The DOI matches its Crossref record; 41 of the 41 references it cites were found in a registry or an index.
Whole Fruits and Fruit Fiber Emerging Health Effects
Open accessAbstract
Less than 10% of most Western populations consume adequate levels of whole fruits and dietary fiber with typical intake being about half of the recommended levels. Evidence of the beneficial health effects of consuming adequate levels of whole fruits has been steadily growing, especially regarding their bioactive fiber prebiotic effects and role in improved weight control, wellness and healthy aging. The primary aim of this narrative review article is to examine the increasing number of health benefits which are associated with the adequate intake of whole fruits, especially fruit fiber, throughout the human lifecycle. These potential health benefits include: protecting colonic gastrointestinal health (e.g., constipation, irritable bowel syndrome, inflammatory bowel diseases, and diverticular disease); promoting long-term weight management; reducing risk of cardiovascular disease, type 2 diabetes and metabolic syndrome; defending against colorectal and lung cancers; improving odds of successful aging; reducing the severity of asthma and chronic obstructive pulmonary disease; enhancing psychological well-being and lowering the risk of depression; contributing to higher bone mineral density in children and adults; reducing risk of seborrheic dermatitis; and helping to attenuate autism spectrum disorder severity. Low whole fruit intake represents a potentially more serious global population health threat than previously recognized, especially in light of the emerging research on whole fruit and fruit fiber health benefits.
Overview
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Integrity signals
Registry
Cites
Statistics
Verification
Claims the paper makes
The claims and statistics of this paper haven’t been checked yet.
Run the check — free, no account needed. It reads the open-access text and checks the sources it cites.
Self-check
Percentages, sums and reported differences re-computed from the paper’s own numbers.
The self-check needs the paper’s full text.
Citations
Cites
Aune, D., Giovannucci, E., Boffetta, P., Fadnes, L. T., Keum, N., Norat, T., Greenwood, D. C., Riboli, E., Vatten, L. J., & Tonstad, S. (2017) · International Journal of Epidemiology · doi:10.1093/ije/dyw319 · Cited by 2,419
Fiber and prebiotics: Mechanisms and health benefits
Slavin, J. (2013) · Nutrients · doi:10.3390/nu5041417 · Cited by 2,340
Gut bacteria selectively promoted by dietary fibers alleviate type 2 diabetes
Zhao, L., Zhang, F., Ding, X., Wu, G., Lam, Y. Y., Wang, X., Fu, H., Xue, X., Lu, C., Ma, J., et al. (2018) · Science · doi:10.1126/science.aao5774 · Cited by 2,304
De Filippis, F., Pellegrini, N., Vannini, L., Jeffery, I. B., La Storia, A., Laghi, L., Serrazanetti, D. I., Di Cagno, R., Ferrocino, I., Lazzi, C., et al. (2016) · Gut · doi:10.1136/gutjnl-2015-309957 · Cited by 1,638
Samuel, B. S., Shaito, A., Motoike, T., Rey, F. E., Backhed, F., Manchester, J. K., Hammer, R. E., Williams, S. C., Crowley, J., Yanagisawa, M., et al. (2008) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.0808567105 · Cited by 1,564
Gut Dysbiosis Is Linked to Hypertension
Yang, T., Santisteban, M. M., Rodriguez, V., Li, E., Ahmari, N., Carvajal, J. M., Zadeh, M., Gong, M., Qi, Y., Zubcevic, J., et al. (2015) · Hypertension · doi:10.1161/hypertensionaha.115.05315 · Cited by 1,478
Hou, J. K., Abraham, B., & El-Serag, H. (2011) · American Journal of Gastroenterology · doi:10.1038/ajg.2011.44 · Cited by 1,009 · cited 2×
“A meta-analysis (10 case-control studies) [79], a systematic review (5 cohort or case-control studies) [80], and The Nurses’ Health Study [81] found that increased fruit intake reduced CD risk in these populations by approximately 40%.”
BackgroundMethodFat, fibre and cancer risk in African Americans and rural Africans
O’Keefe, S. J. D., Li, J. V., Lahti, L., Ou, J., Carbonero, F., Mohammed, K., Posma, J. M., Kinross, J., Wahl, E., Ruder, E., et al. (2015) · Nature Communications · doi:10.1038/ncomms7342 · Cited by 982
Stephen, A. M., Champ, M. M.-J., Cloran, S. J., Fleith, M., van Lieshout, L., Mejborn, H., & Burley, V. J. (2017) · Nutrition Research Reviews · doi:10.1017/s095442241700004x · Cited by 798
Siervo, M., Lara, J., Chowdhury, S., Ashor, A., Oggioni, C., & Mathers, J. C. (2015) · British Journal of Nutrition · doi:10.1017/s0007114514003341 · Cited by 656
Muraki, I., Imamura, F., Manson, J. E., Hu, F. B., Willett, W. C., van Dam, R. M., & Sun, Q. (2013) · BMJ · doi:10.1136/bmj.f5001 · Cited by 544
Dietary fiber and health outcomes: an umbrella review of systematic reviews and meta-analyses
Veronese, N., Solmi, M., Caruso, M. G., Giannelli, G., Osella, A. R., Evangelou, E., Maggi, S., Fontana, L., Stubbs, B., & Tzoulaki, I. (2018) · The American Journal of Clinical Nutrition · doi:10.1093/ajcn/nqx082 · Cited by 536
Water-soluble dietary fibers and cardiovascular disease
Theuwissen, E., & Mensink, R. P. (2008) · Physiology & Behavior · doi:10.1016/j.physbeh.2008.01.001 · Cited by 488
Position of the Academy of Nutrition and Dietetics: Health implications of dietary fiber
Dahl, W. J., & Stewart, M. L. (2015) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2015.09.003 · Cited by 471
Whelton, S. P., Hyre, A. D., Pedersen, B., Yi, Y., Whelton, P. K., & He, J. (2005) · Journal of Hypertension · doi:10.1097/01.hjh.0000160199.51158.cf · Cited by 465
Ileal brake: a sensible food target for appetite control. A review
Maljaars, P. W. J., Peters, H. P. F., Mela, D. J., & Masclee, A. A. M. (2008) · Physiology & Behavior · doi:10.1016/j.physbeh.2008.07.018 · Cited by 451
Bertoia, M. L., Mukamal, K. J., Cahill, L. E., Hou, T., Ludwig, D. S., Mozaffarian, D., Willett, W. C., Hu, F. B., & Rimm, E. B. (2015) · PLOS Medicine · doi:10.1371/journal.pmed.1001878 · Cited by 397 · cited 1×
“Associations between a daily serving of specific non-juice fruits and vegetables and weight change in US men and women over 4 years from the Nurses’ Health Studies and Health Professionals Follow-up Study (pooled data; multivariate adjusted; *excludes French fries and potato chips) [96].”
BackgroundGut microbiota richness promotes its stability upon increased dietary fibre intake in healthy adults
Tap, J., Furet, J., Bensaada, M., Philippe, C., Roth, H., Rabot, S., Lakhdari, O., Lombard, V., Henrissat, B., Corthier, G., et al. (2015) · Environmental Microbiology · doi:10.1111/1462-2920.13006 · Cited by 397
A prebiotic intervention study in children with autism spectrum disorders (ASDs)
Grimaldi, R., Gibson, G. R., Vulevic, J., Giallourou, N., Castro-Mejía, J. L., Hansen, L. H., Leigh Gibson, E., Nielsen, D. S., & Costabile, A. (2018) · Microbiome · doi:10.1186/s40168-018-0523-3 · Cited by 369
Bradbury, K. E., Appleby, P. N., & Key, T. J. (2014) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.113.071357 · Cited by 328
Dietary fiber for the treatment of type 2 diabetes mellitus: a meta-analysis
Post, R. E., Mainous, A. G., King, D. E., & Simpson, K. N. (2012) · The Journal of the American Board of Family Medicine · doi:10.3122/jabfm.2012.01.110148 · Cited by 302 · cited 1×
“55 mg/dL compared to a control over 3–24 weeks [234,235].”
BackgroundLindström, J., Peltonen, M., Eriksson, J. G., Louheranta, A., Fogelholm, M., Uusitupa, M., & Tuomilehto, J. (2006) · Diabetologia · doi:10.1007/s00125-006-0198-3 · Cited by 293
Prebiotics, bone and mineral metabolism
Whisner, C. M., & Castillo, L. F. (2018) · Calcified Tissue International · doi:10.1007/s00223-017-0339-3 · Cited by 292
Fruits and Vegetables Consumption and Risk of Stroke: A Meta-Analysis of Prospective Cohort Studies
Hu, D., Huang, J., Wang, Y., Zhang, D., & Qu, Y. (2014) · Stroke · doi:10.1161/strokeaha.114.004836 · Cited by 258 · cited 1×
“A meta-analysis (20 cohort studies; 760,629 participants) found a linear dose-response relationship with reduced stroke risk for fruits by 32% and for vegetables by 11% per 200 g/day with citrus fruits, apples, pears, and green leafy vegetables being the most effective in reducing stroke risk [284].”
BackgroundSchwingshackl, L., Hoffmann, G., Kalle-Uhlmann, T., Arregui, M., Buijsse, B., & Boeing, H. (2015) · PLOS ONE · doi:10.1371/journal.pone.0140846 · Cited by 218
Conner, T. S., Brookie, K. L., Carr, A. C., Mainvil, L. A., & Vissers, M. C. M. (2017) · PLOS ONE · doi:10.1371/journal.pone.0171206 · Cited by 207
Byrne, C. S., Chambers, E. S., Alhabeeb, H., Chhina, N., Morrison, D. J., Preston, T., Tedford, C., Fitzpatrick, J., Irani, C., Busza, A., et al. (2016) · The American Journal of Clinical Nutrition · doi:10.3945/ajcn.115.126706 · Cited by 201
Baer, D. J., Rumpler, W. V., Miles, C. W., & Fahey, G. C. (1997) · The Journal of Nutrition · doi:10.1093/jn/127.4.579 · Cited by 201
Fiber Intake and Survival After Colorectal Cancer Diagnosis
Song, M., Wu, K., Meyerhardt, J. A., Ogino, S., Wang, M., Fuchs, C. S., Giovannucci, E. L., & Chan, A. T. (2018) · JAMA Oncology · doi:10.1001/jamaoncol.2017.3684 · Cited by 197
The dynamic plasticity of insulin production in β-cells
Boland, B. B., Rhodes, C. J., & Grimsby, J. S. (2017) · Molecular Metabolism · doi:10.1016/j.molmet.2017.04.010 · Cited by 194
Rabbani, G. H., Teka, T., Zaman, B., Majid, N., Khatun, M., & Fuchs, G. J. (2001) · Gastroenterology · doi:10.1053/gast.2001.27178 · Cited by 175
Sharp, W. G., Postorino, V., McCracken, C. E., Berry, R. C., Criado, K. K., Burrell, T. L., & Scahill, L. (2018) · Journal of the Academy of Nutrition and Dietetics · doi:10.1016/j.jand.2018.05.005 · Cited by 167 · cited 1×
“Diets of children with ASD often consist of fewer than 20 foods, repetitive eating patterns, and nutrient inadequacies, which can lead to increased colonic microbiota dysbiosis, gastrointestinal distress, flatulence and abdominal pain and lower intakes of fiber such as pectin and vitamin C, suggesting low fruit intake…”
BackgroundMcCall, D. O., McGartland, C. P., McKinley, M. C., Patterson, C. C., Sharpe, P., McCance, D. R., Young, I. S., & Woodside, J. V. (2009) · Circulation · doi:10.1161/circulationaha.108.831297 · Cited by 161 · cited 2×
“A dose response RCT (117 adults; 12 weeks) showed that each serving of fruits and vegetables significantly increased forearm blood flow by 6% in hypertensive subjects [190].”
BackgroundDietary Fiber Intake Reduces Risk for Colorectal Adenoma: A Meta-analysis
Ben, Q., Sun, Y., Chai, R., Qian, A., Xu, B., & Yuan, Y. (2014) · Gastroenterology · doi:10.1053/j.gastro.2013.11.003 · Cited by 156 · cited 1×
“A meta-analysis of 20 observational studies [267] and another meta-analysis of 5 cohort and 17 case-control studies [268] showed that each 10-g fruit fiber and high fruit intake reduced adenoma risk by 21% compared to a reduced risk of 9% for vegetables.”
MethodGrimaldi, R., Cela, D., Swann, J. R., Vulevic, J., Gibson, G. R., Tzortzis, G., & Costabile, A. (2017) · FEMS Microbiology Ecology · doi:10.1093/femsec/fiw233 · Cited by 109
Myint, P. K., Welch, A. A., Bingham, S. A., Surtees, P. G., Wainwright, N. W., Luben, R. N., Wareham, N. J., Smith, R. D., Harvey, I. M., Day, N. E., et al. (2007) · Public Health Nutrition · doi:10.1017/s1368980007222608 · Cited by 94
Total, insoluble and soluble dietary fibre intake in relation to blood pressure: the INTERMAP Study
Aljuraiban, G. S., Griep, L. M. O., Chan, Q., Daviglus, M. L., Stamler, J., Van Horn, L., Elliott, P., & Frost, G. S. (2015) · British Journal of Nutrition · doi:10.1017/s0007114515003098 · Cited by 82
Exploration of the association between dietary fiber intake and depressive symptoms in adults
Xu, H., Li, S., Song, X., Li, Z., & Zhang, D. (2018) · Nutrition · doi:10.1016/j.nut.2018.03.009 · Cited by 76
Looman, M., Schoenaker, D. A. J. M., Soedamah-Muthu, S. S., Geelen, A., Feskens, E. J. M., & Mishra, G. D. (2018) · British Journal of Nutrition · doi:10.1017/s0007114518001277 · Cited by 64
Global status of diabetes prevention and prospects for action: A consensus statement
Ibrahim, M., Tuomilehto, J., Aschner, P., Beseler, L., Cahn, A., Eckel, R. H., Fischl, A. H., Guthrie, G., Hill, J. O., Kumwenda, M., et al. (2018) · Diabetes/Metabolism Research and Reviews · doi:10.1002/dmrr.3021 · Cited by 52
Morimoto, N., Kasuga, C., Tanaka, A., Kamachi, K., Ai, M., Urayama, K. Y., & Tanaka, A. (2018) · British Journal of Nutrition · doi:10.1017/s0007114517003725 · Cited by 26
Cited by
Environmental Influences on the Human Microbiome and Implications for Noncommunicable Disease
Ahn, J., & Hayes, R. B. (2021) · Annual Review of Public Health · doi:10.1146/annurev-publhealth-012420-105020 · Cited by 186
Exploration of the association between dietary fiber intake and depressive symptoms in adults
Xu, H., Li, S., Song, X., Li, Z., & Zhang, D. (2018) · Nutrition · doi:10.1016/j.nut.2018.03.009 · Cited by 76
Effects of fresh mango consumption on cardiometabolic risk factors in overweight and obese adults
Rosas, M., Pinneo, S., O'Mealy, C., Tsang, M., Liu, C., Kern, M., Hooshmand, S., & Hong, M. Y. (2022) · Nutrition, Metabolism and Cardiovascular Diseases · doi:10.1016/j.numecd.2021.11.001 · Cited by 25
Metadata
- Authors
- Dreher, M.
- Venue
- Nutrients
- Publisher
- MDPI AG
- Published
- 2018-11-28
- Volume
- 10
- Issue
- 12
- Pages
- 1833
- ISSN
- 2072-6643 (ISSN-L)
- OpenAlex
- W2902711295
- Cited by
- 370
- References
- 41
- FWCI
- 33.70
- Type
- journal article
- Language
- en
- Open access
- gold
About these checks
Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.
Statistics and arithmetic are recomputed, not judged.
Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.
What counts as a claim ›How we measure confidence ›How we check this ›
Are you an author, or do you see a problem with this page? Request a review
Data sources
Bibliographic data: Semantic Scholar, OpenAlex, Crossref.
Contains information from the Semantic Scholar Academic Graph Datasets, made available under the ODC Attribution License (ODC-BY 1.0).
Semantic Scholar’s data is described in: Kinney, R., et al. (2023). The Semantic Scholar Open Data Platform. arXiv:2301.10140.
