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Cited by 46Skin Protection and AgingBioactive natural compoundsPhytochemicals and Antioxidant Activities

Plant Secondary Metabolites against Skin Photodamage: Mexican Plants, a Potential Source of UV-Radiation Protectant Molecules

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Torres-Contreras, Ana Mariel, Garcia-Baeza, Antoni, Vidal-Limon, Heriberto Rafael, Balderas-Renteria, Isaias, Ramírez-Cabrera, Mónica A., Ramirez-Estrada, Karla·2022·Plants
DOI 10.3390/plants11020220PMC PMC8779981
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Abstract

Human skin works as a barrier against the adverse effects of environmental agents, including ultraviolet radiation (UVR). Exposure to UVR is associated with a variety of harmful effects on the skin, and it is one of the most common health concerns. Solar UVR constitutes the major etiological factor in the development of cutaneous malignancy. However, more than 90% of skin cancer cases could be avoided with appropriate preventive measures such as regular sunscreen use. Plants, constantly irradiated by sunlight, are able to synthesize specialized molecules to fight against UVR damage. Phenolic compounds, alkaloids and carotenoids constitute the major plant secondary metabolism compounds with relevant UVR protection activities. Hence, plants are an important source of molecules used to avoid UVR damage, reduce photoaging and prevent skin cancers and related illnesses. Due to its significance, we reviewed the main plant secondary metabolites related to UVR protection and its reported mechanisms. In addition, we summarized the research in Mexican plants related to UV protection. We presented the most studied Mexican plants and the photoprotective molecules found in them. Additionally, we analyzed the studies conducted to elucidate the mechanism of photoprotection of those molecules and their potential use as ingredients in sunscreen formulas.

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  • Oral photoprotectants do not offer full skin protection, but they provide a boost to set photoprotection in motion in living organisms.

    “Also, oral photoprotectants do not offer full skin protection, but they provide a boost to set photoprotection in motion in living organisms (Torres-Contreras et al. 2022).”

    From Skin protection from solar ultraviolet radiation using natural compounds: a review (2024) · cites this paper as Torres-Contreras et al. 2022

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Authors
Torres-Contreras, A. M., Garcia-Baeza, A., Vidal-Limon, H. R., Balderas-Renteria, I., Ramírez-Cabrera, M. A., & Ramirez-Estrada, K.
Affiliations
  • Universidad Autónoma de Nuevo León (MX)
  • Centro de Biotecnología FEMSA, Instituto Tecnológico de Monterrey, Avenida Junco de la Vega, Col. Tecnológico, Montrerrey 65849, Mexico
  • Laboratory of Cell Metabolism, Faculty of Chemistry, Autonomous University of Nuevo León, Pedro de Alba s/n, Ciudad Universitaria, San Nicolás de los Garza 66451, Mexico
  • Laboratorio de Farmacología Molecular y Modelos Biológicos, División de Estudios de Posgrado, Facultad de Ciencias Químicas, Universidad Autónoma de Nuevo León, Av. Guerrero s/n, Col. Treviño, Monterrey 64570, Mexico
ORCID
Venue
Plants
Publisher
MDPI AG
Published
2022-01-15
Volume
11
Issue
2
Pages
220
ISSN
2223-7747 (ISSN-L)
DOI
10.3390/plants11020220
PMC
PMC8779981
OpenAlex
W4206454344
Cited by
46
References
183
Citations by year
2026: 6 · 2025: 13 · 2024: 10 · 2023: 9 · 2022: 8
FWCI
1.78
Type
journal article
Language
en
Open access
Licence
Locations
  • Plants (publishedVersion, cc-by)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
Consejo Nacional de Ciencia y Tecnología
Topics
  • Health Sciences › Medicine › Dermatology › Skin Protection and Aging
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Molecular Biology › Bioactive natural compounds
  • Health Sciences › Medicine › Biochemistry › Phytochemicals and Antioxidant Activities
Keywords
plant secondary metabolites, ultraviolet radiation, photoprotection, photodamaged skin, photoaging, skin cancer prevention, phenolic compounds, alkaloids, carotenoids, Mexican flora, sunscreen ingredients

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