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Cited by 93Natural Antidiabetic Agents StudiesMedicinal Plant ResearchEthnobotanical and Medicinal Plants Studies

Some common medicinal plants with antidiabetic activity, known and available in Europe (A mini-review)

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Przeor, Monika·2022·Pharmaceuticals
DOI 10.3390/ph15010065PMC PMC8778315
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Abstract

Diabetes is a metabolic disease that affected 9.3% of adults worldwide in 2019. Its co-occurrence is suspected to increase mortality from COVID-19. The treatment of diabetes is mainly based on the long-term use of pharmacological agents, often expensive and causing unpleasant side effects. There is an alarming increase in the number of pharmaceuticals taken in Europe. The aim of this paper is to concisely collect information concerning the few antidiabetic or hypoglycaemic raw plant materials that are present in the consciousness of Europeans and relatively easily accessible to them on the market and sometimes even grown on European plantations. The following raw materials are discussed in this mini-review: Morus alba L., Cinnamomum zeylanicum J.Presl, Trigonella foenum-graecum L., Phaseolus vulgaris L., Zingiber officinale Rosc., and Panax ginseng C.A.Meyer in terms of scientifically tested antidiabetic activity and the presence of characteristic biologically active compounds and their specific properties, including antioxidant properties. The characteristics of these raw materials are based on in vitro as well as in vivo studies: on animals and in clinical studies. In addition, for each plant, the possibility to use certain morphological elements in the light of EFSA legislation is given.

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  • Herbals/botanicals have demonstrated potent anti-diabetic effects via a variety of mechanisms, such as enhancing insulin sensitivity, stimulating insulin secretion, blocking carbohydrate absorption, and reducing oxidative stress.

    “Herbals/botanicals have demonstrated potent anti-diabetic effects via a variety of mechanisms, such as enhancing insulin sensitivity, stimulating insulin secretion, blocking the absorption of carbohydrates, and reducing OS; the inhibition of α-glucosidase enzyme and the generation of advanced glycation products, the transcription of GLUT-4 and PPAR, and the presence of antioxidants.”

    From A critical review on diabetes mellitus type 1 and type 2 management approaches: from lifestyle modification to current and novel targets and therapeutic agents. (2024) · cites this paper as [139]

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Cited by

Sorted by citations

Authors
Przeor, M.
Affiliations
Poznań University of Life Sciences (PL)
Corresponding author
Przeor, Monika
ORCID
Przeor, Monika
Venue
Pharmaceuticals
Publisher
MDPI AG
Published
2022-01-04
Volume
15
Issue
1
Pages
65
ISSN
1424-8247 (ISSN-L)
DOI
10.3390/ph15010065
PMC
PMC8778315
OpenAlex
W4206815251
Cited by
93
References
4
Citations by year
2026: 14 · 2025: 24 · 2024: 26 · 2023: 18 · 2022: 11
FWCI
2.81
Type
journal article
Language
en
Open access
Licence
Locations
  • Pharmaceuticals (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • CeON Repository (Centre for Evaluation in Education and Science) (submittedVersion, other-oa)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Polish Ministry of Science and Higher Education (005/RID/2018/19)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Natural Antidiabetic Agents Studies
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Medicinal Plant Research
  • Life Sciences › Agricultural and Biological Sciences › Plant Science › Ethnobotanical and Medicinal Plants Studies
Keywords
medicinal plants, antidiabetic activity, hypoglycemic activity, diabetes mellitus, Morus alba, Cinnamomum zeylanicum, fenugreek, Phaseolus vulgaris, ginger, Panax ginseng, antioxidant activity, bioactive compounds, medicinal plant raw materials

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