Green, Douglas R.

Many players in BCL-2 family affairs

Moldoveanu, T., Follis, A. V., Kriwacki, R. W., & Green, D. R. (2014) · Trends in Biochemical Sciences

Cell death mechanisms and regulationMitochondrial Function and Pathology

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Dynamic programming of CD8+ T lymphocyte responses

van Stipdonk, M. J. B., Hardenberg, G., Bijker, M. S., Lemmens, E. E., Droin, N. M., Green, D. R., & Schoenberger, S. P. (2003) · Nature Immunology

T-cell and B-cell ImmunologyImmunotherapy and Immune Responses

Cited by 401

Receptor interacting protein kinase 2–mediated mitophagy regulates inflammasome activation during virus infection

Lupfer, C., Thomas, P. G., Anand, P. K., Vogel, P., Milasta, S., Martinez, J., Huang, G., Green, M., Kundu, M., Chi, H., et al. (2013) · Nature Immunology

Inflammasome and immune disordersAutophagy in Disease and Therapy

Cited by 384

CD95-Induced Apoptosis of Lymphocytes in an Immune Privileged Site Induces Immunological Tolerance

Griffith, T. S., Yu, X., Herndon, J. M., Green, D. R., & Ferguson, T. A. (1996) · Immunity

T-cell and B-cell ImmunologyCell death mechanisms and regulation

Cited by 382

RETRACTED ARTICLE: Noncanonical autophagy inhibits the autoinflammatory, lupus-like response to dying cells

Martinez, J., Cunha, L. D., Park, S., Yang, M., Lu, Q., Orchard, R., Li, Q.-Z., Yan, M., Janke, L., Guy, C., et al. (2016) · Nature

Systemic Lupus Erythematosus ResearchAutophagy in Disease and Therapy

Cited by 381

Die another way – non-apoptotic mechanisms of cell death

Tait, S. W. G., Ichim, G., & Green, D. R. (2014) · Journal of Cell Science

Cell death mechanisms and regulationInflammasome and immune disorders

Cited by 366

Mitochondrial dysfunction in ataxia-telangiectasia

Valentin-Vega, Y. A., MacLean, K. H., Tait-Mulder, J., Milasta, S., Steeves, M., Dorsey, F. C., Cleveland, J. L., Green, D. R., & Kastan, M. B. (2012) · Blood

Mitochondrial Function and PathologyAutophagy in Disease and Therapy

Cited by 365

Noncanonical Autophagy Is Required for Type I Interferon Secretion in Response to DNA-Immune Complexes

Henault, J., Martinez, J., Riggs, J. M., Tian, J., Mehta, P., Clarke, L., Sasai, M., Latz, E., Brinkmann, M. M., Iwasaki, A., et al. (2012) · Immunity

Immune Response and InflammationAutophagy in Disease and Therapy

Cited by 348

Noncanonical autophagy promotes the visual cycle

Kim, J.-Y., Zhao, H., Martinez, J., Doggett, T. A., Kolesnikov, A. V., Tang, P. H., Ablonczy, Z., Chan, C.-C., Zhou, Z., Green, D. R., et al. (2013) · Cell

Autophagy in Disease and TherapyRetinal Development and Disorders

Cited by 347

LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance

Cunha, L. D., Yang, M., Carter, R., Guy, C., Harris, L., Crawford, J. C., Quarato, G., Boada-Romero, E., Kalkavan, H., Johnson, M. D. L., et al. (2018) · Cell

Autophagy in Disease and TherapyPhagocytosis and Immune Regulation

Cited by 334

Survival Function of the FADD-CASPASE-8-cFLIPL Complex

Dillon, C. P., Oberst, A., Weinlich, R., Janke, L. J., Kang, T.-B., Ben-Moshe, T., Mak, T. W., Wallach, D., & Green, D. R. (2012) · Cell Reports

Cell death mechanisms and regulationInflammasome and immune disorders

Cited by 331

The clearance of dying cells: table for two

Green, D. R., Oguin, T. H., & Martinez, J. (2016) · Cell Death & Differentiation

Phagocytosis and Immune RegulationAutophagy in Disease and Therapy

Cited by 314

The Autophagy Machinery Controls Cell Death Switching between Apoptosis and Necroptosis

Goodall, M. L., Fitzwalter, B. E., Zahedi, S., Wu, M., Rodriguez, D., Mulcahy-Levy, J. M., Green, D. R., Morgan, M., Cramer, S. D., & Thorburn, A. (2016) · Developmental Cell

Cell death mechanisms and regulationAutophagy in Disease and Therapy

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Widespread Mitochondrial Depletion via Mitophagy Does Not Compromise Necroptosis

Tait, S. W. G., Oberst, A., Quarato, G., Milasta, S., Haller, M., Wang, R., Karvela, M., Ichim, G., Yatim, N., Albert, M. L., et al. (2013) · Cell Reports

Cell death mechanisms and regulationMitochondrial Function and Pathology

Cited by 303

RIPK1 both positively and negatively regulates RIPK3 oligomerization and necroptosis

Orozco, S., Yatim, N., Werner, M. R., Tran, H., Gunja, S. Y., Tait, S. W., Albert, M. L., Green, D. R., & Oberst, A. (2014) · Cell Death & Differentiation

Cell death mechanisms and regulationNF-κB Signaling Pathways

Cited by 294

LC3-Associated Phagocytosis and Inflammation

Heckmann, B. L., Boada-Romero, E., Cunha, L. D., Magne, J., & Green, D. R. (2017) · Journal of Molecular Biology

Autophagy in Disease and TherapyPhagocytosis and Immune Regulation

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BOK Is a Non-canonical BCL-2 Family Effector of Apoptosis Regulated by ER-Associated Degradation

Llambi, F., Wang, Y.-M., Victor, B., Yang, M., Schneider, D. M., Gingras, S., Parsons, M. J., Zheng, J. H., Brown, S. A., Pelletier, S., et al. (2016) · Cell

Cell death mechanisms and regulationUbiquitin and proteasome pathways

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The Pseudokinase MLKL and the Kinase RIPK3 Have Distinct Roles in Autoimmune Disease Caused by Loss of Death-Receptor-Induced Apoptosis

Alvarez-Diaz, S., Dillon, C. P., Lalaoui, N., Tanzer, M. C., Rodriguez, D. A., Lin, A., Lebois, M., Hakem, R., Josefsson, E. C., O’Reilly, L. A., et al. (2016) · Immunity

Cell death mechanisms and regulationNF-κB Signaling Pathways

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Inducible Dimerization and Inducible Cleavage Reveal a Requirement for Both Processes in Caspase-8 Activation

Oberst, A., Pop, C., Tremblay, A. G., Blais, V., Denault, J.-B., Salvesen, G. S., & Green, D. R. (2010) · Journal of Biological Chemistry

Cell death mechanisms and regulationInflammasome and immune disorders

Cited by 214

Regional analysis of p53 mutations in rheumatoid arthritis synovium

Yamanishi, Y., Boyle, D. L., Rosengren, S., Green, D. R., Zvaifler, N. J., & Firestein, G. S. (2002) · Proceedings of the National Academy of Sciences

Rheumatoid Arthritis Research and TherapiesCancer-related Molecular Pathways

Cited by 214

Protective Roles for Caspase-8 and cFLIP in Adult Homeostasis

Weinlich, R., Oberst, A., Dillon, C. P., Janke, L. J., Milasta, S., Lukens, J. R., Rodriguez, D. A., Gurung, P., Savage, C., Kanneganti, T. D., et al. (2013) · Cell Reports

Cell death mechanisms and regulationNF-κB Signaling Pathways

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Toll-like receptor signaling in the lysosomal pathways

Sanjuan, M. A., Milasta, S., & Green, D. R. (2009) · Immunological Reviews

Immune Response and InflammationAutophagy in Disease and Therapy

Cited by 137

Noncanonical function of an autophagy protein prevents spontaneous Alzheimer’s disease

Heckmann, B. L., Teubner, B. J. W., Boada-Romero, E., Tummers, B., Guy, C., Fitzgerald, P., Mayer, U., Carding, S., Zakharenko, S. S., Wileman, T., et al. (2020) · Science Advances

Alzheimer's disease research and treatmentsAutophagy in Disease and Therapy

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Systems analysis of BCL2 protein family interactions establishes a model to predict responses to chemotherapy

Lindner, A. U., Concannon, C. G., Boukes, G. J., Cannon, M. D., Llambi, F., Ryan, D., Boland, K., Kehoe, J., McNamara, D. A., Murray, F., et al. (2013) · Cancer Research

Cell death mechanisms and regulationCancer-related Molecular Pathways

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