Cited by 229Sleep and related disordersSleep and Work-Related FatigueCircadian rhythm and melatonin

Sleep duration versus sleep insufficiency as predictors of cardiometabolic health outcomes

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Altman, Nicole G., Izci-Balserak, Bilgay, Schopfer, Elizabeth, Jackson, Nicholas, Rattanaumpawan, Pinyo, Gehrman, Philip R., Patel, Nirav P., Grandner, Michael A.·2012·Sleep Medicine

Abstract

Objective The objective of the present study was to investigate the relationship between sleep insufficiency and sleep duration, particularly regarding negative cardiometabolic health outcomes already considered to be affected by reduced sleep time.Methods A total of N=30,934 participants from the 2009 Behavioural Risk Factor Surveillance System (BRFSS) answered questions about their sleep duration as well as subjective feelings of sleep insufficiency. Outcomes included body mass index (BMI), obesity (BMI ≥ 30kgm(-2)) and history of hypertension, diabetes, hypercholesterolaemia, heart attack and stroke. Linear and logistic regression models examined whether cardiometabolic outcomes were associated with (1) sleep duration alone, (2) sleep insufficiency alone and (3) the combined effect of sleep duration and sleep insufficiency.Results Results indicated that, when examined alone, sleep duration <5h (versus 7h) was related to BMI (B=2.716, p<0.01), obesity (B=2.080, p<0.000001), diabetes (B=3.162, p<0.000001), hypertension (B=2.703, p<0.000001), hypercholesterolaemia (B=1.922, p<0.00001), heart attack (B=4.704, p<0.000001) and stroke (B=4.558, p<0.000001), and sleep insufficiency (days per week, continuous) was related to BMI (B=0.181, p<0.01), obesity (B=1.061, p<0.000001) and hypercholesterolaemia (B=1.025, p<0.01). All of these relationships remained significant after adjustment for covariates, except for diabetes and sleep duration. Also, after adjustment, a significant relationship between insufficient sleep and hypertension emerged (B=1.039, p<0.001). When evaluated together, after adjustment for covariates, significant relationships remained between sleep duration <5h (versus 7h) and BMI (B=1.266, p<0.05), obesity (B=1.389, p<0.05), hypertension (B=1.555, p<0.01), heart attack (B=2.513, p<0.01) and stroke (B=1.807, p<0.05). It should be noted that relationships between sleep duration >9h (versus 7h) were seen for heart attack (B=1.863, p<0.001) and stroke (B=1.816, p<0.01). In these models, sleep insufficiency was associated with hypercholesterolaemia (B=1.031, p<0.01) and hypertension (B=1.027, p<0.05).Conclusions These analyses show that both sleep duration and insufficiency are related to cardiometabolic health outcomes, and that when evaluated together, both variables demonstrate unique effects.

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Crossref · 10.1016/j.sleep.2012.08.005

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Authors
Altman, N. G., Izci-Balserak, B., Schopfer, E., Jackson, N., Rattanaumpawan, P., Gehrman, P. R., Patel, N. P., & Grandner, M. A.
Affiliations
  • University of Pennsylvania (US)
  • Reading Hospital (US)
Corresponding author
Grandner, Michael A.
Venue
Sleep Medicine
Publisher
Elsevier BV
Published
2012-12
Volume
13
Issue
10
Pages
1261-1270
ISSN
1389-9457 (ISSN-L)
OpenAlex
W2024997148
Cited by
229
References
72
Citations by year
2026: 5 · 2025: 12 · 2024: 4 · 2023: 27 · 2022: 15 · 2021: 23 · 2020: 14 · 2019: 15 · 2018: 15 · 2017: 18 · 2016: 24 · 2015: 22 · 2014: 26 · 2013: 8
FWCI
24.00
Type
journal article
Language
en
Open access
Locations
  • Sleep Medicine (publishedVersion)
  • PubMed (publishedVersion)
  • Europe PMC (PubMed Central) (acceptedVersion)
  • PubMed Central (acceptedVersion)
Funders
  • National Heart, Lung, and Blood Institute (T32HL007713, K23HL110216)
  • National Institute of Nursing Research (K99NR013187)
  • National Institute of Environmental Health Sciences (R21ES022931)
Topics
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and related disorders
  • Social Sciences › Psychology › Experimental and Cognitive Psychology › Sleep and Work-Related Fatigue
  • Life Sciences › Neuroscience › Endocrine and Autonomic Systems › Circadian rhythm and melatonin
Keywords
sleep duration, insufficient sleep, cardiometabolic health, obesity, body mass index, hypertension, diabetes mellitus, hypercholesterolemia, myocardial infarction, stroke, cardiovascular risk
MeSH terms
Cardiovascular Diseases, Diabetes Mellitus, Humans, Hypertension, Male, Middle Aged, Myocardial Infarction, Obesity, Risk Factors, Sleep, Sleep Wake Disorders, Body Mass Index, Linear Models, Logistic Models, Stroke, Behavioral Risk Factor Surveillance System

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