Lammers, Twan

Drug targeting to tumors: Principles, pitfalls and (pre-) clinical progress

Lammers, T., Kiessling, F., Hennink, W. E., & Storm, G. (2012) · Journal of Controlled Release

Nanoparticle-Based Drug DeliveryNanoplatforms for cancer theranostics

Cited by 1,324

Tumor targeting via EPR: Strategies to enhance patient responses

Golombek, S. K., May, J.-N., Theek, B., Appold, L., Drude, N., Kiessling, F., & Lammers, T. (2018) · Advanced Drug Delivery Reviews

Nanoparticle-Based Drug DeliveryNanoplatforms for cancer theranostics

Cited by 1,262

Iron oxide nanoparticles: Diagnostic, therapeutic and theranostic applications

Dadfar, S. M., Roemhild, K., Drude, N. I., von Stillfried, S., Knüchel, R., Kiessling, F., & Lammers, T. (2019) · Advanced Drug Delivery Reviews

Characterization and Applications of Magnetic NanoparticlesNanoparticle-Based Drug Delivery

Cited by 1,181

The EPR effect and beyond: Strategies to improve tumor targeting and cancer nanomedicine treatment efficacy

Shi, Y., van der Meel, R., Chen, X., & Lammers, T. (2020) · Theranostics

Nanoparticle-Based Drug DeliveryNanoplatforms for cancer theranostics

Cited by 868

Integrating Artificial Intelligence and Nanotechnology for Precision Cancer Medicine

Adir, O., Poley, M., Chen, G., Froim, S., Krinsky, N., Shklover, J., Shainsky‐Roitman, J., Lammers, T., & Schroeder, A. (2020) · Advanced Materials

Nanoplatforms for cancer theranosticsNanoparticle-Based Drug Delivery

Cited by 496

Nanotheranostics and image-guided drug delivery: current concepts and future directions

Lammers, T., Kiessling, F., Hennink, W. E., & Storm, G. (2010) · Molecular Pharmaceutics

Nanoparticle-Based Drug DeliveryNanoplatforms for cancer theranostics

Cited by 397

Targeting iron metabolism in drug discovery and delivery

Crielaard, B. J., Lammers, T., & Rivella, S. (2017) · Nature Reviews Drug Discovery

Iron Metabolism and DisordersFerroptosis and cancer prognosis

Cited by 352

CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis

Ehling, J., Bartneck, M., Wei, X., Gremse, F., Fech, V., Möckel, D., Baeck, C., Hittatiya, K., Eulberg, D., Luedde, T., et al. (2014) · Gut

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 273

Pharmacological and physical vessel modulation strategies to improve EPR-mediated drug targeting to tumors

Ojha, T., Pathak, V., Shi, Y., Hennink, W. E., Moonen, C. T. W., Storm, G., Kiessling, F., & Lammers, T. (2017) · Advanced Drug Delivery Reviews

Nanoparticle-Based Drug DeliveryAngiogenesis and VEGF in Cancer

Cited by 260

Metallodrugs in cancer nanomedicine

Peña, Q., Wang, A., Zaremba, O., Shi, Y., Scheeren, H. W., Metselaar, J. M., Kiessling, F., Pallares, R. M., Wuttke, S., & Lammers, T. (2022) · Chemical Society Reviews

Metal complexes synthesis and propertiesNanoparticle-Based Drug Delivery

Cited by 259

Nanoparticles for Imaging: top or Flop?

Kiessling, F., Mertens, M. E., Grimm, J., & Lammers, T. (2014) · Radiology

Nanoparticle-Based Drug DeliveryCharacterization and Applications of Magnetic Nanoparticles

Cited by 228

Superparamagnetic iron oxide nanoparticles encapsulated in biodegradable thermosensitive polymeric micelles: toward a targeted nanomedicine suitable for image-guided drug delivery

Talelli, M., Rijcken, C. J. F., Lammers, T., Seevinck, P. R., Storm, G., van Nostrum, C. F., & Hennink, W. E. (2009) · Langmuir

Nanoparticle-Based Drug DeliveryCharacterization and Applications of Magnetic Nanoparticles

Cited by 210

Enhancing tumor penetration of nanomedicines

Sun, Q., Ojha, T., Kiessling, F., Lammers, T., & Shi, Y. (2017) · Biomacromolecules

Nanoparticle-Based Drug DeliveryNanoplatforms for cancer theranostics

Cited by 198

Physico-chemical strategies to enhance stability and drug retention of polymeric micelles for tumor-targeted drug delivery

Shi, Y., Lammers, T., Storm, G., & Hennink, W. E. (2017) · Macromolecular Bioscience

Nanoparticle-Based Drug DeliveryDendrimers and Hyperbranched Polymers

Cited by 174

Theranostic USPIO‐Loaded Microbubbles for Mediating and Monitoring Blood‐Brain Barrier Permeation

Lammers, T., Koczera, P., Fokong, S., Gremse, F., Ehling, J., Vogt, M., Pich, A., Storm, G., van Zandvoort, M., & Kiessling, F. (2015) · Advanced Functional Materials

Ultrasound and Hyperthermia ApplicationsBarrier Structure and Function Studies

Cited by 156

Fluorescent cell-traceable dexamethasone-loaded liposomes for the treatment of inflammatory liver diseases

Bartneck, M., Scheyda, K. M., Warzecha, K. T., Rizzo, L. Y., Hittatiya, K., Luedde, T., Storm, G., Trautwein, C., Lammers, T., & Tacke, F. (2015) · Biomaterials

Nanoparticle-Based Drug DeliveryLiver physiology and pathology

Cited by 141

Effect of radiotherapy and hyperthermia on the tumor accumulation of HPMA copolymer-based drug delivery systems

Lammers, T., Peschke, P., Kühnlein, R., Subr, V., Ulbrich, K., Debus, J., Huber, P., Hennink, W., & Storm, G. (2007) · Journal of Controlled Release

Nanoparticle-Based Drug DeliveryUltrasound and Hyperthermia Applications

Cited by 124

Histidine‐rich glycoprotein promotes macrophage activation and inflammation in chronic liver disease

Bartneck, M., Fech, V., Ehling, J., Govaere, O., Warzecha, K. T., Hittatiya, K., Vucur, M., Gautheron, J., Luedde, T., Trautwein, C., et al. (2016) · Hepatology

Liver physiology and pathologyImmune cells in cancer

Cited by 101

Pharmacological intervention in hepatic stellate cell activation and hepatic fibrosis

Schon, H.-T., Bartneck, M., Borkham-Kamphorst, E., Nattermann, J., Lammers, T., Tacke, F., & Weiskirchen, R. (2016) · Frontiers in Pharmacology

Liver physiology and pathologyLiver Disease Diagnosis and Treatment

Cited by 97

Iron Oxide‐Labeled Collagen Scaffolds for Non‐Invasive MR Imaging in Tissue Engineering

Mertens, M. E., Hermann, A., Bühren, A., Olde‐Damink, L., Möckel, D., Gremse, F., Ehling, J., Kiessling, F., & Lammers, T. (2014) · Advanced Functional Materials

Advanced MRI Techniques and ApplicationsTissue Engineering and Regenerative Medicine

Cited by 93

PBCA-based polymeric microbubbles for molecular imaging and drug delivery

Koczera, P., Appold, L., Shi, Y., Liu, M., Dasgupta, A., Pathak, V., Ojha, T., Fokong, S., Wu, Z., van Zandvoort, M., et al. (2017) · Journal of Controlled Release

Ultrasound and Hyperthermia ApplicationsPhotoacoustic and Ultrasonic Imaging

Cited by 85

Imaging-assisted anticancer nanotherapy

Dasgupta, A., Biancacci, I., Kiessling, F., & Lammers, T. (2020) · Theranostics

Nanoparticle-Based Drug DeliveryNanoplatforms for cancer theranostics

Cited by 74

USPIO-labeled textile materials for non-invasive MR imaging of tissue-engineered vascular grafts

Mertens, M. E., Koch, S., Schuster, P., Wehner, J., Wu, Z., Gremse, F., Schulz, V., Rongen, L., Wolf, F., Frese, J., et al. (2015) · Biomaterials

Tissue Engineering and Regenerative MedicineAdvanced MRI Techniques and Applications

Cited by 71

Monitoring EPR Effect Dynamics during Nanotaxane Treatment with Theranostic Polymeric Micelles

Biancacci, I., De Lorenzi, F., Theek, B., Bai, X., May, J., Consolino, L., Baues, M., Moeckel, D., Gremse, F., von Stillfried, S., et al. (2022) · Advanced Science

Nanoparticle-Based Drug DeliveryNanoplatforms for cancer theranostics

Cited by 68