Soininen, Hilkka

Dietary changes and cognition over 2 years within a multidomain intervention trial—The Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)

Lehtisalo, J., Levälahti, E., Lindström, J., Hänninen, T., Paajanen, T., Peltonen, M., Antikainen, R., Laatikainen, T., Strandberg, T., Soininen, H., et al. (2019) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchNutritional Studies and Diet

Cited by 95

Association of Rare APOE Missense Variants V236E and R251G With Risk of Alzheimer Disease

Le Guen, Y., Belloy, M. E., Grenier-Boley, B., de Rojas, I., Castillo-Morales, A., Jansen, I., Nicolas, A., Bellenguez, C., Dalmasso, C., Küçükali, F., et al. (2022) · JAMA Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 93

Healthy ageing through internet counselling in the elderly: the HATICE randomised controlled trial for the prevention of cardiovascular disease and cognitive impairment

Richard, E., Jongstra, S., Soininen, H., Brayne, C., Moll van Charante, E. P., Meiller, Y., van der Groep, B., Beishuizen, C. R. L., Mangialasche, F., Barbera, M., et al. (2016) · BMJ Open

Technology Use by Older AdultsMobile Health and mHealth Applications

Cited by 92

Prevalence of the apolipoprotein E ε4 allele in amyloid β positive subjects across the spectrum of Alzheimer's disease

Mattsson, N., Groot, C., Jansen, W. J., Landau, S. M., Villemagne, V. L., Engelborghs, S., Mintun, M. M., Lleo, A., Molinuevo, J. L., Jagust, W. J., et al. (2018) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 88

Phosphorylated eukaryotic translation factor 4E is elevated in Alzheimer brain

Li, X., An, W.-L., Alafuzoff, I., Soininen, H., Winblad, B., & Pei, J.-J. (2004) · NeuroReport

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 84

An epigenome-wide association study of Alzheimer's disease blood highlights robust DNA hypermethylation in the HOXB6 gene

Roubroeks, J. A. Y., Smith, A. R., Smith, R. G., Pishva, E., Ibrahim, Z., Sattlecker, M., Hannon, E. J., Kłoszewska, I., Mecocci, P., Soininen, H., et al. (2020) · Neurobiology of Aging

Epigenetics and DNA MethylationDementia and Cognitive Impairment Research

Cited by 82

Risk for non-insulindependent diabetes in the normoglycaemic elderly is associated with impaired cognitive function

Vanhanen, M., Koivisto, K., Karjalainen, L., Helkala, E.-L., Laakso, M., Soininen, H., & Riekkinen, P. (1997) · NeuroReport

Dementia and Cognitive Impairment ResearchDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 77

Genetic loci associated with Alzheimer's disease and cerebrospinal fluid biomarkers in a Finnish case–control cohort

Elias-Sonnenschein, L. S., Helisalmi, S., Natunen, T., Hall, A., Paajanen, T., Herukka, S.-K., Laitinen, M., Remes, A. M., Koivisto, A. M., Mattila, K. M., et al. (2013) · PLoS ONE

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 70

Transcriptomics and mechanistic elucidation of Alzheimer's disease risk genes in the brain and in vitro models

Martiskainen, H., Viswanathan, J., Nykänen, N.-P., Kurki, M., Helisalmi, S., Natunen, T., Sarajärvi, T., Kurkinen, K. M. A., Pursiheimo, J.-P., Rauramaa, T., et al. (2015) · Neurobiology of Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 70

Experiences of dementia and attitude towards prevention: a qualitative study among older adults participating in a prevention trial

groups, F. T. M.-A. A. H., Rosenberg, A., Coley, N., Soulier, A., Kulmala, J., Soininen, H., Andrieu, S., Kivipelto, M., & Barbera, M. (2020) · BMC Geriatrics

Dementia and Cognitive Impairment ResearchAging and Gerontology Research

Cited by 69

Dementia prevention: The potential long‐term cost‐effectiveness of the FINGER prevention program

Wimo, A., Handels, R., Antikainen, R., Eriksdotter, M., Jönsson, L., Knapp, M., Kulmala, J., Laatikainen, T., Lehtisalo, J., Peltonen, M., et al. (2023) · Alzheimer's & Dementia

Dementia and Cognitive Impairment ResearchHealth Systems, Economic Evaluations, Quality of Life

Cited by 66

Safety of Lumbar Puncture Procedures in Patients with Alzheimers Disease

Peskind, E., Nordberg, A., Darreh-Shori, T., & Soininen, H. (2009) · Current Alzheimer Research

Cerebrospinal fluid and hydrocephalusNeurosurgical Procedures and Complications

Cited by 66

Decreased plasma β‐amyloid in the Alzheimer's disease APP A 673 Tvariant carriers

Martiskainen, H., Herukka, S., Stančáková, A., Paananen, J., Soininen, H., Kuusisto, J., Laakso, M., & Hiltunen, M. (2017) · Annals of Neurology

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 64

Stability of graph theoretical measures in structural brain networks in Alzheimer’s disease

Mårtensson, G., Pereira, J. B., Mecocci, P., Vellas, B., Tsolaki, M., Kłoszewska, I., Soininen, H., Lovestone, S., Simmons, A., Volpe, G., et al. (2018) · Scientific Reports

Functional Brain Connectivity StudiesComplex Network Analysis Techniques

Cited by 60

Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood

Proitsi, P., Lee, S. H., Lunnon, K., Keohane, A., Powell, J., Troakes, C., Al-Sarraj, S., Furney, S., Soininen, H., Kłoszewska, I., et al. (2014) · Neurobiology of Aging

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 57

Five-class differential diagnostics of neurodegenerative diseases using random undersampling boosting

Tong, T., Ledig, C., Guerrero, R., Schuh, A., Koikkalainen, J., Tolonen, A., Rhodius, H., Barkhof, F., Tijms, B., Lemstra, A. W., et al. (2017) · NeuroImage: Clinical

Dementia and Cognitive Impairment ResearchArtificial Intelligence in Healthcare

Cited by 54

Decreased somatostatin-like immunoreactivity in cerebral cortex and cerebrospinal fluid in Alzheimer's disease

Reinikainen, K. J., Riekkinen, P. J., Jolkkonen, J., Kosma, V.-M., & Soininen, H. (1987) · Brain Research

Alzheimer's disease research and treatmentsDementia and Cognitive Impairment Research

Cited by 54

Single-Domain Amnestic Mild Cognitive Impairment Identified by Cluster Analysis Predicts Alzheimer's Disease in the European Prospective DESCRIPA Study

Damian, M., Hausner, L., Jekel, K., Richter, M., Froelich, L., Almkvist, O., Boada, M., Bullock, R., De Deyn, P. P., Frisoni, G. B., et al. (2013) · Dementia and Geriatric Cognitive Disorders

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 53

Prognostic polypeptide blood plasma biomarkers of Alzheimer's disease progression

Yang, H., Lyutvinskiy, Y., Herukka, S.-K., Soininen, H., Rutishauser, D., & Zubarev, R. A. (2014) · Journal of Alzheimer's Disease

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 52

Overexpression of APP provides neuroprotection in the absence of functional benefit following middle cerebral artery occlusion in rats

Clarke, J., Thornell, A., Corbett, D., Soininen, H., Hiltunen, M., & Jolkkonen, J. (2007) · European Journal of Neuroscience

Alzheimer's disease research and treatmentsAcute Ischemic Stroke Management

Cited by 50

Midlife CAIDE Dementia Risk Score and Dementia-Related Brain Changes up to 30 Years Later on Magnetic Resonance Imaging

Vuorinen, M., Spulber, G., Damangir, S., Niskanen, E., Ngandu, T., Soininen, H., Kivipelto, M., & Solomon, A. (2015) · Journal of Alzheimer's Disease

Dementia and Cognitive Impairment ResearchCerebrovascular and genetic disorders

Cited by 48

CSF Aβ42, Tau and Phosphorylated Tau Correlate with Medial Temporal Lobe Atrophy

Herukka, S.-K., Pennanen, C., Soininen, H., & Pirttilä, T. (2008) · Journal of Alzheimer's Disease

Dementia and Cognitive Impairment ResearchAlzheimer's disease research and treatments

Cited by 47

Urinary metabolic phenotyping for Alzheimer’s disease

Kurbatova, N., Garg, M., Whiley, L., Chekmeneva, E., Jiménez, B., Gómez-Romero, M., Pearce, J., Kimhofer, T., D’Hondt, E., Soininen, H., et al. (2020) · Scientific Reports

Metabolomics and Mass Spectrometry StudiesDementia and Cognitive Impairment Research

Cited by 44

Amyloid-β and Tau Dynamics in Human Brain Interstitial Fluid in Patients with Suspected Normal Pressure Hydrocephalus

Herukka, S.-K., Rummukainen, J., Ihalainen, J., von und zu Fraunberg, M., Koivisto, A. M., Nerg, O., Puli, L. K., Seppälä, T. T., Zetterberg, H., Pyykkö, O. T., et al. (2015) · Journal of Alzheimer's Disease

Alzheimer's disease research and treatmentsCerebrospinal fluid and hydrocephalus

Cited by 43