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Cited by 42Visual perception and processing mechanismsNeurobiology and Insect Physiology ResearchNeural dynamics and brain function

Visual and motor signatures of locomotion dynamically shape a population code for feature detection in Drosophila

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Turner, Maxwell H, Krieger, Avery, Pang, Michelle M, Clandinin, Thomas R·2022·eLife
DOI 10.7554/elife.82587PMC PMC9651947

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Abstract

Natural vision is dynamic: as an animal moves, its visual input changes dramatically. How can the visual system reliably extract local features from an input dominated by self-generated signals? In Drosophila , diverse local visual features are represented by a group of projection neurons with distinct tuning properties. Here, we describe a connectome-based volumetric imaging strategy to measure visually evoked neural activity across this population. We show that local visual features are jointly represented across the population, and a shared gain factor improves trial-to-trial coding fidelity. A subset of these neurons, tuned to small objects, is modulated by two independent signals associated with self-movement, a motor-related signal, and a visual motion signal associated with rotation of the animal. These two inputs adjust the sensitivity of these feature detectors across the locomotor cycle, selectively reducing their gain during saccades and restoring it during intersaccadic intervals. This work reveals a strategy for reliable feature detection during locomotion.

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  • Exact matches between model and real LC responses were unlikely owing to differences in behavioural state during courtship and during imaging.

    “exact matches were unlikely owing to differences in behavioural state during courtship (on which the 1-to-1 network was trained) and during imaging11,31.”

    From Mapping model units to visual neurons reveals population code for social behaviour (2024) · cites this paper as [31]

    The Results section, “Walking behavior selectively suppresses responses of small-object detecting glomeruli” (page unavailable), shows that walking weakens visual responses in some LC-associated glomeruli. This supports the premise that behavioural state can affect LC responses, but the paper does not compare courtship with imaging or establish that such a difference makes exact model–response matches unlikely. (LLM, conf=0.83)

    Experimental — accuracy not yet measured

  • Even simple stimuli can drive responses in multiple LC types.

    “As recordings from LC neurons reveal that even simple stimuli can drive responses in multiple LC types29–31”

    From Mapping model units to visual neurons reveals population code for social behaviour (2024) · cites this paper as [31]

  • Model LPLC2 was driven by large female sizes.

    “other model LC units, such as LPLC2, were driven by large female sizes, consistent with its known response to looming stimuli17,24,25,31.”

    From Mapping model units to visual neurons reveals population code for social behaviour (2024) · cites this paper as [31]

  • The model extends beyond findings from direct recordings of LC neurons, even in behaving flies.

    “We show that the model extends beyond findings from direct recordings of LC neurons29,30, even in behaving flies11,31.”

    From Mapping model units to visual neurons reveals population code for social behaviour (2024) · cites this paper as [31]

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Research works printed but not linked: 87

  1. Aimon S Katsuki T Jia T Grosenick L Broxton M Deisseroth K Sejnowski TJ Greenspan RJ 2019 Fast near-whole-brain imaging in adult Drosophila during responses to stimuli and behavior PLOS Biology 17 e2006732 10.1371/journal.pbio.2006732 30768592 PMC6395010 · DOI
  2. Ala-Laurila P Greschner M Chichilnisky EJ Rieke F 2011 Cone photoreceptor contributions to noise and correlations in the retinal output Nature Neuroscience 14 1309 1316 10.1038/nn.2927 21926983 PMC3183110 · DOI
  3. Angelaki DE Hess BJM 2005 Self-motion-induced eye movements: effects on visual acuity and navigation Nature Reviews. Neuroscience 6 966 976 10.1038/nrn1804 16340956 · DOI
  4. Aptekar JW Shoemaker PA Frye MA 2012 Figure tracking by flies is supported by parallel visual streams Current Biology 22 482 487 10.1016/j.cub.2012.01.044 22386313 · DOI
  5. Aptekar JW Keleş MF Lu PM Zolotova NM Frye MA 2015 Neurons forming optic glomeruli compute figure-ground discriminations in Drosophila The Journal of Neuroscience 35 7587 7599 10.1523/JNEUROSCI.0652-15.2015 25972183 PMC4429157 · DOI
  6. Averbeck BB Lee D 2006 Effects of noise correlations on information encoding and decoding Journal of Neurophysiology 95 3633 3644 10.1152/jn.00919.2005 16554512 · DOI
  7. Baccus SA Olveczky BP Manu M Meister M 2008 A retinal circuit that computes object motion The Journal of Neuroscience 28 6807 6817 10.1523/JNEUROSCI.4206-07.2008 18596156 PMC6670970 · DOI
  8. Bates AS Manton JD Jagannathan SR Costa M Schlegel P Rohlfing T Jefferis GS 2020 The natverse, a versatile toolbox for combining and analysing neuroanatomical data eLife 9 e53350 10.7554/eLife.53350 32286229 PMC7242028 · DOI · Paper page
  9. Binda P Morrone MC 2018 Vision during saccadic eye movements Annual Review of Vision Science 4 193 213 10.1146/annurev-vision-091517-034317 30222534 · DOI
  10. Bogovic JA Otsuna H Heinrich L Ito M Jeter J Meissner G Nern A Colonell J Malkesman O Ito K Saalfeld S 2020 An unbiased template of the Drosophila brain and ventral nerve cord PLOS ONE 15 e0236495 10.1371/journal.pone.0236495 33382698 PMC7774840 · DOI · Paper page
  11. Bolzon DM Nordström K O’Carroll DC 2009 Local and large-range inhibition in feature detection The Journal of Neuroscience 29 14143 14150 10.1523/JNEUROSCI.2857-09.2009 19906963 PMC6665075 · DOI
  12. Borst A Haag J Reiff DF 2010 Fly motion vision Annual Review of Neuroscience 33 49 70 10.1146/annurev-neuro-060909-153155 20225934 · DOI
  13. Bremmer F Kubischik M Hoffmann KP Krekelberg B 2009 Neural dynamics of saccadic suppression The Journal of Neuroscience 29 12374 12383 10.1523/JNEUROSCI.2908-09.2009 19812313 PMC2787621 · DOI
  14. Brezovec LE Berger AB Druckmann S Clandinin TR 2022 Mapping the Neural Dynamics of Locomotion across the Drosophila Brain bioRxiv 10.1101/2022.03.20.485047 38242122 · DOI
  15. Britten KH Shadlen MN Newsome WT Movshon JA 1992 The analysis of visual motion: a comparison of neuronal and psychophysical performance The Journal of Neuroscience 12 4745 4765 1464765 PMC6575768
  16. Britten KH 2008 Mechanisms of self-motion perception Annual Review of Neuroscience 31 389 410 10.1146/annurev.neuro.29.051605.112953 18558861 · DOI
  17. Chiappe ME Seelig JD Reiser MB Jayaraman V 2010 Walking modulates speed sensitivity in Drosophila motion vision Current Biology 20 1470 1475 10.1016/j.cub.2010.06.072 20655222 PMC4435946 · DOI
  18. Collett T 1971 Visual neurones for tracking moving targets Nature 232 127 130 10.1038/232127a0 4933247 · DOI
  19. Collett TS Land MF 1975a Visual control of flight behaviour in the hoverflysyritta pipiens L Journal of Comparative Physiology? A 99 1 66 10.1007/BF01464710 · DOI
  20. Collett TS Land MF 1975b Visual spatial memory in a hoverfly Journal of Comparative Physiology? A 100 59 84 10.1007/BF00623930 · DOI
  21. Cowley BR Calhoun AJ Rangarajan N Pillow JW Murthy M 2022 One-to-One Mapping between Deep Network Units and Real Neurons Uncovers a Visual Population Code for Social Behavior bioRxiv 10.1101/2022.07.18.500505 · DOI
  22. Cruz TL Pérez SM Chiappe ME 2021 Fast tuning of posture control by visual feedback underlies gaze stabilization in walking Drosophila Current Biology 31 4596 4607 10.1016/j.cub.2021.08.041 34499851 PMC8556163 · DOI
  23. Deng B Li Q Liu X Cao Y Li B Qian Y Xu R Mao R Zhou E Zhang W Huang J Rao Y 2019 Chemoconnectomics: mapping chemical transmission in Drosophila Neuron 101 876 893 10.1016/j.neuron.2019.01.045 30799021 · DOI · Paper page
  24. Fenk LM Kim AJ Maimon G 2021 Suppression of motion vision during course-changing, but not course-stabilizing, navigational turns Current Biology 31 4608 4619 10.1016/j.cub.2021.09.068 34644548 · DOI
  25. Fischbach KF Dittrich APM 1989 The optic lobe of Drosophila melanogaster. I. A golgi analysis of wild-type structure Cell and Tissue Research 258 BF00218858 10.1007/BF00218858 1735111 · DOI · Paper page
  26. Franke F Fiscella M Sevelev M Roska B Hierlemann A da Silveira RA 2016 Structures of neural correlation and how they favor coding Neuron 89 409 422 10.1016/j.neuron.2015.12.037 26796692 PMC5424879 · DOI
  27. Fry SN Sayaman R Dickinson MH 2003 The aerodynamics of free-flight maneuvers in Drosophila Science 300 495 498 10.1126/science.1081944 12702878 · DOI
  28. Fujiwara T Cruz TL Bohnslav JP Chiappe ME 2017 A faithful internal representation of walking movements in the Drosophila visual system Nature Neuroscience 20 72 81 10.1038/nn.4435 27798632 · DOI
  29. Fujiwara T Brotas M Chiappe ME 2022 Walking strides direct rapid and flexible recruitment of visual circuits for course control in Drosophila Neuron 110 2124 2138 10.1016/j.neuron.2022.04.008 35525243 PMC9275417 · DOI · Paper page
  30. Geurten BRH Jähde P Corthals K Göpfert MC 2014 Saccadic body turns in walking Drosophila Frontiers in Behavioral Neuroscience 8 365 10.3389/fnbeh.2014.00365 25386124 PMC4205811 · DOI
  31. Hardcastle BJ Krapp HG 2016 Evolution of biological image stabilization Current Biology 26 R1010 R1021 10.1016/j.cub.2016.08.059 27780044 · DOI
  32. Juusola M Dau A Song Z Solanki N Rien D Jaciuch D Dongre SA Blanchard F de Polavieja GG Hardie RC Takalo J 2017 Microsaccadic sampling of moving image information provides Drosophila hyperacute vision eLife 6 e26117 10.7554/eLife.26117 28870284 PMC5584993 · DOI
  33. Keleş MF Frye MA 2017 Object-detecting neurons in Drosophila Current Biology 27 680 687 10.1016/j.cub.2017.01.012 28190726 PMC5340600 · DOI · Paper page
  34. Keleş MF Hardcastle BJ Städele C Xiao Q Frye MA 2020 Inhibitory interactions and columnar inputs to an object motion detector in Drosophila Cell Reports 30 2115 2124 10.1016/j.celrep.2020.01.061 32075756 PMC7210872 · DOI · Paper page
  35. Kerschensteiner D 2022 Feature detection by retinal ganglion cells Annual Review of Vision Science 8 135 169 10.1146/annurev-vision-100419-112009 35385673 · DOI
  36. Kim AJ Fenk LM Lyu C Maimon G 2017 Quantitative predictions orchestrate visual signaling in Drosophila Cell 168 280 294 10.1016/j.cell.2016.12.005 28065412 PMC6320683 · DOI · Paper page
  37. Kimmerle B Egelhaaf M 2000 Performance of fly visual interneurons during object fixation The Journal of Neuroscience 20 6256 6266 10934276 PMC6772600
  38. Klapoetke NC Nern A Peek MY Rogers EM Breads P Rubin GM Reiser MB Card GM 2017 Ultra-selective looming detection from radial motion opponency Nature 551 237 241 10.1038/nature24626 29120418 PMC7457385 · DOI · Paper page
  39. Klapoetke NC Nern A Rogers EM Rubin GM Reiser MB Card GM 2022 A functionally ordered visual feature map in the Drosophila brain Neuron 110 1700 1711 10.1016/j.neuron.2022.02.013 35290791 · DOI · Paper page
  40. Kohn JR Portes JP Christenson MP Abbott LF Behnia R 2021 Flexible filtering by neural inputs supports motion computation across states and stimuli Current Biology 31 5249 5260 10.1016/j.cub.2021.09.061 34670114 PMC8725177 · DOI
  41. Land MF 1999 Motion and vision: why animals move their eyes Journal of Comparative Physiology. A, Sensory, Neural, and Behavioral Physiology 185 341 352 10.1007/s003590050393 10555268 · DOI
  42. Leong JCS Esch JJ Poole B Ganguli S Clandinin TR 2016 Direction selectivity in Drosophila emerges from preferred-direction enhancement and null-direction suppression The Journal of Neuroscience 36 8078 8092 10.1523/JNEUROSCI.1272-16.2016 27488629 PMC4971360 · DOI
  43. Lettvin JY Maturana HR McCulloch WS Pitts WH 1959 What the frog’s eye tells the frog’s brain Proceedings of the IRE 47 1940 1951 10.1109/JRPROC.1959.287207 · DOI · Paper page
  44. Li CH Lee CK 1993 Minimum cross entropy thresholding Pattern Recognition 26 617 625 10.1016/0031-3203(93)90115-D · DOI
  45. Maimon G Straw AD Dickinson MH 2010 Active flight increases the gain of visual motion processing in Drosophila Nature Neuroscience 13 393 399 10.1038/nn.2492 20154683 · DOI
  46. Maisak MS Haag J Ammer G Serbe E Meier M Leonhardt A Schilling T Bahl A Rubin GM Nern A Dickson BJ Reiff DF Hopp E Borst A 2013 A directional tuning map of Drosophila elementary motion detectors Nature 500 212 216 10.1038/nature12320 23925246 · DOI · Paper page
  47. Mann K Gallen CL Clandinin TR 2017 Whole-brain calcium imaging reveals an intrinsic functional network in Drosophila Current Biology 27 2389 2396 10.1016/j.cub.2017.06.076 28756955 PMC5967399 · DOI
  48. Martinez-Conde S Otero-Millan J Macknik SL 2013 The impact of microsaccades on vision: towards a unified theory of saccadic function Nature Reviews. Neuroscience 14 83 96 10.1038/nrn3405 23329159 · DOI
  49. McAdams CJ Maunsell JHR 1999 Effects of attention on orientation-tuning functions of single neurons in macaque cortical area V4 The Journal of Neuroscience 19 431 441 10.1523/JNEUROSCI.19-01-00431.1999 9870971 PMC6782389 · DOI
  50. McBride EG Lee SYJ Callaway EM 2019 Local and global influences of visual spatial selection and locomotion in mouse primary visual cortex Current Biology 29 1592 1605 10.1016/j.cub.2019.03.065 31056388 PMC6529288 · DOI
  51. Moore RJD Taylor GJ Paulk AC Pearson T van Swinderen B Srinivasan MV 2014 FicTrac: a visual method for tracking spherical motion and generating fictive animal paths Journal of Neuroscience Methods 225 106 119 10.1016/j.jneumeth.2014.01.010 24491637 · DOI
  52. Moreno-Bote R Beck J Kanitscheider I Pitkow X Latham P Pouget A 2014 Information-limiting correlations Nature Neuroscience 17 1410 1417 10.1038/nn.3807 25195105 PMC4486057 · DOI
  53. Nordström K Barnett PD O’Carroll DC 2006 Insect detection of small targets moving in visual clutter PLOS Biology 4 e54 10.1371/journal.pbio.0040054 16448249 PMC1360098 · DOI
  54. Nordström K O’Carroll DC 2006 Small object detection neurons in female hoverflies Proceedings. Biological Sciences 273 1211 1216 10.1098/rspb.2005.3424 16720393 PMC1560283 · DOI
  55. Nordström K O’Carroll DC 2009 Feature detection and the hypercomplex property in insects Trends in Neurosciences 32 383 391 10.1016/j.tins.2009.03.004 19541374 · DOI
  56. Nordström K 2012 Neural specializations for small target detection in insects Current Opinion in Neurobiology 22 272 278 10.1016/j.conb.2011.12.013 22244741 · DOI
  57. Olveczky BP Baccus SA Meister M 2003 Segregation of object and background motion in the retina Nature 423 401 408 10.1038/nature01652 12754524 · DOI
  58. Otsuna H Ito K 2006 Systematic analysis of the visual projection neurons of Drosophila melanogaster. I. lobula-specific pathways The Journal of Comparative Neurology 497 928 958 10.1002/cne.21015 16802334 · DOI · Paper page
  59. Pacheco DA Thiberge SY Pnevmatikakis E Murthy M 2021 Auditory activity is diverse and widespread throughout the central brain of Drosophila Nature Neuroscience 24 93 104 10.1038/s41593-020-00743-y 33230320 PMC7783861 · DOI · Paper page
  60. Panser K Tirian L Schulze F Villalba S Jefferis GS Bühler K Straw AD 2016 Automatic segmentation of Drosophila neural compartments using GAL4 Expression Data Reveals Novel Visual Pathways. Current Biology 26 1943 1954 10.1016/j.cub.2016.05.052 27426516 PMC4985560 · DOI
  61. Pasupathy A Connor CE 2001 Shape representation in area V4: position-specific tuning for boundary conformation Journal of Neurophysiology 86 2505 2519 10.1152/jn.2001.86.5.2505 11698538 · DOI · Paper page
  62. Pfeiffer BD Ngo TTB Hibbard KL Murphy C Jenett A Truman JW Rubin GM 2010 Refinement of tools for targeted gene expression in Drosophila Genetics 186 735 755 10.1534/genetics.110.119917 20697123 PMC2942869 · DOI · Paper page
  63. Piscopo DM El-Danaf RN Huberman AD Niell CM 2013 Diverse visual features encoded in mouse lateral geniculate nucleus The Journal of Neuroscience 33 4642 4656 10.1523/JNEUROSCI.5187-12.2013 23486939 PMC3665609 · DOI
  64. Pruszynski JA Zylberberg J 2019 The language of the brain: real-world neural population codes Current Opinion in Neurobiology 58 30 36 10.1016/j.conb.2019.06.005 31326721 · DOI
  65. Reynolds AM Frye MA 2007 Free-flight odor tracking in Drosophila is consistent with an optimal intermittent scale-free search PLOS ONE 2 e354 10.1371/journal.pone.0000354 17406678 PMC1831497 · DOI
  66. Ribeiro IMA Drews M Bahl A Machacek C Borst A Dickson BJ 2018 Visual projection neurons mediating directed courtship in Drosophila Cell 174 607 621 10.1016/j.cell.2018.06.020 30033367 · DOI · Paper page
  67. Romo R Hernández A Zainos A Salinas E 2003 Correlated neuronal discharges that increase coding efficiency during perceptual discrimination Neuron 38 649 657 10.1016/s0896-6273(03)00287-3 12765615 · DOI
  68. Rucci M Victor JD 2015 The unsteady eye: an information-processing stage, not a bug Trends in Neurosciences 38 195 206 10.1016/j.tins.2015.01.005 25698649 PMC4385455 · DOI
  69. Rumyantsev OI Lecoq JA Hernandez O Zhang Y Savall J Chrapkiewicz R Li J Zeng H Ganguli S Schnitzer MJ 2020 Fundamental bounds on the fidelity of sensory cortical coding Nature 580 100 105 10.1038/s41586-020-2130-2 32238928 · DOI
  70. Stringer C Michaelos M Tsyboulski D Lindo SE Pachitariu M 2021 High-Precision coding in visual cortex Cell 184 2767 2778 10.1016/j.cell.2021.03.042 33857423 · DOI
  71. Suver MP Mamiya A Dickinson MH 2012 Octopamine neurons mediate flight-induced modulation of visual processing in Drosophila Current Biology 22 2294 2302 10.1016/j.cub.2012.10.034 23142045 · DOI
  72. Tanaka R Clark DA 2020 Object-displacement-sensitive visual neurons drive freezing in Drosophila Current Biology 30 2532 2550 10.1016/j.cub.2020.04.068 32442466 PMC8716191 · DOI · Paper page
  73. Tanaka R Clark DA 2022 Neural mechanisms to exploit positional geometry for collision avoidance Current Biology 32 2357 2374 10.1016/j.cub.2022.04.023 35508172 PMC9177691 · DOI
  74. Turner MH Mann K Clandinin TR 2021 The connectome predicts resting-state functional connectivity across the Drosophila brain Current Biology 31 2386 2394 10.1016/j.cub.2021.03.004 33770490 PMC8519013 · DOI
  75. Tustison NJ Cook PA Holbrook AJ Johnson HJ Muschelli J Devenyi GA Duda JT Das SR Cullen NC Gillen DL Yassa MA Stone JR Gee JC Avants BB 2021 The antsx ecosystem for quantitative biological and medical imaging Scientific Reports 11 9068 10.1038/s41598-021-87564-6 33907199 PMC8079440 · DOI
  76. Van Der Linde I Rajashekar U Bovik AC Cormack LK 2009 Doves: a database of visual eye movements Spatial Vision 22 161 177 10.1163/156856809787465636 19228456 · DOI
  77. van Hateren JH van der Schaaf A 1998 Independent component filters of natural images compared with simple cells in primary visual cortex Proceedings of the Royal Society of London. Series B 265 359 366 10.1098/rspb.1998.0303 9523437 PMC1688904 · DOI · Paper page
  78. Walls GL 1962 The evolutionary history of eye movements Vision Research 2 69 80 10.1016/0042-6989(62)90064-0 · DOI
  79. Warzecha AK Egelhaaf M Borst A 1993 Neural circuit tuning fly visual interneurons to motion of small objects. I. dissection of the circuit by pharmacological and photoinactivation techniques Journal of Neurophysiology 69 329 339 10.1152/jn.1993.69.2.329 8459270 · DOI
  80. Wiederman SD Shoemaker PA O’Carroll DC 2008 A model for the detection of moving targets in visual clutter inspired by insect physiology PLOS ONE 3 e2784 10.1371/journal.pone.0002784 18665213 PMC2464731 · DOI
  81. Wiederman SD O’Carroll DC 2011 Discrimination of features in natural scenes by a dragonfly neuron The Journal of Neuroscience 31 7141 7144 10.1523/JNEUROSCI.0970-11.2011 21562276 PMC6703221 · DOI
  82. Wu M Nern A Williamson WR Morimoto MM Reiser MB Card GM Rubin GM 2016 Visual projection neurons in the Drosophila lobula link feature detection to distinct behavioral programs eLife 5 e21022 10.7554/eLife.21022 28029094 PMC5293491 · DOI · Paper page
  83. Wurtz RH 2018 Corollary discharge contributions to perceptual continuity across saccades Annual Review of Vision Science 4 215 237 10.1146/annurev-vision-102016-061207 30222532 · DOI
  84. York RA Brezovec LE Coughlan J Herbst S Krieger A Lee SY Pratt B Smart AD Song E Suvorov A Matute DR Tuthill JC Clandinin TR 2022 The evolutionary trajectory of drosophilid walking Current Biology 32 3005 3015 10.1016/j.cub.2022.05.039 35671756 PMC9329251 · DOI
  85. Zohary E Shadlen MN Newsome WT 1994 Correlated neuronal discharge rate and its implications for psychophysical performance Nature 370 140 143 10.1038/370140a0 8022482 · DOI · Paper page
  86. Zuber BL Stark L Cook G 1965 Microsaccades and the velocity-amplitude relationship for saccadic eye movements Science 150 1459 1460 10.1126/science.150.3702.1459 5855207 · DOI
  87. Zylberberg J Cafaro J Turner MH Shea-Brown E Rieke F 2016 Direction-selective circuits shape noise to ensure a precise population code Neuron 89 369 383 10.1016/j.neuron.2015.11.019 26796691 PMC4724064 · DOI

Cited by

Sorted by citations

Authors
Turner, M. H., Krieger, A., Pang, M. M., & Clandinin, T. R.
Affiliations
Stanford University (US)
Corresponding author
  • Turner, Maxwell H
  • Clandinin, Thomas R
ORCID
Venue
eLife
Publisher
eLife Sciences Publications, Ltd
Published
2022-10-27
Volume
11
ISSN
2050-084X (ISSN-L)
DOI
10.7554/elife.82587
PMC
PMC9651947
OpenAlex
W4307362263
Cited by
42
References
13
Citations by year
2026: 7 · 2025: 12 · 2024: 12 · 2023: 9 · 2022: 2
FWCI
4.51
Type
journal article
Language
en
Open access
Licence
Locations
  • eLife (publishedVersion, cc-by)
  • bioRxiv (Cold Spring Harbor Laboratory) (acceptedVersion, cc-by-nc-nd)
  • PubMed Central (publishedVersion, cc-by)
  • PubMed (publishedVersion)
  • DOAJ (DOAJ: Directory of Open Access Journals) (submittedVersion, cc-by-sa)
Funders
  • National Institutes of Health (F32-MH118707, K99-EY032549, R01-EY022638, R01NS110060)
  • National Science Foundation (GRFP)
  • National Defense Science and Engineering Graduate (Fellowship)
Topics
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Visual perception and processing mechanisms
  • Life Sciences › Neuroscience › Cellular and Molecular Neuroscience › Neurobiology and Insect Physiology Research
  • Life Sciences › Neuroscience › Cognitive Neuroscience › Neural dynamics and brain function
Keywords
Drosophila, feature detection, population coding, locomotion, self-motion, saccades, projection neurons, visual motion, motor signals, gain modulation, volumetric imaging, connectome
MeSH terms
Animals, Drosophila, Interneurons, Locomotion, Motion Perception, Neurons, Vision, Ocular

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