Galluzzi, Lorenzo

Mitochondrial DNA drives abscopal responses to radiation that are inhibited by autophagy

Yamazaki, T., Kirchmair, A., Sato, A., Buqué, A., Rybstein, M., Petroni, G., Bloy, N., Finotello, F., Stafford, L., Navarro Manzano, E., et al. (2020) · Nature Immunology

Autophagy in Disease and TherapyCancer Immunotherapy and Biomarkers

Cited by 359

Caspases Connect Cell-Death Signaling to Organismal Homeostasis

Galluzzi, L., López-Soto, A., Kumar, S., & Kroemer, G. (2016) · Immunity

Cell death mechanisms and regulationInflammasome and immune disorders

Cited by 350

Molecular mechanisms of cell death: central implication of ATP synthase in mitochondrial permeability transition

Bonora, M., Wieckowski, M. R., Chinopoulos, C., Kepp, O., Kroemer, G., Galluzzi, L., & Pinton, P. (2015) · Oncogene

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 330

Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy

Galluzzi, L., Bravo-San Pedro, J. M., Demaria, S., Formenti, S. C., & Kroemer, G. (2017) · Nature Reviews Clinical Oncology

Autophagy in Disease and TherapyCancer Immunotherapy and Biomarkers

Cited by 314

The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1

Vicencio, J. M., Ortiz, C., Criollo, A., Jones, A. W. E., Kepp, O., Galluzzi, L., Joza, N., Vitale, I., Morselli, E., Tailler, M., et al. (2009) · Cell Death & Differentiation

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 289

Trial watch: STING agonists in cancer therapy

Le Naour, J., Zitvogel, L., Galluzzi, L., Vacchelli, E., & Kroemer, G. (2020) · OncoImmunology

interferon and immune responsesImmunotherapy and Immune Responses

Cited by 289

Cytoplasmic STAT3 represses autophagy by inhibiting PKR activity

Shen, S., Niso-Santano, M., Adjemian, S., Takehara, T., Malik, S. A., Minoux, H., Souquere, S., Mariño, G., Lachkar, S., Senovilla, L., et al. (2012) · Molecular Cell

Autophagy in Disease and TherapyCytokine Signaling Pathways and Interactions

Cited by 285

Molecular mechanisms of regulated necrosis

Galluzzi, L., Kepp, O., Krautwald, S., Kroemer, G., & Linkermann, A. (2014) · Seminars in Cell & Developmental Biology

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 258

Cytosolic DNA Sensing in Organismal Tumor Control

Vanpouille-Box, C., Demaria, S., Formenti, S. C., & Galluzzi, L. (2018) · Cancer Cell

interferon and immune responsesImmunotherapy and Immune Responses

Cited by 250

Trial watch: TLR3 agonists in cancer therapy

Le Naour, J., Galluzzi, L., Zitvogel, L., Kroemer, G., & Vacchelli, E. (2020) · OncoImmunology

Immunotherapy and Immune ResponsesImmune Response and Inflammation

Cited by 239

Organelle-specific initiation of cell death

Galluzzi, L., Bravo-San Pedro, J. M., & Kroemer, G. (2014) · Nature Cell Biology

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 239

Immune checkpoint inhibitor–associated myocarditis: manifestations and mechanisms

Moslehi, J., Lichtman, A. H., Sharpe, A. H., Galluzzi, L., & Kitsis, R. N. (2021) · Journal of Clinical Investigation

Cancer Immunotherapy and BiomarkersViral Infections and Immunology Research

Cited by 237

Ca2+ Fluxes and Cancer

Marchi, S., Giorgi, C., Galluzzi, L., & Pinton, P. (2020) · Molecular Cell

Ion Channels and ReceptorsCalcium signaling and nucleotide metabolism

Cited by 235

Autophagy in acute brain injury

Galluzzi, L., Bravo-San Pedro, J. M., Blomgren, K., & Kroemer, G. (2016) · Nature Reviews Neuroscience

Autophagy in Disease and TherapyTraumatic Brain Injury and Neurovascular Disturbances

Cited by 234

Autophagy mediates pharmacological lifespan extension by spermidineand resveratrol

Morselli, E., Galluzzi, L., Kepp, O., Criollo, A., Maiuri, M. C., Tavernarakis, N., Madeo, F., & Kroemer, G. (2009) · Aging

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 213

Immunomodulation by targeted anticancer agents

Petroni, G., Buqué, A., Zitvogel, L., Kroemer, G., & Galluzzi, L. (2021) · Cancer Cell

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 212

Mitochondrial Permeability Transition: New Findings and Persisting Uncertainties

Izzo, V., Bravo-San Pedro, J. M., Sica, V., Kroemer, G., & Galluzzi, L. (2016) · Trends in Cell Biology

Mitochondrial Function and PathologyCell death mechanisms and regulation

Cited by 205

Organelle-Specific Initiation of Autophagy

Sica, V., Galluzzi, L., Bravo-San Pedro, J. M., Izzo, V., Maiuri, M. C., & Kroemer, G. (2015) · Molecular Cell

Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism

Cited by 205

Pharmacological modulation of nucleic acid sensors - therapeutic potential and persisting obstacles

Vanpouille-Box, C., Hoffmann, J. A., & Galluzzi, L. (2019) · Nature Reviews Drug Discovery

interferon and immune responsesImmune Response and Inflammation

Cited by 183

Regulated cell death and adaptive stress responses

Galluzzi, L., Bravo-San Pedro, J. M., Kepp, O., & Kroemer, G. (2016) · Cellular and Molecular Life Sciences

Cell death mechanisms and regulationAutophagy in Disease and Therapy

Cited by 177

Cisplatin Resistance Associated with PARP Hyperactivation

Michels, J., Vitale, I., Galluzzi, L., Adam, J., Olaussen, K. A., Kepp, O., Senovilla, L., Talhaoui, I., Guegan, J., Enot, D. P., et al. (2013) · Cancer Research

PARP inhibition in cancer therapyCell death mechanisms and regulation

Cited by 176

Immunological Mechanisms Underneath the Efficacy of Cancer Therapy

Galluzzi, L., Zitvogel, L., & Kroemer, G. (2016) · Cancer Immunology Research

Cancer Immunotherapy and BiomarkersImmunotherapy and Immune Responses

Cited by 175

Mitochondrial control of the NLRP3 inflammasome

Kepp, O., Galluzzi, L., & Kroemer, G. (2011) · Nature Immunology

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 168

Immunomodulation by anticancer cell cycle inhibitors

Petroni, G., Formenti, S. C., Chen-Kiang, S., & Galluzzi, L. (2020) · Nature Reviews Immunology

Cancer Immunotherapy and BiomarkersAdvanced Breast Cancer Therapies

Cited by 163