Most cited biochemistry, genetics and molecular biology papers
- Verified · note
<tt>BLAT</tt> —The <tt>BLAST</tt> -Like Alignment Tool
Kent, W. J. (2002) · Genome Research
Genomics and Phylogenetic StudiesAlgorithms and Data Compression
Cited by 8,480
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De novo transcript sequence reconstruction from RNA-seq using the Trinity platform for reference generation and analysis
Haas, B. J., Papanicolaou, A., Yassour, M., Grabherr, M., Blood, P. D., Bowden, J., Couger, M. B., Eccles, D., Li, B., Lieber, M., et al. (2013) · Nature Protocols
Genomics and Phylogenetic StudiesSingle-cell and spatial transcriptomics
Cited by 8,464
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Most mammalian mRNAs are conserved targets of microRNAs
Friedman, R. C., Farh, K. K.-H., Burge, C. B., & Bartel, D. P. (2009) · Genome Research
MicroRNA in disease regulationRNA Research and Splicing
Cited by 8,462
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Inference and analysis of cell-cell communication using CellChat
Jin, S., Guerrero-Juarez, C. F., Zhang, L., Chang, I., Ramos, R., Kuan, C.-H., Myung, P., Plikus, M. V., & Nie, Q. (2021) · Nature Communications
Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks
Cited by 8,409
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Shedding light on the cell biology of extracellular vesicles
van Niel, G., D'Angelo, G., & Raposo, G. (2018) · Nature Reviews Molecular Cell Biology
Extracellular vesicles in diseaseCellular transport and secretion
Cited by 8,369
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Finding the missing heritability of complex diseases
Manolio, T. A., Collins, F. S., Cox, N. J., Goldstein, D. B., Hindorff, L. A., Hunter, D. J., McCarthy, M. I., Ramos, E. M., Cardon, L. R., Chakravarti, A., et al. (2009) · Nature
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 8,336
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GCTA: a tool for genome-wide complex trait analysis
Yang, J., Lee, S. H., Goddard, M. E., & Visscher, P. M. (2011) · The American Journal of Human Genetics
Genetic Associations and EpidemiologyGenetic and phenotypic traits in livestock
Cited by 8,279
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How mitochondria produce reactive oxygen species
Murphy, M. P. (2009) · Biochemical Journal
Mitochondrial Function and PathologyRedox biology and oxidative stress
Cited by 8,207
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The protein kinase complement of the human genome
Manning, G., Whyte, D. B., Martinez, R., Hunter, T., & Sudarsanam, S. (2002) · Science
Protein Kinase Regulation and GTPase SignalingGenomics and Phylogenetic Studies
Cited by 8,145
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The Ensembl Variant Effect Predictor
McLaren, W., Gil, L., Hunt, S. E., Riat, H. S., Ritchie, G. R. S., Thormann, A., Flicek, P., & Cunningham, F. (2016) · Genome Biology
Genomics and Rare DiseasesGenomics and Phylogenetic Studies
Cited by 8,099
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Extracellular vesicles: Exosomes, microvesicles, and friends
Raposo, G., & Stoorvogel, W. (2013) · Journal of Cell Biology
Extracellular vesicles in diseaseCellular transport and secretion
Cited by 8,099
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deepTools2: a next generation web server for deep-sequencing data analysis
Ramírez, F., Ryan, D. P., Grüning, B., Bhardwaj, V., Kilpert, F., Richter, A. S., Heyne, S., Dündar, F., & Manke, T. (2016) · Nucleic Acids Research
Genomics and Phylogenetic StudiesGenomics and Chromatin Dynamics
Cited by 8,096
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The STRING database in 2021: customizable protein–protein networks, and functional characterization of user-uploaded gene/measurement sets
Szklarczyk, D., Gable, A. L., Nastou, K. C., Lyon, D., Kirsch, R., Pyysalo, S., Doncheva, N. T., Legeay, M., Fang, T., Bork, P., et al. (2021) · Nucleic Acids Research
Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies
Cited by 8,056
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Molecular Evolution and Phylogenetics
Nei, M., & Kumar, S. (2000)
Genomics and Phylogenetic StudiesEvolution and Genetic Dynamics
Cited by 8,012
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Circular RNAs are a large class of animal RNAs with regulatory potency
Memczak, S., Jens, M., Elefsinioti, A., Torti, F., Krueger, J., Rybak, A., Maier, L., Mackowiak, S. D., Gregersen, L. H., Munschauer, M., et al. (2013) · Nature
Circular RNAs in diseasesRNA Research and Splicing
Cited by 7,990
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Natural RNA circles function as efficient microRNA sponges
Hansen, T. B., Jensen, T. I., Clausen, B. H., Bramsen, J. B., Finsen, B., Damgaard, C. K., & Kjems, J. (2013) · Nature
Circular RNAs in diseasesMicroRNA in disease regulation
Cited by 7,985
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Circulating microRNAs as stable blood-based markers for cancer detection
Mitchell, P. S., Parkin, R. K., Kroh, E. M., Fritz, B. R., Wyman, S. K., Pogosova-Agadjanyan, E. L., Peterson, A., Noteboom, J., O'Briant, K. C., Allen, A., et al. (2008) · Proceedings of the National Academy of Sciences
MicroRNA in disease regulationExtracellular vesicles in disease
Cited by 7,969
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The MR-Base platform supports systematic causal inference across the human phenome
Hemani, G., Zheng, J., Elsworth, B., Wade, K. H., Haberland, V., Baird, D., Laurin, C., Burgess, S., Bowden, J., Langdon, R., et al. (2018) · eLife
Genetic Associations and EpidemiologyBioinformatics and Genomic Networks
Cited by 7,959
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The Cancer Cell Line Encyclopedia enables predictive modelling of anticancer drug sensitivity
Barretina, J., Caponigro, G., Stransky, N., Venkatesan, K., Margolin, A. A., Kim, S., Wilson, C. J., Lehár, J., Kryukov, G. V., Sonkin, D., et al. (2012) · Nature
Cancer Genomics and DiagnosticsComputational Drug Discovery Methods
Cited by 7,950
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Prediction of Total Genetic Value Using Genome-Wide Dense Marker Maps
Meuwissen, T. H. E., Hayes, B. J., & Goddard, M. E. (2001) · Genetics
Genetic and phenotypic traits in livestockGenetic Mapping and Diversity in Plants and Animals
Cited by 7,917
- Verified
Diversity of the Human Intestinal Microbial Flora
Eckburg, P. B., Bik, E. M., Bernstein, C. N., Purdom, E., Dethlefsen, L., Sargent, M., Gill, S. R., Nelson, K. E., & Relman, D. A. (2005) · Science
Gut microbiota and healthMicrobial Community Ecology and Physiology
Cited by 7,913
- Verified
A map of human genome variation from population-scale sequencing.
The 1000 Genomes Project Consortium (2010) · Nature
Genetic Associations and EpidemiologyGenomics and Rare Diseases
Cited by 7,877
- Verified
A scaling normalization method for differential expression analysis of RNA-seq data
Robinson, M. D., & Oshlack, A. (2010) · Genome Biology
Gene expression and cancer classificationGenomics and Phylogenetic Studies
Cited by 7,876
- Verified
Cancer Genome Landscapes
Vogelstein, B., Papadopoulos, N., Velculescu, V. E., Zhou, S., Diaz, L. A., & Kinzler, K. W. (2013) · Science
Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer
Cited by 7,863
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