Gage, Fred H.

Neurogenesis in the adult hippocampus

Kempermann, G., Song, H., & Gage, F. H. (2015) · Cold Spring Harbor Perspectives in Biology

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 1,072

Adult hippocampal neurogenesis and its role in Alzheimer’s disease

Mu, Y., & Gage, F. H. (2011) · Molecular Neurodegeneration

Neurogenesis and neuroplasticity mechanismsAlzheimer's disease research and treatments

Cited by 1,021

Adult brain neurogenesis and psychiatry: a novel theory of depression

Jacobs, B. L., van Praag, H., & Gage, F. H. (2000) · Molecular Psychiatry

Neurogenesis and neuroplasticity mechanismsStress Responses and Cortisol

Cited by 964

A Nurr1/CoREST Pathway in Microglia and Astrocytes Protects Dopaminergic Neurons from Inflammation-Induced Death

Saijo, K., Winner, B., Carson, C. T., Collier, J. G., Boyer, L., Rosenfeld, M. G., Gage, F. H., & Glass, C. K. (2009) · Cell

Nuclear Receptors and SignalingNeuroinflammation and Neurodegeneration Mechanisms

Cited by 957

Stem and progenitor cells: origins, phenotypes, lineage commitments, and transdifferentiations

Weissman, I. L., Anderson, D. J., & Gage, F. (2001) · Annual Review of Cell and Developmental Biology

Hematopoietic Stem Cell TransplantationMesenchymal stem cell research

Cited by 948

Somatic mosaicism in neuronal precursor cells mediated by L1 retrotransposition

Muotri, A. R., Chu, V. T., Marchetto, M. C. N., Deng, W., Moran, J. V., & Gage, F. H. (2005) · Nature

Chromosomal and Genetic VariationsNeurogenesis and neuroplasticity mechanisms

Cited by 942

Neuroplasticity in old age: Sustained fivefold induction of hippocampal neurogenesis by long‐term environmental enrichment

Kempermann, G., Gast, D., & Gage, F. H. (2002) · Annals of Neurology

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 889

Retrograde Viral Delivery of IGF-1 Prolongs Survival in a Mouse ALS Model

Kaspar, B. K., Lladó, J., Sherkat, N., Rothstein, J. D., & Gage, F. H. (2003) · Science

Amyotrophic Lateral Sclerosis ResearchNeurogenetic and Muscular Disorders Research

Cited by 872

Effects of voluntary exercise on synaptic plasticity and gene expression in the dentate gyrus of adult male Sprague-Dawley rats in vivo

Farmer, J., Zhao, X., van Praag, H., Wodtke, K., Gage, F. H., & Christie, B. R. (2004) · Neuroscience

Neuroscience and Neuropharmacology ResearchNeurogenesis and neuroplasticity mechanisms

Cited by 836

L1 retrotransposition in human neural progenitor cells

Coufal, N. G., Garcia-Perez, J. L., Peng, G. E., Yeo, G. W., Mu, Y., Lovci, M. T., Morell, M., O’Shea, K. S., Moran, J. V., & Gage, F. H. (2009) · Nature

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 814

Enriched environment and physical activity stimulate hippocampal but not olfactory bulb neurogenesis

Brown, J., Cooper‐Kuhn, C. M., Kempermann, G., Van Praag, H., Winkler, J., Gage, F. H., & Kuhn, H. G. (2003) · European Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 809

Combined adult neurogenesis and BDNF mimic exercise effects on cognition in an Alzheimer’s mouse model

Choi, S. H., Bylykbashi, E., Chatila, Z. K., Lee, S. W., Pulli, B., Clemenson, G. D., Kim, E., Rompala, A., Oram, M. K., Asselin, C., et al. (2018) · Science

Neurogenesis and neuroplasticity mechanismsAlzheimer's disease research and treatments

Cited by 802

Human Adult Neurogenesis: Evidence and Remaining Questions

Kempermann, G., Gage, F. H., Aigner, L., Song, H., Curtis, M. A., Thuret, S., Kuhn, H. G., Jessberger, S., Frankland, P. W., Cameron, H. A., et al. (2018) · Cell Stem Cell

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 790

Proliferation and Differentiation of Progenitor Cells Throughout the Intact Adult Rat Spinal Cord

Horner, P. J., Power, A. E., Kempermann, G., Kuhn, H. G., Palmer, T. D., Winkler, J., Thal, L. J., & Gage, F. H. (2000) · The Journal of Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroinflammation and Neurodegeneration Mechanisms

Cited by 777

Directly Reprogrammed Human Neurons Retain Aging-Associated Transcriptomic Signatures and Reveal Age-Related Nucleocytoplasmic Defects.

Mertens, J., Paquola, A. C. M., Ku, M., Hatch, E., Böhnke, L., Ladjevardi, S., McGrath, S., Campbell, B., Lee, H., Herdy, J. R., et al. (2015) · Cell Stem Cell

Pluripotent Stem Cells ResearchGenetics, Aging, and Longevity in Model Organisms

Cited by 765

Neurons born in the adult dentate gyrus form functional synapses with target cells

Toni, N., Laplagne, D. A., Zhao, C., Lombardi, G., Ribak, C. E., Gage, F. H., & Schinder, A. F. (2008) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsNeuroscience and Neuropharmacology Research

Cited by 741

The role of adult hippocampal neurogenesis in brain health and disease

Toda, T., Parylak, S. L., Linker, S. B., & Gage, F. H. (2019) · Molecular Psychiatry

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 719

Brain cell type–specific enhancer–promoter interactome maps and disease - risk association

Nott, A., Holtman, I. R., Coufal, N. G., Schlachetzki, J. C. M., Yu, M., Hu, R., Han, C. Z., Pena, M., Xiao, J., Wu, Y., et al. (2019) · Science

Genomics and Chromatin DynamicsGenetic Associations and Epidemiology

Cited by 699

Metabolic reprogramming during neuronal differentiation from aerobic glycolysis to neuronal oxidative phosphorylation

Zheng, X., Boyer, L., Jin, M., Mertens, J., Kim, Y., Ma, L., Ma, L., Hamm, M., Gage, F. H., & Hunter, T. (2016) · eLife

Neurogenesis and neuroplasticity mechanismsCancer, Hypoxia, and Metabolism

Cited by 671

Resolving new memories: a critical look at the dentate gyrus, adult neurogenesis, and pattern separation

Aimone, J. B., Deng, W., & Gage, F. H. (2011) · Neuron

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 663

Dentate gyrus-specific knockdown of adult neurogenesis impairs spatial and object recognition memory in adult rats

Jessberger, S., Clark, R. E., Broadbent, N. J., Clemenson, G. D., Consiglio, A., Lie, D. C., Squire, L. R., & Gage, F. H. (2009) · Learning & Memory

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 654

Wnt-mediated activation of NeuroD1 and retro-elements during adult neurogenesis

Kuwabara, T., Hsieh, J., Muotri, A., Yeo, G., Warashina, M., Lie, D. C., Moore, L., Nakashima, K., Asashima, M., & Gage, F. H. (2009) · Nature Neuroscience

Neurogenesis and neuroplasticity mechanismsWnt/β-catenin signaling in development and cancer

Cited by 648

Regulation and function of adult neurogenesis: from genes to cognition.

Aimone, J. B., Li, Y., Lee, S. W., Clemenson, G. D., Deng, W., & Gage, F. H. (2014) · Physiological Reviews

Neurogenesis and neuroplasticity mechanismsMemory and Neural Mechanisms

Cited by 635

L1 retrotransposition in neurons is modulated by MeCP2

Muotri, A. R., Marchetto, M. C. N., Coufal, N. G., Oefner, R., Yeo, G., Nakashima, K., & Gage, F. H. (2010) · Nature

Genetics and Neurodevelopmental DisordersChromosomal and Genetic Variations

Cited by 626