THE EFFECTS OF PLASMODIUM FALCIPARUM AND P. VIVAX INFECTIONS ON PLACENTAL HISTOPATHOLOGY IN AN AREA OF LOW MALARIA TRANSMISSION
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Placental histopathology was studied in a cohort of 204 women living in an area of low Plasmodium falciparum and P. vivax malaria transmission. Detection of malaria antenatally was active, by weekly peripheral blood smears, and all infections were treated. Significant histopathologic placental malaria changes (increased malaria pigment, cytotrophoblastic prominence, and presence of parasites) were found only in a minority of women who had P. falciparum infections in pregnancy. These changes were significantly more frequent in women with evidence of peripheral blood infection close to delivery and only in these cases were placental inflammatory cells increased. Antenatal P. vivax infection was associated only with the presence of malaria pigment in the placenta. All placental infections diagnosed by blood smear and 32.4% (12 of 37) diagnosed by histopathology were associated with patent peripheral parasitemia. This study indicates that prompt treatment of peripheral parasitemias during pregnancy limits placental pathology. The effect on birth weight reduction may not result from irreversible placental changes but from the acute insult of infection. These findings emphasize the importance of treating malaria in pregnancy promptly with effective antimalarial drugs.
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Vivax parasites do not frequently express variant surface antigens, at the basis of placenta sequestration, so that this does not occur frequently.
“Vivax parasites do not frequently express variant surface antigens, at the basis of placenta sequestration, so that this does not occur frequently.81”
From Malaria in pregnancy. (2013) · cites this paper as [81]
Women with malaria detected by weekly antenatal screenings and effective treatment often have no histological changes at delivery.
“women with malaria detected by weekly ante natal screenings and effective treatment often have no histological changes at delivery [56,57].”
From Diagnosing malaria in pregnancy: An update (2012) · cites this paper as [56]
Cites
The Pathology of the Human Placenta
Benirschke, K., & Driscoll, S. G. (1967) · Springer eBooks · doi:10.1007/978-1-4612-9809-0 · Cited by 2,123 · see citing works
Adherence of <i>Plasmodium falciparum</i> to Chondroitin Sulfate A in the Human Placenta
Fried, M., & Duffy, P. E. (1996) · Science · doi:10.1126/science.272.5267.1502 · Cited by 1,108 · see citing works
The Impact of Placental Malaria on Gestational Age and Birth Weight
Menendez, C., Ordi, J., Ismail, M. R., Ventura, P. J., Aponte, J. J., Kahigwa, E., Font, F., & Alonso, P. L. (2000) · The Journal of Infectious Diseases · doi:10.1086/315449 · Cited by 467 · see citing works
Parise, M. E., Ayisi, J., Nahlen, B. L., Schultz, L. J., Roberts, J. M., Misore, A. O., Muga, R., Oloo, A. J., & Steketee, R. W. (1998) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.1998.59.813 · Cited by 387 · see citing works
Effects of Plasmodium vivax malaria in pregnancy.
Nosten, F., McGready, R., Simpson, J., Thwai, K., Balkan, S., Cho, T., Hkirijaroen, L., Looareesuwan, S., & White, N. (1999) · The Lancet · doi:10.1016/s0140-6736(98)09247-2 · Cited by 381 · see citing works
Self-citationMalaria during pregnancy: A priority area of malaria research and control
Menéndez, C. (1995) · Parasitology Today · doi:10.1016/0169-4758(95)80151-0 · Cited by 322 · see citing works
Malaria in African Infants and Children in Southern Nigeria
Bruce-Chwatt, L. J. (1952) · Annals of Tropical Medicine and Parasitology · doi:10.1080/00034983.1952.11685522 · Cited by 299 · see citing works
Malaria during pregnancy in an area of unstable endemicity.
Nosten, F., ter Kuile, F., Maelankirri, L., Decludt, B., & White, N. J. (1991) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/0035-9203(91)90205-d · Cited by 294 · cited 3× · see citing works
“falciparum, and maternal anemia is a common consequence.(4) Similar adverse effects have been reported in P.”
BackgroundResultInfluentialSelf-citationROGERSON, S. J., POLLINA, E., GETACHEW, A., TADESSE, E., LEMA, V. M., & MOLYNEUX, M. E. (2003) · The American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2003.68.1.0680115 · Cited by 275 · see citing works
Massive chronic intervillositis of the placenta associated with malaria infection
Ordi, J., Ismail, M. R., Ventura, P. J., Kahigwa, E., Hirt, R., Cardesa, A., Alonso, P. L., & Menendez, C. (1998) · The American Journal of Surgical Pathology · doi:10.1097/00000478-199808000-00011 · Cited by 265 · see citing works
Placental pathologic changes in malaria. A histologic and ultrastructural study.
Walter, P. R., GARIN, Y. J. F., & Blot, P. (1982) · PubMed · Cited by 253 · see citing works
The epidemiology of malaria in a Karen population on the western border of Thailand.
Luxemburger, C., Thwai, K. L., White, N. J., Webster, H. K., Kyle, D. E., Maelankirri, L., Chongsuphajaisiddhi, T., & Nosten, F. (1996) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/s0035-9203(96)90102-9 · Cited by 233 · see citing works
Self-citationPlacental malaria. I. Pathological classification
BULMER, J. N., RASHEED, F. N., FRANCIS, N., MORRISON, L., & GREENWOOD, B. M. (1993) · Histopathology · doi:10.1111/j.1365-2559.1993.tb00110.x · Cited by 222 · see citing works
QUININE AND SEVERE FALCIPARUM MALARIA IN LATE PREGNANCY
Looareesuwan, S., White, N. J., Karbwang, J., Turner, R. C., Phillips, R. E., Kietinun, S., Rackow, C., & Warrell, D. A. (1985) · The Lancet · doi:10.1016/s0140-6736(85)90056-x · Cited by 208 · see citing works
Self-citationMoormann, A. M., Sullivan, A. D., Rochford, R. A., Chensue, S. W., Bock, P. J., Nyirenda, T. E., & Meshnick, S. R. (1999) · The Journal of Infectious Diseases · doi:10.1086/315135 · Cited by 208 · see citing works
Self-citationShulman, C. E., Marshall, T., Dorman, E. K., Bulmer, J. N., Cutts, F., Peshu, N., & Marsh, K. (2001) · Tropical Medicine & International Health · doi:10.1046/j.1365-3156.2001.00786.x · Cited by 182 · see citing works
Rogerson, S. J., Chaluluka, E., Kanjala, M. K., Mkundika, P., Mhango, C. G., & Molyneux, M. E. (2000) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/s0035-9203(00)90083-x · Cited by 172 · see citing works
Epidemiology of malaria in pregnancy in central India.
(1999) · Europe PMC (PubMed Central) · Cited by 140 · see citing works
The pharmacokinetics of atovaquone and proguanil in pregnant women with acute falciparum malaria
McGready, R., Stepniewska, K., Edstein, M. D., Cho, T., Gilveray, G., Looareesuwan, S., White, N. J., & Nosten, F. (2003) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-003-0652-9 · Cited by 138 · see citing works
Self-citationPregnancy and use of oral contraceptives reduces the biotransformation of proguanil to cycloguanil
McGready, R. M., Stepniewska, K., Seaton, E. D., Cho, T., Cho, D., Ginsberg, A., Edstein, M. D., Ashley, E. A., Looareesuwan, S., White, N. J., et al. (2003) · European Journal of Clinical Pharmacology · doi:10.1007/s00228-003-0651-x · Cited by 136 · see citing works
Self-citationMaternal malaria and parasite adhesion
Fried, M., & Duffy, P. E. (1998) · Journal of Molecular Medicine · doi:10.1007/s001090050205 · Cited by 117 · see citing works
Placental malaria. II. A semi‐quantitative investigation of the pathological features
Bulmer, J. N., Rasheed, F. N., Morrison, L., FRANCIS, N., & Greenwood, B. M. (1993) · Histopathology · doi:10.1111/j.1365-2559.1993.tb00111.x · Cited by 115 · see citing works
McGready, R., Brockman, A., Cho, T., Cho, D., van Vugt, M., Luxemburger, C., Chongsuphajaisiddhi, T., White, N. J., & Nosten, F. (2000) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/s0035-9203(00)90235-9 · Cited by 110 · see citing works
Self-citationPlasmodial pigmentation of placenta and outcome of pregnancy in West African mothers.
Watkinson, M., & Rushton, D. I. (1983) · BMJ · doi:10.1136/bmj.287.6387.251 · Cited by 102 · see citing works
Low birth-weight and malarial infection of the placenta.
Jelliffe, E. F. P. (1968) · PubMed · Cited by 92 · see citing works
The sequestration of Plasmodium falciparum infected erythrocytes in the placenta
Bray, R. S., & Sinden, R. E. (1979) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/0035-9203(79)90028-2 · Cited by 85 · see citing works
Shulman, Shulman, Dorman, Dorman, Talisuna, Lowe, Lowe, Nevill, Nevill, Snow, et al. (1998) · Tropical Medicine & International Health · doi:10.1046/j.1365-3156.1998.00214.x · Cited by 83 · see citing works
Mefloquine antimalarial prophylaxis in pregnancy: dose finding and pharmacokinetic study.
Nosten, F. H., Karbwang, J., White, N. J., Honeymoon, Bangchang, K. N., BUNNAG, D., & Harinasuta, T. (1990) · British Journal of Clinical Pharmacology · doi:10.1111/j.1365-2125.1990.tb03746.x · Cited by 79 · see citing works
Self-citationGestational Malaria: Assessment of its Consequences on Fetal Growth
Meuris, S., Piko, B. B., Eerens, P., Vanbellinghen, A.-M., Dramaix, M., & Hennart, P. (1993) · The American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.1993.48.603 · Cited by 71 · cited 3× · see citing works
“3] Number weekly consults, median 19 [1–33] 21 [4–33] 21 [3–36] 22 [1–34] Number of malaria infections detected and treated 1 [1–4] PV 2 [1–4] Total 3 [1–7]† 0 antenatally, median PM 1 [1] PF 1 [1–3] PV 1 [1–6] Mixed 1 [1] Proportion with at least 1 symptomatic malaria episode 63.”
BackgroundThe placenta in malaria with special reference to reticulo-endothelial immunity
Garnhám, P. C. C. (1938) · Transactions of the Royal Society of Tropical Medicine and Hygiene · doi:10.1016/s0035-9203(38)90094-x · Cited by 63 · see citing works
Malaria in Pregnancy : Deadly Parasite, Susceptible Host
Duffy, P. E., & Fried, M. (2002) · Cited by 60 · see citing works
Leopardi, O., Naughten, W., Salvia, L., Colecchia, M., Matteelli, A., Zucchi, A., Shein, A., Muchi, J. A., Carosi, G., & Ghione, M. (1996) · Pathology - Research and Practice · doi:10.1016/s0344-0338(96)80068-9 · Cited by 57 · see citing works
Plasmodium coatneyi in the rhesus monkey (Macaca mulatta) as a model of malaria in pregnancy.
Davison, B. B., Cogswell, F. B., Baskin, G. B., Falkenstein, K. P., Henson, E. W., Tarantal, A. F., & Krogstad, D. J. (1998) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.1998.59.189 · Cited by 50 · see citing works
Self-citationMaternal malaria: Plasmodium falciparum sequestration in the placenta
Andrews, K. T., & Lanzer, M. (2002) · Parasitology Research · doi:10.1007/s00436-002-0624-5 · Cited by 48 · see citing works
Placental malaria and pregnancy outcome
Ibhanesebhor, S. E., & Okolo, A. A. (1992) · International Journal of Gynecology & Obstetrics · doi:10.1016/0020-7292(92)90324-c · Cited by 47 · see citing works
Davison, B. B., Cogswell, F. B., Baskin, G. B., Falkenstein, K. P., Henson, E. W., & Krogstad, D. J. (2000) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2000.63.158 · Cited by 44 · see citing works
Self-citationA study of the consequences of malarial infection in pregnant women and their infants.
Brabin, B. J., Maxwell, S. L., Chimsuku, L., Verhoeff, F. H., Hj, V. D. K., Broadhead, R., Kazembe, P., & Thomas, A. (1993) · PubMed · Cited by 24 · see citing works
Immunity to Malaria During Pregnancy: Different Host, Different Parasite
Duffy, P. E. (2001) · CRC Press eBooks · doi:10.3109/9780203302255-11 · Cited by 23 · see citing works
Malaria prevention during pregnancy in unstable transmission areas: the highlands of Madagascar
Cot, M., Brutus, L., Pinell, V., Ramaroson, H. J. V., Raveloson, A., Rabeson, D., & Rakotonjanabelo, A. (2002) · Tropical Medicine & International Health · doi:10.1046/j.1365-3156.2002.00897.x · Cited by 22 · see citing works
Effects of placental malaria on mothers and neonates from Zaire
Anagnos, D., Lanoie, L. O., Palmieri, J. R., Ziefer, A., & Connor, D. H. (1986) · Parasitology Research · doi:10.1007/bf00927734 · Cited by 22 · see citing works
Gestational age of the newborn: A clinical manual
Dubowitz, L. M. S., & Dubowitz, V. (1977) · Cited by 18 · see citing works
Malaria placental infection with massive chronic intervillositis in a gravida 4 woman
Nebuloni, M., Pallotti, F., Polizzotti, G., Pellegrinelli, A., Tosi, D., & Giordano, F. (2001) · Human Pathology · doi:10.1053/hupa.2001.27603 · Cited by 17 · see citing works
Malarial placental infection and low birth weight babies.
Kaushik, A., Sharma, V. K., Sadhna, Kumar, R., & Mitra, R. (1992) · PubMed · Cited by 14 · see citing works
Procop, G. W., Jessen, R., Hyde, S., & Scheck, D. N. (2001) · Journal of Perinatology · doi:10.1038/sj.jp.7200465 · Cited by 13 · see citing works
[Malaria infection during childbirth and in newborns in Bécédi (Ivory Coast)].
Bachschmid, I., Soro, B., Coulibaly, A., Philippe, E., Kingston, L., Kien, T., & Rey, J. L. (1991) · PubMed · Cited by 5 · see citing works
[Plasmodial indices and malarial placentopathy in 299 parturients in Central Africa].
Testa, J., Awodabon, J., Lagarde, N., Olivier, T., & Delmont, J. P. (1990) · PubMed · Cited by 4 · see citing works
Flagged first, then by citations
Cited by
Sorted by citations
Epidemiology and burden of malaria in pregnancy
Desai, M., ter Kuile, F. O., Nosten, F., McGready, R., Asamoa, K., Brabin, B., & Newman, R. D. (2007) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(07)70021-x · Cited by 1,432 · see citing works
Self-citationVivax Malaria: Neglected and Not Benign
Price, R. N., Tjitra, E., Guerra, C. A., Yeung, S., White, N. J., & Anstey, N. M. (2007) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2007.77.79 · Cited by 840 · see citing works
Self-citationMalaria in pregnancy: pathogenesis and immunity
Rogerson, S. J., Hviid, L., Duffy, P. E., Leke, R. F., & Taylor, D. W. (2007) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(07)70022-1 · Cited by 628 · see citing works
(2014) · Tropical Medicine & International Health · doi:10.1111/tmi.12313_2 · Cited by 542 · see citing works
The pathophysiology of vivax malaria
Anstey, N. M., Russell, B., Yeo, T. W., & Price, R. N. (2009) · Trends in Parasitology · doi:10.1016/j.pt.2009.02.003 · Cited by 434 · see citing works
The Sick Placenta—The Role of Malaria
Brabin, B. J., Romagosa, C., Abdelgalil, S., Menéndez, C., Verhoeff, F. H., McGready, R. M., Fletcher, K. A., Owens, S., d'Alessandro, U., Nosten, F. H., et al. (2004) · Placenta · doi:10.1016/j.placenta.2003.10.019 · Cited by 374 · see citing works
Self-citationChallenges for malaria elimination in Brazil
Ferreira, M. U., & Castro, M. C. (2016) · Malaria Journal · doi:10.1186/s12936-016-1335-1 · Cited by 230 · see citing works
Anstey, N. M., Douglas, N. M., Poespoprodjo, J. R., & Price, R. N. (2012) · Advances in Parasitology/Advances in parasitology · doi:10.1016/b978-0-12-397900-1.00003-7 · Cited by 219 · see citing works
Finken, M. J. J., van der Steen, M., Smeets, C. C. J., Walenkamp, M. J. E., de Bruin, C., Hokken-Koelega, A., & Wit, J. M. (2018) · Endocrine Reviews · doi:10.1210/er.2018-00083 · Cited by 220 · see citing works
Cox‐Singh, J., Hiu, J., Lucas, S. B., Divis, P. C. S., Zulkarnaen, M., Chandran, P. A., Wong, K. T., Adem, P. V., Zaki, S. R., Singh, B. B., et al. (2010) · Malaria Journal · doi:10.1186/1475-2875-9-10 · Cited by 209 · see citing works
Anstey, N. M., Handojo, T., PAIN, M. C. F., Kenangalem, E., Tjitra, E., Price, R. N., & Maguire, G. P. (2007) · The Journal of Infectious Diseases · doi:10.1086/510756 · Cited by 202 · see citing works
Malaria in Pregnancy: Linking Immunity and Pathogenesis to Prevention
Rogerson, S. J., Mwapasa, V., & Meshnick, S. R. (2007) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.77.6.suppl.14 · Cited by 183 · see citing works
Self-citationMalaria in pregnancy and the endemicity spectrum: what can we learn?
Nosten, F. H., Rogerson, S. J., Beeson, J. G., McGready, R. M., Mutabingwa, T. K., & Brabin, B. J. (2004) · Trends in Parasitology · doi:10.1016/j.pt.2004.06.007 · Cited by 184 · see citing works
Self-citationMalaria in pregnancy in the Asia-Pacific region
Rijken, M. J., McGready, R., Boel, M. E., Poespoprodjo, R., Singh, N., Syafruddin, D., Rogerson, S., & Nosten, F. (2012) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(11)70315-2 · Cited by 181 · see citing works
Self-citationTakem, E. N., & D'Alessandro, U. (2013) · Mediterranean Journal of Hematology and Infectious Diseases · doi:10.4084/mjhid.2013.010 · Cited by 185 · see citing works
Poespoprodjo, J. R., Fobia, W., Kenangalem, E., Lampah, D. A., Warikar, N., Seal, A., McGready, R., Sugiarto, P., Tjitra, E., Anstey, N. M., et al. (2008) · Clinical Infectious Diseases · doi:10.1086/586743 · Cited by 148 · see citing works
Self-citationKattenberg, J. H., Ochodo, E. A., Boer, K. R., Schallig, H. D., Mens, P. F., & Leeflang, M. M. (2011) · Malaria Journal · doi:10.1186/1475-2875-10-321 · Cited by 138 · see citing works
Moore, K. A., Simpson, J. A., Wiladphaingern, J., Min, A. M., Pimanpanarak, M., Paw, M. K., Raksuansak, J., Pukrittayakamee, S., Fowkes, F. J. I., White, N. J., et al. (2017) · BMC Medicine · doi:10.1186/s12916-017-0877-6 · Cited by 111 · see citing works
Self-citationEpidemiology, drug resistance, and pathophysiology of <i>Plasmodium vivax</i> malaria
Gowda, D., Dayananda, K., & Achur, R. (2018) · Journal of Vector Borne Diseases · doi:10.4103/0972-9062.234620 · Cited by 111 · see citing works
Mayor, A., Serra-Casas, E., Bardají, A., Sanz, S., Puyol, L., Cisteró, P., Sigauque, B., Mandomando, I., Aponte, J. J., Alonso, P. L., et al. (2009) · Malaria Journal · doi:10.1186/1475-2875-8-9 · Cited by 105 · see citing works
New Insights into Acquisition, Boosting, and Longevity of Immunity to Malaria in Pregnant Women
Fowkes, F. J., McGready, R., Cross, N. J., Hommel, M., Simpson, J. A., Elliott, S. R., Richards, J. S., Lackovic, K., Viladpai-Nguen, J., Narum, D., et al. (2012) · The Journal of Infectious Diseases · doi:10.1093/infdis/jis566 · Cited by 101 · see citing works
Self-citationMuehlenbachs, A., Fried, M., McGready, R., Harrington, W. E., Mutabingwa, T. K., Nosten, F., & Duffy, P. E. (2010) · The Journal of Infectious Diseases · doi:10.1086/656723 · Cited by 100 · see citing works
Self-citationThe impact of maternal malaria on newborns
Hartman, T. K., Rogerson, S. J., & Fischer, P. R. (2010) · Annals of Tropical Paediatrics · doi:10.1179/146532810x12858955921032 · Cited by 95 · see citing works
Piola, P., Nabasumba, C., Turyakira, E., Dhorda, M., Lindegardh, N., Nyehangane, D., Snounou, G., Ashley, E. A., McGready, R., Nosten, F., et al. (2010) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(10)70202-4 · Cited by 99 · see citing works
Self-citationThe Immunology and Pathogenesis of Malaria During Pregnancy
Beeson, J. G., & Duffy, P. E. (2005) · Current topics in microbiology and immunology · doi:10.1007/3-540-29967-x_6 · Cited by 94 · see citing works
Cottrell, G., Mary, J., Barro, D., & Cot, M. (2007) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2007.76.849 · Cited by 93 · see citing works
Uneke, C. J. (2007) · PubMed Central · Cited by 92 · see citing works
Case management of malaria in pregnancy
Nosten, F. H., McGready, R. M., & Mutabingwa, T. K. (2007) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(07)70023-3 · Cited by 88 · see citing works
Self-citationPlasmodium vivax Adherence to Placental Glycosaminoglycans
Chotivanich, K., Udomsangpetch, R., Suwanarusk, R., Pukrittayakamee, S., Wilairatana, P., Beeson, J. G., Day, N. P. J., & White, N. J. (2012) · PLoS ONE · doi:10.1371/journal.pone.0034509 · Cited by 88 · see citing works
Self-citationLandis, S., Lokomba, V., Ananth, C. V., Atibu, J., Ryder, R. W., Hartmann, K. E., Thorp, J. M., Tshefu, A., & Meshnick, S. R. (2008) · Epidemiology and Infection · doi:10.1017/s0950268808000915 · Cited by 86 · see citing works
Self-citationFrom evidence to action? Challenges to policy change and programme delivery for malaria in pregnancy
Crawley, J., Hill, J., Yartey, J., Robalo, M., Serufilira, A., Ba-Nguz, A., Roman, E., Palmer, A., Asamoa, K., & Steketee, R. W. (2007) · The Lancet Infectious Diseases · doi:10.1016/s1473-3099(07)70026-9 · Cited by 84 · see citing works
Diagnosing malaria in pregnancy: An update
Fried, M., Muehlenbachs, A., & Duffy, P. E. (2012) · Expert Review of Anti-infective Therapy · doi:10.1586/eri.12.98 · Cited by 80 · see citing works
Clinical impact of vivax malaria: A collection review
Phyo, A. P., Dahal, P., Mayxay, M., & Ashley, E. A. (2022) · PLoS Medicine · doi:10.1371/journal.pmed.1003890 · Cited by 86 · see citing works
Placental Histopathological Changes Associated with Plasmodium vivax Infection during Pregnancy
Souza, R. M., Ataíde, R., Dombrowski, J. G., Ippólito, V., Aitken, E. H., Valle, S. N., Álvarez, J. M., Epiphânio, S., & Marinho, C. R. F. (2013) · PLoS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0002071 · Cited by 79 · see citing works
Briand, V., Cottrell, G., Massougbodji, A., & Cot, M. (2007) · Malaria Journal · doi:10.1186/1475-2875-6-160 · Cited by 72 · see citing works
Chaikitgosiyakul, S., Rijken, M. J., Muehlenbachs, A., Lee, S. J., Chaisri, U., Viriyavejakul, P., Turner, G. D., Pongponratn, E., Nosten, F., & McGready, R. (2014) · Malaria Journal · doi:10.1186/1475-2875-13-4 · Cited by 66 · see citing works
Self-citationVásquez, A. M., Medina, A. C., Tobón-Castaño, A., Posada, M., Tobón, G. J. V., Campillo, A., González, I. J., & Ding, X. C. (2018) · PLoS ONE · doi:10.1371/journal.pone.0201769 · Cited by 66 · see citing works
Kattenberg, J. H., Tahita, C. M., Versteeg, I. A. J., Tinto, H., Traoré‐Coulibaly, M., Schallig, H. D. F. H., & Mens, P. F. (2012) · Tropical Medicine & International Health · doi:10.1111/j.1365-3156.2012.02975.x · Cited by 63 · see citing works
Wilson, N. O., Ceesay, F. K., Obed, S. A., Adjei, A. A., Gyasi, R. K., Rodney, P., Ndjakani, Y., Anderson, W. A., Lucchi, N. W., & Stiles, J. K. (2011) · The American Society of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2011.10-0512 · Cited by 58 · see citing works
Pincelli, A., Neves, P. A. R., Lourenço, B. H., Corder, R. M., Malta, M. B., Sampaio-Silva, J., de Souza, R. M., Cardoso, M. A., Castro, M. C., Ferreira, M. U., et al. (2018) · The American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.18-0135 · Cited by 57 · see citing works
On the pathogenesis of Plasmodium vivax malaria: Perspectives from the Brazilian field
Costa, F. T. M., Lopes, S. C. P., Albrecht, L., Ataíde, R., Siqueira, A. M., de Souza, R. M., Russell, B., Rénia, L., Marinho, C. R. F., & Lacerda, M. (2012) · International Journal for Parasitology · doi:10.1016/j.ijpara.2012.08.007 · Cited by 56 · see citing works
Arango, E. M., Samuel, R., Agudelo, O. M., Carmona-Fonseca, J., Maestre, A., & Yanow, S. K. (2013) · The American Society of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.12-0669 · Cited by 55 · see citing works
Sohail, M., Shakeel, S., Kumari, S., Bharti, A., Zahid, F., Anwar, S., Singh, K. P., Mazahirul, I., Sharma, A. K., Lata, S., et al. (2015) · BioMed Research International · doi:10.1155/2015/740512 · Cited by 54 · see citing works
Placental Infection With Plasmodium vivax: A Histopathological and Molecular Study
Mayor, A., Bardají, A., Felger, I., King, C. L., Cisteró, P., Dobaño, C., Stanisic, D. I., Siba, P., Wahlgren, M., del Portillo, H., et al. (2012) · The Journal of Infectious Diseases · doi:10.1093/infdis/jis614 · Cited by 53 · see citing works
Malaria-Induced Murine Pregnancy Failure: Distinct Roles for IFN-γ and TNF
Poovassery, J. S., Sarr, D., Smith, G., Nagy, T., & Moore, J. M. (2009) · The Journal of Immunology · doi:10.4049/jimmunol.0901669 · Cited by 53 · see citing works
Of mice and women: rodent models of placental malaria
Hviid, L., Marinho, C. R. F., Staalsøe, T., & Penha‐Gonçalves, C. (2010) · Trends in Parasitology · doi:10.1016/j.pt.2010.04.010 · Cited by 52 · see citing works
Malaria and immunity during pregnancy and postpartum: a tale of two species
McLean, A. R. D., Ataíde, R., Simpson, J. A., Beeson, J. G., & Fowkes, F. J. I. (2015) · Parasitology · doi:10.1017/s0031182015000074 · Cited by 55 · see citing works
Plasmodium vivax Biology: Insights Provided by Genomics, Transcriptomics and Proteomics
Bourgard, C., Albrecht, L., Kayano, A. C. A. V., Sunnerhagen, P., & Costa, F. T. M. (2018) · Frontiers in Cellular and Infection Microbiology · doi:10.3389/fcimb.2018.00034 · Cited by 50 · see citing works
Parekh, F. K., Davison, B. B., Gamboa, D., Hernandez, J., & Branch, O. H. (2010) · The American Society of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2010.09-0445 · Cited by 49 · see citing works
Self-citationPregnancy-associated malaria: Parasite binding, natural immunity and vaccine development
Gamain, B., Smith, J. D., Viebig, N. K., Gysin, J., & Scherf, A. (2006) · International Journal for Parasitology · doi:10.1016/j.ijpara.2006.11.011 · Cited by 49 · see citing works
Noninvasive Ventilation in Plasmodium vivax Related ALI/ARDS
Agarwal, R., Nath, A., & Gupta, D. (2007) · Internal Medicine · doi:10.2169/internalmedicine.46.0401 · Cited by 47 · see citing works
Kattenberg, J. H., Tahita, M. C., Versteeg, I. A. J., Tinto, H., Traoré‐Coulibaly, M., D’Alessandro, U., Schallig, H. D. F. H., & Mens, P. F. (2012) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2012.12-0125 · Cited by 44 · see citing works
Thrombocytopaenia in pregnant women with malaria on the Thai-Burmese border
Tan, S. O., McGready, R. M., Zwang, J., Pimanpanarak, M., Sriprawat, K., Thwai, K. L., Moo, Y., Ashley, E. A., Edwards, B., Singhasivanon, P., et al. (2008) · Malaria Journal · doi:10.1186/1475-2875-7-209 · Cited by 44 · see citing works
Self-citationDombrowski, J. G., Barateiro, A., Peixoto, E. P. M., Barros, A. B. C. D. S., Souza, R. M. D., Clark, T. G., Campino, S., Wrenger, C., Wunderlich, G., Palmisano, G., et al. (2021) · PLOS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0009390 · Cited by 42 · see citing works
Okoyo, C. O., Githinji, E. K., Muia, R. W., Masaku, J., Mwai, J., Nyandieka, L. N., Munga, S., Njenga, S. M., & Kanyi, H. M. (2021) · PLoS ONE · doi:10.1371/journal.pone.0257276 · Cited by 45 · see citing works
Carmona-Fonseca, J., Arango, E., & Maestre, A. (2013) · The American Society of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.12-0363 · Cited by 42 · see citing works
Highly Effective Therapy for Maternal Malaria Associated With a Lower Risk of Vertical Transmission
Poespoprodjo, J. R., Fobia, W., Kenangalem, E., Hasanuddin, A., Sugiarto, P., Tjitra, E., Anstey, N. M., & Price, R. N. (2011) · The Journal of Infectious Diseases · doi:10.1093/infdis/jir558 · Cited by 42 · see citing works
Is human malarial coma caused, or merely deepened, by sequestration?
Clark, I. A., & Alleva, L. M. (2009) · Trends in Parasitology · doi:10.1016/j.pt.2009.04.003 · Cited by 41 · see citing works
Vásquez, A. M., Zuluaga, L. M., Tobón-Castaño, A., Posada, M., Tobón, G. J. V., González, I. J., Campillo, A., & Ding, X. C. (2018) · Malaria Journal · doi:10.1186/s12936-018-2403-5 · Cited by 41 · see citing works
IS MALARIAL PLACENTAL INFECTION RELATED TO PERIPHERAL INFECTION AT ANY TIME OF PREGNANCY?
Cottrell, G., Mary, J., Barro, D., & Cot, M. (2005) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2005.73.1112 · Cited by 39 · see citing works
Malaria in Pregnancy Interacts with and Alters the Angiogenic Profiles of the Placenta
Ataíde, R., Murillo, O., Dombrowski, J. G., Souza, R. M., Lima, F. A., Lima, G. F. M. C., Hristov, A. D., Valle, S. C. N., Di Santi, S. M., Epiphanio, S., et al. (2015) · PLOS Neglected Tropical Diseases · doi:10.1371/journal.pntd.0003824 · Cited by 37 · see citing works
Ahmed, R., Singh, N., ter Kuile, F. O., Bharti, P. K., Singh, P. P., Desai, M., Udhayakumar, V., & Terlouw, D. J. (2014) · Malaria Journal · doi:10.1186/1475-2875-13-232 · Cited by 35 · see citing works
Muehlenbachs, A., Nabasumba, C., McGready, R., Turyakira, E., Tumwebaze, B., Dhorda, M., Nyehangane, D., Nalusaji, A., Nosten, F., Guerin, P. J., et al. (2012) · Malaria Journal · doi:10.1186/1475-2875-11-150 · Cited by 35 · see citing works
Self-citation<i>Plasmodium vivax</i>Malaria during Pregnancy, Bolivia
Brutus, L., Santalla, J., Schneider, D., Avila, J. C., & Deloron, P. (2013) · Emerging Infectious Diseases · doi:10.3201/eid1910.130308 · Cited by 34 · see citing works
Saito, M., Gilder, M. E., Nosten, F. H., McGready, R. M., & Guerin, P. J. (2017) · Malaria Journal · doi:10.1186/s12936-017-2135-y · Cited by 35 · see citing works
Self-citationSingh, N., Singh, M. P., Wylie, B. J., Hussain, M. Z., Yeboah‐Antwi, K., Shekhar, C., Sabin, L., Desai, M. R., Udhayakumar, V., & Hamer, D. H. (2012) · Malaria Journal · doi:10.1186/1475-2875-11-274 · Cited by 36 · see citing works
Thanapongpichat, S., McGready, R., Luxemburger, C., Day, N. P., White, N. J., Nosten, F., Snounou, G., & Imwong, M. (2013) · Malaria Journal · doi:10.1186/1475-2875-12-275 · Cited by 32 · see citing works
Self-citationHIGH PREVALENCE OF PLACENTAL MALARIA AND LOW BIRTH WEIGHT IN SAHELIAN PERIURBAN AREA
Sarr, D., Marrama, L., Gaye, A., Dangou, J.-M., Niang, M., Mercereau‐Puijalon, O., Hesran, J. L., & Jambou, R. (2006) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2006.75.171 · Cited by 31 · see citing works
Treatment and prevention of malaria in pregnancy and newborn
Coll, O., Menéndez, C., Botet, F., Dayal, R., Carbonell-Estrany, A. T. W. P. I. W. X., Weisman, L. E., Anceschi, M. M., Greenough, A., Gibss, R. S., & Ville, Y. G. (2008) · Journal of Perinatal Medicine · doi:10.1515/jpm.2008.002 · Cited by 29 · see citing works
Boström, S., Schmiegelow, C., Abed, U. A., Minja, D. T. R., Lusingu, J., Brinkmann, V., Honkpéhèdji, Y. J., Loembé, M. M., Adégnika, A. A., Mordmüller, B. G., et al. (2017) · Parasite Immunology · doi:10.1111/pim.12433 · Cited by 28 · see citing works
Malaria in pregnancy: diagnosing infection and identifying fetal risk
Conroy, A. L., McDonald, C. R., & Kain, K. C. (2012) · Expert Review of Anti-infective Therapy · doi:10.1586/eri.12.123 · Cited by 27 · see citing works
Maestre, A., & Carmona‐Fonseca, J. (2014) · The Journal of Infection in Developing Countries · doi:10.3855/jidc.3777 · Cited by 27 · see citing works
Effects of Vivax Malaria Acquired Before 20 Weeks of Pregnancy on Subsequent Changes in Fetal Growth
Machado Filho, A. C., da Costa, E. P., da Costa, E. P., Reis, I. S., Fernandes, E. A. C., Paim, B. V., & Martinez-Espinosa, F. E. (2014) · The American Society of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.13-0285 · Cited by 26 · see citing works
Gavina, K., Gnidehou, S., Arango, E., Hamel-Martineau, C., Mitran, C., Agudelo, O., Lopez, C., Karidio, A., Banman, S., Carmona-Fonseca, J., et al. (2018) · Infection and Immunity · doi:10.1128/iai.00797-17 · Cited by 26 · see citing works
Complement activation: a critical mediator of adverse fetal outcomes in placental malaria?
Conroy, A. L., McDonald, C. R., Silver, K. L., Liles, W. C., & Kain, K. C. (2011) · Trends in Parasitology · doi:10.1016/j.pt.2011.02.005 · Cited by 26 · see citing works
Corder, R. M., de Lima, A. C. P., Khoury, D. S., Docken, S. S., Davenport, M. P., & Ferreira, M. U. (2020) · PLoS neglected tropical diseases · doi:10.1371/journal.pntd.0008526 · Cited by 26 · see citing works
Costa, F. T. M., Avril, M., Nogueira, P. A., & Gysin, J. (2006) · Brazilian Journal of Medical and Biological Research · doi:10.1590/s0100-879x2006001200003 · Cited by 29 · see citing works
McLean, A. R. D., Stanisic, D. I., McGready, R. M., Chotivanich, K., Clapham, C., Baiwog, F., Pimanpanarak, M., Siba, P., Müeller, I., King, C. L., et al. (2017) · PLoS ONE · doi:10.1371/journal.pone.0186577 · Cited by 25 · see citing works
Self-citationCharnaud, S. C., McGready, R., Herten-Crabb, A., Powell, R., Guy, A., Langer, C., Richards, J. S., Gilson, P. R., Chotivanich, K., Tsuboi, T., et al. (2016) · Scientific Reports · doi:10.1038/srep20859 · Cited by 23 · see citing works
Self-citationGenesis of placental sequestration in malaria and possible targets for drugs for placental malaria
Clark, R. L. (2019) · Birth Defects Research · doi:10.1002/bdr2.1496 · Cited by 27 · see citing works
Saito, M., Mansoor, R., Kennon, K., Anvikar, A. R., Ashley, E. A., Chandramohan, D., Cohee, L. M., D’Alessandro, U., Genton, B., Gilder, M. E., et al. (2020) · BMC Medicine · doi:10.1186/s12916-020-01592-z · Cited by 24 · see citing works
Self-citationPlasmodium vivax malaria: An unusual presentation
Kujur, R., Kasliwal, P., & Rao, M. S. (2009) · Indian Journal of Critical Care Medicine · doi:10.4103/0972-5229.56059 · Cited by 22 · see citing works
Davison, B. B., Kaack, M. B., Rogers, L. B., Rasmussen, K. K., Rasmussen, T., Henson, E. W., Henson, M. C., Parekh, F. K., & Krogstad, D. J. (2006) · The Journal of Infectious Diseases · doi:10.1086/504694 · Cited by 21 · see citing works
Self-citationApparent Relapse of Imported Plasmodium ovale Malaria in a Pregnant Woman
Coldren, R. L., Jongsakul, K., Vayakornvichit, S., Noedl, H., & Fukudas, M. M. (2007) · American Journal of Tropical Medicine and Hygiene · doi:10.4269/ajtmh.2007.77.992 · Cited by 21 · see citing works
Harrington, W. E., Moore, K. A., Min, A. M., Gilder, M. E., Tun, N. W., Paw, M. K., Wiladphaingern, J., Proux, S., Chotivanich, K., Rijken, M. J., et al. (2021) · BMC Medicine · doi:10.1186/s12916-021-01960-3 · Cited by 23 · see citing works
Self-citationBôtto-Menezes, C., Silva dos Santos, M. C., Lopes Simplício, J., Menezes de Medeiros, J., Barroso Gomes, K. C., de Carvalho Costa, I. C., Batista-Silva, E., Teixeira do Nascimento, C., da Silva Chagas, E. C., Jardim Sardinha, J. F., et al. (2015) · PLOS ONE · doi:10.1371/journal.pone.0144399 · Cited by 20 · see citing works
Laochan, N., Zaloumis, S. G., Imwong, M., Lek‐Uthai, U., Brockman, A., Sriprawat, K., Wiladphaingern, J., White, N. J., Nosten, F. H., & McGready, R. M. (2015) · Malaria Journal · doi:10.1186/s12936-015-0745-9 · Cited by 20 · see citing works
Self-citationter Kuile, F. O., & Rogerson, S. J. (2008) · Clinical Infectious Diseases · doi:10.1086/586744 · Cited by 19 · see citing works
Submicroscopic and multiple plasmodium falciparum infections in pregnant Sudanese women
Omer, S., Khalil, E., Ali, H., & Sharief, A. (2011) · North American Journal of Medical Sciences · doi:10.4297/najms.2011.3137 · Cited by 19 · see citing works
Kane, E. G., & Taylor-Robinson, A. W. (2011) · Malaria Research and Treatment · doi:10.4061/2011/764845 · Cited by 19 · see citing works
Nwaefuna, E. K., Afoakwah, R., Orish, V. N., Egyir-Yawson, A., & Boampong, J. N. (2015) · Journal of Parasitology Research · doi:10.1155/2015/959427 · Cited by 17 · see citing works
Burger, R. J., Visser, B. J., Grobusch, M. P., & van Vugt, M. (2016) · Malaria Journal · doi:10.1186/s12936-016-1160-6 · Cited by 18 · see citing works
Malaria in pregnancy: the relevance of animal models for vaccine development
Doritchamou, J., Teo, A., Fried, M., & Duffy, P. E. (2017) · Lab Animal · doi:10.1038/laban.1349 · Cited by 17 · see citing works
Oyibo, W. A., & Agomo, C. O. (2010) · Maternal and Child Health Journal · doi:10.1007/s10995-010-0608-5 · Cited by 18 · see citing works
Singh, P. P., Lucchi, N. W., Blackstock, A. J., Udhayakumar, V., & Singh, N. (2012) · PLoS ONE · doi:10.1371/journal.pone.0051678 · Cited by 16 · see citing works
Prediction of prolonged mechanical ventilation for intensive care unit patients: A cohort study
Sanabria, Á., Gómez, X., Vega, N. V., Domínguez, L. C., & Osorio, C. (2013) · Colombia medica · doi:10.25100/cm.v44i3.1285 · Cited by 16 · see citing works
Treatment and prevention of malaria in pregnancy: opportunities and challenges
Rogerson, S. J., & Menéndez, C. (2006) · Expert Review of Anti-infective Therapy · doi:10.1586/14787210.4.4.687 · Cited by 16 · see citing works
Brock, M. F., Miranda, A. E., Bôtto-Menezes, C., Leão, J. R. D. T., & Martínez-Espinosa, F. E. (2015) · Malaria Journal · doi:10.1186/s12936-015-0627-1 · Cited by 15 · see citing works
Age-modified factors associated with placental malaria in rural Burkina Faso
Bihoun, B., Zango, S. H., Traoré‐Coulibaly, M., Valéa, I., Ravinetto, R., Geertruyden, J. V., D’Alessandro, U., Tinto, H., & Robert, A. R. (2022) · BMC Pregnancy and Childbirth · doi:10.1186/s12884-022-04568-4 · Cited by 15 · see citing works
Davison, B. B., Kaack, M. B., Rogers, L. B., Rasmussen, K. K., Rasmussen, T., Henson, E. W., Montenegro, S., Henson, M. C., Mzwaek, F., & Krogstad, D. J. (2005) · The Journal of Infectious Diseases · doi:10.1086/430004 · Cited by 13 · see citing works
Self-citation
- Authors
- McGREADY, R., DAVISON, B. B., STEPNIEWSKA, K., CHO, T., SHEE, H., BROCKMAN, A., UDOMSANGPETCH, R., LOOAREESUWAN, S., WHITE, N. J., MESHNICK, S. R., & NOSTEN, F.
- Affiliations
- University of North Carolina at Chapel Hill (US)
- Shoklo Malaria Research Unit, Mae Sot, Thailand; Faculty of Tropical Medicine, and Faculty of Science, Mahidol University, Bangkok, Thailand; Centre for Clinical Vaccinology and Tropical Medicine, Churchill Hospital, Oxford, United Kingdom; Division of Comparative Pathology, Tulane National Primate Research Center, Covington, Louisiana; Departments of Epidemiology and Microbiology and Immunology, University of North Carolina, Chapel Hill, North Carolina
- Venue
- The American Journal of Tropical Medicine and Hygiene
- Published
- 2004-04
- Volume
- 70
- Issue
- 4
- Pages
- 398-407
- ISSN
- 0002-9637 (ISSN-L)
- OpenAlex
- W2102655747
- Cited by
- 170
- References
- 46
- Citations by year
- 2026: 2 · 2025: 1 · 2023: 3 · 2022: 6 · 2021: 9 · 2020: 17 · 2019: 6 · 2018: 9 · 2017: 7 · 2016: 4 · 2015: 10 · 2014: 7 · 2013: 17 · 2012: 16
- FWCI
- 9.21
- Type
- journal article
- Language
- en
- Open access
- green
- cdr.lib.unc.edu
- Locations
- American Journal of Tropical Medicine and Hygiene (publishedVersion)
- PubMed (publishedVersion)
- Carolina Digital Repository (University of North Carolina at Chapel Hill) (submittedVersion)
- UNC Libraries
- Funders
- National Institutes of Health (5r01ai042400-05)
- National Institute of Allergy and Infectious Diseases (5R01AI42400)
- National Center for Research Resources (P51-RR-00164, P51RR000164)
- Topics
- Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
- Health Sciences › Medicine › Obstetrics and Gynecology › Pregnancy and preeclampsia studies
- Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Global Maternal and Child Health
- Keywords
- Plasmodium falciparum, Plasmodium vivax, placental malaria, placental pathology, malaria in pregnancy, hemozoin, placental inflammation, low malaria transmission
- MeSH terms
- Adolescent, Adult, Animals, Antimalarials, Female, Fetal Blood, Histocytochemistry, Humans, Infant, Low Birth Weight, Infant, Newborn, Placenta, Plasmodium falciparum, Plasmodium vivax, Pregnancy, Prospective Studies, Thailand, Cohort Studies, Pregnancy Complications, Parasitic, Malaria, Falciparum, Malaria, Vivax, Parasitemia
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