Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy

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Induction of the Vitamin D Receptor Attenuates Autophagy Dysfunction-Mediated Cell Death Following Traumatic Brain Injury

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Autophagy and Viruses: Adversaries or Allies?

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Bcl-2 Antiapoptotic Proteins Inhibit Beclin 1-Dependent Autophagy

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Immunogenic cell death in cancer and infectious disease

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The role of autophagy during the early neonatal starvation period

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Immune checkpoint targeting in cancer therapy: toward combination strategies with curative potential

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Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway

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Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

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Autophagy in infection, inflammation and immunity

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Immunological effects of conventional chemotherapy and targeted anticancer agents

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Cancer cachexia: understanding the molecular basis

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Cancer metabolism: a therapeutic perspective

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Autophagy modulation as a potential therapeutic target for diverse diseases

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Autophagy-Dependent Anticancer Immune Responses Induced by Chemotherapeutic Agents in Mice

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Activation of autophagy by inflammatory signals limits IL-1β production by targeting ubiquitinated inflammasomes for destruction

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Autophagy-deficient mice develop multiple liver tumors

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The autophagosome: origins unknown, biogenesis complex

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Mitochondria and the Autophagy–Inflammation–Cell Death Axis in Organismal Aging

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Autophagy in malignant transformation and cancer progression

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VEGF-A modulates expression of inhibitory checkpoints on CD8+ T cells in tumors

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Autophagy inhibition enhances therapy-induced apoptosis in a Myc-induced model of lymphoma

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Pancreatic stellate cells support tumour metabolism through autophagic alanine secretion

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Nutrient-sensing mechanisms and pathways

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Autophagy mediates the mitotic senescence transition

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Essential versus accessory aspects of cell death: recommendations of the NCCD 2015

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Autophagy at the crossroads of catabolism and anabolism

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Endogenous HMGB1 regulates autophagy

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Metabolic control of autophagy

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Compromised autophagy and neurodegenerative diseases

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Metabolic Control of Longevity

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Fasting Cycles Retard Growth of Tumors and Sensitize a Range of Cancer Cell Types to Chemotherapy

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p53 status determines the role of autophagy in pancreatic tumour development

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To Be or Not to Be? How Selective Autophagy and Cell Death Govern Cell Fate

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Live to die another way: modes of programmed cell death and the signals emanating from dying cells

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Radiation fosters dose-dependent and chemotherapy-induced immunogenic cell death

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A critical role for the autophagy gene Atg5 in T cell survival and proliferation

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Inflammasomes in carcinogenesis and anticancer immune responses

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Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis

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Autophagy is required for glucose homeostasis and lung tumor maintenance

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Caloric restriction mimetics enhance anticancer immunosurveillance

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EGFR-Mediated Beclin 1 Phosphorylation in Autophagy Suppression, Tumor Progression, and Tumor Chemoresistance

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A phase I/II trial of hydroxychloroquine in conjunction with radiation therapy and concurrent and adjuvant temozolomide in patients with newly diagnosed glioblastoma multiforme

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Regulation of autophagy by cytosolic acetyl-coenzyme A

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Autophagy-Mediated Tumor Promotion

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Autophagy is critical for pancreatic tumor growth and progression in tumors with p53 alterations

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Hypoxia-Induced Autophagy Promotes Tumor Cell Survival and Adaptation to Antiangiogenic Treatment in Glioblastoma

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Classification of current anticancer immunotherapies

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HMGB1 release and redox regulates autophagy and apoptosis in cancer cells

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Autophagy and cellular immune responses

Ma, Y., Galluzzi, L., Zitvogel, L., & Kroemer, G. (2013) · Immunity · doi:10.1016/j.immuni.2013.07.017 · Cited by 447 · see citing works

A dual role for autophagy in a murine model of lung cancer

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Autophagy Sustains Mitochondrial Glutamine Metabolism and Growth of <i>Braf</i> V600E–Driven Lung Tumors

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Combined MTOR and autophagy inhibition

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Autophagy inhibitor Lys05 has single-agent antitumor activity and reproduces the phenotype of a genetic autophagy deficiency

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Tumor Vessel Normalization by Chloroquine Independent of Autophagy

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Fasting-Mimicking Diet Reduces HO-1 to Promote T Cell-Mediated Tumor Cytotoxicity

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Suppression of autophagy by FIP200 deletion inhibits mammary tumorigenesisPreprint

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Chloroquine sensitizes breast cancer cells to chemotherapy independent of autophagy

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Mechanistic insights into selective autophagy pathways: lessons from yeast

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Phase II and Pharmacodynamic Study of Autophagy Inhibition Using Hydroxychloroquine in Patients With Metastatic Pancreatic Adenocarcinoma

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Combined autophagy and proteasome inhibition

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Beclin 1 and autophagy are required for the tumorigenicity of breast cancer stem-like/progenitor cells

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Phase I trial of hydroxychloroquine with dose-intense temozolomide in patients with advanced solid tumors and melanoma

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Autophagy is a critical regulator of memory CD8+ T cell formation

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Caspases Connect Cell-Death Signaling to Organismal Homeostasis

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Granzyme B degradation by autophagy decreases tumor cell susceptibility to natural killer-mediated lysis under hypoxia

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Radiation as an immunological adjuvant: current evidence on dose and fractionation

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Inhibition of autophagy augments 5-fluorouracil chemotherapy in human colon cancer in vitro and in vivo model

Li, J., Hou, N., Faried, A., Tsutsumi, S., & Kuwano, H. (2010) · European Journal of Cancer · doi:10.1016/j.ejca.2010.02.021 · Cited by 318 · see citing works

Metabolic reprogramming of cancer-associated fibroblasts by TGF-β drives tumor growth: Connecting TGF-β signaling with “Warburg-like” cancer metabolism and L-lactate production

Guido, C., Whitaker‐Menezes, D., Capparelli, C., Balliet, R. M., Zhao, L., Pestell, R. G., Howell, A., Aquila, S., Andò, S., Martinez‐Outschoorn, U., et al. (2012) · Cell Cycle · doi:10.4161/cc.21384 · Cited by 316 · see citing works

ROS-induced autophagy in cancer cells assists in evasion from determinants of immunogenic cell death

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Efficient Cross-presentation Depends on Autophagy in Tumor Cells

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Autophagy inhibition suppresses pulmonary metastasis of HCC in mice via impairing anoikis resistance and colonization of HCC cells

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Combined autophagy and HDAC inhibition

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Inhibition of autophagy enhances the anticancer activity of silver nanoparticles

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Autophagy regulates selective HMGB1 release in tumor cells that are destined to die

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The effects of short-term fasting on tolerance to (neo) adjuvant chemotherapy in HER2-negative breast cancer patients: a randomized pilot study

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Blocking Hypoxia-Induced Autophagy in Tumors Restores Cytotoxic T-Cell Activity and Promotes Regression

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A novel ATG4B antagonist inhibits autophagy and has a negative impact on osteosarcoma tumors

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Dnase2a deficiency uncovers lysosomal clearance of damaged nuclear DNA via autophagy

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Autophagy in acute brain injury

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Autophagy Inhibition Sensitizes Colon Cancer Cells to Antiangiogenic and Cytotoxic Therapy

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Molecular mechanisms of cell death: recommendations of the nomenclature committee on cell death 2018.

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Macrophages and metabolism in the tumor microenvironment

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Molecular definitions of autophagy and related processes

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Autophagy in major human diseases

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Mitochondrial metabolism and cancer

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The Roles of Autophagy in Cancer

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Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles

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Advantages of targeting the tumor immune microenvironment over blocking immune checkpoint in cancer immunotherapy

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Lactate: A Metabolic Driver in the Tumour Landscape

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Linking cellular stress responses to systemic homeostasis

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Lactate and lactylation in cancer

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Engineering of a Nanosized Biocatalyst for Combined Tumor Starvation and Low-Temperature Photothermal Therapy

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The spectrum of T cell metabolism in health and disease

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Autophagy and cancer stem cells: molecular mechanisms and therapeutic applications

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Mitochondrial DNA drives abscopal responses to radiation that are inhibited by autophagy

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Metal Drugs and the Anticancer Immune Response

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Metal-based NanoEnhancers for Future Radiotherapy: Radiosensitizing and Synergistic Effects on Tumor Cells

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An ER‐Targeting Iridium(III) Complex That Induces Immunogenic Cell Death in Non‐Small‐Cell Lung Cancer

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The autophagic network and cancer

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Trial watch: Immunogenic cell death induction by anticancer chemotherapeutics

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The circular RNA ACR attenuates myocardial ischemia/reperfusion injury by suppressing autophagy via modulation of the Pink1/ FAM65B pathway

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Salidroside induces apoptosis and protective autophagy in human gastric cancer AGS cells through the PI3K/Akt/mTOR pathway

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WNT Signaling in Cancer Immunosurveillance

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Trial watch: chemotherapy-induced immunogenic cell death in immuno-oncology

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Sonodynamic therapy-derived multimodal synergistic cancer therapy

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Autophagy in stem cells: repair, remodelling and metabolic reprogramming

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Photodynamic Therapy and Immunity: An Update

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mTOR-mediated cancer drug resistance suppresses autophagy and generates a druggable metabolic vulnerability

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Autophagy and intermittent fasting: the connection for cancer therapy?

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Targeting oncogene and non-oncogene addiction to inflame the tumour microenvironment

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Radiotherapy orchestrates natural killer cell dependent antitumor immune responses through CXCL8

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Research progress on morphology and mechanism of programmed cell death

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Recent Insights into the Mitochondrial Role in Autophagy and Its Regulation by Oxidative Stress

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Green Synthesis of Silver Nanoparticles Using Annona muricata Extract as an Inducer of Apoptosis in Cancer Cells and Inhibitor for NLRP3 Inflammasome via Enhanced Autophagy

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Stress-induced cellular responses in immunogenic cell death: Implications for cancer immunotherapy

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A novel anti-HER2 anthracycline-based antibody-drug conjugate induces adaptive anti-tumor immunity and potentiates PD-1 blockade in breast cancer

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FOXM1 contributes to docetaxel resistance in castration-resistant prostate cancer by inducing AMPK/mTOR-mediated autophagy

Lin, J., Wang, W., Hu, T., Zhu, G., Li, L.-N., Zhang, C.-Y., Xu, Z., Yu, H.-B., Wu, H., & Zhu, J. (2019) · Cancer Letters · doi:10.1016/j.canlet.2019.11.014 · Cited by 136 · see citing works

circHIPK3 promotes oxaliplatin-resistance in colorectal cancer through autophagy by sponging miR-637

Zhang, Y., Li, C., Liu, X., Wang, Y., Zhao, R., Yang, Y., Zheng, X. M., Zhang, Y., & Zhang, X. (2019) · EBioMedicine · doi:10.1016/j.ebiom.2019.09.051 · Cited by 133 · see citing works

NF‐κB targeting for overcoming tumor resistance and normal tissues toxicity

Mortezaee, K., Najafi, M., Farhood, B., Ahmadi, A., Shabeeb, D., & Musa, A. E. (2019) · Journal of Cellular Physiology · doi:10.1002/jcp.28504 · Cited by 131 · see citing works

Ivermectin, a potential anticancer drug derived from an antiparasitic drug

Tang, M., Hu, X., Wang, Y., Yao, X., Zhang, W., Yu, C., Cheng, F., Li, J., & Fang, Q. (2020) · Pharmacological Research · doi:10.1016/j.phrs.2020.105207 · Cited by 133 · see citing works

Trial Watch: Immunomodulatory monoclonal antibodies for oncological indications

Buqué, A., Bloy, N., Aranda, F., Castoldi, F., Eggermont, A. M. M., Cremer, I., Fridman, W. H., Fucikova, J. P., Galon, J., Marabelle, A., et al. (2015) · OncoImmunology · doi:10.1080/2162402x.2015.1008814 · Cited by 130 · see citing works

Targeting autophagy in cancer stem cells as an anticancer therapy

Lei, Y., Zhang, D., Yu, J., Dong, H. F., Zhang, J., & Yang, S. (2017) · Cancer Letters · doi:10.1016/j.canlet.2017.02.012 · Cited by 125 · see citing works

Progress of engineered bacteria for tumor therapy

Fan, J., Niu, M., Qin, Y., Sun, Y., & Zhang, X. (2022) · Advanced Drug Delivery Reviews · doi:10.1016/j.addr.2022.114296 · Cited by 126 · see citing works

Autophagy and Hallmarks of Cancer

Huang, T., Song, X., Yang, Y., Wan, X., Alvarez, A. A., Sastry, N. G., Feng, H., Hu, B., & Cheng, S. (2018) · Critical Reviews™ in Oncogenesis · doi:10.1615/critrevoncog.2018027913 · Cited by 116 · see citing works

Targeting regulated cell death in tumor nanomedicines

Zeng, Q., Ma, X., Song, Y., Chen, Q., Jiao, Q., & Zhou, L. (2021) · Theranostics · doi:10.7150/thno.67932 · Cited by 118 · see citing works

Rapamycin inhibits proliferation and induces autophagy in human neuroblastoma cells

Lin, X., Han, L., Weng, J., Wang, K., & Chen, T. (2018) · Bioscience Reports · doi:10.1042/bsr20181822 · Cited by 110 · see citing works

LncRNA SNHG6 promotes chemoresistance through ULK1-induced autophagy by sponging miR-26a-5p in colorectal cancer cells

Wang, X., Lan, Z., He, J., Lai, Q., Yao, X., Li, Q., Liu, Y., Lai, H., Gu, C.-C., Yan, Q., et al. (2019) · Cancer Cell International · doi:10.1186/s12935-019-0951-6 · Cited by 108 · see citing works

Autophagy: Supporting cellular and organismal homeostasis by self-eating

Eskelinen, E. (2019) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2019.03.010 · Cited by 106 · see citing works

The role of Wnt signaling pathway in tumor metabolic reprogramming

Mo, Y., Wang, Y., Zhang, L., Yang, L., Zhou, M., Li, X., Li, Y., Li, G., Zeng, Z., Xiong, W., et al. (2019) · Journal of Cancer · doi:10.7150/jca.31166 · Cited by 106 · see citing works

Immunogenic stress and death of cancer cells: Contribution of antigenicity vs adjuvanticity to immunosurveillance

Bloy, N., Garcia, P., Laumont, C. M., Pitt, J. M., Sistigu, A., Stoll, G., Yamazaki, T., Bonneil, É., Buqué, A., Humeau, J. F., et al. (2017) · Immunological Reviews · doi:10.1111/imr.12582 · Cited by 103 · see citing works

Hypoxia-driven intratumor heterogeneity and immune evasion

Terry, S., Engelsen, A. S. T., Buart, S., El‐Sayed, W., Venkatesh, G. H., & Chouaı̈b, S. (2020) · Cancer Letters · doi:10.1016/j.canlet.2020.07.004 · Cited by 100 · see citing works

Biological causes of immunogenic cancer cell death (ICD) and anti-tumor therapy; Combination of Oncolytic virus-based immunotherapy and CAR T-cell therapy for ICD induction

Mardi, A., Shirokova, A. V., Mohammed, R. N., Keshavarz, A., Zekiy, A. O., Thangavelu, L. P., Mohammad, T. A. M., Marofi, F., Shomali, N., Zamani, A., et al. (2022) · Cancer Cell International · doi:10.1186/s12935-022-02585-z · Cited by 101 · see citing works

The Role of Decorin and Biglycan Signaling in Tumorigenesis

Diehl, V., Huber, L. S., Trebicka, J., Wygrecka, M., Iozzo, R. V., & Schaefer, L. (2021) · Frontiers in Oncology · doi:10.3389/fonc.2021.801801 · Cited by 97 · see citing works

A novel long noncoding RNA SP100-AS1 induces radioresistance of colorectal cancer via sponging miR-622 and stabilizing ATG3

Zhou, Y., Shao, Y., Hu, W., Zhang, J., Shi, Y., Kong, X., & Jiang, J. (2022) · Cell Death and Differentiation · doi:10.1038/s41418-022-01049-1 · Cited by 93 · see citing works

Pyridinium‐Substituted Tetraphenylethylenes Functionalized with Alkyl Chains as Autophagy Modulators for Cancer Therapy

Huang, Y., You, X., Wang, L., Zhang, G., Gui, S., Jin, Y., Zhao, R., & Zhang, D. (2020) · Angewandte Chemie International Edition · doi:10.1002/anie.202001906 · Cited by 93 · see citing works

Inhibiting autophagy flux and DNA repair of tumor cells to boost radiotherapy of orthotopic glioblastoma

Xu, Q., Zhang, H., Liu, H., Han, Y., Qiu, W., & Li, Z. (2021) · Biomaterials · doi:10.1016/j.biomaterials.2021.121287 · Cited by 91 · see citing works

Melatonin transport into mitochondria

Mayo, J. C., Sainz, R. M., González‐Menéndez, P., Hevia, D., & Cernuda‐Cernuda, R. (2017) · Cellular and Molecular Life Sciences · doi:10.1007/s00018-017-2616-8 · Cited by 90 · see citing works

Targeting Autophagy in the Tumor Microenvironment: New Challenges and Opportunities for Regulating Tumor Immunity

Janji, B., Berchem, G., & Chouaı̈b, S. (2018) · Frontiers in Immunology · doi:10.3389/fimmu.2018.00887 · Cited by 84 · see citing works

Transformable Nanoparticle‐Enabled Synergistic Elicitation and Promotion of Immunogenic Cell Death for Triple‐Negative Breast Cancer Immunotherapy

Xu, C., Yu, Y., Sun, Y., Kong, L., Yang, C., Hu, M. Y., Yang, T., Zhang, J., Hu, Q., & Zhang, Z. (2019) · Advanced Functional Materials · doi:10.1002/adfm.201905213 · Cited by 84 · see citing works

Circular CPM promotes chemoresistance of gastric cancer via activating PRKAA2‐mediated autophagy

Fang, L., Lv, J., Xuan, Z., Li, B., Li, Z., He, Z., Li, F., Xu, J., Wang, S., Xia, Y., et al. (2022) · Clinical and Translational Medicine · doi:10.1002/ctm2.708 · Cited by 83 · see citing works

Apigenin, by activating p53 and inhibiting STAT3, modulates the balance between pro-apoptotic and pro-survival pathways to induce PEL cell death

Granato, M., Montani, M. S. G., Santarelli, R., D’Orazi, G., Faggioni, A., & Cirone, M. (2017) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-017-0632-z · Cited by 83 · see citing works

HAMdb: a database of human autophagy modulators with specific pathway and disease information

Wang, N.-N., Dong, J., Zhang, L., Ouyang, D., Cheng, Y., Chen, A. F., Lu, A.-P., & Cao, D.-S. (2018) · Journal of Cheminformatics · doi:10.1186/s13321-018-0289-4 · Cited by 83 · see citing works

Autophagy modulation: a prudent approach in cancer treatment?

Bishop, E., & Bradshaw, T. D. (2018) · Cancer Chemotherapy and Pharmacology · doi:10.1007/s00280-018-3669-6 · Cited by 83 · see citing works

Enhancing tumor chemotherapy and overcoming drug resistance through autophagy-mediated intracellular dissolution of zinc oxide nanoparticles

Hu, Y. B., Zhang, H., Dong, L., Xu, M., Zhang, L., Ding, W., Zhang, J., Lin, J., Zhang, Y., Qiu, B., et al. (2019) · Nanoscale · doi:10.1039/c8nr08442d · Cited by 83 · see citing works

Targeting of cancer cell death mechanisms by curcumin: Implications to cancer therapy

Yu, C. H. A., Yang, B., & Najafi, M. (2021) · Basic & Clinical Pharmacology & Toxicology · doi:10.1111/bcpt.13648 · Cited by 78 · see citing works

Shikonin induces colorectal carcinoma cells apoptosis and autophagy by targeting galectin-1/JNK signaling axis

Zhang, N., Peng, F., Wang, Y., Li, Y., Wu, F., Wang, X., Cui, Y., Han, B., & He, G. (2019) · International Journal of Biological Sciences · doi:10.7150/ijbs.36955 · Cited by 76 · see citing works

3′-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells

Sun, Y., Huang, Y., Huang, F., Mei, W.-L., Liu, Q., Wang, C.-C., Lin, Y., Huang, C., Li, Y., Dai, H., et al. (2018) · Theranostics · doi:10.7150/thno.23304 · Cited by 75 · see citing works

Immune oncology, immune responsiveness and the theory of everything

Turan, T., Kannan, D., Patel, M. R., Barnes, J. M., Tanlimco, S. G., Lu, R. O., Halliwill, K. D., Kongpachith, S., Kline, D. E., Hendrickx, W., et al. (2018) · Journal for ImmunoTherapy of Cancer · doi:10.1186/s40425-018-0355-5 · Cited by 76 · see citing works

Autophagy in natural and therapy-driven anticancer immunosurveillance

Pietrocola, F., Pedro, J. M. B., Galluzzi, L., & Kroemer, G. (2017) · Autophagy · doi:10.1080/15548627.2017.1310356 · Cited by 72 · see citing works

Trial watch: immune checkpoint blockers for cancer therapy

Vanpouille-Box, C., Lhuillier, C., Bezu, L., Aranda, F., Yamazaki, T., Kepp, O., Fucikova, J., Spisek, R., Demaria, S., Formenti, S. C., et al. (2017) · OncoImmunology · doi:10.1080/2162402x.2017.1373237 · Cited by 73 · see citing works

Expression analysis of LC3B and p62 indicates intact activated autophagy is associated with an unfavorable prognosis in colon cancer

Niklaus, M., Adams, O. J., Berezowska, S., Zlobec, I., Graber, F., Slotta‐Huspenina, J., Nitsche, U., Rosenberg, R., Tschan, M. P., & Langer, R. (2017) · Oncotarget · doi:10.18632/oncotarget.17554 · Cited by 72 · see citing works

KLF5 downregulation desensitizes castration-resistant prostate cancer cells to docetaxel by increasing BECN1 expression and inducing cell autophagy

Jia, J., Zhang, H., Shi, Q., Yang, C., Ma, J., Jin, B., Wang, X., He, D., & Guo, P. (2019) · Theranostics · doi:10.7150/thno.33282 · Cited by 71 · see citing works

Astragalus polysaccharide enhanced antitumor effects of Apatinib in gastric cancer AGS cells by inhibiting AKT signalling pathway

Wu, J., Yu, J., Wang, J., Zhang, C., Shang, K., Yao, X., & Cao, B. (2018) · Biomedicine & Pharmacotherapy · doi:10.1016/j.biopha.2018.01.140 · Cited by 70 · see citing works

Interaction of Discoidin Domain Receptor 1 with a 14-3-3-Beclin-1-Akt1 Complex Modulates Glioblastoma Therapy Sensitivity

Vehlow, A., Klapproth, E., Jin, S., Hannen, R., Hauswald, M., Bartsch, J. W., Nimsky, C., Temme, A., Leitinger, B., & Cordes, N. (2019) · Cell Reports · doi:10.1016/j.celrep.2019.02.096 · Cited by 70 · see citing works

Potentiating prostate cancer immunotherapy with oncolytic viruses

Lee, P. C., & Gujar, S. A. (2018) · Nature Reviews Urology · doi:10.1038/nrurol.2018.10 · Cited by 69 · see citing works

Circulating Exosomal miR-141-3p and miR-375 in Metastatic Progression of Rectal Cancer

Meltzer, S., Bjørnetrø, T., Lyckander, L. G., Flatmark, K., Dueland, S., Samiappan, R., Johansen, C., Kalanxhi, E., Ree, A. H., & Redalen, K. R. (2019) · Translational Oncology · doi:10.1016/j.tranon.2019.04.014 · Cited by 68 · see citing works

LACTB Regulates PIK3R3 to Promote Autophagy and Inhibit EMT and Proliferation Through the PI3K/AKT/mTOR Signaling Pathway in Colorectal Cancer

Xu, W., Yu, M., Qin, J., Luo, Y., & Zhong, M. (2020) · Cancer Management and Research · doi:10.2147/cmar.s250661 · Cited by 68 · see citing works

Cell death pathologies: targeting death pathways and the immune system for cancer therapy

Pentimalli, F., Grelli, S., Daniele, N. D., Melino, G., & Amelio, I. (2018) · Genes and Immunity · doi:10.1038/s41435-018-0052-x · Cited by 67 · see citing works

Induction of immunogenic cell death in cancer cells by a photoactivated platinum( iv ) prodrug

Novohradský, V., Prachařová, J., Kašpárková, J., Imberti, C., Bridgewater, H. E., Sadler, P. J., & Brabec, V. (2020) · Inorganic Chemistry Frontiers · doi:10.1039/d0qi00991a · Cited by 67 · see citing works

Cell damage produced by magnetic fluid hyperthermia on microglial BV2 cells

Calatayud, M. P., Soler, E., Torres, T. E., González, E. C., Junquera, C., Ibarra, M. R., & Goya, G. F. (2017) · Scientific Reports · doi:10.1038/s41598-017-09059-7 · Cited by 66 · see citing works

Autophagy manipulation as a strategy for efficient anticancer therapies: possible consequences

Cirone, M., Montani, M. S. G., Granato, M., Garufi, A., Faggioni, A., & D’Orazi, G. (2019) · Journal of Experimental & Clinical Cancer Research · doi:10.1186/s13046-019-1275-z · Cited by 64 · see citing works

Therapeutic modulation of autophagy: which disease comes first?

Maiuri, M. C., & Kroemer, G. (2019) · Cell Death and Differentiation · doi:10.1038/s41418-019-0290-0 · Cited by 63 · see citing works

Molecular Insights Into Therapeutic Potential of Autophagy Modulation by Natural Products for Cancer Stem Cells

Rahman, M. A., Saha, S. K., Rahman, M. S., Uddin, M. J., Uddin, M. S., Pang, M., Rhim, H., & Cho, S. (2020) · Frontiers in Cell and Developmental Biology · doi:10.3389/fcell.2020.00283 · Cited by 63 · see citing works

Gold nanoparticles impair autophagy flux through shape-dependent endocytosis and lysosomal dysfunction

Zhou, H., Gong, X., Lin, H., Chen, H., Huang, D., Li, D., Shan, H., & Gao, J. (2018) · Journal of Materials Chemistry B · doi:10.1039/c8tb02390e · Cited by 63 · see citing works

The use of African medicinal plants in cancer management

Gaobotse, G., Venkataraman, S., Brown, P. D., Masisi, K., Kwape, T. E., Nkwe, D. O., Rantong, G., & Makhzoum, A. B. (2023) · Frontiers in Pharmacology · doi:10.3389/fphar.2023.1122388 · Cited by 62 · see citing works

Engineering mitochondrial uncoupler synergistic photodynamic nanoplatform to harness immunostimulatory pro-death autophagy/mitophagy

Sun, Q., Yang, J., Shen, W. H., Lu, H., Hou, X., Liu, Y., Xu, Y., Wu, Q., Xuan, Z., Yang, Y., et al. (2022) · Biomaterials · doi:10.1016/j.biomaterials.2022.121796 · Cited by 61 · see citing works

The role of radiation induced oxidative stress as a regulator of radio-adaptive responses

Sisakht, M., Darabian, M., Mahmoodzadeh, A., Bazı, A., Shafiee, S. M., Mokarram, P., & Khoshdel, Z. (2020) · International Journal of Radiation Biology · doi:10.1080/09553002.2020.1721597 · Cited by 60 · see citing works

Molecular determinants of immunogenic cell death elicited by radiation therapy

Galassi, C., Klapp, V., Yamazaki, T., & Galluzzi, L. (2023) · Immunological Reviews · doi:10.1111/imr.13271 · Cited by 63 · see citing works

Trial Watch: Immunostimulation with recombinant cytokines for cancer therapy

García-Martínez, E., Smith, M. M., Buqué, A., Aranda, F., de la Peña, F. A., Rubio, A. I., Cánovas, M. S., Conesa, M. A. V., Fucikova, J. P., Špíšek, R., et al. (2018) · OncoImmunology · doi:10.1080/2162402x.2018.1433982 · Cited by 56 · see citing works

Redox-responsive nanoassembly restrained myeloid-derived suppressor cells recruitment through autophagy-involved lactate dehydrogenase A silencing for enhanced cancer immunochemotherapy

Xia, C., Li, M., Ran, G., Wang, X., Lu, Z., Li, T., Tang, X., Zhang, Z., & He, Q. (2021) · Journal of Controlled Release · doi:10.1016/j.jconrel.2021.05.034 · Cited by 55 · see citing works

TRPM2-AS promotes cancer cell proliferation through control of TAF15

Li, P., Li, Y., Jin, L., Li, J., & Xu, A. (2019) · The International Journal of Biochemistry & Cell Biology · doi:10.1016/j.biocel.2019.105683 · Cited by 54 · see citing works

Linc-RA1 inhibits autophagy and promotes radioresistance by preventing H2Bub1/USP44 combination in glioma cells

Zheng, J., Wang, B., Zheng, R., Zhang, J., Huang, C., Zheng, R., Huang, Z., Qiu, W., Liu, M., Yang, K., et al. (2020) · Cell Death and Disease · doi:10.1038/s41419-020-02977-x · Cited by 54 · see citing works

Chloroquine supplementation increases the cytotoxic effect of curcumin against Her2/neu overexpressing breast cancer cells in vitro and in vivo in nude mice while counteracts it in immune competent mice

Masuelli, L., Granato, M., Benvenuto, M., Mattera, R., Bernardini, R., Mattei, M., d’Amati, G., D’Orazi, G., Faggioni, A., Bei, R., et al. (2017) · OncoImmunology · doi:10.1080/2162402x.2017.1356151 · Cited by 53 · see citing works

Epigenetic targeting of autophagy for cancer prevention and treatment by natural compounds

Vidoni, C., Ferraresi, A., Secomandi, E., Vallino, L., Dhanasekaran, D. N., & Isidoro, C. (2019) · Seminars in Cancer Biology · doi:10.1016/j.semcancer.2019.04.006 · Cited by 54 · see citing works

Novel and Alternative Targets Against Breast Cancer Stemness to Combat Chemoresistance

Sridharan, S., Howard, C. M., Tilley, A. M. C., Subramaniyan, B., Tiwari, A. K., Ruch, R. J., & Raman, D. (2019) · Frontiers in Oncology · doi:10.3389/fonc.2019.01003 · Cited by 53 · see citing works

Autophagy blockade synergistically enhances nanosonosensitizer-enabled sonodynamic cancer nanotherapeutics

Zhou, L., Huo, M., Qian, X., Ding, L., Yu, L., Feng, W., Cui, X., & Chen, Y. (2021) · Journal of Nanobiotechnology · doi:10.1186/s12951-021-00855-y · Cited by 53 · see citing works

The interplay between autophagy and cGAS-STING signaling and its implications for cancer

Schmid, M., Fischer, P., Engl, M., Widder, J., Gruber, S., & Slade, D. (2024) · Frontiers in Immunology · doi:10.3389/fimmu.2024.1356369 · Cited by 55 · see citing works

Autophagy inhibition radiosensitizes in vitro, yet reduces radioresponses in vivo due to deficient immunogenic signalling

Ko, A., Kanehisa, A., Martins, I., Senovilla, L., Chargari, C., Dugué, D., Mariño, G., Kepp, O., Michaud, M., Perfettini, J., et al. (2013) · Cell Death and Differentiation · doi:10.1038/cdd.2013.124 · Cited by 205 · see citing works

Autophagy in natural and therapy-driven anticancer immunosurveillance

Pietrocola, F., Pedro, J. M. B., Galluzzi, L., & Kroemer, G. (2017) · Autophagy · doi:10.1080/15548627.2017.1310356 · Cited by 72 · see citing works

Role of Autophagy in Cancer Therapy

Ma, Y. (2016) · Elsevier eBooks · doi:10.1016/b978-0-12-802937-4.00013-2

Abstract 2262: Contribution of autophagy in anticancer immune response induced by chemotherapy

Sukkurwala, A. Q., Michaud, M., Martins, I., & Kroemer, G. (2012) · Cancer Research · doi:10.1158/1538-7445.am2012-2262

R(h)oad to antitumour therapy

Conceicao, V. N. D., Mishra, B. B., & Singh, B. B. (2022) · Clinical and Translational Discovery · doi:10.1002/ctd2.160