Most cited biochemistry, genetics and molecular biology papers
- Verified
Enzalutamide with Standard First-Line Therapy in Metastatic Prostate Cancer
Davis, I. D., Martin, A. J., Stockler, M. R., Begbie, S., Chi, K. N., Chowdhury, S., Coskinas, X., Frydenberg, M., Hague, W. E., Horvath, L. G., et al. (2019) · New England Journal of Medicine
Prostate Cancer Treatment and ResearchProstate Cancer Diagnosis and Treatment
Cited by 1,633
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PAS Domains: Internal Sensors of Oxygen, Redox Potential, and Light
Taylor, B. L., & Zhulin, I. B. (1999) · Microbiology and Molecular Biology Reviews
Hemoglobin structure and functionCircadian rhythm and melatonin
Cited by 1,632
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Metformin alters the gut microbiome of individuals with treatment-naive type 2 diabetes, contributing to the therapeutic effects of the drug
Wu, H., Esteve, E., Tremaroli, V., Khan, M. T., Caesar, R., Mannerås-Holm, L., Ståhlman, M., Olsson, L. M., Serino, M., Planas-Fèlix, M., et al. (2017) · Nature Medicine
Gut microbiota and healthMetabolism, Diabetes, and Cancer
Cited by 1,632
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Dominant and diet-responsive groups of bacteria within the human colonic microbiota
Walker, A. W., Ince, J., Duncan, S. H., Webster, L. M., Holtrop, G., Ze, X., Brown, D., Stares, M. D., Scott, P., Bergerat, A., et al. (2011) · The ISME Journal
Gut microbiota and healthProbiotics and Fermented Foods
Cited by 1,632
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Differential expression in RNA-seq: A matter of depth
Tarazona, S., García-Alcalde, F., Dopazo, J., Ferrer, A., & Conesa, A. (2011) · Genome Research
Gene expression and cancer classificationGenomics and Phylogenetic Studies
Cited by 1,632
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RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels
Yagoda, N., von Rechenberg, M., Zaganjor, E., Bauer, A. J., Yang, W. S., Fridman, D. J., Wolpaw, A. J., Smukste, I., Peltier, J. M., Boniface, J. J., et al. (2007) · Nature
Cell death mechanisms and regulationProtein Kinase Regulation and GTPase Signaling
Cited by 1,631
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Heparan sulphate proteoglycans fine-tune mammalian physiology
Bishop, J. R., Schuksz, M., & Esko, J. D. (2007) · Nature
Proteoglycans and glycosaminoglycans researchProtease and Inhibitor Mechanisms
Cited by 1,631
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Genome structural variation discovery and genotyping
Alkan, C., Coe, B. P., & Eichler, E. E. (2011) · Nature Reviews Genetics
Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms
Cited by 1,630
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Protein misfolding in the endoplasmic reticulum as a conduit to human disease
Wang, M., & Kaufman, R. J. (2016) · Nature
Endoplasmic Reticulum Stress and DiseaseHeat shock proteins research
Cited by 1,630
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Voltage-Gated Calcium Channels
Catterall, W. A. (2011) · Cold Spring Harbor Perspectives in Biology
Ion channel regulation and functionCardiac electrophysiology and arrhythmias
Cited by 1,628
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Regulation of the Hippo-YAP Pathway by G-Protein-Coupled Receptor Signaling
Yu, F.-X., Zhao, B., Panupinthu, N., Jewell, J. L., Lian, I., Wang, L. H., Zhao, J., Yuan, H., Tumaneng, K., Li, H., et al. (2012) · Cell
Hippo pathway signaling and YAP/TAZProtein Kinase Regulation and GTPase Signaling
Cited by 1,628
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Regulation of Phosphoinositide-Specific Phospholipase C
Rhee, S. G. (2001) · Annual Review of Biochemistry
Protein Kinase Regulation and GTPase SignalingPI3K/AKT/mTOR signaling in cancer
Cited by 1,628
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Cellular mechanotransduction: putting all the pieces together again
Ingber, D. E. (2006) · The FASEB Journal
Cellular Mechanics and InteractionsCell Adhesion Molecules Research
Cited by 1,627
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A functional genetic approach identifies the PI3K pathway as a major determinant of trastuzumab resistance in breast cancer
Berns, K., Horlings, H. M., Hennessy, B. T., Madiredjo, M., Hijmans, E. M., Beelen, K., Linn, S. C., Gonzalez-Angulo, A. M., Stemke-Hale, K., Hauptmann, M., et al. (2007) · Cancer Cell
PI3K/AKT/mTOR signaling in cancerHER2/EGFR in Cancer Research
Cited by 1,627
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The roles of intracellular protein-degradation pathways in neurodegeneration
Rubinsztein, D. C. (2006) · Nature
Autophagy in Disease and TherapyUbiquitin and proteasome pathways
Cited by 1,625
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Chk1 is an essential kinase that is regulated by Atr and required for the G 2 /M DNA damage checkpoint
Liu, Q., Guntuku, S., Cui, X.-S., Matsuoka, S., Cortez, D., Tamai, K., Luo, G., Carattini-Rivera, S., DeMayo, F., Bradley, A., et al. (2000) · Genes & Development
DNA Repair MechanismsCancer-related Molecular Pathways
Cited by 1,625
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Control of pathogens and pathobionts by the gut microbiota
Kamada, N., Chen, G. Y., Inohara, N., & Núñez, G. (2013) · Nature Immunology
Gut microbiota and healthClostridium difficile and Clostridium perfringens research
Cited by 1,625
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Engineered CRISPR-Cas9 nucleases with altered PAM specificities
Kleinstiver, B. P., Prew, M. S., Tsai, S. Q., Topkar, V. V., Nguyen, N. T., Zheng, Z., Gonzales, A. P. W., Li, Z., Peterson, R. T., Yeh, J.-R. J., et al. (2015) · Nature
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 1,624
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Bias due to participant overlap in two‐sample Mendelian randomization
Burgess, S., Davies, N. M., & Thompson, S. G. (2016) · Genetic Epidemiology
Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques
Cited by 1,624
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Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
Murtaza, M., Dawson, S.-J., Tsui, D. W. Y., Gale, D., Forshew, T., Piskorz, A. M., Parkinson, C., Chin, S.-F., Kingsbury, Z., Wong, A. S. C., et al. (2013) · Nature
Cancer Genomics and DiagnosticsCancer Immunotherapy and Biomarkers
Cited by 1,624
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TET enzymes, TDG and the dynamics of DNA demethylation
Kohli, R. M., & Zhang, Y. (2013) · Nature
Epigenetics and DNA MethylationDNA Repair Mechanisms
Cited by 1,623
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γH2AX and cancer
Bonner, W. M., Redon, C. E., Dickey, J. S., Nakamura, A. J., Sedelnikova, O. A., Solier, S., & Pommier, Y. (2008) · Nature reviews. Cancer
DNA Repair MechanismsEffects of Radiation Exposure
Cited by 1,623
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Genome evolution in yeasts
Dujon, B., Sherman, D., Fischer, G., Durrens, P., Casaregola, S., Lafontaine, I., de Montigny, J., Marck, C., Neuvéglise, C., Talla, E., et al. (2004) · Nature
Fungal and yeast genetics researchYeasts and Rust Fungi Studies
Cited by 1,623
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Mechanisms of Cellular Senescence: Cell Cycle Arrest and Senescence Associated Secretory Phenotype
Kumari, R., & Jat, P. (2021) · Frontiers in Cell and Developmental Biology
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,622
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