Region Specific Up-Regulation of Oxytocin Receptors in the Opioid Oprm1−/− Mouse Model of Autism

Diagnostic and Statistical Manual of Mental Disorders

American Psychiatric Association (2013) · doi:10.1176/appi.books.9780890425596 · Cited by 116,369 · see citing works

Diagnostic and Statistical Manual of Mental Disorders

Williams, J. B. W., & First, M. B. (2013) · Oxford University Press eBooks · doi:10.1093/acrefore/9780199975839.013.104 · Cited by 109,841 · see citing works

The mouse brain in stereotaxic coordinates

Konsman, J. (2003) · Psychoneuroendocrinology · doi:10.1016/s0306-4530(03)00088-x · Cited by 16,796 · see citing works

Diagnostic and Statistical Manual of Mental Disorders, 5th ed.

Carter, M. J. (2014) · Therapeutic Recreation Journal · Cited by 15,154 · see citing works

The Mouse Brain in Stereotaxic Coordinates

Paxinos, G. (2001) · Cited by 12,859 · see citing works

Untitled work

(1943) · The Nervous child · Cited by 8,870 · see citing works

Does the autistic child have a “theory of mind” ?

Baron-Cohen, S., Leslie, A. M., & Frith, U. (1985) · Cognition · doi:10.1016/0010-0277(85)90022-8 · Cited by 8,599 · see citing works

Theory of mind

Frith, C., & Frith, U. (2005) · Current Biology · doi:10.1016/j.cub.2005.08.041 · Cited by 3,494 · see citing works

Autistic disturbances of affective contact.

Kanner, L. (1968) · PubMed · Cited by 2,273 · see citing works

The social motivation theory of autism

Chevallier, C., Kohls, G., Troiani, V., Brodkin, E. S., & Schultz, R. T. (2012) · Trends in Cognitive Sciences · doi:10.1016/j.tics.2012.02.007 · Cited by 2,072 · see citing works

Loss of morphine-induced analgesia, reward effect and withdrawal symptoms in mice lacking the μ-opioid-receptor gene

Matthes, H. W. D., Maldonado, R., Simonin, F., Valverde, O., Slowe, S., Kitchen, I., Befort, K., Dierich, A., Le Meur, M., Dollé, P., et al. (1996) · Nature · doi:10.1038/383819a0 · Cited by 1,722 · see citing works

The amygdala and reward

Baxter, M. G., & Murray, E. A. (2002) · Nature Reviews Neuroscience · doi:10.1038/nrn875 · Cited by 1,200 · see citing works

The Medial Extended Amygdala in Male Reproductive Behavior A Node in the Mammalian Social Behavior Network

NEWMAN, S. W. (1999) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1999.tb09271.x · Cited by 1,189 · see citing works

Social reward requires coordinated activity of nucleus accumbens oxytocin and serotonin

Dölen, G., Darvishzadeh, A., Huang, K. W., & Malenka, R. C. (2013) · Nature · doi:10.1038/nature12518 · Cited by 1,161 · see citing works

Oxytocin in the Medial Amygdala is Essential for Social Recognition in the Mouse

Ferguson, J. N., Aldag, J. M., Insel, T. R., & Young, L. J. (2001) · The Journal of Neuroscience · doi:10.1523/jneurosci.21-20-08278.2001 · Cited by 1,043 · see citing works

Oxytocin: The Great Facilitator of Life

Lee, H.-J., Macbeth, A. H., Pagani, J., & Young, W. S. (2009) · Progress in Neurobiology · doi:10.1016/j.pneurobio.2009.04.001 · Cited by 1,037 · see citing works

Promoting social behavior with oxytocin in high-functioning autism spectrum disorders.

Andari, E., Duhamel, J.-R., Zalla, T., Herbrecht, E., Leboyer, M., & Sirigu, A. (2010) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0910249107 · Cited by 941 · see citing works

Oxytocin receptor distribution reflects social organization in monogamous and polygamous voles

Insel, T. R., & Shapiro, L. E. (1992) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.89.13.5981 · Cited by 833 · see citing works

Oxytocin increases generosity in humans

Zak, P. J., Stanton, A. A., & Ahmadi, S. (2007) · PLoS ONE · doi:10.1371/journal.pone.0001128 · Cited by 831 · see citing works

Social and pragmatic deficits in autism: Cognitive or affective?

Baron‐Cohen, S. (1988) · Journal of Autism and Developmental Disorders · doi:10.1007/bf02212194 · Cited by 737 · see citing works

Brain substrates of infant-mother attachment: contributions of opioids, oxytocin, and norepinephrine.

Nelson, E. E., & Panksepp, J. (1998) · Neuroscience & Biobehavioral Reviews · doi:10.1016/s0149-7634(97)00052-3 · Cited by 688 · see citing works

Parallel-distributed Processing in Olfactory Cortex: New Insights from Morphological and Physiological Analysis of Neuronal Circuitry

Haberly, L. B. (2001) · Chemical Senses · doi:10.1093/chemse/26.5.551 · Cited by 673 · see citing works

Ultrasonic Songs of Male Mice

Holy, T. E., & Guo, Z. (2005) · PLoS Biology · doi:10.1371/journal.pbio.0030386 · Cited by 673 · see citing works

Evidence That Oxytocin Exerts Anxiolytic Effects via Oxytocin Receptor Expressed in Serotonergic Neurons in Mice

Yoshida, M., Takayanagi, Y., Inoue, K., Kimura, T., Young, L. J., Onaka, T., & Nishimori, K. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.5593-08.2009 · Cited by 608 · see citing works

G Protein–Coupled Receptor Oligomerization Revisited: Functional and Pharmacological Perspectives

Ferré, S., Casadó, V., Devi, L. A., Filizola, M., Jockers, R., Lohse, M. J., Milligan, G., Pin, J., & Guitart, X. (2014) · Pharmacological Reviews · doi:10.1124/pr.113.008052 · Cited by 574 · see citing works

Increased brain and plasma oxytocin after nasal and peripheral administration in rats and mice

Neumann, I. D., Maloumby, R., Beiderbeck, D. I., Lukas, M., & Landgraf, R. (2013) · Psychoneuroendocrinology · doi:10.1016/j.psyneuen.2013.03.003 · Cited by 511 · see citing works

Variations in maternal behaviour are associated with differences in oxytocin receptor levels in the rat

Francis, D. D., Champagne, F. C., & Meaney, M. J. (2000) · Journal of Neuroendocrinology · doi:10.1046/j.1365-2826.2000.00599.x · Cited by 496 · see citing works

Oxytocin, vasopressin, and social recognition in mammals

Bielsky, I. F., & Young, L. J. (2004) · Peptides · doi:10.1016/j.peptides.2004.05.019 · Cited by 460 · see citing works

Oxytocin can hinder trust and cooperation in borderline personality disorder

Bartz, J., Simeon, D., Hamilton, H., Kim, S., Crystal, S., Braun, A., Vicens, V., & Hollander, E. (2011) · Social Cognitive and Affective Neuroscience · doi:10.1093/scan/nsq085 · Cited by 452 · see citing works

Deficit in Attachment Behavior in Mice Lacking the µ-Opioid Receptor Gene

Moles, A., Kieffer, B. L., & D'Amato, F. R. (2004) · Science · doi:10.1126/science.1095943 · Cited by 449 · see citing works

Opioid Hedonic Hotspot in Nucleus Accumbens Shell: Mu, Delta, and Kappa Maps for Enhancement of Sweetness “Liking” and “Wanting”

Castro, D. C., & Berridge, K. C. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.4458-13.2014 · Cited by 395 · see citing works

Regulation of Human Affective Responses by Anterior Cingulate and Limbic µ-Opioid Neurotransmission

Zubieta, J., Ketter, T. A., Bueller, J. A., Xu, Y., Kilbourn, M. R., Young, E. A., & Koeppe, R. A. (2003) · Archives of General Psychiatry · doi:10.1001/archpsyc.60.11.1145 · Cited by 377 · see citing works

A neurochemical theory of autism

Panksepp, J. (1979) · Trends in Neurosciences · doi:10.1016/0166-2236(79)90071-7 · Cited by 326 · see citing works

Variation in oxytocin receptor density in the nucleus accumbens has differential effects on affiliative behaviors in monogamous and polygamous voles

Ross, H. E., Freeman, S. M., Spiegel, L. L., Ren, X., Terwilliger, E. F., & Young, L. J. (2009) · The Journal of Neuroscience · doi:10.1523/jneurosci.5039-08.2009 · Cited by 322 · see citing works

The α2aAdrenergic Receptor Subtype Mediates Spinal Analgesia Evoked by α2Agonists and Is Necessary for Spinal Adrenergic–Opioid Synergy

Stone, L. S., MacMillan, L. B., Kitto, K. F., Limbird, L. E., & Wilcox, G. L. (1997) · Journal of Neuroscience · doi:10.1523/jneurosci.17-18-07157.1997 · Cited by 296 · see citing works

The magnocellular oxytocin system, the fount of maternity: Adaptations in pregnancy

Russell, J. A., Leng, G., & Douglas, A. J. (2003) · Frontiers in Neuroendocrinology · doi:10.1016/s0091-3022(02)00104-8 · Cited by 295 · see citing works

Oxytocin receptors in the nucleus accumbens facilitate “spontaneous” maternal behavior in adult female prairie voles

Olazábal, D. E., & Young, L. J. (2006) · Neuroscience · doi:10.1016/j.neuroscience.2006.04.017 · Cited by 289 · see citing works

A mu–delta opioid receptor brain atlas reveals neuronal co-occurrence in subcortical networks

Erbs, E., Faget, L. C., Scherrer, G., Matifas, A., Filliol, D., Vonesch, J., Koch, M., Kessler, P., Hentsch, D., Birling, M., et al. (2014) · Brain Structure and Function · doi:10.1007/s00429-014-0717-9 · Cited by 287 · see citing works

Chronic intranasal oxytocin causes long-term impairments in partner preference formation in male prairie voles

Bales, K. L., Perkeybile, A. M., Conley, O. G., Lee, M. H., Guoynes, C. D., Downing, G. M., Yun, C. R., Solomon, M., Jacob, S., & Mendoza, S. P. (2013) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.08.025 · Cited by 265 · see citing works

Conformational cross-talk between α2A-adrenergic and μ-opioid receptors controls cell signaling

Vilardaga, J., Nikolaev, V. O., Lorenz, K., Ferrandon, S., Zhuang, Z., & Lohse, M. J. (2008) · Nature Chemical Biology · doi:10.1038/nchembio.64 · Cited by 264 · see citing works

Nucleus Accumbens μ-Opioid Receptors Mediate Social Reward

Trezza, V., Damsteegt, R., Achterberg, E. J. M., & Vanderschuren, L. J. M. J. (2011) · The Journal of Neuroscience · doi:10.1523/jneurosci.5492-10.2011 · Cited by 263 · see citing works

Species and individual differences in juvenile female alloparental care are associated with oxytocin receptor density in the striatum and the lateral septum

Olazábal, D. E., & Young, L. J. (2006) · Hormones and Behavior · doi:10.1016/j.yhbeh.2005.12.010 · Cited by 230 · see citing works

Quantitative autoradiographic mapping of μ-, δ- and κ-opioid receptors in knockout mice lacking the μ-opioid receptor gene

Kitchen, I., Slowe, S. J., Matthes, H. W. D., & Kieffer, B. L. (1997) · Brain Research · doi:10.1016/s0006-8993(97)00988-8 · Cited by 229 · see citing works

Response of the μ-opioid system to social rejection and acceptance

Hsu, D. T., Sanford, B. J., Meyers, K. K., Love, T. M., Hazlett, K. E., Wang, H., Ni, L., Walker, S. J., Mickey, B. J., Korycinski, S. T., et al. (2013) · Molecular Psychiatry · doi:10.1038/mp.2013.96 · Cited by 225 · see citing works

A field guide to the anterior olfactory nucleus (cortex)

Brunjes, P. C., Illig, K. R., & Meyer, E. A. (2005) · Brain Research Reviews · doi:10.1016/j.brainresrev.2005.08.005 · Cited by 224 · see citing works

Dopamine, oxytocin, and vasopressin receptor binding in the medial prefrontal cortex of monogamous and promiscuous voles

Smeltzer, M. D., Curtis, J. T., Aragona, B. J., & Wang, Z. (2006) · Neuroscience Letters · doi:10.1016/j.neulet.2005.10.019 · Cited by 222 · see citing works

Drug Addiction, Relapse, and the Amygdala

See, R. E., Fuchs, R. A., Ledford, C. C., & McLaughlin, J. (2003) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.2003.tb07089.x · Cited by 212 · see citing works

A neural switch for active and passive fear

Gozzi, A., Jain, A., Giovanelli, A., Bertollini, C., Crestan, V., Schwarz, A. J., Tsetsenis, T., Ragozzino, D., Gross, C. T., & Bifone, A. (2010) · Neuron · doi:10.1016/j.neuron.2010.07.008 · Cited by 209 · see citing works

Sex differences in oxytocin receptor binding in forebrain regions: correlations with social interest in brain region- and sex-specific ways

Dumais, K. M., Bredewold, R., Mayer, T. E., & Veenema, A. H. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2013.08.012 · Cited by 201 · see citing works

Chronic and acute intranasal oxytocin produce divergent social effects in mice

Huang, H., Michetti, C., Busnelli, M., Managò, F., Sannino, S., Scheggia, D., Giancardo, L., Sona, D., Murino, V., Chini, B., et al. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2013.310 · Cited by 199 · see citing works

Female behavior is affected by male ultrasonic vocalizations in house mice

Pomerantz, S. M., Núñez, A. A., & Bean, N. J. (1983) · Physiology & Behavior · doi:10.1016/0031-9384(83)90101-4 · Cited by 198 · see citing works

Variation at the mu-opioid receptor gene ( <i>OPRM1</i> ) influences attachment behavior in infant primates

Barr, C. S., Schwandt, M. L., Lindell, S. G., Higley, J. D., Maestripieri, D., Goldman, D., Suomi, S. J., & Heilig, M. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0710225105 · Cited by 191 · see citing works

Functional Interactions between μ Opioid and α2A-Adrenergic Receptors

Jordan, B. A., Gomes, I., Rios, C., Filipovska, J., & Devi, L. A. (2003) · Molecular Pharmacology · doi:10.1124/mol.64.6.1317 · Cited by 173 · see citing works

Female Presence and Estrous State Influence Mouse Ultrasonic Courtship Vocalizations

Hanson, J. L., & Hurley, L. M. (2012) · PLoS ONE · doi:10.1371/journal.pone.0040782 · Cited by 161 · see citing works

Increasing oxytocin receptor expression in the nucleus accumbens of pre-pubertal female prairie voles enhances alloparental responsiveness and partner preference formation as adults

Keebaugh, A. C., & Young, L. J. (2011) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.07.018 · Cited by 154 · see citing works

Targeted expression of μ-opioid receptors in a subset of striatal direct-pathway neurons restores opiate reward

Cui, Y., Ostlund, S. B., James, A. S., Park, C. S., Ge, W., Roberts, K. W., Mittal, N., Murphy, N. P., Cepeda, C., Kieffer, B. L., et al. (2014) · Nature Neuroscience · doi:10.1038/nn.3622 · Cited by 147 · see citing works

Long-Term Social Recognition Memory Is Mediated by Oxytocin-Dependent Synaptic Plasticity in the Medial Amygdala

Gur, R., Tendler, A., & Wagner, S. (2014) · Biological Psychiatry · doi:10.1016/j.biopsych.2014.03.022 · Cited by 144 · see citing works

The oxytocin analogue carbetocin prevents emotional impairment and stress-induced reinstatement of opioid-seeking in morphine-abstinent mice

Zanos, P., Georgiou, P., Wright, S. R., Hourani, S. M., Kitchen, I., Winsky-Sommerer, R., & Bailey, A. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2013.285 · Cited by 133 · see citing works

Activation of μ-Opioid Receptors in the Dorsal Striatum is Necessary for Adult Social Attachment in Monogamous Prairie Voles

Burkett, J. P., Spiegel, L. L., Inoue, K., Murphy, A. Z., & Young, L. J. (2011) · Neuropsychopharmacology · doi:10.1038/npp.2011.117 · Cited by 133 · see citing works

Sexually dimorphic expression of oxytocin binding sites in forebrain and spinal cord of the rat

Uhl-Bronner, S., Waltisperger, E., Martínez-Lorenzana, G., Condes Lara, M., & Freund-Mercier, M. J. (2005) · Neuroscience · doi:10.1016/j.neuroscience.2005.05.025 · Cited by 123 · see citing works

Autistic-Like Syndrome in Mu Opioid Receptor Null Mice is Relieved by Facilitated mGluR4 Activity

Becker, J. A. J., Clesse, D., Spiegelhalter, C., Schwab, Y., Merrer, J. L., & Kieffer, B. L. (2014) · Neuropsychopharmacology · doi:10.1038/npp.2014.59 · Cited by 123 · see citing works

Neurobiological correlates of social functioning in autism

Neuhaus, E., Beauchaine, T. P., & Bernier, R. (2010) · Clinical Psychology Review · doi:10.1016/j.cpr.2010.05.007 · Cited by 122 · see citing works

Social hedonic capacity is associated with the A118G polymorphism of the mu-opioid receptor gene (<i>OPRM1</i>) in adult healthy volunteers and psychiatric patients

Troisi, A., Frazzetto, G., Carola, V., Di Lorenzo, G., Coviello, M., D'Amato, F. R., Moles, A., Siracusano, A., & Gross, C. (2011) · Social Neuroscience · doi:10.1080/17470919.2010.482786 · Cited by 118 · see citing works

Oxytocin and Autism: A Systematic Review of Randomized Controlled Trials

Preti, A., Melis, M., Siddi, S., Vellante, M., Doneddu, G., & Fadda, R. (2014) · Journal of Child and Adolescent Psychopharmacology · doi:10.1089/cap.2013.0040 · Cited by 114 · see citing works

Elicitation of male mouse (Mus musculus) ultrasonic vocalizations: I. Urinary cues.

Nyby, J., Wysocki, C. J., Whitney, G., Dizinno, G. A., & Schneider, J. E. (1979) · Journal of Comparative and Physiological Psychology · doi:10.1037/h0077623 · Cited by 110 · see citing works

A mu-opioid receptor single nucleotide polymorphism in rhesus monkey: association with stress response and aggression

Miller, G. M., Bendor, J., Tiefenbacher, S., Yang, H. S., Novak, M. A., & Madras, B. K. (2003) · Molecular Psychiatry · doi:10.1038/sj.mp.4001378 · Cited by 106 · see citing works

μ-Opioid receptors within subregions of the striatum mediate pair bond formation through parallel yet distinct reward mechanisms

Resendez, S. L., Dome, M., Gormley, G., Franco, D., Nevárez, N., Hamid, A. A., & Aragona, B. J. (2013) · The Journal of Neuroscience · doi:10.1523/jneurosci.4123-12.2013 · Cited by 93 · see citing works

Unstable Maternal Environment, Separation Anxiety, and Heightened CO2 Sensitivity Induced by Gene-by-Environment Interplay

D'Amato, F. R., Zanettini, C., Lampis, V., Coccurello, R., Pascucci, T., Ventura, R., Puglisi‐Allegra, S., Spatola, C. A. M., Pesenti‐Gritti, P., Oddi, D., et al. (2011) · PLoS ONE · doi:10.1371/journal.pone.0018637 · Cited by 92 · see citing works

Local oxytocin expression and oxytocin receptor binding in the male rat brain is associated with aggressiveness

Calcagnoli, F., de Boer, S. F., Beiderbeck, D. I., Althaus, M., Koolhaas, J. M., & Neumann, I. D. (2014) · Behavioural Brain Research · doi:10.1016/j.bbr.2013.12.050 · Cited by 84 · see citing works

Neonatal paternal deprivation impairs social recognition and alters levels of oxytocin and estrogen receptor α mRNA expression in the MeA and NAcc, and serum oxytocin in mandarin voles

Cao, Y., Wu, R., Tai, F., Zhang, X., Yu, P., An, X., Qiao, X., & Hao, P. (2013) · Hormones and Behavior · doi:10.1016/j.yhbeh.2013.11.005 · Cited by 82 · see citing works

Opioid modulation of magnocellular neurosecretory cell activity

Brown, C. H., Russell, J. A., & Leng, G. (2000) · Neuroscience Research · doi:10.1016/s0168-0102(99)00121-2 · Cited by 77 · see citing works

Does oxytocin deficiency mediate social deficits in autism?

Modahl, C., FEIN, D. A., Waterhouse, L. H., & Newton, N. R. (1992) · Journal of Autism and Developmental Disorders · doi:10.1007/bf01048246 · Cited by 72 · see citing works

Quantitative autoradiography of μ-,δ- and κ1 opioid receptors in κ-opioid receptor knockout mice

Slowe, S. J., Simonin, F., Kieffer, B. L., & Kitchen, I. (1999) · Brain Research · doi:10.1016/s0006-8993(98)01201-3 · Cited by 71 · see citing works

Mu-opioid receptor (OPRM1) variation, oxytocin levels and maternal attachment in free-ranging rhesus macaques Macaca mulatta

Higham, J. P., Barr, C. S., Hoffman, C. L., Mandalaywala, T. M., Parker, K. J., & Maestripieri, D. (2011) · Behavioral Neuroscience · doi:10.1037/a0022695 · Cited by 69 · see citing works

Inhibition of Oxytocin Release by Morphine and Its Analogs

Haldar, J., & Sawyer, W. H. (1978) · Experimental Biology and Medicine · doi:10.3181/00379727-157-40080 · Cited by 61 · see citing works

Modeling socially anhedonic syndromes: genetic and pharmacological manipulation of opioid neurotransmission in mice

Cinque, C., Pondiki, S., Oddi, D., Certo, M. G. D., Marinelli, S., Troisi, A., Moles, A., & D'Amato, F. R. (2012) · Translational Psychiatry · doi:10.1038/tp.2012.83 · Cited by 58 · see citing works

Ultrasonic vocalizations in mice and rats： social contexts and functions

Costantini, F., & D'Amato, F. R. (2006) · Europe PMC (PubMed Central) · Cited by 54 · see citing works

Lack of social exploratory activation in male μ-opioid receptor KO mice in response to playback of female ultrasonic vocalizations

Wöhr, M., Moles, A., Schwarting, R. K. W., & D'Amato, F. R. (2010) · Social Neuroscience · doi:10.1080/17470911003765560 · Cited by 45 · see citing works

Intranasal application of vasopressin fails to elicit changes in brain immediate early gene expression, neural activity and behavioural performance of rats

Ludwig, M., Tobin, V. A., Callahan, M. F., Papadaki, E., Becker, A., Engelmann, M., & Leng, G. (2013) · Journal of Neuroendocrinology · doi:10.1111/jne.12046 · Cited by 37 · see citing works

Adolescent exposure to oxytocin, but not the selective oxytocin receptor agonist TGOT, increases social behavior and plasma oxytocin in adulthood

Suraev, A. S., Bowen, M. T., Ali, S. O., Hicks, C., Ramos, L., & McGregor, I. S. (2014) · Hormones and Behavior · doi:10.1016/j.yhbeh.2014.03.002 · Cited by 35 · see citing works

Opioid Modulation of Oxytocin Release

Morris, M. S., Domino, E. F., & Domino, S. E. (2010) · The Journal of Clinical Pharmacology · doi:10.1177/0091270010361256 · Cited by 28 · see citing works

Assembling the puzzle: pathways of oxytocin signaling in the brain

Grinevich, V., Knobloch-Bollmann, H. S., Eliava, M., Busnelli, M., & Chini, B. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2015.04.013 · Cited by 309 · see citing works

Oxytocin Signaling in the Central Amygdala Modulates Emotion Discrimination in Mice

Ferretti, V., Maltese, F., Contarini, G., Nigro, M., Bonavia, A., Huang, H., Gigliucci, V., Morelli, G., Scheggia, D., Managò, F., et al. (2019) · Current Biology · doi:10.1016/j.cub.2019.04.070 · Cited by 212 · see citing works

Ontogenesis of oxytocin pathways in the mammalian brain: late maturation and psychosocial disorders

Grinevich, V., Desarménien, M. G., Chini, B., Tauber, M., & Muscatelli, F. (2015) · Frontiers in Neuroanatomy · doi:10.3389/fnana.2014.00164 · Cited by 121 · see citing works

μ opioid receptor, social behaviour and autism spectrum disorder: reward matters

Pellissier, L. P., Gandía, J., Laboute, T., Becker, J. A. J., & Merrer, J. L. (2017) · British Journal of Pharmacology · doi:10.1111/bph.13808 · Cited by 111 · see citing works

From Autism to Eating Disorders and More: The Role of Oxytocin in Neuropsychiatric Disorders

Romano, A., Tempesta, B., Bonaventura, M. V. M. D., & Gaetani, S. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00497 · Cited by 102 · see citing works

Ultrasonic vocalizations as a fundamental tool for early and adult behavioral phenotyping of Autism Spectrum Disorder rodent models

Caruso, A., Ricceri, L., & Scattoni, M. L. (2020) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2020.06.011 · Cited by 85 · see citing works

Endogenous opiates and behavior: 2014

Bodnar, R. J. (2015) · Peptides · doi:10.1016/j.peptides.2015.10.009 · Cited by 85 · see citing works

Neonatal Oxytocin Treatment Ameliorates Autistic-Like Behaviors and Oxytocin Deficiency in Valproic Acid-Induced Rat Model of Autism

Dai, Y., Zhang, H., Schön, M., Böckers, T. M., Han, S., Han, J., & Zhang, R. (2018) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2018.00355 · Cited by 82 · see citing works

Transient oxytocin signaling primes the development and function of excitatory hippocampal neurons

Ripamonti, S., Ambrozkiewicz, M. C., Guzzi, F., Gravati, M., Biella, G. R., Bormuth, I., Hammer, M., Tuffy, L. P., Sigler, A., Kawabe, H., et al. (2017) · eLife · doi:10.7554/elife.22466 · Cited by 82 · see citing works

Oxytocin normalizes altered circuit connectivity for social rescue of the Cntnap2 knockout mouse

Choe, K. Y., Bethlehem, R. A. I., Safrin, M., Dong, H., Salman, E., Li, Y., Grinevich, V., Golshani, P., DeNardo, L. A., Peñagarikano, O., et al. (2021) · Neuron · doi:10.1016/j.neuron.2021.11.031 · Cited by 77 · see citing works

Does environmental exposure to the greenhouse gas, N 2 O, contribute to etiological factors in neurodevelopmental disorders? A mini-review of the evidence

Fluegge, K. (2016) · Environmental Toxicology and Pharmacology · doi:10.1016/j.etap.2016.08.013 · Cited by 67 · see citing works

Altered Behaviors and Impaired Synaptic Function in a Novel Rat Model With a Complete Shank3 Deletion

Song, T.-J., Lan, X.-Y., Wei, M., Zhai, F.-J., Boeckers, T. M., Wang, J., Yuan, S., Jin, M.-Y., Xie, Y., Dang, W.-W., et al. (2019) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00111 · Cited by 64 · see citing works

Oxytocin and opioid addiction revisited: old drug, new applications

Zanos, P., Georgiou, P., Weber, C. D., Robinson, F., Kouimtsidis, C., Niforooshan, R., & Bailey, A. (2017) · British Journal of Pharmacology · doi:10.1111/bph.13757 · Cited by 54 · see citing works

LIT-001, the First Nonpeptide Oxytocin Receptor Agonist that Improves Social Interaction in a Mouse Model of Autism

Frantz, M., Pellissier, L. P., Pflimlin, E., Loison, S., Gandía, J., MARSOL, C., Durroux, T., Mouillac, B., Becker, J. A. J., Merrer, J. L., et al. (2018) · Journal of Medicinal Chemistry · doi:10.1021/acs.jmedchem.8b00697 · Cited by 57 · see citing works

Genetic mechanisms of parenting

Mileva‐Seitz, V. R., Bakermans‐Kranenburg, M. J., & van IJzendoorn, M. H. (2015) · Hormones and Behavior · doi:10.1016/j.yhbeh.2015.06.003 · Cited by 55 · see citing works

The oxytocin analogue carbetocin prevents priming-induced reinstatement of morphine-seeking: Involvement of dopaminergic, noradrenergic and MOPr systems

Georgiou, P., Zanos, P., García-Carmona, J. A., Hourani, S. M. O., Kitchen, I., Kieffer, B. L., Laorden, M. L., & Bailey, A. (2015) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2015.09.015 · Cited by 50 · see citing works

Effect of social odor context on the emission of isolation-induced ultrasonic vocalizations in the BTBR T+tf/J mouse model for autism

Wöhr, M. (2015) · Frontiers in Neuroscience · doi:10.3389/fnins.2015.00073 · Cited by 43 · see citing works

Autism Spectrum Disorders and Drug Addiction: Common Pathways, Common Molecules, Distinct Disorders?

Rothwell, P. E. (2016) · Frontiers in Neuroscience · doi:10.3389/fnins.2016.00020 · Cited by 37 · see citing works

Gut-Amygdala Interactions in Autism Spectrum Disorders: Developmental Roles via regulating Mitochondria, Exosomes, Immunity and microRNAs

Seo, M., & Anderson, G. (2019) · Current Pharmaceutical Design · doi:10.2174/1381612825666191105102545 · Cited by 38 · see citing works

Oxytocin and Animal Models for Autism Spectrum Disorder

Wagner, S., & Harony‐Nicolas, H. (2017) · Current topics in behavioral neurosciences · doi:10.1007/7854_2017_15 · Cited by 36 · see citing works

The neurochemistry of social reward during development: What have we learned from rodent models?

Manduca, A., Carbone, E., Schiavi, S., Cacchione, C., Buzzelli, V., Campolongo, P., & Trezza, V. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15321 · Cited by 34 · see citing works

Opposing effects of antibiotics and germ-free status on neuropeptide systems involved in social behaviour and pain regulation

Johnson, K. V. ‐., & Burnet, P. W. J. (2020) · BMC Neuroscience · doi:10.1186/s12868-020-00583-3 · Cited by 31 · see citing works

Maternal Weaning Modulates Emotional Behavior and Regulates the Gut-Brain Axis

Farshim, P. P., Walton, G., Chakrabarti, B., Givens, D. I., Saddy, D., Kitchen, I., Swann, J. R., & Bailey, A. (2016) · Scientific Reports · doi:10.1038/srep21958 · Cited by 32 · see citing works

Molecular mechanisms for targeted ASD treatments

Basilico, B., Morandell, J., & Novarino, G. (2020) · Current Opinion in Genetics & Development · doi:10.1016/j.gde.2020.06.004 · Cited by 30 · see citing works

Behavioral, neuromorphological, and neurobiochemical effects induced by omega-3 fatty acids following basal forebrain cholinergic depletion in aged mice

Cutuli, D., Landolfo, E., Nobili, A., Bartolo, P. D., Sacchetti, S., Chirico, D., Marini, F., Pieroni, L., Ronci, M., D’Amelio, M., et al. (2020) · Alzheimer s Research & Therapy · doi:10.1186/s13195-020-00705-3 · Cited by 29 · see citing works

An urgent need of experimental animal model of autism in drug development

Ruhela, R. K., Prakash, A., & Medhi, B. (2015) · Annals of Neurosciences · doi:10.5214/ans.0972.7531.220210 · Cited by 23 · see citing works

Back-translating behavioral intervention for autism spectrum disorders to mice with blunted reward restores social abilities

Pujol, C., Pellissier, L. P., Clément, C., Becker, J. A. J., & Merrer, J. L. (2018) · Translational Psychiatry · doi:10.1038/s41398-018-0247-y · Cited by 22 · see citing works

Region-specific up-regulation of oxytocin receptor binding in the brain of mice following chronic nicotine administration

Zanos, P., Georgiou, P., Metaxas, A., Kitchen, I., Winsky‐Sommerer, R., & Bailey, A. (2015) · Neuroscience Letters · doi:10.1016/j.neulet.2015.05.054 · Cited by 23 · see citing works

Post-weaning A1/A2 β-casein milk intake modulates depressive-like behavior, brain μ-opioid receptors, and the metabolome of rats

Osman, A., Zuffa, S., Walton, G., Fagbodun, E. O., Zanos, P., Georgiou, P., Kitchen, I., Swann, J. R., & Bailey, A. (2021) · iScience · doi:10.1016/j.isci.2021.103048 · Cited by 24 · see citing works

Clinical potential of oxytocin in autism spectrum disorder: current issues and future perspectives

Benner, S., & Yamasue, H. (2017) · Behavioural Pharmacology · doi:10.1097/fbp.0000000000000341 · Cited by 19 · see citing works

The mu opioid receptor and the orphan receptor GPR151 contribute to social reward in the habenula

Allain, F., Carter, M., Dumas, S., Darcq, E., & Kieffer, B. L. (2022) · Scientific Reports · doi:10.1038/s41598-022-24395-z · Cited by 20 · see citing works

Chronic sodium bromide treatment relieves autistic-like behavioral deficits in three mouse models of autism

Derieux, C., Léauté, A., Brugoux, A., Jaccaz, D., Terrier, C., Pin, J., Kniazeff, J., Merrer, J. L., & Becker, J. A. J. (2022) · Neuropsychopharmacology · doi:10.1038/s41386-022-01317-1 · Cited by 16 · see citing works

The Role of the Oxytocin/Arginine Vasopressin System in Animal Models of Autism Spectrum Disorder

Zhang, R., Xu, X., Zhang, H.-F., Han, S., & Han, J. (2017) · Advances in anatomy, embryology and cell biology · doi:10.1007/978-3-319-52498-6_8 · Cited by 16 · see citing works

Oxytocin and the social facilitation of placebo effects

Itskovich, E., Bowling, D. L., Garner, J. P., & Parker, K. J. (2022) · Molecular Psychiatry · doi:10.1038/s41380-022-01515-9 · Cited by 16 · see citing works

Rodent Vocalization Studies in Animal Models of the Autism Spectrum Disorder

Scattoni, M. L., Michetti, C., & Ricceri, L. (2018) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-12-809600-0.00042-1 · Cited by 13 · see citing works

Transcriptome Analysis in Hippocampus of Rats Prenatally Exposed to Valproic Acid and Effects of Intranasal Treatment of Oxytocin

Matsuo, K., Shinoda, Y., Abolhassani, N., Nakabeppu, Y., & Fukunaga, K. (2022) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2022.859198 · Cited by 13 · see citing works

Intracranial mast cells contribute to the control of social behavior in male mice

Tanioka, D., Chikahisa, S., Shimizu, N., Shiuchi, T., Sakai, N., Nishino, S., & Séi, H. (2021) · Behavioural Brain Research · doi:10.1016/j.bbr.2021.113143 · Cited by 14 · see citing works

Maturation of nucleus accumbens synaptic transmission signals a critical period for the rescue of social deficits in a mouse model of autism spectrum disorder

Matthiesen, M., Khlaifia, A., Steininger, C. F. D., Dadabhoy, M., Mumtaz, U., & Arruda-Carvalho, M. (2023) · Molecular Brain · doi:10.1186/s13041-023-01028-8 · Cited by 13 · see citing works

Oxytocin: A Multi-Functional Biomolecule with Potential Actions in Dysfunctional Conditions; From Animal Studies and Beyond

Tsingotjidou, A. (2022) · Biomolecules · doi:10.3390/biom12111603 · Cited by 15 · see citing works

Region-Specific KCC2 Rescue by rhIGF-1 and Oxytocin in a Mouse Model of Rett Syndrome

Gigliucci, V., Teutsch, J., Woodbury‐Smith, M., Luoni, M., Busnelli, M., Chini, B., & Banerjee, A. (2021) · Cerebral Cortex · doi:10.1093/cercor/bhab388 · Cited by 12 · see citing works

Effects of a Gut Microbiome Toxin, p-Cresol, on the Indices of Social Behavior in Rats

Tevzadze, G., Oniani, N., Zhuravliova, E., Darchia, N., Eliozishvili, M., Gogichadze, M., Lortkipanidze, N., Oniani, T., Kakabadze, A., Kakabadze, Z., et al. (2018) · Neurophysiology · doi:10.1007/s11062-019-09764-1 · Cited by 12 · see citing works

Acute, chronic and conditioned effects of intranasal oxytocin in the mu-opioid receptor knockout mouse model of autism: Social context matters

Pantouli, F., Pujol, C., Derieux, C., Fonteneau, M., Pellissier, L. P., MARSOL, C., Karpenko, J., Bonnet, D., Hibert, M., Bailey, A., et al. (2024) · Neuropsychopharmacology · doi:10.1038/s41386-024-01915-1 · Cited by 11 · see citing works

Modulation of the thermosensory system by oxytocin

Zayan, U., Prato, L. C. D., Muscatelli, F., & Matarazzo, V. A. (2023) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2022.1075305 · Cited by 12 · see citing works

Oxytocin and autism: Insights from clinical trials and animal models

Xing, C., & Yu, X. (2025) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2025.103015 · Cited by 11 · see citing works

A multiscale atlas of Oprm1-expressing neurons in the central nervous system: Brain-wide distribution, circuit functions, and translational therapeutic implications

Zhang, Z., Hu, S., Geng, S., Xu, T., Liu, X., Lei, Z., Sun, C., Sun, H., Xie, W., & Mu, M. (2025) · Neurochemistry International · doi:10.1016/j.neuint.2025.105998 · Cited by 7 · see citing works

New Treatment Perspectives in Autism Spectrum Disorders

Canitano, R., & Bozzi, Y. (2015) · Frontiers in Pediatrics · doi:10.3389/fped.2015.00022 · Cited by 6 · see citing works

Oxytocin seals the blood–brain barrier, improving 22q11.2 deletion syndrome trajectories

Castellani, G., Ciampoli, M., Benedetti, A., Ferretti, V., Trigilio, G., Barcik, W., Busnelli, M., Contarini, G., Paolini, C., Devroye, C., et al. (2025) · Brain · doi:10.1093/brain/awaf112 · Cited by 5 · see citing works

Effects of a Gut Microbiome Toxin, p-Cresol, on the Contents of the NMDA2B Receptor Subunit in the Nucl. Accumbens of Rats

Tevzadze, G., Zhuravliova, E., Meparishvili, M., Lordkipanidze, T. G., Shanshiashvili, L., Kikvidze, Z., & Mikeladze, D. (2019) · Neurophysiology · doi:10.1007/s11062-019-09795-8 · Cited by 4 · see citing works

Oxytocin in the Developing Brain

Chini, B., Leonzino, M., & Gigliucci, V. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-800109-7.00016-9 · Cited by 2 · see citing works

Specialized Networks for Social Cognition: A Defining Role for the Oxytocin Receptor

King, L. B. (2016) · Journal of Neuroscience · doi:10.1523/jneurosci.1446-16.2016 · Cited by 2 · see citing works

Additional file 2 of Behavioral, neuromorphological, and neurobiochemical effects induced by omega-3 fatty acids following basal forebrain cholinergic depletion in aged mice

Cutuli, D., Landolfo, E., Nobili, A., Bartolo, P. D., Sacchetti, S., Chirico, D., Marini, F., Pieroni, L., Ronci, M., D’Amelio, M., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13245943

Additional file 1 of Behavioral, neuromorphological, and neurobiochemical effects induced by omega-3 fatty acids following basal forebrain cholinergic depletion in aged mice

Cutuli, D., Landolfo, E., Nobili, A., Bartolo, P. D., Sacchetti, S., Chirico, D., Marini, F., Pieroni, L., Ronci, M., D’Amelio, M., et al. (2020) · Figshare · doi:10.6084/m9.figshare.13245940

Oxytocin receptors in neurodevelopmental disorders : innovative approaches for the quantification of sopramolecular receptor complexes

Santini, F. (2021) · theses.fr (ABES) · doi:10.70675/c00b0393z4da7z42caz9cd8z609df0efd23c

Effets des ions bromures dans les modèles murins d'autisme et sur la signalisation des récepteurs couplés aux protéines G

Derieux, C. (2021) · theses.fr (ABES) · doi:10.70675/e9ba9584z22eez4cbbzb118za3ef2dae7731

Efficacy of pharmacological and microbiota-based therapies in preclinical models of autism spectrum disorder: a systematic review

Kunevičius, A., Gawlińska, K., Burokas, A., & Gawliński, D. (2026) · Molecular Psychiatry · doi:10.1038/s41380-026-03663-8

BindingDB Entry 50002504: LIT-001, the First Nonpeptide Oxytocin Receptor Agonist that Improves Social Interaction in a Mouse Model of Autism.

BindingDB (2020) · UC San Diego · doi:10.7270/q24j0hrf

Reviewed by:

Gigliucci, V., Leonzino, M., Busnelli, M., Luchetti, R., Palladino, V. S., D’amato, F. R., Chini, B., Grinevich, V., Cancer, G., Colonnello, V., et al. (2014)

Acute, chronic and conditioned effects of intranasal oxytocin in the mu-opioid receptor knockout mouse model of autism: Social context matters

Pantouli, F., Pujol, C., Derieux, C., Fonteneau, M., Pellissier, L. P., MARSOL, C., Karpenko, J., Bonnet, D., Hibert, M., Bailey, A., et al. (2024) · Neuropsychopharmacology · doi:10.1038/s41386-024-01915-1 · Cited by 11 · see citing works

Oxytocin receptor knockout mice display deficits in the expression of autism-related behaviors

Pobbe, R. L. H., Pearson, B. L., Defensor, E. B., Bolivar, V. J., Young, W. S., Lee, H., Blanchard, D. C., & Blanchard, R. J. (2011) · Hormones and Behavior · doi:10.1016/j.yhbeh.2011.10.010 · Cited by 139 · see citing works

New treatment perspectives in autism spectrum disorder: Role of brain region-specific opioid system balance in ameliorating social impairments

Ago, Y. (2022) · Proceedings for Annual Meeting of The Japanese Pharmacological Society · doi:10.1254/jpssuppl.96.0_1-b-s06-4

μ-Opioid Receptor (Oprm1) Copy Number Influences Nucleus Accumbens Microcircuitry and Reciprocal Social Behaviors

Toddes, C., Lefevre, E. M., Brandner, D. D., Zugschwert, L., & Rothwell, P. E. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.2440-20.2021 · Cited by 34 · see citing works