Osterrieder, Nikolaus

Virus-induced senescence is a driver and therapeutic target in COVID-19

Lee, S., Yu, Y., Trimpert, J., Benthani, F., Mairhofer, M., Richter-Pechanska, P., Wyler, E., Belenki, D., Kaltenbrunner, S., Pammer, M., et al. (2021) · Nature

Telomeres, Telomerase, and SenescenceCOVID-19 Clinical Research Studies

Cited by 350

A Therapeutic Non-self-reactive SARS-CoV-2 Antibody Protects from Lung Pathology in a COVID-19 Hamster Model

Kreye, J., Reincke, S. M., Kornau, H.-C., Sánchez-Sendin, E., Corman, V. M., Liu, H., Yuan, M., Wu, N. C., Zhu, X., Lee, C.-C. D., et al. (2020) · Cell

SARS-CoV-2 and COVID-19 ResearchMonoclonal and Polyclonal Antibodies Research

Cited by 347

A point mutation in a herpesvirus polymerase determines neuropathogenicity.

Goodman, L. B., Loregian, A., Perkins, G. A., Nugent, J., Buckles, E. L., Mercorelli, B., Kydd, J. H., Palù, G., Smith, K. C., Osterrieder, N., et al. (2007) · PLoS Pathogens

Herpesvirus Infections and TreatmentsAnimal Virus Infections Studies

Cited by 223

Codon Pair Bias Is a Direct Consequence of Dinucleotide Bias

Kunec, D., & Osterrieder, N. (2016) · Cell Reports

RNA and protein synthesis mechanismsEvolution and Genetic Dynamics

Cited by 159

Mechanism of Virus Attenuation by Codon Pair Deoptimization

Groenke, N., Trimpert, J., Merz, S., Conradie, A. M., Wyler, E., Zhang, H., Hazapis, O.-G., Rausch, S., Landthaler, M., Osterrieder, N., et al. (2020) · Cell Reports

RNA and protein synthesis mechanismsInfluenza Virus Research Studies

Cited by 85

Evaluation of immune responses following infection of ponies with an EHV-1 ORF1/2 deletion mutant.

Hussey, G. S., Hussey, S. B., Wagner, B., Horohov, D. W., Van de Walle, G. R., Osterrieder, N., Goehring, L. S., Rao, S., & Lunn, D. P. (2011) · Veterinary Research

Herpesvirus Infections and TreatmentsAnimal Virus Infections Studies

Cited by 73

Replication kinetics of neurovirulent versus non-neurovirulent equine herpesvirus type 1 strains in equine nasal mucosal explants.

Vandekerckhove, A. P., Glorieux, S., Gryspeerdt, A. C., Steukers, L., Duchateau, L., Osterrieder, N., Van de Walle, G. R., & Nauwynck, H. J. (2010) · Journal of General Virology

Herpesvirus Infections and TreatmentsAnimal Virus Infections Studies

Cited by 70

Experimental infection with equine herpesvirus type 1 (EHV-1) induces chorioretinal lesions.

Hussey, G., Goehring, L. S., Lunn, D. P., Hussey, S. B., Huang, T., Osterrieder, N., Powell, C., Hand, J., Holz, C., & Slater, J. (2013) · Veterinary Research

Herpesvirus Infections and TreatmentsAnimal Virus Infections Studies

Cited by 70

Herpesvirus chemokine-binding glycoprotein G (gG) efficiently inhibits neutrophil chemotaxis in vitro and in vivo.

Van de Walle, G. R., May, M. L., Sukhumavasi, W., von Einem, J., & Osterrieder, N. (2007) · The Journal of Immunology

Herpesvirus Infections and TreatmentsChemokine receptors and signaling

Cited by 55

Equine Herpesvirus 1 Entry via Endocytosis Is Facilitated by αV Integrins and an RSD Motif in Glycoprotein D

Van de Walle, G. R., Peters, S. T., VanderVen, B. C., O'Callaghan, D. J., & Osterrieder, N. (2008) · Journal of Virology

Herpesvirus Infections and TreatmentsAnimal Virus Infections Studies

Cited by 54

Glycoproteins D of equine herpesvirus type 1 (EHV-1) and EHV-4 determine cellular tropism independently of integrins

Azab, W., & Osterrieder, N. (2012) · Journal of Virology

Herpesvirus Infections and TreatmentsAnimal Virus Infections Studies

Cited by 49

Pathogenic potential of equine alphaherpesviruses: the importance of the mononuclear cell compartment in disease outcome

Osterrieder, N., & Van de Walle, G. R. (2010) · Veterinary Microbiology

Herpesvirus Infections and TreatmentsAnimal Virus Infections Studies

Cited by 46

Equine alphaherpesviruses (EHV-1 and EHV-4) differ in their efficiency to infect mononuclear cells during early steps of infection in nasal mucosal explants

Vandekerckhove, A. P., Glorieux, S., Gryspeerdt, A. C., Steukers, L., Van Doorsselaere, J., Osterrieder, N., Van de Walle, G. R., & Nauwynck, H. J. (2011) · Veterinary Microbiology

Herpesvirus Infections and TreatmentsAnimal Virus Infections Studies

Cited by 38

In vitro and in vivo characterization of equine herpesvirus type 1 (EHV-1) mutants devoid of the viral chemokine-binding glycoprotein G (gG).

von Einem, J., Smith, P. M., Van de Walle, G. R., O'Callaghan, D. J., & Osterrieder, N. (2007) · Virology

Herpesvirus Infections and TreatmentsAnimal Virus Infections Studies

Cited by 37

Equine herpesvirus 1 utilizes a novel herpesvirus entry receptor.

Frampton, A. R., Goins, W. F., Cohen, J. B., von Einem, J., Osterrieder, N., O'Callaghan, D. J., & Glorioso, J. C. (2005) · Journal of Virology

Herpesvirus Infections and TreatmentsAnimal Virus Infections Studies

Cited by 36

Viral genes and cellular markers associated with neurological complications during herpesvirus infections

Holz, C. L., Nelli, R. K., Wilson, M. E., Zarski, L. M., Azab, W., Baumgardner, R., Osterrieder, N., Pease, A., Zhang, L., Hession, S., et al. (2017) · Journal of General Virology

Herpesvirus Infections and TreatmentsAnimal Virus Infections Studies

Cited by 34

Equine herpesvirus type 1 pUL56 modulates innate responses of airway epithelial cells.

Soboll Hussey, G., Ashton, L. V., Quintana, A. M., Van de Walle, G. R., Osterrieder, N., & Lunn, D. P. (2014) · Virology

Herpesvirus Infections and Treatmentsinterferon and immune responses

Cited by 28

Role of gB and pUS3 in Equine Herpesvirus 1 Transfer between Peripheral Blood Mononuclear Cells and Endothelial Cells: a Dynamic In Vitro Model

Spiesschaert, B., Goldenbogen, B., Taferner, S., Schade, M., Mahmoud, M., Klipp, E., Osterrieder, N., & Azab, W. (2015) · Journal of Virology

Herpesvirus Infections and TreatmentsAnimal Virus Infections Studies

Cited by 24

Major histocompatibility complex class I downregulation induced by equine herpesvirus type 1 pUL56 is through dynamin-dependent endocytosis.

Huang, T., Lehmann, M. J., Said, A., Ma, G., & Osterrieder, N. (2014) · Journal of Virology

Herpesvirus Infections and TreatmentsCellular transport and secretion

Cited by 24

Equine herpesvirus type 1 infection induces procoagulant activity in equine monocytes.

Yeo, W. M., Osterrieder, N., & Stokol, T. (2013) · Veterinary Research

Blood Coagulation and Thrombosis MechanismsHerpesvirus Infections and Treatments

Cited by 22

Equine Herpesvirus type 1 modulates cytokine and chemokine profiles of mononuclear cells for efficient dissemination to target organs.

Pavulraj, S., Kamel, M., Stephanowitz, H., Liu, F., Plendl, J., Osterrieder, N., & Azab, W. (2020) · Viruses

Herpesvirus Infections and TreatmentsAnimal Virus Infections Studies

Cited by 13