Most cited biochemistry, genetics and molecular biology papers
- Verified
Integrative analysis of 111 reference human epigenomes
Roadmap Epigenomics Consortium, Kundaje, A., Meuleman, W., Ernst, J., Bilenky, M., Yen, A., Heravi-Moussavi, A., Kheradpour, P., Zhang, Z., Wang, J., et al. (2015) · Nature
Genomics and Chromatin DynamicsEpigenetics and DNA Methylation
Cited by 6,368
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Reference sequence (RefSeq) database at NCBI: current status, taxonomic expansion, and functional annotation
O'Leary, N. A., Wright, M. W., Brister, J. R., Ciufo, S., Haddad, D., McVeigh, R., Rajput, B., Robbertse, B., Smith-White, B., Ako-Adjei, D., et al. (2016) · Nucleic Acids Research
Genomics and Phylogenetic StudiesBiomedical Text Mining and Ontologies
Cited by 6,357
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Improved Prediction of Signal Peptides: SignalP 3.0
Dyrløv Bendtsen, J., Nielsen, H., von Heijne, G., & Brunak, S. (2004) · Journal of Molecular Biology
Machine Learning in BioinformaticsProtein Structure and Dynamics
Cited by 6,350
- Verified
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
Jaenisch, R., & Bird, A. (2003) · Nature Genetics
Epigenetics and DNA MethylationGenetic Syndromes and Imprinting
Cited by 6,325
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Efficient in vitro synthesis of biologically active RNA and RNA hybridization probes from plasmids containing a bacteriophage SP6 promoter
Melton, D. A., Krieg, P. A., Rebagliati, M. R., Maniatis, T., Zinn, K., & Green, M. R. (1984) · Nucleic Acids Research
Molecular Biology Techniques and ApplicationsRNA and protein synthesis mechanisms
Cited by 6,324
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ClueGO: a Cytoscape plug-in to decipher functionally grouped gene ontology and pathway annotation networks
Bindea, G., Mlecnik, B., Hackl, H., Charoentong, P., Tosolini, M., Kirilovsky, A., Fridman, W.-H., Pagès, F., Trajanoski, Z., & Galon, J. (2009) · Bioinformatics
Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies
Cited by 6,280
- Verified
REVIGO summarizes and visualizes long lists of gene ontology terms
Supek, F., Bošnjak, M., Škunca, N., & Šmuc, T. (2011) · PLoS ONE
Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies
Cited by 6,264
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Twenty-Year Follow-up of a Randomized Trial Comparing Total Mastectomy, Lumpectomy, and Lumpectomy plus Irradiation for the Treatment of Invasive Breast Cancer
Fisher, B., Anderson, S., Bryant, J., Margolese, R. G., Deutsch, M., Fisher, E. R., Jeong, J.-H., & Wolmark, N. (2002) · New England Journal of Medicine
Breast Cancer Treatment StudiesBreast Lesions and Carcinomas
Cited by 6,249
- Verified
The gut microbiota as an environmental factor that regulates fat storage
Bäckhed, F., Ding, H., Wang, T., Hooper, L. V., Koh, G. Y., Nagy, A., Semenkovich, C. F., & Gordon, J. I. (2004) · Proceedings of the National Academy of Sciences
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 6,245
- Verified
The <tt>sva</tt> package for removing batch effects and other unwanted variation in high-throughput experiments
Leek, J. T., Johnson, W. E., Parker, H. S., Jaffe, A. E., & Storey, J. D. (2012) · Bioinformatics
Gene expression and cancer classificationSingle-cell and spatial transcriptomics
Cited by 6,231
- Verified
Amino acid substitution matrices from protein blocks.
Henikoff, S., & Henikoff, J. G. (1992) · Proceedings of the National Academy of Sciences
Genomics and Phylogenetic StudiesFractal and DNA sequence analysis
Cited by 6,218
- Verified
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
Sarbassov, D. D., Guertin, D. A., Ali, S. M., & Sabatini, D. M. (2005) · Science
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 6,216
- Verified
Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.
Wang, G. L., Jiang, B. H., Rue, E. A., & Semenza, G. L. (1995) · Proceedings of the National Academy of Sciences
Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment
Cited by 6,212
- Verified
BUSCO Update: Novel and Streamlined Workflows along with Broader and Deeper Phylogenetic Coverage for Scoring of Eukaryotic, Prokaryotic, and Viral Genomes
Manni, M., Berkeley, M. R., Seppey, M., Simão, F. A., & Zdobnov, E. M. (2021) · Molecular Biology and Evolution
Genomics and Phylogenetic StudiesChromosomal and Genetic Variations
Cited by 6,187
- Verified
Biogenesis, Secretion, and Intercellular Interactions of Exosomes and Other Extracellular Vesicles
Colombo, M., Raposo, G., & Théry, C. (2014) · Annual Review of Cell and Developmental Biology
Extracellular vesicles in diseaseCellular transport and secretion
Cited by 6,186
- Verified
A general framework for estimating the relative pathogenicity of human genetic variants
Kircher, M., Witten, D. M., Jain, P., O'Roak, B. J., Cooper, G. M., & Shendure, J. (2014) · Nature Genetics
Genomics and Rare DiseasesGenetic Associations and Epidemiology
Cited by 6,183
- Verified
Epigenetic programming by maternal behavior
Weaver, I. C. G., Cervoni, N., Champagne, F. A., D'Alessio, A. C., Sharma, S., Seckl, J. R., Dymov, S., Szyf, M., & Meaney, M. J. (2004) · Nature Neuroscience
Epigenetics and DNA MethylationStress Responses and Cortisol
Cited by 6,177
- Verified
Obesity alters gut microbial ecology
Ley, R. E., Bäckhed, F., Turnbaugh, P., Lozupone, C. A., Knight, R. D., & Gordon, J. I. (2005) · Proceedings of the National Academy of Sciences
Gut microbiota and healthAdipokines, Inflammation, and Metabolic Diseases
Cited by 6,176
- Verified
Agar and broth dilution methods to determine the minimal inhibitory concentration (MIC) of antimicrobial substances
Wiegand, I., Hilpert, K., & Hancock, R. E. W. (2008) · Nature Protocols
Bacterial Identification and Susceptibility TestingAntibiotic Resistance in Bacteria
Cited by 6,156
- Verified
voom: precision weights unlock linear model analysis tools for RNA-seq read counts
Law, C. W., Chen, Y., Shi, W., & Smyth, G. K. (2014) · Genome Biology
Gene expression and cancer classificationGenomics and Phylogenetic Studies
Cited by 6,155
- Verified
Pfam: the protein families database
Finn, R. D., Bateman, A., Clements, J., Coggill, P., Eberhardt, R. Y., Eddy, S. R., Heger, A., Hetherington, K., Holm, L., Mistry, J., et al. (2014) · Nucleic Acids Research
Genomics and Phylogenetic StudiesEnzyme Structure and Function
Cited by 6,148
- Verified
DNA Methyltransferases Dnmt3a and Dnmt3b Are Essential for De Novo Methylation and Mammalian Development
Okano, M., Bell, D. W., Haber, D. A., & Li, E. (1999) · Cell
Epigenetics and DNA MethylationGenetic Syndromes and Imprinting
Cited by 6,143
- Verified
Towards a natural system of organisms: proposal for the domains Archaea, Bacteria, and Eucarya.
Woese, C. R., Kandler, O., & Wheelis, M. L. (1990) · Proceedings of the National Academy of Sciences
Protist diversity and phylogenyGenomics and Phylogenetic Studies
Cited by 6,128
- Verified
Developmental Plasticity and Evolution
West-Eberhard, M. J. (2003) · Oxford University Press eBooks
Evolution and Genetic DynamicsAnimal Behavior and Reproduction
Cited by 6,115
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