Cited by 58Malaria Research and ControlGlobal Maternal and Child HealthHemoglobinopathies and Related Disorders

Intermittent Preventive Treatment with Sulfadoxine-Pyrimethamine against Malaria and Anemia in Pregnant Women

Open access
Wilson, Nana O., Ceesay, Fatou K., Obed, Samuel A., Adjei, Andrew A., Gyasi, Richard K., Rodney, Patricia, Ndjakani, Yassa, Anderson, Winston A. +2 more·2011·The American Society of Tropical Medicine and Hygiene

Abstract

The effectiveness of intermittent preventive treatment during pregnancy with sulfadoxine-pyrimethamine (IPTp-SP) against malaria and anemia is unclear because of the spread of SP-resistant Plasmodium falciparum. This study evaluates the effectiveness of IPTp-SP among pregnant women attending the antenatal clinic at Korle-Bu Teaching Hospital in Accra, Ghana. A cross-sectional study comparing malaria and anemia prevalence among pregnant women using IPTp-SP with non-IPTp-SP users was conducted during June–August 2009. A total of 363 pregnant women (202 of IPTp users and 161 non-IPTp users) were recruited. A total of 15.3% of IPTp users had malaria compared with 44.7% of non-IPTp users (P < 0.001). A total of 58.4% of non-IPTp users were anemic compared with 22.8% of IPTp users (P < 0.001). When we controlled for other variables, the difference in the prevalence of malaria (odds ratio = 0.18, 95% confidence interval = 0.08–0.37) and anemia (odds ratio = 0.20, 95% confidence interval = 0.12–0.34) remained significant. The recommended IPTp-SP regimen is useful in preventing malaria and anemia among pregnant women in Ghana.

Integrity signals

Registry

Crossref · 10.4269/ajtmh.2011.10-0512

Cites

80 of 80 references verified0 citation errors · 0 not checkable

Statistics

Recomputing p-values needs the paper’s full text.

Claims the paper makes

We couldn’t retrieve this paper’s full text, so its claims and self-check weren’t run. The registry and citation checks still apply.

Claims other papers make about this one

Each is checked against this paper’s own text: does it say what the citing paper says it does?

  • Preventing malaria infection by intermittent preventive treatment during pregnancy reduces the risk of anaemia.

    “Preventing malaria infection by intermittent preventive treatment during pregnancy (IPTp) reduces the risk of anaemia.27,37–38”

    From Malaria in pregnancy. (2013) · cites this paper as [27]

Cites

Flagged first, then by citations

3 of the 83 references couldn’t be matched to a known paper.

Cited by

Sorted by citations

Authors
Wilson, N. O., Ceesay, F. K., Obed, S. A., Adjei, A. A., Gyasi, R. K., Rodney, P., Ndjakani, Y., Anderson, W. A., Lucchi, N. W., & Stiles, J. K.
Affiliations
Morehouse School of Medicine (US)
Venue
The American Society of Tropical Medicine and Hygiene
Published
2011-07-01
Volume
85
Issue
1
Pages
12-21
ISSN
  • 0002-9637 (ISSN-L)
  • 1476-1645
OpenAlex
W2137587975
Cited by
58
References
83
Citations by year
2026: 2 · 2025: 1 · 2024: 4 · 2023: 4 · 2022: 5 · 2021: 4 · 2020: 5 · 2019: 4 · 2018: 4 · 2017: 3 · 2016: 2 · 2015: 9 · 2014: 3 · 2013: 4 · 2012: 4
FWCI
3.46
Type
journal article
Language
en
Open access
Locations
  • American Journal of Tropical Medicine and Hygiene (publishedVersion)
  • PubMed Central (publishedVersion)
  • PubMed (publishedVersion)
  • Digital Howard (Howard University) (submittedVersion)
Funders
  • National Institutes of Health (5s06gm008248-23)
  • National Institute of General Medical Sciences (SO6-GM08248, R25GM058268, S06 GM-008248)
  • Fogarty International Center (R21TW006804)
  • National Center for Research Resources (RR 03034, G12RR003034, R25RR017694)
  • National Institute on Minority Health and Health Disparities (S21MD000101)
Topics
  • Health Sciences › Medicine › Public Health, Environmental and Occupational Health › Malaria Research and Control
  • Health Sciences › Medicine › Pediatrics, Perinatology and Child Health › Global Maternal and Child Health
  • Health Sciences › Medicine › Genetics › Hemoglobinopathies and Related Disorders
Keywords
intermittent preventive treatment, sulfadoxine-pyrimethamine, IPTp-SP, malaria in pregnancy, anemia in pregnancy, Plasmodium falciparum, sulfonamide resistance, prenatal care, pregnant women, malaria prevention, Ghana
MeSH terms
Adolescent, Adult, Anemia, Antimalarials, Drug Combinations, Female, Humans, Malaria, Pregnancy, Pyrimethamine, Surveys and Questionnaires, Sulfadoxine, Pregnancy Complications, Parasitic, Young Adult

About these checks

Registry, retraction, Cites and statistics results are computed, not judged, with one exception: a printed reference that no index lists is read once by a model before it counts as a citation error. Claims are extracted by a model and kept only when their quote appears verbatim in the text; each cited source is then checked, with a model’s help, for whether it says what the claim relies on. Those verdicts can be wrong — read the claim’s quote and the cited source before relying on one.

Statistics and arithmetic are recomputed, not judged.

Confidence bands are shown only for fields calibrated on our annotated test set. None is calibrated yet, so no band is shown.

What counts as a claim ›How we measure confidence ›How we check this ›

Are you an author, or do you see a problem with this page? Request a review