Cited by 210Privacy-Preserving Technologies in DataArtificial Intelligence in Healthcare and EducationDomain Adaptation and Few-Shot Learning

A systematic review of federated learning in the healthcare area: From the perspective of data properties and applications

Open access
Prayitno, Shyu, Chi-Ren, Putra, Karisma Trinanda, Chen, Hsing-Chung, Tsai, Yuan-Yu, Hossain, K. S. M. Tozammel, Jiang, Wei, Shae, Zon-Yin·2021·Applied Sciences

Abstract

Recent advances in deep learning have shown many successful stories in smart healthcare applications with data-driven insight into improving clinical institutions’ quality of care. Excellent deep learning models are heavily data-driven. The more data trained, the more robust and more generalizable the performance of the deep learning model. However, pooling the medical data into centralized storage to train a robust deep learning model faces privacy, ownership, and strict regulation challenges. Federated learning resolves the previous challenges with a shared global deep learning model using a central aggregator server. At the same time, patient data remain with the local party, maintaining data anonymity and security. In this study, first, we provide a comprehensive, up-to-date review of research employing federated learning in healthcare applications. Second, we evaluate a set of recent challenges from a data-centric perspective in federated learning, such as data partitioning characteristics, data distributions, data protection mechanisms, and benchmark datasets. Finally, we point out several potential challenges and future research directions in healthcare applications.

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Crossref · 10.3390/app112311191

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Authors
Prayitno, Shyu, C.-R., Putra, K. T., Chen, H.-C., Tsai, Y.-Y., Hossain, K. S. M. T., Jiang, W., & Shae, Z.-Y.
Affiliations
  • Department of Computer Science and Information Engineering, Asia University, Taichung City 413, Taiwan
  • University of Missouri (US)
  • Asia University (TW)
Corresponding author
Shae, Zon-Yin
Venue
Applied Sciences
Publisher
MDPI AG
Published
2021-11-25
Volume
11
Issue
23
Pages
11191
ISSN
2076-3417 (ISSN-L)
OpenAlex
W3215776046
Cited by
210
References
71
Citations by year
2026: 37 · 2025: 47 · 2024: 46 · 2023: 58 · 2022: 22
FWCI
2.27
Type
journal article
Language
en
Open access
Locations
  • Applied Sciences (publishedVersion, cc-by)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Ministry of Science and Technology (MOST 110-2321-B-468-001, MOST 110-2511-H-468-005)
Topics
  • Physical Sciences › Computer Science › Artificial Intelligence › Privacy-Preserving Technologies in Data
  • Health Sciences › Medicine › Health Informatics › Artificial Intelligence in Healthcare and Education
  • Physical Sciences › Computer Science › Artificial Intelligence › Domain Adaptation and Few-Shot Learning
Keywords
federated learning, health care, medical data privacy, data partitioning, data distribution skew, data protection mechanisms, benchmark dataset, smart healthcare

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