Beta-Glucans Improve Growth, Viability and Colonization of Probiotic Microorganisms
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Probiotics, prebiotics and synbiotics are frequently-used components for the elaboration of functional food. Currently, most of the commercialized probiotics are limited to a few strains of the genera Bifidobacteria, Lactobacillus and Streptococcus, most of which produce exopolysaccharides (EPS). This suggests that the beneficial properties of these microorganisms may be related to the biological activities of these biopolymers. In this work we report that a 2-substituted-(1,3)-β-d-glucan of non-dairy bacterial origin has a prebiotic effect on three probiotic strains. Moreover, the presence of this β-d-glucan potentiates in vitro adhesion of the probiotic Lactobacillus plantarum WCFS1 to human intestinal epithelial cells.
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β-D-glucan produced from P. parvulus 2.6 has been shown to enhance growth and increase adherence to intestinal cells of different probiotic strains in vitro.
“β-D-glucan produced from P. parvulus 2.6 has been shown to enhance the growth and increase adherence to intestinal cells of different probiotic strains in vitro [165]”
From Lactic Acid Bacteria Exopolysaccharides Producers: A Sustainable Tool for Functional Foods (2021) · cites this paper as [165]
The Introduction and Conclusions (pages unavailable in our copy) report that the P. parvulus 2.6 β-D-glucan supported growth of three probiotic strains. The Results and Discussion report increased in vitro adhesion to human intestinal cells, but test that effect only for L. plantarum WCFS1, not for different probiotic strains. (LLM, conf=0.89)
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- Authors
- Russo, P., López, P., Capozzi, V., De Palencia, P. F., Dueñas, M. T., Spano, G., & Fiocco, D.
- Affiliations
- University of Foggia (IT)
- Centro de Investigaciones Biológicas Margarita Salas (ES)
- Biology Research Center, Department of Molecular Microbiology and Infection Biology, 28040 Madrid, Spain
- University of the Basque Country (ES)
- Corresponding author
- Spano, Giuseppe
- ORCID
- Venue
- International Journal of Molecular Sciences
- Publisher
- MDPI AG
- Published
- 2012-05-18
- Volume
- 13
- Issue
- 5
- Pages
- 6026-6039
- ISSN
- 1422-0067 (ISSN-L)
- PMC
- PMC3382753
- OpenAlex
- W2024105035
- Cited by
- 176
- References
- 42
- Citations by year
- 2026: 6 · 2025: 8 · 2024: 6 · 2023: 17 · 2022: 21 · 2021: 18 · 2020: 23 · 2019: 10 · 2018: 15 · 2017: 16 · 2016: 5 · 2015: 12 · 2014: 7 · 2013: 9 · 2012: 3
- FWCI
- 15.22
- Type
- journal article
- Language
- en
- Open access
- gold
- doi.org
- Licence
- Locations
- International Journal of Molecular Sciences (publishedVersion, cc-by)
- Europe PMC (PubMed Central) (publishedVersion, cc-by)
- PubMed Central (publishedVersion, cc-by)
- PubMed (publishedVersion)
- Communities in ADDI (Universidad del Pais Vasco) (submittedVersion, cc-by)
- Archivio Istituzionale della Ricerca (Universita Degli Studi Di Milano) (submittedVersion, other-oa)
- DIGITAL.CSIC (Spanish National Research Council (CSIC)) (submittedVersion, cc-by)
- LA Referencia (Red Federada de Repositorios Institucionales de Publicaciones Científicas) (submittedVersion, cc-by)
- DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
- Hispana (submittedVersion, cc-by)
- Topics
- Life Sciences › Agricultural and Biological Sciences › Food Science › Probiotics and Fermented Foods
- Health Sciences › Nursing › Nutrition and Dietetics › Microbial Metabolites in Food Biotechnology
- Life Sciences › Agricultural and Biological Sciences › Food Science › Polysaccharides Composition and Applications
- Keywords
- β-glucan, prebiotics, probiotics, Lactobacillus plantarum WCFS1, bacterial adhesion, intestinal epithelial cells, exopolysaccharides, probiotic viability, colonization, functional foods
- MeSH terms
- Bacterial Proteins, Bifidobacterium, Cell Adhesion, Glucosidases, Humans, Proteoglycans, Streptococcus, Caco-2 Cells, Probiotics, beta-Glucans, Lactiplantibacillus plantarum, Prebiotics
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