Cited by 215Natural Antidiabetic Agents StudiesNutrition, Genetics, and DiseaseNutritional Studies and Diet

Functional foods-based diet as a novel dietary approach for management of type 2 diabetes and its complications: A review

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Mirmiran, Parvin·2014·World Journal of Diabetes

Abstract

Type 2 diabetes is a complicated metabolic disorder with both short- and long-term undesirable complications. In recent years, there has been growing evidence that functional foods and their bioactive compounds, due to their biological properties, may be used as complementary treatment for type 2 diabetes mellitus. In this review, we have highlighted various functional foods as missing part of medical nutrition therapy in diabetic patients. Several in vitro, animal models and some human studies, have demonstrated that functional foods and nutraceuticals may improve postprandial hyperglycemia and adipose tissue metabolism modulate carbohydrate and lipid metabolism. Functional foods may also improve dyslipidemia and insulin resistance, and attenuate oxidative stress and inflammatory processes and subsequently could prevent the development of long-term diabetes complications including cardiovascular disease, neuropathy, nephropathy and retinopathy. In conclusion available data indicate that a functional foods-based diet may be a novel and comprehensive dietary approach for management of type 2 diabetes.

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  • Functional foods attempt to improve health by incorporating bioactive compounds that may alter lipid, vascular, and other metabolic pathways, microbiome composition and function, and digestive and inflammatory systems.

    “Similar to dietary supplements, functional foods attempt to improve health by incorporating bioactive compounds that may alter lipid, vascular, and other metabolic pathways, microbiome composition and function, and digestive and inflammatory systems.114-121”

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Research works printed but not linked: 2

  1. Fatema K, Habib B, Afza N, Ali L. Glycemic, non-esterified fatty acid (NEFA) and insulinemic responses to watermelon and apple in type 2 diabetic subjects. Asia Pac J Clin Nutr 2003; 12 Suppl: S53 [PMID: 15023673]
  2. Josef B, Raj S. Pharmacognostic and phytochemical proper- ties of Ficus carica Linn: An overview. Int J Pharma Tech Res 2011; 3: 8-12 134

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Authors
Mirmiran, P.
Affiliations
National Nutrition and Food Technology Research Institute (IR)
Corresponding author
Mirmiran, Parvin
Venue
World Journal of Diabetes
Published
2014
Volume
5
Issue
3
Pages
267
ISSN
1948-9358 (ISSN-L)
OpenAlex
W2021722567
Cited by
215
References
208
Citations by year
2026: 9 · 2025: 8 · 2024: 18 · 2023: 21 · 2022: 26 · 2021: 35 · 2020: 20 · 2019: 19 · 2018: 13 · 2017: 15 · 2016: 15 · 2015: 14 · 2014: 2
FWCI
2.44
Type
journal article
Language
en
Open access
Licence
cc-by-nc
Locations
  • World Journal of Diabetes (publishedVersion, cc-by-nc)
  • Europe PMC (PubMed Central) (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
Topics
  • Health Sciences › Medicine › Endocrinology, Diabetes and Metabolism › Natural Antidiabetic Agents Studies
  • Life Sciences › Biochemistry, Genetics and Molecular Biology › Genetics › Nutrition, Genetics, and Disease
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Nutritional Studies and Diet
Keywords
type 2 diabetes, functional foods, nutraceuticals, medical nutrition therapy, postprandial hyperglycemia, insulin resistance, dyslipidemia, oxidative stress, inflammation, diabetes complications, cardiovascular disease, diabetic neuropathy, diabetic nephropathy, diabetic retinopathy, carbohydrate metabolism, lipid metabolism

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