Bear, Mark F.

LTP and LTD

Malenka, R. C., & Bear, M. F. (2004) · Neuron

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 3,968

Learning induces long-term potentiation in the hippocampus

Whitlock, J. R., Heynen, A. J., Shuler, M. G., & Bear, M. F. (2006) · Science

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 1,913

Homosynaptic long-term depression in area CA1 of hippocampus and effects of N-methyl-D-aspartate receptor blockade.

Dudek, S. M., & Bear, M. F. (1992) · Proceedings of the National Academy of Sciences

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 1,708

The mGluR theory of fragile X mental retardation

Bear, M. F., Huber, K. M., & Warren, S. T. (2004) · Trends in Neurosciences

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 1,580

Synaptic plasticity: LTP and LTD

Bear, M. F., & Malenka, R. C. (1994) · Current Opinion in Neurobiology

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 1,355

Altered synaptic plasticity in a mouse model of fragile X mental retardation

Huber, K. M., Gallagher, S. M., Warren, S. T., & Bear, M. F. (2002) · Proceedings of the National Academy of Sciences

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 1,349

BDNF Regulates the Maturation of Inhibition and the Critical Period of Plasticity in Mouse Visual Cortex

Huang, Z. J., Kirkwood, A., Pizzorusso, T., Porciatti, V., Morales, B., Bear, M. F., Maffei, L., & Tonegawa, S. (1999) · Cell

Neuroscience and Neuropharmacology ResearchVisual perception and processing mechanisms

Cited by 1,198

Regulation of distinct AMPA receptor phosphorylation sites during bidirectional synaptic plasticity

Lee, H.-K., Barbarosie, M., Kameyama, K., Bear, M. F., & Huganir, R. L. (2000) · Nature

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 1,116

Correction of Fragile X Syndrome in Mice

Dölen, G., Osterweil, E., Rao, B. S. S., Smith, G. B., Auerbach, B. D., Chattarji, S., & Bear, M. F. (2007) · Neuron

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 979

Modulation of visual cortical plasticity by acetylcholine and noradrenaline

Bear, M. F., & Singer, W. (1986) · Nature

Neuroscience and Neuropharmacology ResearchVisual perception and processing mechanisms

Cited by 858

Synaptic Dysfunction in Neurodevelopmental Disorders Associated with Autism and Intellectual Disabilities

Zoghbi, H. Y., & Bear, M. F. (2012) · Cold Spring Harbor Perspectives in Biology

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 797

NMDA Induces Long-Term Synaptic Depression and Dephosphorylation of the GluR1 Subunit of AMPA Receptors in Hippocampus

Lee, H.-K., Kameyama, K., Huganir, R. L., & Bear, M. F. (1998) · Neuron

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 668

The Autistic Neuron: Troubled Translation?

Kelleher, R. J., & Bear, M. F. (2008) · Cell

Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research

Cited by 598

Mutations causing syndromic autism define an axis of synaptic pathophysiology

Auerbach, B. D., Osterweil, E. K., & Bear, M. F. (2011) · Nature

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 592

Ubiquitination Regulates PSD-95 Degradation and AMPA Receptor Surface Expression

Colledge, M., Snyder, E. M., Crozier, R. A., Soderling, J. A., Jin, Y., Langeberg, L. K., Lu, H., Bear, M. F., & Scott, J. D. (2003) · Neuron

Neuroscience and Neuropharmacology ResearchUbiquitin and proteasome pathways

Cited by 567

Forebrain-Specific Calcineurin Knockout Selectively Impairs Bidirectional Synaptic Plasticity and Working/Episodic-like Memory

Zeng, H., Chattarji, S., Barbarosie, M., Rondi-Reig, L., Philpot, B. D., Miyakawa, T., Bear, M. F., & Tonegawa, S. (2001) · Cell

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 498

Chronic Pharmacological mGlu5 Inhibition Corrects Fragile X in Adult Mice

Michalon, A., Sidorov, M., Ballard, T. M., Ozmen, L., Spooren, W., Wettstein, J. G., Jaeschke, G., Bear, M. F., & Lindemann, L. (2012) · Neuron

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 489

New views of Arc, a master regulator of synaptic plasticity

Shepherd, J. D., & Bear, M. F. (2011) · Nature Neuroscience

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 481

How Monocular Deprivation Shifts Ocular Dominance in Visual Cortex of Young Mice

Frenkel, M. Y., & Bear, M. F. (2004) · Neuron

Visual perception and processing mechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 412

The BCM theory of synapse modification at 30: interaction of theory with experiment

Cooper, L. N., & Bear, M. F. (2012) · Nature Reviews Neuroscience

Neuroscience and Neuropharmacology ResearchMemory and Neural Mechanisms

Cited by 395

Hypersensitivity to mGluR5 and ERK1/2 Leads to Excessive Protein Synthesis in the Hippocampus of a Mouse Model of Fragile X Syndrome

Osterweil, E. K., Krueger, D. D., Reinhold, K., & Bear, M. F. (2010) · The Journal of Neuroscience

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 384

The Pathophysiology of Fragile X (and What It Teaches Us about Synapses)

Bhakar, A. L., Dölen, G., & Bear, M. F. (2012) · Annual Review of Neuroscience

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 370

Smaller Dendritic Spines, Weaker Synaptic Transmission, but Enhanced Spatial Learning in Mice Lacking Shank1

Hung, A. Y., Futai, K., Sala, C., Valtschanoff, J. G., Ryu, J., Woodworth, M. A., Kidd, F. L., Sung, C. C., Miyakawa, T., Bear, M. F., et al. (2008) · The Journal of Neuroscience

Neuroscience and Neuropharmacology ResearchGenetics and Neurodevelopmental Disorders

Cited by 350

Drug development for neurodevelopmental disorders: lessons learned from fragile X syndrome

Berry-Kravis, E. M., Lindemann, L., Jønch, A. E., Apostol, G., Bear, M. F., Carpenter, R. L., Crawley, J. N., Curie, A., Des Portes, V., Hossain, F., et al. (2018) · Nature Reviews Drug Discovery

Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research

Cited by 336