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Cited by 558

The DOI matches its Crossref record; 4 of the 4 references it cites were found in a registry or an index.

Sleep Duration and Sleep Quality in Relation to 12-Year Cardiovascular Disease Incidence: The MORGEN Study

Open access
Hoevenaar-Blom, Marieke P., Spijkerman, Annemieke M.W., Kromhout, Daan, van den Berg, Julia F., Verschuren, W.M. Monique·2011·Sleep
DOI 10.5665/sleep.1382
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Abstract

STUDY OBJECTIVES: We studied sleep duration and sleep quality in relation to cardiovascular disease (CVD) incidence. DESIGN/SETTING: Dutch population-based cohort study. PARTICIPANTS: 20,432 men and women aged 20-65 and with no history of CVD. INTERVENTIONS: N/A. MEASUREMENTS: Sleep duration and sleep quality were assessed by a self-administered questionnaire. Morbidity data, vital status, and causes of death were obtained through linkage with several national registries. Hazard ratios (HRs) and 95% confidence intervals (95% CIs) were calculated using Cox proportional hazards models. RESULTS: During 10-15 years of follow-up, 1,486 CVD and 1,148 coronary heart disease (CHD) events occurred. Short sleepers (≤ 6 h) had a 15% higher risk of total CVD (HR: 1.15; 95%CI: 1.00-1.32) and a 23% higher risk of CHD (HR: 1.23 [1.04-1.45]) compared to normal sleepers (7 h) after adjustment for all confounders. Additional adjustment for intermediate biological risk factors attenuated these relative risks to 1.11 (0.97-1.27) for total CVD and to 1.19 (1.00-1.40) for CHD. Short sleepers with poor sleep quality had a 63% higher risk of CVD (HR: 1.63 [1.21-2.19]) and a 79% higher risk of CHD incidence (HR: 1.79 [1.24-2.58]) compared to normal sleepers with good sleep quality, after adjustments for all confounders. We observed no associations between long sleep duration (≥ 9 h) and CVD or CHD incidence. CONCLUSIONS: Short sleepers, especially those with poor sleep quality, have an increased risk of total CVD and CHD incidence. Future investigations should not only focus on sleep duration, but should also take sleep quality into account.

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Metadata

Authors
Hoevenaar-Blom, M. P., Spijkerman, A. M. W., Kromhout, D., van den Berg, J. F., & Verschuren, W. M. M.
Venue
Sleep
Publisher
Oxford University Press (OUP)
Published
2011-11
Volume
34
Issue
11
Pages
1487-1492
ISSN
  • 0161-8105 (ISSN-L)
  • 1550-9109
DOI
10.5665/sleep.1382
OpenAlex
W2127097910
Cited by
558
References
4
FWCI
34.00
Type
journal article
Language
en
Open access
green

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