Overexpression of dopamine D2 receptors reduces alcohol self‐administration

The Rat Brain in Stereotaxic Coordinates

Paxinos, G., & Watson, C. (1983) · Elsevier eBooks · doi:10.1016/c2009-0-63235-9 · Cited by 28,585 · see citing works

Unresponsiveness to Cannabinoids and Reduced Addictive Effects of Opiates in CB 1 Receptor Knockout Mice

Ledent, C. A., Valverde, O., Cossu, G., Petitet, F., Aubert, J.-F., Beslot, F., Böhme, G. A., Impérato, A., Pedrazzini, T., Roques, B. P., et al. (1999) · Science · doi:10.1126/science.283.5400.401 · Cited by 3,612 · see citing works

A psychomotor stimulant theory of addiction.

Wise, R. A., & Bozarth, M. A. (1987) · Psychological Review · doi:10.1037/0033-295x.94.4.469 · Cited by 2,747 · see citing works

Neurogenetic Adaptive Mechanisms in Alcoholism

Cloninger, C. R. (1987) · Science · doi:10.1126/science.2882604 · Cited by 2,203 · see citing works

Effects of nicotine on the nucleus accumbens and similarity to those of addictive drugs.

Pontieri, F. E., Tanda, G., Orzi, F., & Chiara, G. D. (1996) · Nature · doi:10.1038/382255a0 · Cited by 1,073 · see citing works

Allelic Association of Human Dopamine D2 Receptor Gene in Alcoholism

Blum, K. (1990) · JAMA: The Journal of the American Medical Association · doi:10.1001/jama.1990.03440150063027 · Cited by 1,055 · see citing works

The familial incidence of alcoholism: a review.

Cotton, N. S. (1979) · Journal of Studies on Alcohol · doi:10.15288/jsa.1979.40.89 · Cited by 796 · see citing works

Oral alcohol self-administration stimulates dopamine release in the rat nucleus accumbens: genetic and motivational determinants.

Weiss, F., Lorang, M. T., Bloom, F. E., & Koob, G. F. (1993) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)39420-6 · Cited by 751 · see citing works

Initiation of Ethanol Reinforcement using a Sucrose‐Substitution Procedure in Food‐ and Water‐Sated Rats

Samson, H. H. (1986) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1986.tb05120.x · Cited by 670 · see citing works

Allelic Association of the D2 Dopamine Receptor Gene With Receptor-Binding Characteristics in Alcoholism or Gene ism

Noble, E. P. (1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810310066012 · Cited by 655 · see citing works

Decreases in dopamine receptors but not in dopamine transporters in alcoholics

Volkow, N. D., Wang, G., Fowler, J. S., Logan, J., Hitzemann, R., Ding, Y., Pappas, N., Shea, C., & Piscani, K. (1996) · Alcoholism: Clinical and Experimental Research · doi:10.1111/j.1530-0277.1996.tb05936.x · Cited by 612 · see citing works

Reward Deficiency Syndrome

Blum, K. (2017) · Sage eBooks · doi:10.4135/9781483365817.n1156 · Cited by 474 · see citing works

Alcoholism and Heredity

Goodwin, D. W. (1979) · Archives of General Psychiatry · doi:10.1001/archpsyc.1979.01780010063006 · Cited by 323 · see citing works

Brain reward systems and abuse

Holman, B. (1988) · Neurochemistry International · doi:10.1016/0197-0186(88)90042-3 · Cited by 276 · see citing works

A Simultaneous Evaluation of Multiple Markers of Ethanol/Placebo Challenges in Sons of Alcoholics and Controls

Schuckit, M. A. (1988) · Archives of General Psychiatry · doi:10.1001/archpsyc.1988.01800270019002 · Cited by 275 · see citing works

Pharmacogenetics of responses to alcohol and genes that influence alcohol drinking.

Li, T. (2000) · Journal of Studies on Alcohol · doi:10.15288/jsa.2000.61.5 · Cited by 273 · see citing works

Alcohol preference and sensitivity are markedly reduced in mice lacking dopamine D2 receptors

Phillips, T. J., Brown, K. J., Burkhart‐Kasch, S., Wenger, C. D., Kelly, M. A., Rubinstein, M., Grandy, D. K., & Low, M. J. (1998) · Nature Neuroscience · doi:10.1038/2843 · Cited by 272 · see citing works

PET evaluation of the dopamine system of the human brain.

Volkow, N. D., Fowler, J., Sj, G., Logan, J., Wang, G., Ding, Y., & Dewey, S. L. (1996) · PubMed · Cited by 249 · see citing works

Alcoholism and Alleles of the Human D2 Dopamine Receptor Locus

Parsian, A. (1991) · Archives of General Psychiatry · doi:10.1001/archpsyc.1991.01810310073013 · Cited by 248 · see citing works

Parallel changes in dopamine D2 receptor binding in limbic forebrain associated with chronic mild stress-induced anhedonia and its reversal by imipramine

Papp, M., Klimek, V., & Willner, P. (1994) · Psychopharmacology · doi:10.1007/bf02245566 · Cited by 202 · see citing works

Densities of dopamine D2 receptors are reduced in CNS regions of alcohol-preferring P rats

McBride, W. J., Chernet, E., Dyr, W., Lumeng, L., & Li, T.-K. (1993) · Alcohol · doi:10.1016/0741-8329(93)90025-j · Cited by 160 · see citing works

D2 dopamine receptor Gene TaqI A1 and B1 restriction fragment length polymorphisms: Enhanced frequencies in psychostimulant-preferring polysubstance abusers

Persico, A. M., Bird, G. W. G., Gabbay, F. H., & Uhl, G. R. (1996) · Biological Psychiatry · doi:10.1016/0006-3223(95)00483-1 · Cited by 149 · see citing works

Ethanol as a neurochemical surrogate of conventional reinforcers: The dopamine-opioid link

Chiara, G. D., Acquas, E., & Tanda, G. (1996) · Alcohol · doi:10.1016/0741-8329(95)02034-9 · Cited by 120 · see citing works

Gene Therapy for Neurologic Disease

Suhr, S. T., & Gage, F. H. (1993) · Archives of Neurology · doi:10.1001/archneur.1993.00540110122012 · Cited by 109 · see citing works

RAPID COMMUNICATION: ALCOHOL-PREFERRING RATS HAVE FEWER DOPAMINE D2 RECEPTORS IN THE LIMBIC SYSTEM

Stefanini, E., FRAU, M., GARAU, M. G., GARAU, B., Fadda, F., & GESSA, G. L. (1992) · Alcohol and Alcoholism · doi:10.1093/oxfordjournals.alcalc.a045210 · Cited by 105 · see citing works

Low endogenous dopamine function in brain predisposes to high alcohol preference and consumption: reversal by increasing synaptic dopamine.

George, S. R., Fan, T., Ng, G., Jung, S., O’Dowd, B. F., & Naranjo, C. A. (1995) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)09574-6 · Cited by 103 · see citing works

Mesolimbic dopamine system in alcohol-preferring rats

Zhou, F. C., Zhang, J. K., Lumeng, L., & Li, T. (1995) · Alcohol · doi:10.1016/0741-8329(95)00010-o · Cited by 102 · see citing works

CNS mechanisms of alcohol self-administration.

McBride, W. J., Murphy, J. M., Gj, G., Ad, L., Yoshimoto, K., Lumeng, L., & Li, T. (1993) · PubMed · Cited by 97 · see citing works

Dopamine transporter and D 2 -receptor density in late-onset alcoholism

Repo, E., Kuikka, J. T., Bergström, K. A., Karhu, J., Hiltunen, J., Tiihonen, J., & Kuikka, J. T. (1999) · Psychopharmacology · doi:10.1007/s002130051173 · Cited by 96 · see citing works

Striatal Dopaminergic D2 Receptor Density Measured by [123I]Iodobenzamide SPECT in the Prediction of Treatment Outcome of Alcohol-Dependent Patients

Guardia, J., Catafau, A. M., Batlle, F., Mart쬼, J. C., Segura, L., Gonzalvo, B., Prat, G., Carriñº®³, I., & Casas, M. (2000) · American Journal of Psychiatry · doi:10.1176/ajp.157.1.127 · Cited by 94 · see citing works

Genotypic differences in brain dopamine receptor function in the DBA/2J and C57BL/6J inbred mouse strains

Ng, G., O’Dowd, B. F., & George, S. R. (1994) · European Journal of Pharmacology Molecular Pharmacology · doi:10.1016/0922-4106(94)90043-4 · Cited by 81 · see citing works

Ethanol preference following the sucrose-fading initiation procedure

Tolliver, G. A., Sadeghi, K. G., & Samson, H. H. (1988) · Alcohol · doi:10.1016/0741-8329(88)90036-5 · Cited by 80 · see citing works

Ethanol Reinforcement in the Alcohol Nonpreferring Rat: Initiation using Behavioral Techniques without Food Restriction

Samson, H. H., Tolliver, G. A., Lumeng, L., & Tk, L. (1989) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1989.tb00339.x · Cited by 75 · see citing works

Dopamine receptor agonist reduces ethanol self-administration in the ethanol-preferring C57BL/6J inbred mouse

Ng, G., & George, S. R. (1994) · European Journal of Pharmacology Molecular Pharmacology · doi:10.1016/0922-4106(94)90044-2 · Cited by 75 · see citing works

Serotonin and dopamine systems regulating alcohol intake.

McBride, W. J., Murphy, J. M., Gatto, G. J., Levy, A. D., Lumeng, L., & Li, T. (1991) · PubMed · Cited by 74 · see citing works

Microinjection of sulpiride into the nucleus accumbens increases ethanol drinking in alcohol-preferring (P) rats.

Ad, L., Murphy, J. M., McBride, W. J., Lumeng, L., & Li, T. (1991) · PubMed · Cited by 71 · see citing works

Drug Motivation and Abuse: A Neurobiological Perspective

Chiara, G. D., Acquas, E., & Carboni, E. (1992) · Annals of the New York Academy of Sciences · doi:10.1111/j.1749-6632.1992.tb25969.x · Cited by 70 · see citing works

On the relationship between D2 receptor density and neuroleptic-induced catalepsy among eight inbred strains of mice.

Kanes, S., Hitzemann, B. A., & Hitzemann, R. (1993) · Journal of Pharmacology and Experimental Therapeutics · doi:10.1016/s0022-3565(25)39355-9 · Cited by 63 · see citing works

Gene therapy strategies for pulmonary disease

Crystal, R. G. (1992) · The American Journal of Medicine · doi:10.1016/0002-9343(92)90607-d · Cited by 62 · see citing works

Involvement of Dopamine D2 Autoreceptors in the Ventral Tegmental Area on Alcohol and Saccharin Intake of the Alcohol-Preferring P Rat

Nowak, K., McBride, W. J., Lumeng, L., Li, T., & Murphy, J. M. (2000) · Alcoholism Clinical and Experimental Research · doi:10.1097/00000374-200004000-00021 · Cited by 56 · see citing works

Apomorphine and 7-OH DPAT reduce ethanol intake of P and HAD rats

Russell, R., McBride, W. J., Lumeng, L., Li, T., & Murphy, J. M. (1996) · Alcohol · doi:10.1016/0741-8329(95)00062-3 · Cited by 47 · see citing works

Patterns of Ethanol Consumption in a Continuous Access Situation: The Effect of Adding a Sweetener to the Ethanol Solution

Samson, H. H., Files, F. J., & Brice, G. T. (1996) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1996.tb01052.x · Cited by 46 · see citing works

Mμ and D2 Receptor Antisense Oligonucleotides Injected in Nucleus Accumbens Suppress High Alcohol Intake in Genetic Drinking HEP Rats

Myers, R. D., & Robinson, D. E. (1999) · Alcohol · doi:10.1016/s0741-8329(99)00015-4 · Cited by 43 · see citing works

Effects of Chronic Alcohol Consumption and Aging on Dopamine D1 Receptors in Fischer 344 Rats

Woods, J. M., Ricken, J. D., & Druse, M. J. (1995) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1995.tb01621.x · Cited by 42 · see citing works

A Genetic Linkage Study of the D2Dopamine Receptor Locus in Heavy Drinking and Alcoholism

Cook, C. C. H., Palsson, G., Turner, A., Holmes, D. S., Brett, P., Curtis, D., Pétursson, H., & Gurling, H. (1996) · The British Journal of Psychiatry · doi:10.1192/bjp.169.2.243 · Cited by 40 · see citing works

In vivo imaging of adenovirus-mediated over-expression of dopamine D2 receptors in rat striatum by positron emission tomography

Ogawa, O., Umegaki, H., Ishiwata, K., Asai, Y., Ikari, H., Oda, K., Toyama, H., Ingram, D. K., Roth, G. S., Iguchi, A., et al. (2000) · Neuroreport · doi:10.1097/00001756-200003200-00018 · Cited by 37 · see citing works

Effects of Chronic Alcohol Consumption and Aging on Dopamine D2 Receptors in Fischer 344 Rats

Tajuddin, N. F., & Druse, M. J. (1996) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1996.tb01057.x · Cited by 34 · see citing works

Adenovirus-mediated gene transfer of dopamine D2 receptor cDNA into rat striatum

Ikari, H., Liang, Z., Chernak, J. M., Mastrangeli, A., Kato, S., Kuo, H., Crystal, R. G., Ingram, D. K., & Roth, G. S. (1995) · Molecular Brain Research · doi:10.1016/0169-328x(95)00185-u · Cited by 31 · see citing works

Genetics and the Organization of the Basal Ganglia

HITZEMANN, R. J., Qian, Y., Kanes, S., Dains, K. M., & Hitzemann, B. A. (1995) · International review of neurobiology · doi:10.1016/s0074-7742(08)60524-3 · Cited by 22 · see citing works

Rotational behavior produced by adenovirusmediated gene transfer of dopamine D2 receptor into rat striatum

Umegaki, H., Chernak, J. M., Ikari, H., Roth, G. S., & Ingram, D. K. (1997) · Neuroreport · doi:10.1097/00001756-199711100-00027 · Cited by 22 · see citing works

ALCOHOLICS WITH THE DOPAMINE RECEPTOR DRD2 A1 ALLELE HAVE LOWER PLATELET MONOAMINE OXIDASE-B ACTIVITY THAN THOSE WITH THE A2 ALLELE: A PRELIMINARY STUDY

Eriksson, M. (2000) · Alcohol and Alcoholism · doi:10.1093/alcalc/35.5.493 · Cited by 22 · see citing works

On the selection of mice for haloperidol response and non-response

HITZEMANN, R. J., Dains, K. M., Bier‐Laning, C. M., & Zahniser, N. R. (1991) · Psychopharmacology · doi:10.1007/bf02244211 · Cited by 19 · see citing works

Application of gene therapy to treat age-related loss of dopamine D2 receptor

Ingram, D. K., Ikari, H., Umegaki, H., Chernak, J. M., & Roth, G. S. (1998) · Experimental Gerontology · doi:10.1016/s0531-5565(98)00043-6 · Cited by 18 · see citing works

In Vivo Links Between Neurochemistry and Behavioral Effects of Ethanol

Gonzales, R. A., & Kiianmaa, K. (1996) · Alcoholism Clinical and Experimental Research · doi:10.1111/j.1530-0277.1996.tb01777.x · Cited by 13 · see citing works

Ethanol-induced, nonexocytotic [3H]dopamine release from rat nucleus accumbens slices

Yan, Q. (2002) · Alcohol · doi:10.1016/s0741-8329(02)00217-3 · Cited by 12 · see citing works

Gene Therapy to Treat Parkinson's Disease.

Ikari, H., Umegaki, H., & Iguchi, A. (1999) · Nippon Ronen Igakkai Zasshi Japanese Journal of Geriatrics · doi:10.3143/geriatrics.36.103 · Cited by 5 · see citing works

Drug Addiction and Its Underlying Neurobiological Basis: Neuroimaging Evidence for the Involvement of the Frontal Cortex

Goldstein, R. Z., & Volkow, N. D. (2002) · American Journal of Psychiatry · doi:10.1176/appi.ajp.159.10.1642 · Cited by 2,667 · see citing works

The brain on drugs: from reward to addiction

Volkow, N. D., & Morales, M. (2015) · Cell · doi:10.1016/j.cell.2015.07.046 · Cited by 1,306 · see citing works

Dopamine in drug abuse and addiction: results from imaging studies and treatment implications

Volkow, N. D., Fowler, J. S., Wang, G.-J., & Swanson, J. M. (2004) · Molecular Psychiatry · doi:10.1038/sj.mp.4001507 · Cited by 1,101 · see citing works

Imaging dopamine's role in drug abuse and addiction

Volkow, N. D., Fowler, J. S., Wang, G. J., Baler, R., & Telang, F. (2009) · Neuropharmacology · doi:10.1016/j.neuropharm.2008.05.022 · Cited by 988 · see citing works

The addicted human brain: insights from imaging studies

Volkow, N. D., Fowler, J. S., & Wang, G.-J. (2003) · Journal of Clinical Investigation · doi:10.1172/jci18533 · Cited by 916 · see citing works

The Neuroscience of Drug Reward and Addiction

Volkow, N. D., Michaelides, M., & Baler, R. (2019) · Physiological Reviews · doi:10.1152/physrev.00014.2018 · Cited by 863 · see citing works

Overlapping neuronal circuits in addiction and obesity: evidence of systems pathology

Volkow, N. D., Wang, G.-J., Fowler, J. S., & Telang, F. (2008) · Philosophical Transactions of the Royal Society B: Biological Sciences · doi:10.1098/rstb.2008.0107 · Cited by 809 · see citing works

Obesity and addiction: Neurobiological overlaps

Volkow, N. D., Wang, G. ‐., Tomasi, D., & Baler, R. D. (2013) · Obesity Reviews · doi:10.1111/j.1467-789x.2012.01031.x · Cited by 800 · see citing works

The mesolimbic dopamine system: The final common pathway for the reinforcing effect of drugs of abuse?

Pierce, R. C., & Kumaresan, V. (2006) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2005.04.016 · Cited by 913 · see citing works

Drug addiction: the neurobiology of behaviour gone awry

Volkow, N. D., & Li, T. (2004) · Nature reviews. Neuroscience · doi:10.1038/nrn1539 · Cited by 620 · see citing works

The addicted human brain viewed in the light of imaging studies: brain circuits and treatment strategies

Volkow, N. D., Fowler, J. S., & Wang, G.-J. (2004) · Neuropharmacology · doi:10.1016/j.neuropharm.2004.07.019 · Cited by 616 · see citing works

Dopamine in Drug Abuse and Addiction: Results of Imaging Studies and Treatment Implications

Volkow, N. D., Fowler, J. S., Wang, G.-J., Swanson, J. M., & Telang, F. (2007) · Archives of Neurology · doi:10.1001/archneur.64.11.1575 · Cited by 605 · see citing works

Addiction circuitry in the human brain

Volkow, N. D., Wang, G.-J., Fowler, J. S., & Tomasi, D. (2012) · Annual Review of Pharmacology and Toxicology · doi:10.1146/annurev-pharmtox-010611-134625 · Cited by 592 · see citing works

Neurobiologic processes in drug reward and addiction

Adinoff, B. (2004) · Harvard Review of Psychiatry · doi:10.1080/10673220490910844 · Cited by 546 · see citing works

Dopamine Signaling in reward-related behaviors

Baik, J. (2013) · Frontiers in Neural Circuits · doi:10.3389/fncir.2013.00152 · Cited by 534 · see citing works

Role of dopamine, the frontal cortex and memory circuits in drug addiction: insight from imaging studies

Volkow, N. (2002) · Neurobiology of Learning and Memory · doi:10.1006/nlme.2002.4099 · Cited by 514 · see citing works

D2 dopamine receptor gene in psychiatric and neurologic disorders and its phenotypes

Noble, E. P. (2003) · American Journal of Medical Genetics Part B: Neuropsychiatric Genetics · doi:10.1002/ajmg.b.10005 · Cited by 501 · see citing works

Similarity Between Obesity and Drug Addiction as Assessed by Neurofunctional Imaging: A Concept Review

Wang, G.-J., Volkow, N. D., Thanos, P. K., & Fowler, J. S. (2004) · Journal of Addictive Diseases · doi:10.1300/j069v23n03_04 · Cited by 502 · see citing works

Alcohol dependence is associated with blunted dopamine transmission in the ventral striatum

Martinez, D., Gil, R., Slifstein, M., Hwang, D.-R., Huang, Y., Perez, A., Kegeles, L., Talbot, P., Evans, S., Krystal, J., et al. (2005) · Biological Psychiatry · doi:10.1016/j.biopsych.2005.04.044 · Cited by 445 · see citing works

Neurobiology of addiction

Goodman, A. (2007) · Biochemical Pharmacology · doi:10.1016/j.bcp.2007.07.030 · Cited by 412 · see citing works

Role of dopamine in drug reinforcement and addiction in humans: results from imaging studies

Volkow, N. D., Fowler, J. S., & Wang, G.-J. (2002) · Behavioural Pharmacology · doi:10.1097/00008877-200209000-00008 · Cited by 398 · see citing works

Genetics of dopamine receptors and drug addiction: a comprehensive review

Foll, B. L., Gallo, A., Strat, Y. L., Lü, L., & Gorwood, P. A. P. M. (2009) · Behavioural Pharmacology · doi:10.1097/fbp.0b013e3283242f05 · Cited by 387 · see citing works

Endocannabinoid signaling system and brain reward: emphasis on dopamine

GARDNER, E. (2005) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2005.01.032 · Cited by 387 · see citing works

Cocaine supersensitivity and enhanced motivation for reward in mice lacking dopamine D2 autoreceptors

Bello, E. P., Mateo, Y., Gelman, D. M., Noaín, D., Shin, J. H., Low, M. J., Alvarez, V. A., Lovinger, D. M., & Rubinstein, M. (2011) · Nature Neuroscience · doi:10.1038/nn.2862 · Cited by 364 · see citing works

Why gamblers fail to win: a review of cognitive and neuroimaging findings in pathological gambling.

van Holst, R. V., van den Brink, W., Veltman, D., & Goudriaan, A. (2010) · Neuroscience and Biobehavioral Reviews · doi:10.1016/j.neubiorev.2009.07.007 · Cited by 416 · see citing works

Mechanisms involved in the neurotoxic, cognitive, and neurobehavioral effects of alcohol consumption during adolescence

Guerri, C., & Pascual, M. (2010) · Alcohol · doi:10.1016/j.alcohol.2009.10.003 · Cited by 344 · see citing works

The Neurobiological Underpinnings of Obesity and Binge Eating: A Rationale for Adopting the Food Addiction Model

Smith, D. G., & Robbins, T. W. (2012) · Biological Psychiatry · doi:10.1016/j.biopsych.2012.08.026 · Cited by 348 · see citing works

Repeated alcohol administration during adolescence causes changes in the mesolimbic dopaminergic and glutamatergic systems and promotes alcohol intake in the adult rat

Pascual, M., Boix, J., Felipo, V., & Guerri, C. (2008) · Journal of Neurochemistry · doi:10.1111/j.1471-4159.2008.05835.x · Cited by 318 · see citing works

Association of Seven Polymorphisms of the D2 Dopamine Receptor Gene with Brain Receptor-Binding Characteristics

Ritchie, T. L., & Noble, E. P. (2003) · Neurochemical Research · doi:10.1023/a:1021648128758 · Cited by 292 · see citing works

Brain DA D2 receptors predict reinforcing effects of stimulants in humans: Replication study

Volkow, N. D., Wang, G., Fowler, J. S., Thanos, P., Logan, J., Gatley, S. J., Gifford, A. J., Ding, Y., Wong, C., & Pappas, N. R. (2002) · Synapse · doi:10.1002/syn.10137 · Cited by 275 · see citing works

Neurobiology of addiction: treatment and public policy ramifications

Dackis, C. A., & O’Brien, C. P. (2005) · Nature Neuroscience · doi:10.1038/nn1105-1431 · Cited by 267 · see citing works

The dopamine hypothesis of drug addiction and its potential therapeutic value

Diana, M. (2011) · Frontiers in Psychiatry · doi:10.3389/fpsyt.2011.00064 · Cited by 251 · see citing works

The neurobiology of addiction

Uhl, G. R., Koob, G. F., & Cable, J. (2019) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13989 · Cited by 259 · see citing works

Early life adversity and health-risk behaviors: Proposed psychological and neural mechanisms

Duffy, K. A., McLaughlin, K. A., & Green, P. A. (2018) · Annals of the New York Academy of Sciences · doi:10.1111/nyas.13928 · Cited by 237 · see citing works

Dopamine and glucose, obesity, and reward deficiency syndrome

Blum, K., Thanos, P. K., & Gold, M. S. (2014) · Frontiers in Psychology · doi:10.3389/fpsyg.2014.00919 · Cited by 230 · see citing works

Imaging dopamine transmission in cocaine dependence: link between neurochemistry and response to treatment

Martinez, D., Carpenter, K. M., Liu, F., Slifstein, M., Broft, A., Friedman, A. C., Kumar, D., Van Heertum, R., Kleber, H. D., & Nunes, E. (2011) · American Journal of Psychiatry · doi:10.1176/appi.ajp.2010.10050748 · Cited by 212 · see citing works

Dopamine and alcoholism: neurobiological basis of ethanol abuse.

Tupala, E., & Tiihonen, J. (2004) · Progress in Neuro-psychopharmacology and Biological Psychiatry · doi:10.1016/j.pnpbp.2004.06.022 · Cited by 209 · see citing works

The<scp>D</scp>_2/3dopamine receptor in pathological gambling: a positron emission tomography study with [¹¹<scp>C</scp>]‐(+)‐propyl‐hexahydro‐naphtho‐oxazin and [¹¹<scp>C</scp>]raclopride

Boileau, I., Payer, D., Chugani, B., Lobo, D., Behzadi, A., Rusjan, P. M., Houle, S., Wilson, A. A., Warsh, J., Kish, S. J., et al. (2013) · Addiction · doi:10.1111/add.12066 · Cited by 190 · see citing works

Genetic Addiction Risk Score (GARS): Molecular Neurogenetic Evidence for Predisposition to Reward Deficiency Syndrome (RDS)

Blum, K., Oscar‐Berman, M., Demetrovics, Z., Barh, D., & Gold, M. S. (2014) · Molecular Neurobiology · doi:10.1007/s12035-014-8726-5 · Cited by 193 · see citing works

Activation instead of blocking mesolimbic dopaminergic reward circuitry is a preferred modality in the long term treatment of reward deficiency syndrome (RDS): a commentary

Blum, K., Chen, A. L., Chen, T. J. H., Braverman, E. R., Reinking, J. L., Blum, S. H., Cassel, K., Downs, B. W., Waite, R. L., Williams, L., et al. (2008) · Theoretical Biology and Medical Modelling · doi:10.1186/1742-4682-5-24 · Cited by 186 · see citing works

Effects of alcohol detoxification on dopamine D2 receptors in alcoholics: a preliminary study

Volkow, N. D., Wang, G., Maynard, L. J., Fowler, J. S., Jayne, B., Telang, F., Logan, J., Ding, Y., Gatley, S. J., HITZEMANN, R. J., et al. (2002) · Psychiatry Research Neuroimaging · doi:10.1016/s0925-4927(02)00087-2 · Cited by 185 · see citing works

CB1 Receptor Knockout Mice Display Reduced Ethanol-Induced Conditioned Place Preference and Increased Striatal Dopamine D2 Receptors

Houchi, H., Babovic, D., Pierrefiche, O., Ledent, C. A., Daoust, M., & Naassïla, M. (2004) · Neuropsychopharmacology · doi:10.1038/sj.npp.1300568 · Cited by 181 · see citing works

PET Imaging of Dopamine D2 Receptors in Monkey Models of Cocaine Abuse: Genetic Predisposition Versus Environmental Modulation

Nader, M. A., & Czoty, P. W. (2005) · American Journal of Psychiatry · doi:10.1176/appi.ajp.162.8.1473 · Cited by 177 · see citing works

Role of dopamine in the therapeutic and reinforcing effects of methylphenidate in humans: results from imaging studies

Volkow, N. (2002) · European Neuropsychopharmacology · doi:10.1016/s0924-977x(02)00104-9 · Cited by 217 · see citing works

The genetic epidemiology of substance use disorder: A review

Prom‐Wormley, E. C., Ebejer, J. L., Dick, D. M., & Bowers, M. S. (2017) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2017.06.040 · Cited by 173 · see citing works

Imaging addiction: D2 receptors and dopamine signaling in the striatum as biomarkers for impulsivity

Trifilieff, P., & Martinez, D. (2014) · Neuropharmacology · doi:10.1016/j.neuropharm.2013.06.031 · Cited by 171 · see citing works

Deficits in dopamine D2 receptors and pre-synaptic dopamine in heroin dependence: commonalities and differences with other types of addiction

Martinez, D., Saccone, P., Liu, F., Slifstein, M., Orlowska, D., Grassetti, A., Cook, S., Broft, A., Heertum, R. V. V., & Comer, S. (2011) · Biological Psychiatry · doi:10.1016/j.biopsych.2011.08.024 · Cited by 153 · see citing works

Biomarkers in Substance Use Disorders

Volkow, N. D., Koob, G., & Baler, R. (2015) · ACS Chemical Neuroscience · doi:10.1021/acschemneuro.5b00067 · Cited by 141 · see citing works

D2R DNA transfer into the nucleus accumbens attenuates cocaine self-administration in rats

Thanos, P. K., Michaelides, M., Umegaki, H., & Volkow, N. D. (2008) · Synapse · doi:10.1002/syn.20523 · Cited by 143 · see citing works

Food Addiction: Implications for the Diagnosis and Treatment of Overeating

Adams, R. C., Sedgmond, J., Maizey, L., Chambers, C., & Lawrence, N. (2019) · Nutrients · doi:10.3390/nu11092086 · Cited by 143 · see citing works

Circadian clock gene polymorphisms in alcohol use disorders and alcohol consumption

Kovanen, L., Saarikoski, S. T., Haukka, J., Pirkola, S., Aromaa, A., Lonnqvist, J., & Partonen, T. (2010) · Alcohol and Alcoholism · doi:10.1093/alcalc/agq035 · Cited by 138 · see citing works

Addictive potential of cannabinoids: the underlying neurobiology

Gardner, E. L. (2002) · Chemistry and Physics of Lipids · doi:10.1016/s0009-3084(02)00162-7 · Cited by 137 · see citing works

Distinct Synaptic Strengthening of the Striatal Direct and Indirect Pathways Drives Alcohol Consumption

Cheng, Y., Huang, C. C., Ma, T., Wei, X., Wang, X., Lu, J., & Wang, J. (2016) · Biological Psychiatry · doi:10.1016/j.biopsych.2016.05.016 · Cited by 131 · see citing works

Mechanisms of Shared Vulnerability to Post-traumatic Stress Disorder and Substance Use Disorders

Maria-Rios, C. E., & Morrow, J. D. (2020) · Frontiers in Behavioral Neuroscience · doi:10.3389/fnbeh.2020.00006 · Cited by 141 · see citing works

REVIEW: The UChA and UChB rat lines: metabolic and genetic differences influencing ethanol intake

Quintanilla, M. E., Israel, Y., Sapag, A., & Tampier, L. (2006) · Addiction Biology · doi:10.1111/j.1369-1600.2006.00030.x · Cited by 137 · see citing works

Effect of Exercise Training on Striatal Dopamine D2/D3 Receptors in Methamphetamine Users during Behavioral Treatment

Robertson, C. L., Ishibashi, K., Chudzynski, J. E., Mooney, L. J., Rawson, R. A., Dolezal, B. A., Cooper, C. B., Brown, A. K., Mandelkern, M. A., & London, E. D. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.331 · Cited by 136 · see citing works

Association of Specific Haplotypes of D2 Dopamine ReceptorGene With Vulnerability to Heroin Dependence in 2 Distinct Populations

Xu, K., Lichtermann, D., Lipsky, R. H., Franke, P. E., Liu, X., Hu, Y., Cao, L., Schwab, S. G., Wildenauer, D. B., Bau, C. H. D., et al. (2004) · Archives of General Psychiatry · doi:10.1001/archpsyc.61.6.597 · Cited by 129 · see citing works

DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking

Thanos, P. K., Taintor, N. B., Rivera, S. N., Umegaki, H., Ikari, H., Roth, G., Ingram, D. K., Hitzemann, R., Fowler, J. S., Gatley, S. J., et al. (2004) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000125270.30501.08 · Cited by 125 · see citing works

βγ Dimers Mediate Synergy of Dopamine D2 and Adenosine A2 Receptor-Stimulated PKA Signaling and Regulate Ethanol Consumption

Yao, L., Arolfo, M. P., Dohrman, D. P., Jiang, Z., Fan, P., Fuchs, S., Janak, P. H., Gordon, A. S., & Diamond, I. (2002) · Cell · doi:10.1016/s0092-8674(02)00763-8 · Cited by 123 · see citing works

Genetics of dopamine receptors and drug addiction

Gorwood, P. A. P. M., Strat, Y. L., Ramoz, N., Dubertret, C., Moalic, J., & Simonneau, M. (2012) · Human Genetics · doi:10.1007/s00439-012-1145-7 · Cited by 110 · see citing works

Striatal dopamine D2 receptor binding and dopamine release during cue-elicited craving in recently abstinent opiate-dependent males

Zijlstra, F., Booij, J., van den Brink, W., & Franken, I. H. A. (2008) · European Neuropsychopharmacology · doi:10.1016/j.euroneuro.2007.11.002 · Cited by 109 · see citing works

Effect of Menstrual Cycle Phase on Dopamine D2 Receptor Availability in Female Cynomolgus Monkeys

Czoty, P. W., Riddick, N. V., Gage, H. D., Sandridge, M., Nader, S. H., Garg, S., Bounds, M. C., Garg, P., & Nader, M. A. (2008) · Neuropsychopharmacology · doi:10.1038/npp.2008.3 · Cited by 109 · see citing works

Dopamine D2R DNA transfer in dopamine D2 receptor-deficient mice: effects on ethanol drinking

Thanos, P. K., Rivera, S. N., Weaver, K., Grandy, D. K., Rubinstein, M., Umegaki, H., Wang, G. J., Hitzemann, R., & Volkow, N. D. (2005) · Life Sciences · doi:10.1016/j.lfs.2004.10.061 · Cited by 108 · see citing works

Advances in molecular genetics and the prevention and treatment of substance misuse: Implications of association studies of the A1 allele of the D2 dopamine receptor gene

Young, R. M., Lawford, B. R., Nutting, A., & Noble, E. P. (2004) · Addictive Behaviors · doi:10.1016/j.addbeh.2004.06.012 · Cited by 105 · see citing works

Effects of chronic oral methylphenidate on cocaine self-administration and striatal dopamine D2 receptors in rodents

Thanos, P. K., Michaelides, M., Benveniste, H., Wang, G. J., & Volkow, N. D. (2007) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2007.05.020 · Cited by 100 · see citing works

The selective dopamine D3 receptor antagonist SB-277011-A attenuates ethanol consumption in ethanol preferring (P) and non-preferring (NP) rats

Thanos, P. K., KATANA, J., ASHBYJR, C., Michaelides, M., Gardner, E., Heidbreder, C. A., & Volkow, N. D. (2005) · Pharmacology Biochemistry and Behavior · doi:10.1016/j.pbb.2005.03.013 · Cited by 98 · see citing works

Prefrontal cortical–striatal dopamine receptor m RNA expression predicts distinct forms of impulsivity

Simon, N. W., Beas, B. S., Montgomery, K. S., Haberman, R. P., Bizon, J. L., & Setlow, B. (2013) · European Journal of Neuroscience · doi:10.1111/ejn.12191 · Cited by 92 · see citing works

Positron emission tomography and single-photon emission computed tomography in substance abuse research.

Volkow, N., Fowler, J., & Wang, G.-J. (2003) · Seminars in nuclear medicine · doi:10.1053/snuc.2003.127300 · Cited by 89 · see citing works

The gut in the brain: the effects of bariatric surgery on alcohol consumption

Blackburn, A. N., Hajnal, A. S., & Leggio, L. (2016) · Addiction Biology · doi:10.1111/adb.12436 · Cited by 92 · see citing works

The role of learning-related dopamine signals in addiction vulnerability

Huys, Q. J. M., Tobler, P. N., Hasler, G., & Flagel, S. B. (2014) · Progress in brain research · doi:10.1016/b978-0-444-63425-2.00003-9 · Cited by 87 · see citing works

Genetic influences on quantity of alcohol consumed by adolescents and young adults

Hopfer, C. J., Timberlake, D. S., Haberstick, B. C., Lessem, J. M., Ehringer, M. A., Smolen, A., & Hewitt, J. K. (2004) · Drug and Alcohol Dependence · doi:10.1016/j.drugalcdep.2004.11.003 · Cited by 88 · see citing works

Alcohol Reward Is Increased after Roux-en-Y Gastric Bypass in Dietary Obese Rats with Differential Effects following Ghrelin Antagonism

Hajnal, A. S., Zharikov, A., Polston, J. E., Fields, M. R., Tomasko, J. M., Rogers, A. M., Volkow, N. D., & Thanos, P. K. (2012) · PLoS ONE · doi:10.1371/journal.pone.0049121 · Cited by 86 · see citing works

Midbrain circuit regulation of individual alcohol drinking behaviors in mice

Juarez, B., Morel, C., Ku, S. M., Liu, Y., Zhang, H., Montgomery, S. E., Gregoire, H., Ribeiro, E., Crumiller, M., Roman-Ortiz, C., et al. (2017) · Nature Communications · doi:10.1038/s41467-017-02365-8 · Cited by 83 · see citing works

Cocaine abuse and sensitization of striatal dopamine transmission: A critical review of the preclinical and clinical imaging literature

Narendran, R., & Martinez, D. (2008) · Synapse · doi:10.1002/syn.20566 · Cited by 88 · see citing works

Dopamine-Based Reward Circuitry Responsivity, Genetics, and Overeating

Stice, E. M., Yokum, S., Zald, D. H., & Dagher, A. (2010) · Current topics in behavioral neurosciences · doi:10.1007/7854_2010_89 · Cited by 81 · see citing works

Genotrim™, a DNA-customized nutrigenomic product, targets genetic factors of obesity: Hypothesizing a dopamine–glucose correlation demonstrating reward deficiency syndrome (RDS)

Blum, K., Chen, T. J. H., Meshkin, B., Downs, B. W., Gordon, C. A., Blum, S. H., Mangucci, J. F., Braverman, E. R., Arcuri, V., Deutsch, R., et al. (2006) · Medical Hypotheses · doi:10.1016/j.mehy.2006.08.041 · Cited by 78 · see citing works

Innately low D2 receptor availability is associated with high novelty-seeking and enhanced behavioural sensitization to amphetamine

Tournier, B. B., Steimer, T. J., Millet, P., Sallanon, M. M., Vallet, P. G., Ibañez, V., & Ginovart, N. (2013) · The International Journal of Neuropsychopharmacology · doi:10.1017/s1461145713000205 · Cited by 76 · see citing works

Neurogenetics and Nutrigenomics of Neuro-Nutrient Therapy for Reward Deficiency Syndrome (RDS): Clinical Ramifications as a Function of Molecular Neurobiological Mechanisms

Blum, K. (2013) · Journal of Addiction Research &amp; Therapy · doi:10.4172/2155-6105.1000139 · Cited by 73 · see citing works

The Molecular Neurobiology of Twelve Steps Program &amp; Fellowship: Connecting the Dots for Recovery

Blum, K., Thompson, B., Demotrovics, Z., Femino, J., Giordano, J., Oscar-Berman, M., Teitelbaum, S., Smith, D. E., Roy, A. K., Agan, G., et al. (2015) · Journal of Reward Deficiency Syndrome · doi:10.17756/jrds.2015-008 · Cited by 73 · see citing works

Clinically Combating Reward Deficiency Syndrome (RDS) with Dopamine Agonist Therapy as a Paradigm Shift: Dopamine for Dinner?

Blum, K., Febo, M., Thanos, P. K., Baron, D. A., Fratantonio, J. L., & Gold, M. S. (2015) · Molecular Neurobiology · doi:10.1007/s12035-015-9110-9 · Cited by 68 · see citing works

Nutrigenomic targeting of carbohydrate craving behavior: Can we manage obesity and aberrant craving behaviors with neurochemical pathway manipulation by Immunological Compatible Substances (nutrients) using a Genetic Positioning System (GPS) Map?

Downs, B. W., Chen, A. L., Chen, T. J. H., Waite, R. L., Braverman, E. R., Kerner, M. M., Braverman, D., Rhoades, P., Prihoda, T. J., Palomo, T., et al. (2009) · Medical Hypotheses · doi:10.1016/j.mehy.2009.02.037 · Cited by 68 · see citing works

Reverse Pharmacogenetic Modulation of the Nucleus Accumbens Reduces Ethanol Consumption in a Limited Access Paradigm

Cassataro, D., Bergfeldt, D., Malekian, C., Snellenberg, J. X. V., Thanos, P. K., Fishell, G., & Sjulson, L. (2013) · Neuropsychopharmacology · doi:10.1038/npp.2013.184 · Cited by 61 · see citing works

Addictions Neuroclinical Assessment: A reverse translational approach

Kwako, L. E., Momenan, R., Grodin, E. N., Litten, R. Z., Koob, G. F., & Goldman, D. A. (2017) · Neuropharmacology · doi:10.1016/j.neuropharm.2017.03.006 · Cited by 62 · see citing works

Applications of positron emission tomography in animal models of neurological and neuropsychiatric disorders

Virdee, K., Cumming, P. D., Caprioli, D., Jupp, B., Rominger, A., Aigbirhio, F. I., Fryer, T. D., Riss, P. J., & Dalley, J. W. (2012) · Neuroscience & Biobehavioral Reviews · doi:10.1016/j.neubiorev.2012.01.009 · Cited by 60 · see citing works

Circuit selectivity in drug versus natural reward seeking behaviors

Nall, R. W., Heinsbroek, J. A., Nentwig, T. B., Kalivas, P. W., & Bobadilla, A. (2021) · Journal of Neurochemistry · doi:10.1111/jnc.15297 · Cited by 59 · see citing works

[18F]fallypride PET measurement of striatal and extrastriatal dopamine D2/3 receptor availability in recently abstinent alcoholics

Rominger, A., Cumming, P. D., Xiong, G., Koller, G., Böning, G., Wulff, M., Zwergal, A., Förster, S., Reilhac, A., Munk, O. L., et al. (2011) · Addiction Biology · doi:10.1111/j.1369-1600.2011.00355.x · Cited by 59 · see citing works

Narcotic antagonists in drug dependence: pilot study showing enhancement of compliance with SYN-10, amino-acid precursors and enkephalinase inhibition therapy

Chen, T. J. H., Blum, K., Payte, J. T., Schoolfield, J. D., Hopper, D., Stanford, M., & Braverman, E. R. (2004) · Medical Hypotheses · doi:10.1016/j.mehy.2004.02.051 · Cited by 59 · see citing works

Association of the −141C Del variant of the dopamine D2 receptor (DRD2) with positive family history and suicidality in German alcoholics

Johann, M., Putzhammer, A., Eichhammer, P., & Wodarz, N. (2004) · American Journal of Medical Genetics Part B Neuropsychiatric Genetics · doi:10.1002/ajmg.b.30085 · Cited by 59 · see citing works

High intensity interval training exercise increases dopamine D2 levels and modulates brain dopamine signaling

Tyler, J. R., Podaras, M., Richardson, B., Roeder, N. M., Hammond, N., Hamilton, J., Blum, K., Gold, M. S., Baron, D. A., & Thanos, P. K. (2023) · Frontiers in Public Health · doi:10.3389/fpubh.2023.1257629 · Cited by 56 · see citing works

Acute Intravenous Synaptamine Complex Variant KB220™ “Normalizes” Neurological Dysregulation in Patients during Protracted Abstinence from Alcohol and Opiates as Observed Using Quantitative Electroencephalographic and Genetic Analysis for Reward Polymorphisms: Part 1, Pilot Study with 2 Case Reports

Miller, D. K., Bowirrat, A., Manka, M., Miller, M., Stokes, S., Manka, D., Allen, C., Gant, C. E., Downs, B. W., Smolen, A., et al. (2010) · Postgraduate Medicine · doi:10.3810/pgm.2010.11.2236 · Cited by 57 · see citing works

Blunted Dopamine Transmission in Addiction: Potential Mechanisms and Implications for Behavior.

Trifilieff, P., Ducrocq, F., van der Veldt, S., & Martinez, D. (2017) · Seminars in nuclear medicine · doi:10.1053/j.semnuclmed.2016.09.003 · Cited by 47 · see citing works

Pharmacotherapy, Pharmacogenomics, and The Future of Alcohol Dependence Treatment, Part 2

Kenna, G. A., McGeary, J. E., & Swift, R. M. (2004) · American Journal of Health-System Pharmacy · doi:10.1093/ajhp/61.22.2380 · Cited by 57 · see citing works

Association of the dopamine D2 receptor gene with alcohol dependence: haplotypes and subgroups of alcoholics as key factors for understanding receptor function

Kraschewski, A., Reese, J., Anghelescu, I. G., Winterer, G., Schmidt, L. G., Gallinat, J., Finckh, U., Rommelspacher, H., & Wernicke, C. (2009) · Pharmacogenetics and Genomics · doi:10.1097/fpc.0b013e32832d7fd3 · Cited by 56 · see citing works

8.3 Imaging Dopamine’s Role in Drug Abuse and Addiction

Volkow, N. D., Fowler, J. S., Wang, G., Telang, F., & Baler, R. (2009) · Oxford University Press eBooks · doi:10.1093/acprof:oso/9780195373035.003.0028 · Cited by 58 · see citing works

NEUROGENETIC IMPAIRMENTS OF BRAIN REWARD CIRCUITRY LINKS TO REWARD DEFICIENCY SYNDROME (RDS) AS EVIDENCED BY GENETIC ADDICTION RISK SCORE (GARS): A CASE STUDY

Blum, K., Han, D. C., Hauser, M., Downs, B. W., Giordano, J., Borsten, J., Winchell, E., Simpatico, T. A., Madigan, M. A., Barh, D., et al. (2013) · Cited by 52 · see citing works

On the Integration of Alcohol‐Related Quantitative Trait Loci and Gene Expression Analyses

HITZEMANN, R. J., Reed, C. L., Malmanger, B., Lawler, M. P., Hitzemann, B. A., Cunningham, B., McWeeney, S. K., Belknap, J. K., Harrington, C. A., Buck, K. J., et al. (2004) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000139827.86749.da · Cited by 52 · see citing works

Neurogenetics and Clinical Evidence for the Putative Activation of the Brain Reward Circuitry by a Neuroadaptagen: Proposing an Addiction Candidate Gene Panel Map

Chen, T. J. H., Blum, K., Chen, A. L., Bowirrat, A., Downs, W. B., Madigan, M. A., Waite, R. L., Bailey, J. A., Kerner, M., Yeldandi, S., et al. (2011) · Journal of Psychoactive Drugs · doi:10.1080/02791072.2011.587393 · Cited by 51 · see citing works

Adolescent Drug Addiction Treatment and Weight Gain

Hodgkins, C. C., Cahill, K. S., Seraphine, A. E., Frost-Pineda, K., & Gold, M. S. (2004) · Journal of Addictive Diseases · doi:10.1300/j069v23n03_05 · Cited by 51 · see citing works

Association between DRD2/ANKK1 TaqIA polymorphism and common illicit drug dependence: Evidence from a meta-analysis

Deng, X., Jiang, H., Ma, Y., Gao, Q. F., Zhang, B., Mu, B., Zhang, L.-X., Zhang, W., Er, Z.-E. M., Xie, Y., et al. (2014) · Human Immunology · doi:10.1016/j.humimm.2014.12.005 · Cited by 49 · see citing works

Upregulation of Dopamine D2 Receptors in the Nucleus Accumbens Indirect Pathway Increases Locomotion but Does Not Reduce Alcohol Consumption

Gallo, E. F., Salling, M. C., Feng, B., Morón, J. A., Harrison, N. L., Javitch, J. A., & Kellendonk, C. (2015) · Neuropsychopharmacology · doi:10.1038/npp.2015.11 · Cited by 48 · see citing works

DRD2 gene transfer into the nucleus accumbens core of the alcohol preferring and nonpreferring rats attenuates alcohol drinking

Thanos, P. K., Taintor, N. B., Rivera, S. N., Umegaki, H., Ikari, H., Roth, G., Ingram, D. K., Hitzemann, R., Fowler, J. S., Gatley, S. J., et al. (2004) · Alcoholism Clinical and Experimental Research · doi:10.1097/01.alc.0000125270.30501.08 · Cited by 125 · see citing works

Evaluation of A1 Allele of the DRD2 Gene in Rat Model and Human

Hassanzadeh, Z., Mashayekhi, M., Siamak, S., & ughchian (2015) · Der pharmacia lettre

Dopamine D2R DNA transfer in dopamine D2 receptor-deficient mice: effects on ethanol drinking

Thanos, P. K., Rivera, S. N., Weaver, K., Grandy, D. K., Rubinstein, M., Umegaki, H., Wang, G. J., Hitzemann, R., & Volkow, N. D. (2005) · Life Sciences · doi:10.1016/j.lfs.2004.10.061 · Cited by 108 · see citing works

Therapy for alcoholic rats

Weitzman, J. B. (2001) · Trends in Molecular Medicine · doi:10.1016/s1471-4914(01)02203-1

Alcohol preference and sensitivity are markedly reduced in mice lacking dopamine D2 receptors

Phillips, T. J., Brown, K. J., Burkhart‐Kasch, S., Wenger, C. D., Kelly, M. A., Rubinstein, M., Grandy, D. K., & Low, M. J. (1998) · Nature Neuroscience · doi:10.1038/2843 · Cited by 272 · see citing works