Snyder, Solomon H.

Amino Acid Signaling to MTOR Mediated by Inositol Polyphosphate Multikinase

Kim, S., Kim, S. F., Maag, D., Maxwell, M. J., Resnick, A. C., Juluri, K. R., Chakraborty, A., Koldobskiy, M. A., Cha, S. H., Barrow, R., et al. (2011) · Cell Metabolism

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 144

Inositol polyphosphate multikinase (ArgRIII) determines nuclear mRNA export in Saccharomyces cerevisiae

Saiardi, A., Caffrey, J. J., Snyder, S. H., & Shears, S. B. (2000) · FEBS Letters

Fungal and yeast genetics researchRNA Research and Splicing

Cited by 139

Nitric oxide S -nitrosylates serine racemase, mediating feedback inhibition of d -serine formation

Mustafa, A. K., Kumar, M., Selvakumar, B., Ho, G. P. H., Ehmsen, J. T., Barrow, R. K., Amzel, L. M., & Snyder, S. H. (2007) · Proceedings of the National Academy of Sciences

Amino Acid Enzymes and MetabolismNeuroscience and Neuropharmacology Research

Cited by 136

Rhes, a Striatal-selective Protein Implicated in Huntington Disease, Binds Beclin-1 and Activates Autophagy

Mealer, R. G., Murray, A. J., Shahani, N., Subramaniam, S., & Snyder, S. H. (2014) · Journal of Biological Chemistry

Genetic Neurodegenerative DiseasesAutophagy in Disease and Therapy

Cited by 124

Inositol Polyphosphate Multikinase Is a Physiologic PI3-Kinase That Activates Akt/PKB

Maag, D., Maxwell, M. J., Hardesty, D. A., Boucher, K. L., Choudhari, N., Hanno, A. G., Ma, J. F., Snowman, A. S., Pietropaoli, J. W., Xu, R., et al. (2011) · Proceedings of the National Academy of Sciences

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 122

Inositol Polyphosphate Multikinase Is a Nuclear PI3-Kinase with Transcriptional Regulatory Activity

Resnick, A. C., Snowman, A. M., Kang, B. N., Hurt, K. J., Snyder, S. H., & Saiardi, A. (2005) · Proceedings of the National Academy of Sciences

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 119

D-serine in glia and neurons derives from 3-phosphoglycerate dehydrogenase

Ehmsen, J. T., Ma, T. M., Sason, H., Rosenberg, D., Ogo, T., Furuya, S., Snyder, S. H., & Wolosker, H. (2013) · Journal of Neuroscience

Amino Acid Enzymes and MetabolismNeuroscience and Neuropharmacology Research

Cited by 118

Mammalian inositol polyphosphate multikinase synthesizes inositol 1,4,5-trisphosphate and an inositol pyrophosphate

Saiardi, A., Nagata, E., Luo, H. R., Sawa, A., Luo, X., Snowman, A. M., & Snyder, S. H. (2001) · Proceedings of the National Academy of Sciences

Protein Kinase Regulation and GTPase SignalingCalcium signaling and nucleotide metabolism

Cited by 110

S-nitrosylation of AMPA receptor GluA1 regulates phosphorylation, single-channel conductance, and endocytosis

Selvakumar, B., Jenkins, M. A., Hussain, N. K., Huganir, R. L., Traynelis, S. F., & Snyder, S. H. (2013) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchReceptor Mechanisms and Signaling

Cited by 97

Glutathione is a physiologic reservoir of neuronal glutamate

Koga, M., Serritella, A. V., Messmer, M. M., Hayashi-Takagi, A., Hester, L. D., Snyder, S. H., Sawa, A., & Sedlak, T. W. (2011) · Biochemical and Biophysical Research Communications

Sulfur Compounds in BiologyNeuroscience and Neuropharmacology Research

Cited by 73

Cocaine elicits autophagic cytotoxicity via a nitric oxide-GAPDH signaling cascade

Guha, P., Harraz, M. M., & Snyder, S. H. (2016) · Proceedings of the National Academy of Sciences

Autophagy in Disease and TherapyCell death mechanisms and regulation

Cited by 70

Inositol Polyphosphate Multikinase Is a Coactivator of P53-Mediated Transcription and Cell Death

Xu, R., Sen, N., Paul, B. D., Snowman, A. M., Rao, F., Vandiver, M. S., Xu, J., & Snyder, S. H. (2013) · Science Signaling

Cancer-related Molecular PathwaysPI3K/AKT/mTOR signaling in cancer

Cited by 52

Cetirizine: Actions on neurotransmitter receptors

Snowman, A. M., & Snyder, S. H. (1990) · Journal of Allergy and Clinical Immunology

Mast cells and histamineAllergic Rhinitis and Sensitization

Cited by 49

IPMK Mediates Activation of ULK Signaling and Transcriptional Regulation of Autophagy Linked to Liver Inflammation and Regeneration

Guha, P., Tyagi, R., Chowdhury, S., Reilly, L., Fu, C., Xu, R., Resnick, A. C., & Snyder, S. H. (2019) · Cell Reports

Autophagy in Disease and TherapyLiver physiology and pathology

Cited by 48

Inositol Polyphosphate Multikinase Is a Coactivator for Serum Response Factor-Dependent Induction of Immediate Early Genes

Kim, E., Tyagi, R., Lee, J.-Y., Park, J., Kim, Y.-R., Beon, J., Chen, P. Y., Cha, J. Y., Snyder, S. H., & Kim, S. (2013) · Proceedings of the National Academy of Sciences

Genomics and Chromatin DynamicsProtein Kinase Regulation and GTPase Signaling

Cited by 38

Histone H2AX deficiency causes neurobehavioral deficits and impaired redox homeostasis

Weyemi, U., Paul, B. D., Snowman, A. M., Jailwala, P., Nussenzweig, A., Bonner, W. M., & Snyder, S. H. (2018) · Nature Communications

Redox biology and oxidative stressDNA Repair Mechanisms

Cited by 37

Inositol Polyphosphate Multikinase Is a Transcriptional Coactivator Required for Immediate Early Gene Induction

Xu, R., Paul, B. D., Smith, D. R., Tyagi, R., Rao, F., Khan, A. B., Blech, D. J., Vandiver, M. S., Harraz, M. M., Guha, P., et al. (2013) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 36

Loss of PI3k Activity of Inositol Polyphosphate Multikinase Impairs PDK1-Mediated AKT Activation, Cell Migration, and Intestinal Homeostasis

Reilly, L., Semenza, E. R., Koshkaryan, G., Mishra, S., Chatterjee, S., Abramson, E., Mishra, P., Sei, Y., Wank, S. A., Donowitz, M., et al. (2023) · iScience

PI3K/AKT/mTOR signaling in cancerProtein Kinase Regulation and GTPase Signaling

Cited by 29

Inositol Polyphosphate Multikinase Inhibits Angiogenesis via Inositol Pentakisphosphate-Induced HIF-1α Degradation

Fu, C., Tyagi, R., Chin, A. C., Rojas, T., Li, R.-J., Guha, P., Bernstein, I. A., Rao, F., Xu, R., Cha, J. Y., et al. (2018) · Circulation Research

Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism

Cited by 28

Inositol hexakisphosphate kinase-2 non-catalytically regulates mitophagy by attenuating PINK1 signaling

Nagpal, L., Kornberg, M. D., & Snyder, S. H. (2022) · Proceedings of the National Academy of Sciences

Autophagy in Disease and TherapyParkinson's Disease Mechanisms and Treatments

Cited by 22

Noncatalytic Functions of IPMK Are Essential for Activation of Autophagy and Liver Regeneration

Guha, P., & Snyder, S. H. (2019) · Autophagy

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 18