Akhmanova, Anna

Tracking the ends: a dynamic protein network controls the fate of microtubule tips

Akhmanova, A., & Steinmetz, M. O. (2008) · Nature Reviews Molecular Cell Biology

Microtubule and mitosis dynamicsCellular Mechanics and Interactions

Cited by 1,047

Control of microtubule organization and dynamics: Two ends in the limelight

Akhmanova, A., & Steinmetz, M. O. (2015) · Nature Reviews Molecular Cell Biology

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

Cited by 895

Dynamic microtubules regulate dendritic spine morphology and synaptic plasticity

Jaworski, J., Kapitein, L. C., Gouveia, S. M., Dortland, B. R., Wulf, P. S., Grigoriev, I., Camera, P., Spangler, S. A., Di Stefano, P., Demmers, J., et al. (2009) · Neuron

Neuroscience and Neuropharmacology ResearchMicrotubule and mitosis dynamics

Cited by 643

An EB1-binding motif acts as a microtubule tip localization signal

Honnappa, S., Gouveia, S. M., Weisbrich, A., Damberger, F. F., Bhavesh, N. S., Jawhari, H., Grigoriev, I., van Rijssel, F. J. A., Buey, R. M., Lawera, A., et al. (2009) · Cell

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

Cited by 611

Vinculin associates with endothelial VE-cadherin junctions to control force-dependent remodeling

Huveneers, S., Oldenburg, J., Spanjaard, E., van der Krogt, G., Grigoriev, I., Akhmanova, A., Rehmann, H., & de Rooij, J. (2012) · Journal of Cell Biology

Cellular Mechanics and InteractionsCell Adhesion Molecules Research

Cited by 481

TRAK/Milton motor-adaptor proteins steer mitochondrial trafficking to axons and dendrites

van Spronsen, M., Mikhaylova, M., Lipka, J., Schlager, M. A., van den Heuvel, D. J., Kuijpers, M., Wulf, P. S., Keijzer, N., Demmers, J., Kapitein, L. C., et al. (2013) · Neuron

Microtubule and mitosis dynamicsMitochondrial Function and Pathology

Cited by 450

Bicaudal-D regulates COPI- independent Golgi-ER transport by recruiting the dynein-dynactin motor complex

Matanis, T., Akhmanova, A., Wulf, P., Del Nery, E., Weide, T., Stepanova, T., Galjart, N., Grosveld, F., Goud, B., De Zeeuw, C. I., et al. (2002) · Nature Cell Biology

Cellular transport and secretionMicrotubule and mitosis dynamics

Cited by 413

Mammalian end binding proteins control persistent microtubule growth

Komarova, Y., De Groot, C. O., Grigoriev, I., Gouveia, S. M., Munteanu, E. L., Schober, J. M., Honnappa, S., Buey, R. M., Hoogenraad, C. C., Dogterom, M., et al. (2009) · Journal of Cell Biology

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

Cited by 387

Rab6 regulates transport and targeting of exocytotic carriers

Grigoriev, I., Splinter, D., Keijzer, N., Wulf, P. S., Demmers, J., Ohtsuka, T., Modesti, M., Maly, I. V., Grosveld, F., Hoogenraad, C. C., et al. (2007) · Developmental Cell

Cellular transport and secretionExtracellular vesicles in disease

Cited by 361

Mechanisms of microtubule organization in differentiated animal cells

Akhmanova, A., & Kapitein, L. C. (2022) · Nature Reviews Molecular Cell Biology

Microtubule and mitosis dynamicsCellular Mechanics and Interactions

Cited by 233

TRIM46 Controls Neuronal Polarity and Axon Specification by Driving the Formation of Parallel Microtubule Arrays

van Beuningen, S. F. B., Will, L., Harterink, M., Chazeau, A., van Battum, E. Y., Frias, C. P., Franker, M. A. M., Katrukha, E. A., Stucchi, R., Vocking, K., et al. (2015) · Neuron

Axon Guidance and Neuronal SignalingNeurogenesis and neuroplasticity mechanisms

Cited by 225

A Proteome-wide Screen for Mammalian SxIP Motif-Containing Microtubule Plus-End Tracking Proteins

Jiang, K., Toedt, G., Montenegro Gouveia, S., Davey, N. E., Hua, S., van der Vaart, B., Grigoriev, I., Larsen, J., Pedersen, L. B., Bezstarosti, K., et al. (2012) · Current Biology

Microtubule and mitosis dynamicsGenetic and Kidney Cyst Diseases

Cited by 209

MAP2 defines a pre-axonal filtering Zone to regulate KIF1- versus KIF5-Dependent cargo transport in sensory neurons

Gumy, L. F., Katrukha, E. A., Grigoriev, I., Jaarsma, D., Kapitein, L. C., Akhmanova, A., & Hoogenraad, C. C. (2017) · Neuron

Microtubule and mitosis dynamicsCellular transport and secretion

Cited by 186

MAP7 family proteins regulate kinesin-1 recruitment and activation

Hooikaas, P. J., Martin, M., Mühlethaler, T., Kuijntjes, G.-J., Peeters, C. A. E., Katrukha, E. A., Ferrari, L., Stucchi, R., Verhagen, D. G. F., van Riel, W. E., et al. (2019) · Journal of Cell Biology

Microtubule and mitosis dynamicsGenetic and Kidney Cyst Diseases

Cited by 166

Pericentrosomal targeting of Rab6 secretory vesicles by Bicaudal-D-related protein 1 (BICDR-1) regulates neuritogenesis

Schlager, M. A., Kapitein, L. C., Grigoriev, I., Burzynski, G. M., Wulf, P. S., Keijzer, N., de Graaff, E., Fukuda, M., Shepherd, I. T., Akhmanova, A., et al. (2010) · The EMBO Journal

Cellular transport and secretionMicrotubule and mitosis dynamics

Cited by 165

A complex of Kif18b and MCAK promotes microtubule depolymerization and is negatively regulated by Aurora kinases

Tanenbaum, M. E., Macurek, L., van der Vaart, B., Galli, M., Akhmanova, A., & Medema, R. H. (2011) · Current Biology

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

Cited by 148

In vitro reconstitution of the functional interplay between MCAK and EB3 at microtubule plus ends

Montenegro Gouveia, S., Leslie, K., Kapitein, L. C., Buey, R. M., Grigoriev, I., Wagenbach, M., Smal, I., Meijering, E., Hoogenraad, C. C., Wordeman, L., et al. (2010) · Current Biology

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

Cited by 147

Dynamic behavior of GFP-CLIP-170 reveals fast protein turnover on microtubule plus ends

Dragestein, K. A., van Cappellen, W. A., van Haren, J., Tsibidis, G. D., Akhmanova, A., Knoch, T. A., Grosveld, F., & Galjart, N. (2008) · The Journal of Cell Biology

Microtubule and mitosis dynamicsCancer Treatment and Pharmacology

Cited by 116

Bicaudal d family adaptor proteins control the velocity of Dynein-based movements

Schlager, M. A., Serra-Marques, A., Grigoriev, I., Gumy, L. F., Esteves da Silva, M., Wulf, P. S., Akhmanova, A., & Hoogenraad, C. C. (2014) · Cell Reports

Microtubule and mitosis dynamicsCellular transport and secretion

Cited by 115

Concerted action of kinesins KIF5B and KIF13B promotes efficient secretory vesicle transport to microtubule plus ends

Serra-Marques, A., Martin, M., Katrukha, E. A., Grigoriev, I., Peeters, C. A., Liu, Q., Hooikaas, P. J., Yao, Y., Solianova, V., Smal, I., et al. (2020) · eLife

Microtubule and mitosis dynamicsCellular transport and secretion

Cited by 93

Developmental and activity-dependent miRNA expression profiling in primary hippocampal neuron cultures

van Spronsen, M., van Battum, E. Y., Kuijpers, M., Vangoor, V. R., Rietman, M. L., Pothof, J., Gumy, L. F., van IJcken, W. F. J., Akhmanova, A., Pasterkamp, R. J., et al. (2013) · PLoS ONE

MicroRNA in disease regulationNeurogenesis and neuroplasticity mechanisms

Cited by 82

Probing cytoskeletal modulation of passive and active intracellular dynamics using nanobody-functionalized quantum dots

Katrukha, E. A., Mikhaylova, M., van Brakel, H. X., van Bergen en Henegouwen, P. M., Akhmanova, A., Hoogenraad, C. C., & Kapitein, L. C. (2017) · Nature Communications

Microtubule and mitosis dynamicsQuantum Dots Synthesis And Properties

Cited by 80

KIF13B establishes a CAV1-enriched microdomain at the ciliary transition zone to promote Sonic hedgehog signalling

Schou, K. B., Mogensen, J. B., Morthorst, S. K., Nielsen, B. S., Aleliunaite, A., Serra-Marques, A., Fürstenberg, N., Saunier, S., Bizet, A. A., Veland, I. R., et al. (2017) · Nature Communications

Genetic and Kidney Cyst DiseasesHedgehog Signaling Pathway Studies

Cited by 72

Structural determinants of microtubule minus end preference in CAMSAP CKK domains

Atherton, J., Luo, Y., Xiang, S., Yang, C., Rai, A., Jiang, K., Stangier, M., Vemu, A., Cook, A. D., Wang, S., et al. (2019) · Nature Communications

Microtubule and mitosis dynamicsProtein Structure and Dynamics

Cited by 48