Gage, Fred H.

Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells

Topol, A., Zhu, S., Hartley, B. J., English, J., Hauberg, M. E., Tran, N., Rittenhouse, C. A., Simone, A., Ruderfer, D. M., Johnson, J., et al. (2016) · Cell Reports

MicroRNA in disease regulationSchizophrenia research and treatment

Cited by 122

Incorporation of a nucleoside analog maps genome repair sites in postmitotic human neurons

Reid, D. A., Reed, P. J., Schlachetzki, J. C. M., Nitulescu, I. I., Chou, G., Tsui, E. C., Jones, J. R., Chandran, S., Lu, A. T., McClain, C. A., et al. (2021) · Science

DNA Repair MechanismsDNA and Nucleic Acid Chemistry

Cited by 121

Modeling psychiatric disorders at the cellular and network levels

Brennand, K. J., Simone, A., Tran, N., & Gage, F. H. (2012) · Molecular Psychiatry

Pluripotent Stem Cells ResearchNeuroscience and Neuropharmacology Research

Cited by 119

Mitochondrial aging defects emerge in directly reprogrammed human neurons due to their metabolic profile

Kim, Y., Zheng, X., Ansari, Z., Bunnell, M. C., Herdy, J. R., Traxler, L., Lee, H., Paquola, A. C. M., Blithikioti, C., Ku, M., et al. (2018) · Cell Reports

Mitochondrial Function and PathologyPluripotent Stem Cells Research

Cited by 117

Adult neurogenesis: bridging the gap between mice and humans

Jessberger, S., & Gage, F. H. (2014) · Trends in Cell Biology

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 116

Increased Neural Progenitor Proliferation in a hiPSC Model of Autism Induces Replication Stress-Associated Genome Instability

Wang, M., Wei, P.-C., Lim, C. K., Gallina, I. S., Marshall, S., Marchetto, M. C., Alt, F. W., & Gage, F. H. (2020) · Cell Stem Cell

Autism Spectrum Disorder ResearchGenetics and Neurodevelopmental Disorders

Cited by 105

An Epilepsy-Associated KCNT1 Mutation Enhances Excitability of Human iPSC-Derived Neurons by Increasing Slack KNa Currents

Quraishi, I. H., Stern, S., Mangan, K. P., Zhang, Y., Ali, S. R., Mercier, M. R., Marchetto, M. C., McLachlan, M. J., Jones, E. M., Gage, F. H., et al. (2019) · The Journal of Neuroscience

Ion channel regulation and functionEpilepsy research and treatment

Cited by 103

Brain-derived neurotrophic factor interacts with adult-born immature cells in the dentate gyrus during consolidation of overlapping memories.

Bekinschtein, P., Kent, B. A., Oomen, C. A., Clemenson, G. D., Gage, F. H., Saksida, L. M., & Bussey, T. J. (2014) · Hippocampus

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 94

Temporally selective contextual encoding in the dentate gyrus of the hippocampus

Rangel, L. M., Alexander, A. S., Aimone, J. B., Wiles, J., Gage, F. H., Chiba, A. A., & Quinn, L. K. (2014) · Nature Communications

Memory and Neural MechanismsNeurogenesis and neuroplasticity mechanisms

Cited by 91

AAV ablates neurogenesis in the adult murine hippocampus

Johnston, S., Parylak, S. L., Kim, S., Mac, N., Lim, C., Gallina, I., Bloyd, C., Newberry, A., Saavedra, C. D., Novak, O., et al. (2021) · eLife

Virus-based gene therapy researchNeurogenesis and neuroplasticity mechanisms

Cited by 87

Stem-cell-associated structural and functional plasticity in the aging hippocampus.

Jessberger, S., & Gage, F. H. (2008) · Psychology and Aging

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 85

Brain-derived neurotrophic factor-transduced fibroblasts: Production of BDNF and effects of grafting to the adult rat brain

Lucidi‐Phillipi, C. A., Gage, F. H., Shults, C. W., Jones, K. R., Reichardt, L. F., & Kang, U. J. (1995) · Journal of Comparative Neurology

Nerve injury and regenerationParkinson's Disease Mechanisms and Treatments

Cited by 72

An exploratory study of combination buspirone and melatonin SR in Major Depressive Disorder (MDD): A possible role for neurogenesis in drug discovery

Fava, M., Targum, S. D., Nierenberg, A. A., Bleicher, L. S., Carter, T. A., Wedel, P. C., Hen, R., Gage, F. H., & Barlow, C. (2012) · Journal of Psychiatric Research

Treatment of Major DepressionNeurotransmitter Receptor Influence on Behavior

Cited by 67

Dependence of hippocampal function on ERRγ-regulated mitochondrial metabolism

Pei, L., Mu, Y., Leblanc, M., Alaynick, W., Barish, G. D., Pankratz, M., Tseng, T. W., Kaufman, S., Liddle, C., Yu, R. T., et al. (2015) · Cell Metabolism

Neuroscience and Neuropharmacology ResearchMitochondrial Function and Pathology

Cited by 65

Cytoplasmic synthesis of endogenous Alu complementary DNA via reverse transcription and implications in age-related macular degeneration

Fukuda, S., Varshney, A., Fowler, B. J., Wang, S.-B., Narendran, S., Ambati, K., Yasuma, T., Magagnoli, J., Leung, H., Hirahara, S., et al. (2021) · Proceedings of the National Academy of Sciences

Chromosomal and Genetic VariationsRetinal Diseases and Treatments

Cited by 65

Chemical modulation of transcriptionally enriched signaling pathways to optimize the conversion of fibroblasts into neurons

Herdy, J., Schafer, S., Kim, Y., Ansari, Z., Zangwill, D., Ku, M., Paquola, A., Lee, H., Mertens, J., & Gage, F. H. (2019) · eLife

Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 64

Mechanisms Underlying the Hyperexcitability of CA3 and Dentate Gyrus Hippocampal Neurons Derived From Patients With Bipolar Disorder

Stern, S., Sarkar, A., Stern, T., Mei, A., Mendes, A. P. D., Stern, Y., Goldberg, G., Galor, D., Nguyen, T., Randolph-Moore, L., et al. (2020) · Biological Psychiatry

Bipolar Disorder and TreatmentNeuroscience and Neuropharmacology Research

Cited by 59

Pre-existing astrocytes form functional perisynaptic processes on neurons generated in the adult hippocampus

Krzisch, M., Temprana, S. G., Mongiat, L. A., Armida, J., Schmutz, V., Virtanen, M. A., Kocher-Braissant, J., Kraftsik, R., Vutskits, L., Conzelmann, K.-K., et al. (2015) · Brain Structure and Function

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 57

Training the next generation of biomedical investigators in glycosciences

Agre, P., Bertozzi, C., Bissell, M., Campbell, K. P., Cummings, R. D., Desai, U. R., Estes, M., Flotte, T., Fogleman, G., Gage, F., et al. (2016) · Journal of Clinical Investigation

Glycosylation and Glycoproteins ResearchHealth and Medical Research Impacts

Cited by 34

BrainImageR: spatiotemporal gene set analysis referencing the human brain

Linker, S. B., Hsu, J. Y., Pfaff, A., Amatya, D., Ko, S.-M., Voter, S., Wong, Q., & Gage, F. H. (2019) · Bioinformatics

Bioinformatics and Genomic NetworksSingle-cell and spatial transcriptomics

Cited by 7