Qi, F., Zou, J., Liu, H., Zuo, Z., Wang, L., Wang, N., Li, Z., Kumar, A., Guo, K., et al. (2025) · Communications Biology · doi:10.1038/s42003-025-08691-8 · Cited by 6

CX3CR1: a potential microglia-specific PET imaging target in Alzheimer’s and Parkinson’s diseases

Yang, H., Wang, Y., Xu, Y., & Wang, C. (2025) · Frontiers in Pharmacology · doi:10.3389/fphar.2025.1678159 · Cited by 6

Glial adaptations to high-fat diet in the mediobasal hypothalamus and effects on metabolic control

Batista, K. N. I., Bouchat, A., & Foll, C. L. (2025) · Physiology & Behavior · doi:10.1016/j.physbeh.2025.115017 · Cited by 6

β-Adrenoceptor Blockade Moderates Neuroinflammation in Male and Female EAE Rats and Abrogates Sexual Dimorphisms in the Major Neuroinflammatory Pathways by Being More Efficient in Males

Pilipović, I., Stojić-Vukanić, Z., Prijić, I., Jasnic, N. I., Djordjevic, J. D., & Leposavić, G. (2022) · Cellular and Molecular Neurobiology · doi:10.1007/s10571-022-01246-z · Cited by 5

Hiding in plain sight: Do recruited dendritic cells surround amyloid plaques in Alzheimer’s disease?

Nelson, R. B., Rose, K. N., Menniti, F. S., & Zorn, S. H. (2024) · Biochemical Pharmacology · doi:10.1016/j.bcp.2024.116258 · Cited by 5

Decreased neuronal and increased endothelial fractalkine expression are associated with neuroinflammation in Parkinson’s disease and related disorders

Chu, Y., Harms, A. S., Boehringer, A. V., & Kordower, J. H. (2025) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2025.1557645 · Cited by 5

Advances in Intravital Non-Linear Optical Imaging of the Central Nervous System in Rodents

Rougon, G. N., Brasselet, S., & Debarbieux, F. C. (2016) · Brain Plasticity · doi:10.3233/bpl-160028 · Cited by 5

The Role of Spinal Cord CX3CL1/CX3CR1 Signalling in Chronic Pain

Montague-Cardoso, K., Mrózková, P., & Malcangio, M. (2020) · Current Tissue Microenvironment Reports · doi:10.1007/s43152-020-00006-9 · Cited by 5

Polymerization of misfolded Z alpha-1 antitrypsin protein lowers CX3CR1 expression in human PBMCs

Tumpara, S., Ballmaier, M., Wrenger, S., König, M., Lehmann, M., Lichtinghagen, R., Martínez–Delgado, B., Korenbaum, E., DeLuca, D. S., Jedicke, N., et al. (2021) · eLife · doi:10.7554/elife.64881 · Cited by 5

Single-cell RNA-seq reveals that glioblastoma recapitulates normal brain developmentPreprint

Couturier, C., Ayyadhury, S., Le, P. U., Monlong, J., Riva, G., Allache, R., Baig, S., Yan, X., Bourgey, M., Lee, C., et al. (2018) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/449439 · Cited by 5

Semi-supervised Omics Factor Analysis (SOFA) disentangles known and latent sources of variation in multi-omic dataPreprint

Capraz, T., Vöhringer, H. S., Serrano, K. S. A. K., Flores, R. O. R., Sáez-Rodríguez, J., & Huber, W. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.10.10.617527 · Cited by 5

Smoothened-mediated signaling contributes to immune and non-immune functions of microglia

Mesaoudi, A. E., Kassoussi, A., Zahaf, A., Ayadi, M., Naglieri, S., Marie, C., Encha‐Razavi, F., Bobé, P., Martinovic, J., Parras, C. M., et al. (2025) · Brain Behavior and Immunity · doi:10.1016/j.bbi.2025.106226 · Cited by 4

Never-resting microglia: physiological roles in the healthy brain and pathological implications

(2015) · Frontiers research topics · doi:10.3389/978-2-88919-369-1 · Cited by 4

The CD40/CD40 ligand dyad and its downstream effector molecule ISG54 in relating acute neuroinflammation with persistent, progressive demyelination

Hazra, B., & Sarma, J. D. (2023) · IUBMB Life · doi:10.1002/iub.2798 · Cited by 4

An easy to use tool for the analysis of subcellular mRNA transcript colocalisation in smFISH data

Bentley-Abbot, C., Heslop, R., Pirillo, C., Chandrasegaran, P. R. G., McConnell, G., Roberts, E., Hutchinson, E. C., & MacLeod, A. (2024) · Scientific Reports · doi:10.1038/s41598-024-58641-3 · Cited by 4

Single Cell Scale Neuronal and Glial Gene Expression and Putative Cell Phenotypes and Networks in the Nucleus Tractus Solitarius in an Alcohol Withdrawal Time Series

O’Sullivan, S. J., McIntosh-Clarke, D., Park, J. S., Vadigepalli, R., & Schwaber, J. S. (2021) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2021.739790 · Cited by 4

Cx3cr1CreERT2-driven Atg7 deletion in adult mice induces intestinal adhesion

Lee, Y., Lee, J., Nam, H., & Yu, S. (2020) · Molecular Brain · doi:10.1186/s13041-020-00630-4 · Cited by 4

Emerging Techniques for the Study of Microglia: Visualization, Depletion and Fate MappingPreprint

Bobotis, B. C., Halvorson, T., Carrier, M., & Tremblay, M. (2023) · Preprints.org · doi:10.20944/preprints202308.2190.v1 · Cited by 3

Focusing on microglial mitochondria-lysosome crosstalk and neuroinflammation underlying depression: from molecular pathways to potential therapeutic interventions

Zou, X., Shi, M., Xiao, X., Lv, X., Yang, M., Tian, M., Xie, B., Wang, L., Wang, J., & Qin, D. (2026) · Frontiers in Immunology · doi:10.3389/fimmu.2026.1775841 · Cited by 4

Neuroglia in epilepsy

Ghouli, M. R., & Binder, D. K. (2025) · Handbook of clinical neurology · doi:10.1016/b978-0-443-19102-2.00016-8 · Cited by 3

Single nucleus RNA sequencing unveils relationship between microglia and endothelial cells in mixed Alzheimer's disease and vascular pathology

Olayinka, O. A., O’Neill, N. K., Empawi, J. A., Bock, P., Hu, J., Rickner, H., Wong, M., Stein, T. D., Wolozin, B. L., Farrer, L. A., et al. (2025) · Neurobiology of Disease · doi:10.1016/j.nbd.2025.107128 · Cited by 5

Lytic Cell Death in Specific Microglial Subsets Is Required for Preventing Atypical Behavior in Mice

Chuang, H.-C., Nichols, E. K., Rauch, I., Chang, W.-C., Misra, R., Lin, P. M., Kitaoka, M., Vance, R. E., & Saijo, K. (2021) · eNeuro · doi:10.1523/eneuro.0342-20.2020 · Cited by 3

Succinum extracts inhibit microglial-derived neuroinflammation and depressive-like behaviors

Kang, J.-Y., Baek, D.-C., Son, C., & Lee, J. (2022) · Frontiers in Pharmacology · doi:10.3389/fphar.2022.991243 · Cited by 3

Neuroprotection Versus Neurotoxicity

Biber, K. P. H., & Block, M. L. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1429-6_6 · Cited by 3

Single Neuronal and Glial Gene Expression in the Nucleus Tractus Solitarius in an Alcohol Withdrawal Time Series Reveals Novel Cellular Phenotypes and NetworksPreprint

O’Sullivan, S. J., McIntosh-Clarke, D., Park, J. S., Vadigepalli, R., & Schwaber, J. S. (2021) · Research Square · doi:10.21203/rs.3.rs-452767/v1 · Cited by 3

Sex-dependent interferon signaling contributes to female-biased vulnerability in Alzheimer’s disease

López-López, V., Iniesta, G., Galán-Ganga, M., Exposito-Coca, A., Durán-Laforet, V., Bhojwani-Cabrera, A. M., Navarrón, C. M., Guillot-Fernández, M., Venero, J. L., Sanchez-Mut, J. V., et al. (2026) · Journal of Neuroinflammation · doi:10.1186/s12974-026-03840-0 · Cited by 4

Prenatal-induced psychopathologies: All roads lead to microglia

Lebow, M., Kuperman, Y., & Chen, A. (2023) · Elsevier eBooks · doi:10.1016/b978-0-12-817558-3.00016-0 · Cited by 2

The Neuroimmune Regulation and Potential Therapeutic Strategies of Optic Pathway Glioma

Irshad, K., Huang, Y.-K., Rodriguez, P., Lo, J., Aghoghovwia, B. E., Pan, Y., & Chang, K. (2023) · Brain Sciences · doi:10.3390/brainsci13101424 · Cited by 2

Modeling Pain Without Injury: Inherited Rodent Models as Mechanistic Windows into Chronic Pain

Ferrari, L. F., & Taylor, N. E. (2025) · Function · doi:10.1093/function/zqaf043 · Cited by 3

Aryl hydrocarbon receptor restrains tonic cytokine responses by inhibiting microbiota sensing in monocytes

Cros, A., Rigamonti, A., de Juan, A., Coillard, A., Rieux-Laucat, M., Tabtim-On, D., Papillon, E., Goudot, C., Cepika, A., Banchereau, R., et al. (2025) · Journal of Clinical Investigation · doi:10.1172/jci189937 · Cited by 2

Adult Neurogenesis, Learning and Memory

Sierra, A., & Tremblay, M. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1429-6_10 · Cited by 3

A Role for Microglia in Retinal Development

Guttenplan, K. A., Blum, J. A., & Bennett, M. L. (2018) · Journal of Neuroscience · doi:10.1523/jneurosci.1813-18.2018 · Cited by 2

Integrative Transcriptomics Reveals Layer 1 Astrocytes Altered in SchizophreniaPreprint

Leon, J., Yoshinaga, S., Hino, M., Nagaoka, A., Ando, Y., Moody, J., Kojima, M., Kitazawa, A., Hayashi, K., Nakajima, K., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.06.27.601103 · Cited by 4

NIK-driven IL-23 production by myeloid cells is a key factor in the development of autoimmune inflammation

Ramphal, N. S., Liu, X., Palagi, I., Jasser, R., Mohebiany, A. N., Klein, M., Westermann, F., Krishnarajah, S., Regen, T., Bopp, T., et al. (2026) · The Journal of Experimental Medicine · doi:10.1084/jem.20242294 · Cited by 1

Neuroinflammation and mononuclear phagocytes in glaucoma: From ocular pathogenesis to central visual pathway involvement — A comprehensive review

Bastelica, P., Reboussin, É., Przegralek, L., Darche, M., Buffault, J., Goazigo, A. R.-L., Labbé, A., Parsadaniantz, S. M., & Baudouin, C. (2026) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2026.119648 · Cited by 1

Development and characterisation of mgTHP-1, a novel in vitro model for neural macrophages with microglial characteristics

Kodosaki, E., Daniels-Morgan, A., Hassan, N., Webb, R., Morris, K., & Kelly, C. (2023) · Neurological Research · doi:10.1080/01616412.2023.2257422 · Cited by 2

Microglial Ontogeny and Functions in Shaping Brain Circuits

Hoeffel, G., Squarzoni, P., Garel, S., & Ginhoux, F. (2014) · Springer eBooks · doi:10.1007/978-1-4939-1311-4_9 · Cited by 1

Contribution of Neuroinflammation in the Pathogenesis of Alzheimer’s Disease

Farooqui, A. A. (2017) · Elsevier eBooks · doi:10.1016/b978-0-12-809937-7.00006-9 · Cited by 1

How Repair-or-Dispose Decisions Under Stress Can Initiate Disease Progression

Nold, A., Batulin, D., Birkner, K., Bittner, S., & Tchumatchenko, T. (2020) · iScience · doi:10.1016/j.isci.2020.101701 · Cited by 1

Chronic stress abnormalize microglial-vascular interaction via AT1R signaling and microglia activation to drive depression-like behaviorsPreprint

Gao, H., Ding, Z., Xu, B., Wu, Y., Zhu, M., Zhang, X., Qi, F., Liu, J., Fang, Q., & Ran, Y. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.24.696453 · Cited by 1

Implication du canal potassium Kv3.1 dans la lipotoxicité du 7-cétocholestérol, 24S-hydroxycholestérol et de l’acide tétracosanoïque sur des cellules nerveuses 158N et BV-2 : Etude des relations entre Kv3.1, homéostasie potassique et métabolisme peroxysomal dans la maladie d’Alzheimer

Bezine, M. (2017) · theses.fr (ABES) · doi:10.70675/a634c389z7b07z4830zb56dzbf7b53a56944 · Cited by 1

Aging

König, R., Rotheneichner, P., Marschallinger, J., Aigner, L., & Couillard‐Després, S. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-801977-1.00007-6

Aging exacerbates myelin disruption and axon injury following demyelination

Michaels, N. J. (2019) · doi:10.11575/prism/36466

Exposure to a single immobilization or lipopolysaccharide challenge increases expression of genes implicated in the development of Alzheimer’s disease in the mice brain cortex

Padová, A., Rokytová, I., Mravec, B., Květňanský, R., & Vargovič, P. (2019) · Endocrine Regulations · doi:10.2478/enr-2019-0012

Defective cell death of distinct microglial subsets contributes to ADHD-like behavior in micePreprint

Chuang, H., Nichols, E. K., Rauch, I., Chang, W.-C., Misra, R., Lin, P. M., Kitaoka, M., Vance, R. E., & Saijo, K. (2019) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/749390

Expression and Function of Kir2.1 and Kv1.3 Channels in Cytokine-induced Activation of Rat and Mouse Microglia: A Tale of Two Rodents

Lam, D. (2017) · TSpace (University of Toronto)

Characterization of microglial Rab7 knockout on amyloid pathology in the 5xFAD mouse model of Alzheimer’s disease

Koch, B. M. E. (2019) · eDiss (Georg-August-Universität Göttingen) · doi:10.53846/goediss-7716

Editorial: Cognitive Dysfunctions in Psychiatric Disorders: Brain-Immune Interaction Mechanisms and Integrative Therapeutic Approaches

Xu, H., Wang, W., Ellenbroek, B. A., & You, Z. (2021) · Frontiers in Integrative Neuroscience · doi:10.3389/fnint.2021.649425

Antibiotic treatment induces activation of microglia and impairment of cholinergic gamma oscillations in the hippocampusPreprint

Çalışkan, G., French, T., Heimesaat, M. M., Dunay, I. R., & Stork, O. (2021) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2021.07.30.454300

RasV12 Expression in Microglia Promotes Retinal Inflammatory Circuits and Impairment of PhotoreceptorPreprint

Moriuchi, Y. W., Iwagawa, T., Tsuhako, A., Koso, H., Fujita, Y., & Watanabe, S. (2020) · doi:10.21203/rs.3.rs-29744/v1

Neurochemical Aspects of Traumatic Brain Injury

Farooqui, A. A. (2018) · Elsevier eBooks · doi:10.1016/b978-0-12-813596-9.00006-7 · Cited by 1

A role for LRRK2 and Neuroinflammatory Processes in Multi-Hit Toxicant Models of Parkinson’s Disease

Rudyk, C. (2018) · doi:10.22215/etd/2018-14444

FISHtoFigure: An easy-to-use tool for rapid, multi-target partitioning and analysis of sub-cellular mRNA transcripts in smFISH dataPreprint

Bentley-Abbot, C., Heslop, R., Pirillo, C., Sinton, M. C., Chandrasegaran, P. R. G., McConnell, G., Roberts, E., Hutchinson, E. C., & MacLeod, A. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.06.28.546871

SARS-CoV-2 vaccination during pregnancy enhances hippocampal neurogenesis and working memory in offspring through IFN-gamma and CX3CR1-dependent mechanismsPreprint

Qi, F., & Yao, Z. (2024) · Research Square · doi:10.21203/rs.3.rs-3831042/v1

SARS-CoV-2 vaccination during pregnancy enhances hippocampal neurogenesis and working memory in offspring via IFN-gamma responsive microgliaPreprint

Liu, F., Tang, J., Zou, J., Liu, H., Zuo, Z., Wang, L., Wang, N., Li, Z., Kumar, A., Guo, K., et al. (2024) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2024.07.03.601972

Phenotype and function of macrophages is regulated by chemokines

Krulová, M., Somova, V., & Fikarová, N. (2024) · Elsevier eBooks · doi:10.1016/b978-0-12-821754-2.00003-5

Semi-supervised Omics Factor Analysis (SOFA) disentangles known and latent sources of variation in multi-omic data

Capraz, T., Vöhringer, H. S., Serrano, K. S. K., Flores, R. O. R., Sáez-Rodríguez, J., & Huber, W. (2026) · Nature Communications · doi:10.1038/s41467-026-74694-6

Infection of 5xFAD mice with a mouse-adapted SARS-CoV-2 does not alter Alzheimer’s disease neuropathology yet induces wide-spread changes in gene expression across diverse cell typesPreprint

Furman, S., Zayou, L., Tsourmas, K. I., Javonillo, D. I., Olivarria, G. M., Cheng, Y., Pachow, C., Fernandez, K., Le, L., Edwards, R. A., et al. (2025) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.64898/2025.12.19.695600

Microglia-Astrocyte Crosstalk Regulates Synapse Remodeling via Wnt Signaling

Li, X., Bai, X., Wang, H., & Ouyang, H. (2026) · Neuropharmacology and Therapy · doi:10.15212/npt-2025-0017

Primitive macrophages regulate the development of dorsal root ganglia sensory neurons in mouse embryos

Angelim, M. K. S. C. (2017) · theses.fr (ABES) · doi:10.70675/2f402166z8a8bz4e47z93c4z20ae8f982074

Peptides vipérins à activité anti-intégrines : intérêt dans le traitement des pathologies ischémiques de la rétine et les DMLA

Montassar, F. (2017) · theses.fr (ABES) · doi:10.70675/7388b1ddz3be3z4d16z935ezddf935ec3ae2

In vitro and in vivo study of the effects of Levetiracetam on activated microglia during sepsis

Fleurance, R. (2021) · theses.fr (ABES) · doi:10.70675/0a82ed6ez6595z4366z832fz70cbe839c7ff

Microglial dynamics in physiological conditions : a vigilance state and neuronal activity-driven mechanism

Hristovska, I. (2019) · theses.fr (ABES) · doi:10.70675/af1c5105z3e0dz43ffzb906z1553e7a23a6e

Reviewed by:

Wolf, Y., Yona, S., Kim, K.-W., Jung, S., Legendre, P., Pierre, U., Université, M.-E. T., Department Of, Kim, K.-W., & Department Of (2013)

Role of CX3CL1 in Synaptic Activity and Neuroprotection

Ragozzino, D., Lauro, C., & Limatola, C. (2009) · Springer eBooks · doi:10.1007/978-1-4419-0793-6_13 · Cited by 1

Chemokine CX3C motif receptor 1 ( CX3CR1 ) promoter–dependent gene expression in microglia

(2013) · Science-Business eXchange · doi:10.1038/scibx.2013.1170

The effect of CX3CL1/ CX3CR1 signal axis on microglia in central nervous system diseases

Zhao, J., Li, Q., Ouyang, X., Wang, F., Li, Q., Xu, Z., Ji, D., Wu, Q., Zhang, J., Lu, C., et al. (2023) · Journal of Neurorestoratology · doi:10.1016/j.jnrt.2023.100042 · Cited by 29

Role for Neuronally Derived Fractalkine in Mediating Interactions between Neurons and CX3CR1-Expressing Microglia

Harrison, J. K., Jiang, Y., Chen, S., Xia, Y., Maciejewski, D., McNamara, R. K., Streit, W. J., Salafranca, M. N., Adhikari, S., Thompson, D. A., et al. (1998) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.95.18.10896 · Cited by 1,176