Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Protocols to detect senescence-associated beta-galactosidase (SA-βgal) activity, a biomarker of senescent cells in culture and in vivo

Debacq-Chainiaux, F., Erusalimsky, J. D., Campisi, J., & Toussaint, O. (2009) · Nature Protocols

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,668

Mechanisms of Hippo pathway regulation

Meng, Z., Moroishi, T., & Guan, K.-L. (2016) · Genes & Development

Hippo pathway signaling and YAP/TAZMicrotubule and mitosis dynamics

Cited by 1,667

The muscular dystrophies

Emery, A. E. (2002) · The Lancet

Muscle Physiology and DisordersCardiomyopathy and Myosin Studies

Cited by 1,667

Wisdom of crowds for robust gene network inference

The DREAM5 Consortium, Marbach, D., Costello, J. C., Küffner, R., Vega, N. M., Prill, R. J., Camacho, D. M., Allison, K. R., Kellis, M., Collins, J. J., et al. (2012) · Nature Methods

Gene Regulatory Network AnalysisMicrobial Metabolic Engineering and Bioproduction

Cited by 1,667

The support of human genetic evidence for approved drug indications

Nelson, M. R., Tipney, H., Painter, J. L., Shen, J., Nicoletti, P., Shen, Y., Floratos, A., Sham, P. C., Li, M. J., Wang, J., et al. (2015) · Nature Genetics

Genetic Associations and EpidemiologyComputational Drug Discovery Methods

Cited by 1,666

Systemically Injected Exosomes Targeted to EGFR Deliver Antitumor MicroRNA to Breast Cancer Cells

Ohno, S.-I., Takanashi, M., Sudo, K., Ueda, S., Ishikawa, A., Matsuyama, N., Fujita, K., Mizutani, T., Ohgi, T., Ochiya, T., et al. (2013) · Molecular Therapy

Extracellular vesicles in diseaseRNA Interference and Gene Delivery

Cited by 1,666

Carnitine—metabolism and functions

Bremer, J. (1983) · Physiological Reviews

Metabolism and Genetic DisordersLipid metabolism and biosynthesis

Cited by 1,666

DNA repair pathways as targets for cancer therapy

Helleday, T., Petermann, E., Lundin, C., Hodgson, B., & Sharma, R. A. (2008) · Nature Reviews Cancer

DNA Repair MechanismsPARP inhibition in cancer therapy

Cited by 1,666

Transcriptional paradigms in mammalian mitochondrial biogenesis and function

Scarpulla, R. C. (2008) · Physiological Reviews

Mitochondrial Function and PathologyAdipose Tissue and Metabolism

Cited by 1,666

Association between Microdeletion and Microduplication at 16p11.2 and Autism

Weiss, L. A., Shen, Y., Korn, J. M., Arking, D. E., Miller, D. T., Fossdal, R., Saemundsen, E., Stefansson, H., Ferreira, M. A. R., Green, T., et al. (2008) · New England Journal of Medicine

Genomic variations and chromosomal abnormalitiesAutism Spectrum Disorder Research

Cited by 1,666

A N EW A PPROACH TO D ECODING L IFE : Systems Biology

Ideker, T., Galitski, T., & Hood, L. (2001) · Annual Review of Genomics and Human Genetics

Bioinformatics and Genomic NetworksGene Regulatory Network Analysis

Cited by 1,664

Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells.

Cao, Z., Umek, R. M., & McKnight, S. L. (1991) · Genes & Development

Peroxisome Proliferator-Activated ReceptorsAdipose Tissue and Metabolism

Cited by 1,663

An auxin-based degron system for the rapid depletion of proteins in nonplant cells

Nishimura, K., Fukagawa, T., Takisawa, H., Kakimoto, T., & Kanemaki, M. (2009) · Nature Methods

Ubiquitin and proteasome pathwaysProtein Degradation and Inhibitors

Cited by 1,663

Self-propagation of pathogenic protein aggregates in neurodegenerative diseases

Jucker, M., & Walker, L. C. (2013) · Nature

Prion Diseases and Protein MisfoldingAlzheimer's disease research and treatments

Cited by 1,663

Toward Automatic Reconstruction of a Highly Resolved Tree of Life

Ciccarelli, F. D., Doerks, T., von Mering, C., Creevey, C. J., Snel, B., & Bork, P. (2006) · Science

Genomics and Phylogenetic StudiesProtist diversity and phylogeny

Cited by 1,663

Isolation of a tumor factor responsible for angiogenesis

Folkman, J., Merler, E., Abernathy, C., & Williams, G. (1971) · The Journal of Experimental Medicine

Angiogenesis and VEGF in CancerLymphatic System and Diseases

Cited by 1,663

Intrinsic and extrinsic contributions to stochasticity in gene expression

Swain, P. S., Elowitz, M. B., & Siggia, E. D. (2002) · Proceedings of the National Academy of Sciences

Gene Regulatory Network Analysisstochastic dynamics and bifurcation

Cited by 1,661

TET-mediated active DNA demethylation: mechanism, function and beyond

Wu, X., & Zhang, Y. (2017) · Nature Reviews Genetics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 1,661

An ecological and evolutionary perspective on human–microbe mutualism and disease

Dethlefsen, L., McFall-Ngai, M., & Relman, D. A. (2007) · Nature

Gut microbiota and healthOral microbiology and periodontitis research

Cited by 1,660

CNVnator: An approach to discover, genotype, and characterize typical and atypical CNVs from family and population genome sequencing

Abyzov, A., Urban, A. E., Snyder, M., & Gerstein, M. (2011) · Genome Research

Genomic variations and chromosomal abnormalitiesGenomics and Phylogenetic Studies

Cited by 1,658

Forskolin: unique diterpene activator of adenylate cyclase in membranes and in intact cells.

Seamon, K. B., Padgett, W., & Daly, J. W. (1981) · Proceedings of the National Academy of Sciences

Phosphodiesterase function and regulationReceptor Mechanisms and Signaling

Cited by 1,658

Systematic identification of trans eQTLs as putative drivers of known disease associations

Westra, H.-J., Peters, M. J., Esko, T., Yaghootkar, H., Schurmann, C., Kettunen, J., Christiansen, M. W., Fairfax, B. P., Schramm, K., Powell, J. E., et al. (2013) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,658

Super-resolution fluorescence microscopy

Huang, B., Bates, M., & Zhuang, X. (2009) · Annual Review of Biochemistry

Advanced Fluorescence Microscopy TechniquesCell Image Analysis Techniques

Cited by 1,657

Mechanical forces direct stem cell behaviour in development and regeneration

Vining, K. H., & Mooney, D. J. (2017) · Nature Reviews Molecular Cell Biology

Cellular Mechanics and InteractionsTissue Engineering and Regenerative Medicine

Cited by 1,656