Saper, Clifford B.

The hypothalamus

Saper, C. B., & Lowell, B. B. (2014) · Current Biology

Regulation of Appetite and ObesityHypothalamic control of reproductive hormones

Cited by 423

Midbrain, diencephalic and cortical relationships of the basal nucleus of meynert and associated structures in primates

Jones, E. G., Burton, H., Saper, C. B., & Swanson, L. W. (1976) · Journal of Comparative Neurology

Memory and Neural MechanismsNeuroscience and Neuropharmacology Research

Cited by 420

Chapter 1 The emotional motor system

Holstege, G., Bandler, R., & Saper, C. B. (1996) · Progress in Brain Research

Neural and Behavioral Psychology StudiesMemory and Neural Mechanisms

Cited by 379

EP3 prostaglandin receptors in the median preoptic nucleus are critical for fever responses

Lazarus, M., Yoshida, K., Coppari, R., Bass, C. E., Mochizuki, T., Lowell, B. B., & Saper, C. B. (2007) · Nature Neuroscience

Thermal Regulation in MedicinePain Mechanisms and Treatments

Cited by 367

Central autonomic system

Saper, C. B. (2004) · The Rat Nervous System

Heart Rate Variability and Autonomic ControlNeuroscience of respiration and sleep

Cited by 322

Concomitant loss of dynorphin, NARP, and orexin in narcolepsy

Crocker, A., España, R. A., Papadopoulou, M., Saper, C. B., Faraco, J., Sakurai, T., Honda, M., Mignot, E., & Scammell, T. E. (2005) · Neurology

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 301

Neural circuitry engaged by prostaglandins during the sickness syndrome

Saper, C. B., Romanovsky, A. A., & Scammell, T. E. (2012) · Nature Neuroscience

Thermal Regulation in MedicinePain Mechanisms and Treatments

Cited by 285

Galanin neurons in the ventrolateral preoptic area promote sleep and heat loss in mice

Kroeger, D., Absi, G., Gagliardi, C., Bandaru, S. S., Madara, J. C., Ferrari, L. L., Arrigoni, E., Münzberg, H., Scammell, T. E., Saper, C. B., et al. (2018) · Nature Communications

Sleep and Wakefulness ResearchCircadian rhythm and melatonin

Cited by 276

A Proposal for a Coordinated Effort for the Determination of Brainwide Neuroanatomical Connectivity in Model Organisms at a Mesoscopic Scale

Bohland, J. W., Wu, C., Barbas, H., Bokil, H., Bota, M., Breiter, H. C., Cline, H. T., Doyle, J. C., Freed, P. J., Greenspan, R. J., et al. (2009) · PLoS Computational Biology

Functional Brain Connectivity StudiesAdvanced Neuroimaging Techniques and Applications

Cited by 261

Role of endogenous sleep-wake and analgesic systems in anesthesia

Lu, J., Nelson, L. E., Franks, N., Maze, M., Chamberlin, N. L., & Saper, C. B. (2008) · Journal of Comparative Neurology

Sleep and Wakefulness ResearchAnesthesia and Sedative Agents

Cited by 230

Regional induction of tumor necrosis factor alpha expression in the mouse brain after systemic lipopolysaccharide administration.

Breder, C. D., Hazuka, C., Ghayur, T., Klug, C., Huginin, M., Yasuda, K., Teng, M., & Saper, C. B. (1994) · Proceedings of the National Academy of Sciences

Thermal Regulation in MedicineNeuroinflammation and Neurodegeneration Mechanisms

Cited by 226

Topographic organization of cardiovascular responses to electrical and glutamate microstimulation of the parabrachial nucleus in the rat

Chamberlin, N. L., & Saper, C. B. (1992) · Journal of Comparative Neurology

Heart Rate Variability and Autonomic ControlNeuroscience of respiration and sleep

Cited by 222

Recombinant adeno-associated virus vector: use for transgene expression and anterograde tract tracing in the CNS

Chamberlin, N. L., Du, B., de Lacalle, S., & Saper, C. B. (1998) · Brain Research

Virus-based gene therapy researchRNA Interference and Gene Delivery

Cited by 221

Suprachiasmatic neuron numbers and rest–activity circadian rhythms in older humans

Wang, J. L., Lim, A. S., Chiang, W., Hsieh, W., Lo, M., Schneider, J. A., Buchman, A. S., Bennett, D. A., Hu, K., & Saper, C. B. (2015) · Annals of Neurology

Circadian rhythm and melatoninSleep and Wakefulness Research

Cited by 217

Supramammillary glutamate neurons are a key node of the arousal system

Pedersen, N. P., Ferrari, L., Venner, A., Wang, J. L., Abbott, S. B. G., Vujovic, N., Arrigoni, E., Saper, C. B., & Fuller, P. M. (2017) · Nature Communications

Sleep and Wakefulness ResearchNeuroscience of respiration and sleep

Cited by 203

Staying awake for dinner: hypothalamic integration of sleep, feeding, and circadian rhythms

Saper, C. B. (2006) · Progress in Brain Research

Sleep and Wakefulness ResearchCircadian rhythm and melatonin

Cited by 178

Locus ceruleus and anterior cingulate cortex sustain wakefulness in a novel environment

Gompf, H. S., Mathai, C., Fuller, P. M., Wood, D. A., Pedersen, N. P., Saper, C. B., & Lu, J. (2010) · The Journal of Neuroscience

Sleep and Wakefulness ResearchNeurotransmitter Receptor Influence on Behavior

Cited by 176

Parallel preoptic pathways for thermoregulation

Yoshida, K., Li, X., Cano, G., Lazarus, M., & Saper, C. B. (2009) · The Journal of Neuroscience

Thermoregulation and physiological responsesNeuroscience of respiration and sleep

Cited by 160

A hypothalamic circuit for the circadian control of aggression

Todd, W. D., Fenselau, H., Wang, J. L., Zhang, R., Machado, N. L., Venner, A., Broadhurst, R. Y., Kaur, S., Lynagh, T., Olson, D. P., et al. (2018) · Nature Neuroscience

Circadian rhythm and melatoninNeurotransmitter Receptor Influence on Behavior

Cited by 154

Orexin neurons inhibit sleep to promote arousal

De Luca, R., Nardone, S., Grace, K. P., Venner, A., Cristofolini, M., Bandaru, S. S., Sohn, L. T., Kong, D., Mochizuki, T., Viberti, B., et al. (2022) · Nature Communications

Sleep and Wakefulness ResearchCircadian rhythm and melatonin

Cited by 130

CORRESPONDENCE OF MELANIN-PIGMENTED NEURONS IN HUMAN BRAIN WITH A1–A14 CATECHOLAMINE CELL ROUPS

SAPER, C. B., & PETITO, C. K. (1982) · Brain

Parkinson's Disease Mechanisms and TreatmentsNeuroscience and Neuropharmacology Research

Cited by 107

Reassessing the Role of Histaminergic Tuberomammillary Neurons in Arousal Control

Venner, A., Mochizuki, T., De Luca, R., Anaclet, C., Scammell, T. E., Saper, C. B., Arrigoni, E., & Fuller, P. M. (2019) · The Journal of Neuroscience

Sleep and Wakefulness ResearchCircadian rhythm and melatonin

Cited by 70

Pathological changes in frontal cortex from biopsy to autopsy in Alzheimer's disease

Bennett, D. A., Cochran, E. J., Saper, C. B., Leverenz, J. B., Gilley, D. W., & Wilson, R. S. (1993) · Neurobiology of Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 67

Metabolic Effects of Chronic Sleep Restriction in Rats

Vetrivelan, R., Fuller, P. M., Yokota, S., Lu, J., & Saper, C. B. (2012) · Sleep

Sleep and Wakefulness ResearchRegulation of Appetite and Obesity

Cited by 61