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2025 Seoul Consensus on Clinical Practice Guidelines for Irritable Bowel Syndrome

Choi, Yonghoon, Youn, Young Hoon, Kang, Seung Joo, Shin, Jeong Eun, Cho, Young Sin, Jung, Yoon Suk, Shin, Seung Yong, Huh, Cheal Wung, Lee, Yoo Jin, Koo, Hoon Sup, Nam, Kwangwoo, Lee, Hong Sub, Kim, Dong Hyun, Park, Ye Hyun, Kim, Min Cheol, Song, Hyo Yeop, Yoon, Sung-Hoon, Lee, Sang Yeol, Choi, Miyoung, Park, Moo-In, Sung, In-Kyung, the Korean Society of Neurogastroenterology and Motility·2025·Journal of Neurogastroenterology and Motility

DOI 10.5056/jnm25007

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Methodological quality (risk of bias) assessment tools for primary and secondary medical studies: what are they and which is better?
Ma, L.-L., Wang, Y.-Y., Yang, Z.-H., Huang, D., Weng, H., & Zeng, X.-T. (2020) · Military Medical Research · doi:10.1186/s40779-020-00238-8 · Cited by 1,648
Neurotransmitter modulation by the gut microbiota
Strandwitz, P. (2018) · Brain Research · doi:10.1016/j.brainres.2018.03.015 · Cited by 1,527
Rifaximin Therapy for Patients with Irritable Bowel Syndrome without Constipation
Pimentel, M., Lembo, A., Chey, W. D., Zakko, S., Ringel, Y., Yu, J., Mareya, S. M., Shaw, A. L., Bortey, E., & Forbes, W. P. (2011) · New England Journal of Medicine · doi:10.1056/nejmoa1004409 · Cited by 1,036
ACG Clinical Guideline: Management of Irritable Bowel Syndrome
Lacy, B. E., Pimentel, M., Brenner, D. M., Chey, W. D., Keefer, L. A., Long, M. D., & Moshiree, B. (2021) · American Journal of Gastroenterology · doi:10.14309/ajg.0000000000001036 · Cited by 893 · cited 8×
“17 IBS can arise within months following bacterial, viral, and parasitic GI infections, as the reported risk is 3.5-4.2 times higher in exposed individuals compared to non-exposed individuals, 80-82 although the prevalence of post-infectious IBS varies.”
Influential
What is new in Rome IV
Schmulson, M. J., & Drossman, D. A. (2017) · Journal of Neurogastroenterology and Motility · doi:10.5056/jnm16214 · Cited by 788
Gut Microbiota in Patients With Irritable Bowel Syndrome—A Systematic Review
Pittayanon, R., Lau, J. T., Yuan, Y., Leontiadis, G. I., Tse, F., Surette, M., & Moayyedi, P. (2019) · Gastroenterology · doi:10.1053/j.gastro.2019.03.049 · Cited by 719
Self-Reported Food-Related Gastrointestinal Symptoms in IBS Are Common and Associated With More Severe Symptoms and Reduced Quality of Life
Böhn, L., Störsrud, S., Törnblom, H., Bengtsson, U., & Simrén, M. (2013) · American Journal of Gastroenterology · doi:10.1038/ajg.2013.105 · Cited by 655
Cognitive-behavioral therapy versus education and desipramine versus placebo for moderate to severe functional bowel disorders 1 1This study was registered with ClinicalTrials.gov (trial registry no. NCT00006157).
Drossman, D. A., Toner, B. B., Whitehead, W. E., Diamant, N. E., Dalton, C. B., Duncan, S., Emmott, S., Proffitt, V., Akman, D., Frusciante, K., et al. (2003) · Gastroenterology · doi:10.1016/s0016-5085(03)00669-3 · Cited by 614
British Society of Gastroenterology guidelines on the management of irritable bowel syndrome
Vasant, D. H., Paine, P. A., Black, C. J., Houghton, L. A., Everitt, H. A., Corsetti, M., Agrawal, A., Aziz, I., Farmer, A. D., Eugenicos, M. P., et al. (2021) · Gut · doi:10.1136/gutjnl-2021-324598 · Cited by 592 · cited 8×
“Statement 16.”
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A placebo-controlled trial of prucalopride for severe chronic constipation
Camilleri, M., Kerstens, R., Rykx, A., & Vandeplassche, L. (2008) · New England Journal of Medicine · doi:10.1056/nejmoa0800670 · Cited by 576

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Plant-Derived Treatments for IBS: Clinical Outcomes, Mechanistic Insights, and Their Position in International Guidelines
Pastras, P., Aggeletopoulou, I., Bali, M., & Triantos, C. (2026) · Nutrients · doi:10.3390/nu18020183 · Cited by 1

Authors: Choi, Y., Youn, Y. H., Kang, S. J., Shin, J. E., Cho, Y. S., Jung, Y. S., Shin, S. Y., Huh, C. W., Lee, Y. J., Koo, H. S., Nam, K., Lee, H. S., Kim, D. H., Park, Y. H., Kim, M. C., Song, H. Y., Yoon, S.-H., Lee, S. Y., Choi, M., Park, M.-I., Sung, I.-K., & the Korean Society of Neurogastroenterology and Motility
Affiliations: Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Gyeonngi-do, Korea
Department of Internal Medicine, Gangnam Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
Department of Internal Medicine, Seoul National University Hospital Healthcare System Gangnam Center, Seoul, Korea
Department of Internal Medicine, Dankook University College of Medicine, Cheonan, Chungcheongnam-do, Korea
Department of Internal Medicine, Soonchunhyang University Cheonan Hospital, Cheonan, Chungcheongnam-do, Korea
Department of Internal Medicine, Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul, Korea
Department of Internal Medicine, Chung-Ang University College of Medicine, Seoul, Korea
Department of Internal Medicine, Yongin Severance Hospital, Yonsei University College of Medicine, Seoul, Korea
Department of Internal Medicine, Keimyung University School of Medicine, Daegu, Korea
Department of Internal Medicine, Konyang University Hospital, Daejeon, Korea
Department of Internal Medicine, Inje University Busan Paik Hospital, Busan, Korea
Department of Internal Medicine, Chonnam National University Hospital, Chonnam National University Medical School, Gwangju, Korea
Department of Internal Medicine, Ewha Womans University College of Medicine, Seoul, Korea
Department of Internal Medicine, Yeungnam University Hospital, Daegu, Korea
Department of Internal Medicine and Digestive Disease Research Institute, Wonkwang University School of Medicine, Iksan, Jeonbuk State, Korea
Department of Psychiatry, Wonkwang University Hospital, Iksan, Jeonbuk State, Korea
Division of Healthcare Technology Assessment Research, National Evidence-Based Healthcare Collaborating Agency, Seoul, Korea
Department of Internal Medicine, Kosin University College of Medicine, Busan, Korea
Department of Internal Medicine, Konkuk University School of Medicine, Seoul, Korea
ORCID: Choi, Yonghoon
Youn, Young Hoon
Kang, Seung Joo
Shin, Jeong Eun
Cho, Young Sin
Jung, Yoon Suk
Shin, Seung Yong
Huh, Cheal Wung
Lee, Yoo Jin
Koo, Hoon Sup
Nam, Kwangwoo
Lee, Hong Sub
Kim, Dong Hyun
Park, Ye Hyun
Kim, Min Cheol
Song, Hyo Yeop
Yoon, Sung-Hoon
Lee, Sang Yeol
Choi, Miyoung
Park, Moo-In
Sung, In-Kyung
Venue: Journal of Neurogastroenterology and Motility
Publisher: The Korean Society of Neurogastroenterology and Motility
Published: 2025-04-30
Volume: 31
Issue: 2
Pages: 133-169
ISSN: 2093-0879
2093-0887
DOI: 10.5056/jnm25007
Cited by: 33
References: 58
Language: en
Licence: creativecommons.org/licenses/by-nc/4.0 (tdm)

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2025 Seoul Consensus on Clinical Practice Guidelines for Irritable Bowel Syndrome

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