Sleep promotes cortical response potentiation following visual experience
Open accessAbstract
STUDY OBJECTIVES: Sleep has been hypothesized to globally reduce synaptic strength. However, recent findings suggest that in the context of learning and memory consolidation, sleep may promote synaptic potentiation. We tested the requirement for sleep in a naturally occurring form of experience-dependent synaptic potentiation in the adult mouse visual cortex (V1), which is initiated by patterned visual experience. DESIGN: Visual responses were recorded in individual V1 neurons before and after presentation of an oriented grating stimulus, and after subsequent sleep or sleep deprivation. MEASUREMENTS AND RESULTS: We find that V1 response potentiation-associated with a shift in orientation preference in favor of the presented stimulus-occurs only after sleep and only during the entrained circadian sleep phase, and is blocked by sleep deprivation. Induction of plasticity following stimulus presentation is associated with an increase in principal neuron firing in V1, which is present in all behavioral states and occurs regardless of time of day. Sleep dependent potentiation is proportional to phase-locking of neuronal activity with thalamocortical spindle oscillations. CONCLUSIONS: Our results suggest that sleep can promote cortical synaptic potentiation in vivo, and that this potentiation may be mediated by slow wave sleep spindles. CITATION: Aton SJ, Suresh A, Broussard C, Frank MG. Sleep promotes cortical response potentiation following visual experience.
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Sleep affects memory consolidation in the visual cortex.
“Work in the visual cortex also shows that sleep affects memory consolidation,80–82”
From Sleep Deprivation and Circadian Disruption (2015) · cites this paper as [82]
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Learning induces long-term potentiation in the hippocampus
Whitlock, J. R., Heynen, A. J., Shuler, M. G., & Bear, M. F. (2006) · Science · doi:10.1126/science.1128134 · Cited by 1,913 · see citing works
Huber, R., Felice Ghilardi, M., Massimini, M., & Tononi, G. (2004) · Nature · doi:10.1038/nature02663 · Cited by 1,854 · see citing works
Coordinated memory replay in the visual cortex and hippocampus during sleep
Ji, D., & Wilson, M. A. (2007) · Nature Neuroscience · doi:10.1038/nn1825 · Cited by 1,669 · see citing works
Sleep and synaptic homeostasis: a hypothesis
Tononi, G., & Cirelli, C. (2003) · Brain Research Bulletin · doi:10.1016/j.brainresbull.2003.09.004 · Cited by 1,217 · see citing works
Vyazovskiy, V. V., Cirelli, C., Pfister-Genskow, M., Faraguna, U., & Tononi, G. (2008) · Nature Neuroscience · doi:10.1038/nn2035 · Cited by 837 · see citing works
Cortical firing and sleep homeostasis
Vyazovskiy, V. V., Olcese, U., Lazimy, Y. M., Faraguna, U., Esser, S. K., Williams, J. C., Cirelli, C., & Tononi, G. (2009) · Neuron · doi:10.1016/j.neuron.2009.08.024 · Cited by 740 · see citing works
Extensive and divergent effects of sleep and wakefulness on brain gene expression
Cirelli, C., Gutierrez, C. M., & Tononi, G. (2004) · Neuron · doi:10.1016/s0896-6273(03)00814-6 · Cited by 627 · see citing works
Fast-Forward Playback of Recent Memory Sequences in Prefrontal Cortex During Sleep
Euston, D. R., Tatsuno, M., & McNaughton, B. L. (2007) · Science · doi:10.1126/science.1148979 · Cited by 586 · see citing works
Daytime naps, motor memory consolidation and regionally specific sleep spindles
Nishida, M., & Walker, M. P. (2007) · PLoS ONE · doi:10.1371/journal.pone.0000341 · Cited by 531 · see citing works
Sleep deprivation impairs cAMP signalling in the hippocampus
Vecsey, C. G., Baillie, G. S., Jaganath, D., Havekes, R., Daniels, A., Wimmer, M., Huang, T., Brown, K. M., Li, X.-Y., Descalzi, G., et al. (2009) · Nature · doi:10.1038/nature08488 · Cited by 454 · see citing works
Nowak, L. G., Azouz, R., Sanchez-Vives, M. V., Gray, C. M., & McCormick, D. A. (2003) · Journal of Neurophysiology · doi:10.1152/jn.00580.2002 · Cited by 443 · see citing works
Instructive Effect of Visual Experience in Mouse Visual Cortex
Frenkel, M. Y., Sawtell, N. B., DIOGO, A. C. M., Yoon, B.-J., Neve, R. L., & Bear, M. F. (2006) · Neuron · doi:10.1016/j.neuron.2006.06.026 · Cited by 309 · see citing works
Sleep Oscillations in the Thalamocortical System Induce Long-Term Neuronal Plasticity
Chauvette, S., Seigneur, J., & Timofeev, I. (2012) · Neuron · doi:10.1016/j.neuron.2012.08.034 · Cited by 304 · see citing works
Mechanisms of sleep-dependent consolidation of cortical plasticity
Aton, S. J., Seibt, J., Dumoulin, M., Jha, S. K., Steinmetz, N., Coleman, T., Naidoo, N., & Frank, M. G. (2009) · Neuron · doi:10.1016/j.neuron.2009.01.007 · Cited by 244 · see citing works
Self-citationVisual Experience Induces Long-Term Potentiation in the Primary Visual Cortex
Cooke, S. F., & Bear, M. F. (2010) · Journal of Neuroscience · doi:10.1523/jneurosci.4333-10.2010 · Cited by 242 · see citing works
Fowler, M. J., Sullivan, M. J., & Ekstrand, B. R. (1973) · Science · doi:10.1126/science.179.4070.302 · Cited by 208 · see citing works
Hagewoud, R., Havekes, R., Novati, A., Keijser, J. N., van der Zee, E. A., & Meerlo, P. (2009) · Journal of Sleep Research · doi:10.1111/j.1365-2869.2009.00799.x · Cited by 187 · see citing works
Physiological properties of inhibitory interneurons in cat striate cortex
Azouz, R. (1997) · Cerebral Cortex · doi:10.1093/cercor/7.6.534 · Cited by 173 · see citing works
Ashton, H. (2010) · Reference Reviews · doi:10.1108/09504121011057851 · Cited by 133 · see citing works
Aton, S. J., Broussard, C., Dumoulin, M., Seibt, J., Watson, A., Coleman, T., & Frank, M. G. (2013) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1208093110 · Cited by 113 · see citing works
Self-citationIntrinsic Neuronal Excitability Is Reversibly Altered by a Single Experience in Fear Conditioning
McKay, B. M., Matthews, E. A., Oliveira, F. A., & Disterhoft, J. F. (2009) · Journal of Neurophysiology · doi:10.1152/jn.00347.2009 · Cited by 85 · see citing works
CA1 hippocampal network activity changes during sleep-dependent memory consolidation
Ognjanovski, N., Maruyama, D., Lashner, N., Zochowski, M., & Aton, S. J. (2014) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2014.00061 · Cited by 81 · see citing works
Self-citationNere, A., Hashmi, A. G., Cirelli, C., & Tononi, G. (2013) · Frontiers in Neurology · doi:10.3389/fneur.2013.00143 · Cited by 79 · see citing works
Vecsey, C. G., Wimmer, M. E., Havekes, R., Park, A. J., Perron, I. J., Meerlo, P., & Abel, T. G. (2013) · SLEEP · doi:10.5665/sleep.2556 · Cited by 39 · see citing works
Set and setting: How behavioral state regulates sensory function and plasticity
Aton, S. J. (2013) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2013.06.007 · Cited by 36 · see citing works
Self-citationHashmi, A. G., Nere, A., & Tononi, G. (2013) · Frontiers in Neurology · doi:10.3389/fneur.2013.00148 · Cited by 29 · see citing works
Flagged first, then by citations
2 of the 28 references couldn’t be matched to a known paper.
Cited by
Sorted by citations
The Consolidation and Transformation of Memory
Dudai, Y., Karni, A., & Born, J. (2015) · Neuron · doi:10.1016/j.neuron.2015.09.004 · Cited by 741 · see citing works
Sleep spindles: mechanisms and functions
Fernandez, L. M. J., & Lüthi, A. (2020) · Physiological Reviews · doi:10.1152/physrev.00042.2018 · Cited by 716 · see citing works
Sleep function: Toward elucidating an enigma
Krueger, J. M., Frank, M. G., Wisor, J. P., & Roy, S. (2016) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2015.08.005 · Cited by 440 · see citing works
Self-citationSleep Deprivation and Circadian Disruption
McEwen, B. S., & Karatsoreos, I. N. (2015) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2014.11.007 · Cited by 338 · see citing works
Raven, F., Van der Zee, E. A., Meerlo, P., & Havekes, R. (2018) · Sleep Medicine Reviews · doi:10.1016/j.smrv.2017.05.002 · Cited by 331 · see citing works
Neuronal Firing Rate Homeostasis Is Inhibited by Sleep and Promoted by Wake
Hengen, K. B., Pacheco, A. T., McGregor, J. N., Hooser, S. D. V., & Turrigiano, G. G. (2016) · Cell · doi:10.1016/j.cell.2016.01.046 · Cited by 295 · see citing works
Ognjanovski, N., Schaeffer, S. M., Wu, J., Mofakham, S., Maruyama, D., Żochowski, M., & Aton, S. J. (2017) · Nature Communications · doi:10.1038/ncomms15039 · Cited by 221 · see citing works
Self-citationForm and function of sleep spindles across the lifespan
Clawson, B. C., Durkin, J., & Aton, S. J. (2016) · Neural Plasticity · doi:10.1155/2016/6936381 · Cited by 178 · see citing works
“Available data suggests that OSRP is mediated by LTP-like changes at TC synapses in layer 4 [79], and data from our lab have shown that these changes occur during sleep in the hours following visual experience [80, 81].”
BackgroundSelf-citationLinking Network Activity to Synaptic Plasticity during Sleep: Hypotheses and Recent Data
Puentes-Mestril, C., & Aton, S. J. (2017) · Frontiers in Neural Circuits · doi:10.3389/fncir.2017.00061 · Cited by 123 · see citing works
Self-citationSleep, clocks, and synaptic plasticity
Frank, M. G., & Cantera, R. (2014) · Trends in Neurosciences · doi:10.1016/j.tins.2014.06.005 · Cited by 118 · see citing works
Self-citationSleep slow oscillation and plasticity
Timofeev, I., & Chauvette, S. (2017) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2017.03.019 · Cited by 118 · see citing works
Primed to Sleep: The Dynamics of Synaptic Plasticity Across Brain States
Seibt, J., & Frank, M. G. (2019) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2019.00002 · Cited by 111 · see citing works
Self-citationFrank, M. G., & Heller, H. C. (2018) · Handbook of experimental pharmacology · doi:10.1007/164_2018_140 · Cited by 109 · see citing works
Self-citationSleep Promotes Downward Firing Rate Homeostasis
Pacheco, A. T., Bottorff, J., Gao, Y. B., & Turrigiano, G. G. (2020) · Neuron · doi:10.1016/j.neuron.2020.11.001 · Cited by 101 · see citing works
Slow Oscillations during Sleep Coordinate Interregional Communication in Cortical Networks
Cox, R., van Driel, J., de Boer, M., & Talamini, L. M. (2014) · Journal of Neuroscience · doi:10.1523/jneurosci.1953-14.2014 · Cited by 96 · see citing works
Durkin, J., Suresh, A. K., Colbath, J., Broussard, C., Wu, J., Żochowski, M., & Aton, S. J. (2017) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.1710613114 · Cited by 90 · see citing works
Self-citationHow rhythms of the sleeping brain tune memory and synaptic plasticity
Puentes-Mestril, C., Roach, J. P., Niethard, N., Żochowski, M., & Aton, S. J. (2019) · SLEEP · doi:10.1093/sleep/zsz095 · Cited by 90 · see citing works
Self-citationA mechanism for learning with sleep spindles
Peyrache, A., & Seibt, J. (2020) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2019.0230 · Cited by 89 · see citing works
CA1 hippocampal network activity changes during sleep-dependent memory consolidation
Ognjanovski, N., Maruyama, D., Lashner, N., Zochowski, M., & Aton, S. J. (2014) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2014.00061 · Cited by 81 · see citing works
Self-citationHuman REM sleep recalibrates neural activity in support of memory formation
Lendner, J. D., Niethard, N., Mander, B. A., van Schalkwijk, F. J., Schuh‐Hofer, S., Schmidt, H., Knight, R. T., Jan Born, A., Walker, M. P., Lin, J. J., et al. (2023) · Science Advances · doi:10.1126/sciadv.adj1895 · Cited by 79 · see citing works
Sleep and Synaptic Plasticity in the Developing and Adult Brain
Frank, M. G. (2014) · Current topics in behavioral neurosciences · doi:10.1007/7854_2014_305 · Cited by 78 · see citing works
Self-citationHippocampal Network Oscillations Rescue Memory Consolidation Deficits Caused by Sleep Loss
Ognjanovski, N., Broussard, C., Żochowski, M., & Aton, S. J. (2018) · Cerebral Cortex · doi:10.1093/cercor/bhy174 · Cited by 74 · see citing works
Self-citationClawson, B. C., Pickup, E. J., Ensing, A., Geneseo, L., Shaver, J., Gonzalez-Amoretti, J., Zhao, M., York, A. K., Kuhn, F. R., Swift, K., et al. (2021) · Nature Communications · doi:10.1038/s41467-021-21471-2 · Cited by 73 · see citing works
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McEwen, B. S., & Karatsoreos, I. N. (2022) · Sleep Medicine Clinics · doi:10.1016/j.jsmc.2022.03.005 · Cited by 70 · see citing works
Intracellular chloride regulation mediates local sleep pressure in the cortex
Alfonsa, H., Burman, R. J., Brodersen, P. J. N., Newey, S. E., Mahfooz, K., Yamagata, T., Panayi, M. C., Bannerman, D. M., Vyazovskiy, V. V., & Akerman, C. J. (2022) · Nature Neuroscience · doi:10.1038/s41593-022-01214-2 · Cited by 70 · see citing works
Durkin, J., & Aton, S. J. (2016) · Sleep · doi:10.5665/sleep.5338 · Cited by 68 · see citing works
Self-citationSleep Regulates Incubation of Cocaine Craving
Chen, B., Wang, Y., Liu, X., Liu, Z., Dong, Y., & Huang, Y. H. (2015) · Journal of Neuroscience · doi:10.1523/jneurosci.1065-15.2015 · Cited by 68 · see citing works
Sleep and Synaptic Homeostasis
Cirelli, C., & Tononi, G. (2014) · SLEEP · doi:10.5665/sleep.4348 · Cited by 67 · see citing works
Sleep restores an optimal computational regime in cortical networks
Xu, Y., Schneider, A. M., Weßel, R., & Hengen, K. B. (2024) · Nature Neuroscience · doi:10.1038/s41593-023-01536-9 · Cited by 59 · see citing works
Sleep, synaptic homeostasis and neuronal firing rates
Cirelli, C. (2017) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2017.03.016 · Cited by 58 · see citing works
Roles for sleep in memory: insights from the fly
Donlea, J. M. (2018) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2018.10.006 · Cited by 50 · see citing works
Modulating role of serotonergic signaling in sleep and memory
Vaseghi, S., Arjmandi-Rad, S., Eskandari, M., Ebrahimnejad, M., Kholghi, G., & Zarrindast, M. (2021) · Pharmacological Reports · doi:10.1007/s43440-021-00339-8 · Cited by 49 · see citing works
Drosophila as a Model to Study the Relationship Between Sleep, Plasticity, and Memory
Dissel, S. (2020) · Frontiers in Physiology · doi:10.3389/fphys.2020.00533 · Cited by 49 · see citing works
Weiss, J. T., & Donlea, J. M. (2022) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2021.777799 · Cited by 47 · see citing works
Sleep loss disrupts Arc expression in dentate gyrus neurons
Delorme, J. E., Kodoth, V., & Aton, S. J. (2018) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2018.04.006 · Cited by 47 · see citing works
Self-citationClawson, B. C., Durkin, J., Suresh, A. K., Pickup, E. J., Broussard, C., & Aton, S. J. (2018) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2018.00040 · Cited by 47 · see citing works
Self-citationFinnie, P. S. B., Komorowski, R. W., & Bear, M. F. (2021) · Current Biology · doi:10.1016/j.cub.2021.06.079 · Cited by 44 · see citing works
Hayden, D. J., Montgomery, D. P., Cooke, S. F., & Bear, M. F. (2021) · Journal of Neuroscience · doi:10.1523/jneurosci.0391-21.2021 · Cited by 43 · see citing works
A systematic and meta-analytic review of the impact of sleep restriction on memory formation
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del Cid‐Pellitero, E., Plavski, A., Mainville, L., & Jones, B. E. (2017) · Frontiers in Systems Neuroscience · doi:10.3389/fnsys.2017.00017 · Cited by 39 · see citing works
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Havekes, R., & Aton, S. J. (2020) · Trends in Neurosciences · doi:10.1016/j.tins.2020.03.010 · Cited by 39 · see citing works
Self-citationNeurocognitive Effects of Sleep Disruption in Children and Adolescents
Spruyt, K. (2020) · Child and Adolescent Psychiatric Clinics of North America · doi:10.1016/j.chc.2020.08.003 · Cited by 39 · see citing works
Memory corticalization triggered by REM sleep: mechanisms of cellular and systems consolidation
Almeida-Filho, D. G., Queiroz, C. M., & Ribeiro, S. (2018) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-018-2886-9 · Cited by 38 · see citing works
Calais, J. B., Ojopi, E. P. B., Morya, E., Sameshima, K., & Ribeiro, S. T. G. (2015) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2015.01.002 · Cited by 38 · see citing works
Experience and sleep-dependent synaptic plasticity: from structure to activity
Sun, L., Zhou, H., Cichon, J., & Yang, G. (2020) · Philosophical Transactions of the Royal Society B Biological Sciences · doi:10.1098/rstb.2019.0234 · Cited by 37 · see citing works
Plasticity in visual cortex is disrupted in a mouse model of tauopathy
Papanikolaou, A., Rodrigues, F. R., Holeniewska, J., Phillips, K. G., Saleem, A. B., & Solomon, S. G. (2022) · Communications Biology · doi:10.1038/s42003-022-03012-9 · Cited by 36 · see citing works
Visual recognition memory: a view from V1
Cooke, S. F., & Bear, M. F. (2015) · Current Opinion in Neurobiology · doi:10.1016/j.conb.2015.06.008 · Cited by 35 · see citing works
Ontogeny of Sleep and Its Functions in Infancy, Childhood, and Adolescence
Grigg-Damberger, M. M. (2016) · Springer eBooks · doi:10.1007/978-3-319-28640-2_1 · Cited by 34 · see citing works
Fang, Z., Smith, D., Albouy, G., King, B. R., Vien, C., Benali, H., Carrier, J., Doyon, J., & Fogel, S. M. (2021) · Frontiers in Aging Neuroscience · doi:10.3389/fnagi.2021.747358 · Cited by 31 · see citing works
Stability of neocortical synapses across sleep and wake states during the critical period in rats
Cary, B. A., & Turrigiano, G. G. (2021) · eLife · doi:10.7554/elife.66304 · Cited by 30 · see citing works
Distinct Laminar Requirements for NMDA Receptors in Experience-Dependent Visual Cortical Plasticity
Fong, M., Finnie, P. S. B., Kim, T.-K., Thomazeau, A., Kaplan, E. S., Cooke, S. F., & Bear, M. F. (2019) · Cerebral Cortex · doi:10.1093/cercor/bhz260 · Cited by 29 · see citing works
Stimulus-Selective Response Plasticity in Primary Visual Cortex: Progress and Puzzles
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Garrett, M., Groblewski, P. A., Piet, A. T., Ollerenshaw, D. R., Najafi, F., Yavorska, I., Amster, A., Bennett, C., Buice, M. A., Caldejon, S., et al. (2023) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2023.02.14.528085 · Cited by 29 · see citing works
Visual Sequences Drive Experience-Dependent Plasticity in Mouse Anterior Cingulate Cortex
Sidorov, M. S., Kim, H., Rougié, M., Williams, B., Siegel, J. J., Gavornik, J. P., & Philpot, B. D. (2020) · Cell Reports · doi:10.1016/j.celrep.2020.108152 · Cited by 28 · see citing works
Weiss, J. T., Blundell, M. Z., Singh, P., & Donlea, J. M. (2024) · Proceedings of the National Academy of Sciences · doi:10.1073/pnas.2312664121 · Cited by 25 · see citing works
Electrophysiological Signatures of Visual Recognition Memory across All Layers of Mouse V1
Hayden, D. J., Finnie, P. S. B., Thomazeau, A., Li, A. Y., Cooke, S. F., & Bear, M. F. (2023) · Journal of Neuroscience · doi:10.1523/jneurosci.0090-23.2023 · Cited by 21 · see citing works
Residual effects of emotion are reflected in enhanced visual activity after sleep
Bennion, K. A., Payne, J. D., & Kensinger, E. A. (2016) · Cognitive Affective & Behavioral Neuroscience · doi:10.3758/s13415-016-0479-3 · Cited by 21 · see citing works
Mechanisms of sleep and circadian ontogeny through the lens of neurodevelopmental disorders
Barone, I., Hawks-Mayer, H., & Lipton, J. O. (2019) · Neurobiology of Learning and Memory · doi:10.1016/j.nlm.2019.01.011 · Cited by 21 · see citing works
Gerashchenko, D., Schmidt, M. A., Zielinski, M. R., Moore, M. E., & Wisor, J. P. (2018) · Neuroscience · doi:10.1016/j.neuroscience.2018.02.006 · Cited by 20 · see citing works
How Sleep Shapes Thalamocortical Circuit Function in the Visual System
Durkin, J., & Aton, S. J. (2019) · Annual Review of Vision Science · doi:10.1146/annurev-vision-091718-014715 · Cited by 20 · see citing works
Self-citationKim, T.-K., Chaloner, F. A., Cooke, S. F., Harnett, M. T., & Bear, M. F. (2020) · Frontiers in Cellular Neuroscience · doi:10.3389/fncel.2019.00555 · Cited by 20 · see citing works
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Reyes‐Resina, I., Samer, S., Kreutz, M. R., & Oelschlegel, A. M. (2021) · Frontiers in Molecular Neuroscience · doi:10.3389/fnmol.2021.767384 · Cited by 19 · see citing works
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Maier, J. G., Kühn, M., Mainberger, F., Nachtsheim, K., Guo, S., Bucsenez, U., Feige, B., Mikutta, C. A., Spiegelhalder, K., Klöppel, S., et al. (2018) · SLEEP · doi:10.1093/sleep/zsy263 · Cited by 19 · see citing works
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Shuster, A. E., Morehouse, A. B., McDevitt, E. A., Chen, P., Whitehurst, L. N., Zhang, J., Sattari, N. S., Uzoigwe, T., Ekhlasi, A., Cai, D. J., et al. (2025) · SLEEP Advances · doi:10.1093/sleepadvances/zpaf004 · Cited by 18 · see citing works
Grønli, J., Clegern, W. C., Schmidt, M. A., Nemri, R. S., Rempe, M. J., Gallitano, A. L., & Wisor, J. P. (2016) · SLEEP · doi:10.5665/sleep.6324 · Cited by 17 · see citing works
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Li, M., Wang, X., Yao, X., Wang, X., Chen, F., Zhang, X., Sun, S., He, F., Jia, Q., Guo, M., et al. (2021) · Frontiers in Neuroscience · doi:10.3389/fnins.2021.645849 · Cited by 17 · see citing works
Raven, F., Vega-Medina, A., Schmidt, K., He, A., Vankampen, A. A., Balendran, V., & Aton, S. J. (2025) · SLEEP · doi:10.1093/sleep/zsaf064 · Cited by 11 · see citing works
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Aquino, G., Alfì, G., Riemann, D. W., Laurino, M., Menicucci, D., Piarulli, A., Palagini, L., & Gemignani, A. (2024) · Current Sleep Medicine Reports · doi:10.1007/s40675-024-00277-w · Cited by 11 · see citing works
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Eschenko, O. (2018) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-12-812028-6.00018-5 · Cited by 10 · see citing works
Martinez, J. D., Donnelly, M. J., Popke, D. S., Torres, D., Wilson, L. G., Brancaleone, W. P., Sheskey, S., Lin, C., Clawson, B. C., Jiang, S., et al. (2023) · Communications Biology · doi:10.1038/s42003-023-04798-y · Cited by 9 · see citing works
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Timofeev, I., & Chauvette, S. (2019) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-12-813743-7.00029-3 · Cited by 8 · see citing works
Aton, S. J., Seibt, J., & Frank, M. G. (2014) · Wiley eBooks · doi:10.1002/9780470015902.a0021395.pub2 · Cited by 8 · see citing works
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Alfonsa, H., Chakrabarty, A., Vyazovskiy, V. V., & Akerman, C. J. (2025) · Current Biology · doi:10.1016/j.cub.2025.01.050 · Cited by 7 · see citing works
The Ups and Downs of Synapses during Sleep and Learning
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Multiple Mechanistically Distinct Timescales of Neocortical Plasticity Occur During Habituation
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Lantz, C. L., & Quinlan, E. M. (2021) · Cerebral Cortex Communications · doi:10.1093/texcom/tgab016 · Cited by 5 · see citing works
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Klinzing, J. G., Nienborg, H., & Rauss, K. S. (2021) · Journal of Sleep Research · doi:10.1111/jsr.13335 · Cited by 5 · see citing works
Rapid prey capture learning slowly re-sets activity set points in rodent binocular visual cortexPreprint
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Leet, M. P., Chauhan, T., Cramer, T. L. M., Fong, M., & Bear, M. F. (2025) · Cell Reports · doi:10.1016/j.celrep.2025.116566 · Cited by 4 · see citing works
Kaneko, M., Hoseini, M. S., Waschek, J. A., & Stryker, M. P. (2024) · Journal of Neurophysiology · doi:10.1152/jn.00463.2023 · Cited by 4 · see citing works
Mofrad, M. H., Gilmore, G., Koller, D. P., Mirsattari, S. M., Burneo, J. G., Steven, D. A., KHAN, A. R., Marti, A. S., & Muller, L. (2022) · eLife · doi:10.7554/elife.75769 · Cited by 4 · see citing works
Vadakkan, K. I. (2016) · Sleep Science · doi:10.1016/j.slsci.2016.05.001 · Cited by 4 · see citing works
Frank, M. G. (2019) · Springer eBooks · doi:10.1007/978-981-13-2814-5_5 · Cited by 4 · see citing works
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Spruyt, K. (2024) · Psychiatric Clinics of North America · doi:10.1016/j.psc.2023.06.003 · Cited by 3 · see citing works
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Timofeev, I., Bonjean, M., & Bazhenov, M. (2020) · Springer eBooks · doi:10.1007/978-1-0716-0653-7_5 · Cited by 3 · see citing works
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Chandra, R., Farah, F., Muñoz-Lobato, F., Bokka, A., Benedetti, K. L., Brueggemann, C., Saifuddin, F. A., Miller, J. M., Li, J., Chang, E., et al. (2020) · bioRxiv (Cold Spring Harbor Laboratory) · doi:10.1101/2020.11.24.395228 · Cited by 3 · see citing works
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Jourde, H. R., Sita, K. Z., Eyqvelle, Z., Brooks, M., & Coffey, E. B. J. (2026) · npj Science of Learning · doi:10.1038/s41539-025-00383-6 · Cited by 2 · see citing works
Balendran, V., Liu, J., Wu, K., Dong, A., & Aton, S. J. (2026) · SLEEP · doi:10.1093/sleep/zsag047 · Cited by 2 · see citing works
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Miyamoto, H., Mazaki, E., Makino, Y., Fang, Q., Hamada, T., Handa, Y., & Hensch, T. K. (2025) · Frontiers in Neural Circuits · doi:10.3389/fncir.2025.1537305 · Cited by 2 · see citing works
Sousouri, G., & Huber, R. (2019) · Handbook of behavioral neuroscience · doi:10.1016/b978-0-12-813743-7.00028-1 · Cited by 2 · see citing works
Finnie, P. S. B., Komorowski, R. W., & Bear, M. F. (2021) · SSRN Electronic Journal · doi:10.2139/ssrn.3806070 · Cited by 2 · see citing works
Niraula, S., Hauser, W. L., Rouse, A. G., & Subramanian, J. (2023) · Scientific Reports · doi:10.1038/s41598-023-47957-1 · Cited by 1 · see citing works
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Self-citationSleep and experience-dependent visual plasticity in the adult cerebral cortex: an update
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Malci, A., Montgomery, D. P., Hosamane, N. S., Whittle, K., & Sidorov, M. S. (2025) · Journal of Neuroscience · doi:10.1523/jneurosci.0508-25.2025 · Cited by 1 · see citing works
Diurnal modulation of optogenetically evoked neural signals
Donen, Y., Ikoma, Y., & Matsui, K. (2025) · Neuroscience Research · doi:10.1016/j.neures.2025.104981 · Cited by 1 · see citing works
- Authors
- Aton, S. J., Suresh, A., Broussard, C., & Frank, M. G.
- Affiliations
- University of Michigan (US)
- University of Chicago (US)
- University of Pennsylvania (US)
- Corresponding author
- Aton, Sara J.
- Venue
- SLEEP
- Publisher
- Oxford University Press (OUP)
- Published
- 2014-07-01
- Volume
- 37
- Issue
- 7
- Pages
- 1163-1170
- ISSN
- 0161-8105 (ISSN-L)
- 1550-9109
- PMC
- PMC4098801
- OpenAlex
- W2048245455
- Cited by
- 122
- References
- 28
- Citations by year
- 2026: 3 · 2025: 12 · 2024: 9 · 2023: 6 · 2022: 8 · 2021: 16 · 2020: 13 · 2019: 13 · 2018: 10 · 2017: 11 · 2016: 6 · 2015: 8 · 2014: 7
- FWCI
- 5.95
- Type
- journal article
- Language
- en
- Open access
- bronze
- doi.org
- Locations
- SLEEP (publishedVersion)
- PubMed Central (publishedVersion)
- PubMed (publishedVersion)
- Funders
- Alfred P. Sloan Foundation
- National Institutes of Health
- National Heart, Lung, and Blood Institute (R01HL114161)
- National Eye Institute (R01EY019022, R00EY021503)
- National Center for Chronic Disease Prevention and Health Promotion (DP2MH104119)
- Topics
- Life Sciences › Neuroscience › Cognitive Neuroscience › Sleep and Wakefulness Research
- Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
- Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neuroscience and Neuropharmacology Research
- Keywords
- visual cortex, orientation preference, experience-dependent plasticity, sleep deprivation, thalamocortical oscillations, memory consolidation, adult mice
- MeSH terms
- Animals, Learning, Male, Neurons, Photic Stimulation, Sleep, Sleep Deprivation, Visual Cortex, Long-Term Potentiation, Mice
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