Most cited biochemistry, genetics and molecular biology papers
- Verified
Likelihood models for detecting positively selected amino acid sites and applications to the HIV-1 envelope gene
Nielsen, R., & Yang, Z. (1998) · Genetics
Evolution and Genetic DynamicsGenomics and Phylogenetic Studies
Cited by 1,622
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Highly efficient Cas9-mediated transcriptional programming
Chavez, A., Scheiman, J., Vora, S., Pruitt, B. W., Tuttle, M., P R Iyer, E., Lin, S., Kiani, S., Guzman, C. D., Wiegand, D. J., et al. (2015) · Nature Methods
CRISPR and Genetic EngineeringPluripotent Stem Cells Research
Cited by 1,622
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Senescence surveillance of pre-malignant hepatocytes limits liver cancer development
Kang, T.-W., Yevsa, T., Woller, N., Hoenicke, L., Wuestefeld, T., Dauch, D., Hohmeyer, A., Gereke, M., Rudalska, R., Potapova, A., et al. (2011) · Nature
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,621
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Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors
Casanovas, O., Hicklin, D. J., Bergers, G., & Hanahan, D. (2005) · Cancer Cell
Angiogenesis and VEGF in CancerCancer, Hypoxia, and Metabolism
Cited by 1,621
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Three-dimensional intact-tissue sequencing of single-cell transcriptional states
Wang, X., Allen, W. E., Wright, M. A., Sylwestrak, E. L., Samusik, N., Vesuna, S., Evans, K., Liu, C., Ramakrishnan, C., Liu, J., et al. (2018) · Science
Single-cell and spatial transcriptomicsMolecular Biology Techniques and Applications
Cited by 1,620
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SoupX removes ambient RNA contamination from droplet-based single-cell RNA sequencing data
Young, M. D., & Behjati, S. (2020) · GigaScience
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 1,619
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Nutrition Needs of Mammalian Cells in Tissue Culture
Eagle, H. (1955) · Science
Viral Infectious Diseases and Gene Expression in InsectsCancer and biochemical research
Cited by 1,619
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The role of non-coding RNAs in oncology
Slack, F. J., & Chinnaiyan, A. M. (2019) · Cell
Cancer-related molecular mechanisms researchMicroRNA in disease regulation
Cited by 1,619
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AMP-activated protein kinase induces a p53-dependent metabolic checkpoint
Jones, R. G., Plas, D. R., Kubek, S., Buzzai, M., Mu, J., Xu, Y., Birnbaum, M. J., & Thompson, C. B. (2005) · Molecular Cell
Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer
Cited by 1,619
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Beyond oxidative stress: an immunologist's guide to reactive oxygen species
Nathan, C., & Cunningham-Bussel, A. (2013) · Nature Reviews Immunology
Redox biology and oxidative stressNeutrophil, Myeloperoxidase and Oxidative Mechanisms
Cited by 1,619
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The Inflammasome NLRs in Immunity, Inflammation, and Associated Diseases
Davis, B. K., Wen, H., & Ting, J. P.-Y. (2011) · Annual Review of Immunology
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 1,618
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Detection of Mutations in EGFR in Circulating Lung-Cancer Cells
Maheswaran, S., Sequist, L. V., Nagrath, S., Ulkus, L., Brannigan, B., Collura, C. V., Inserra, E., Diederichs, S., Iafrate, A. J., Bell, D. W., et al. (2008) · New England Journal of Medicine
Cancer Genomics and DiagnosticsLung Cancer Treatments and Mutations
Cited by 1,617
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Rational design of highly active sgRNAs for CRISPR-Cas9-mediated gene inactivation
Doench, J. G., Hartenian, E., Graham, D. B., Tothova, Z., Hegde, M., Smith, I., Sullender, M., Ebert, B. L., Xavier, R. J., & Root, D. E. (2014) · Nature Biotechnology
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 1,617
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The integrated stress response: From mechanism to disease
Costa-Mattioli, M., & Walter, P. (2020) · Science
Endoplasmic Reticulum Stress and DiseaseGenetics, Aging, and Longevity in Model Organisms
Cited by 1,617
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Identification and characterization of essential genes in the human genome
Wang, T., Birsoy, K., Hughes, N. W., Krupczak, K. M., Post, Y., Wei, J. J., Lander, E. S., & Sabatini, D. M. (2015) · Science
CRISPR and Genetic EngineeringChromatin Remodeling and Cancer
Cited by 1,617
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Human RISC Couples MicroRNA Biogenesis and Posttranscriptional Gene Silencing
Gregory, R. I., Chendrimada, T. P., Cooch, N., & Shiekhattar, R. (2005) · Cell
RNA Interference and Gene DeliveryMicroRNA in disease regulation
Cited by 1,617
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The Mitochondrial Carnitine Palmitoyltransferase System — From Concept to Molecular Analysis
McGarry, J. D., & Brown, N. F. (1997) · European Journal of Biochemistry
Metabolism and Genetic DisordersMitochondrial Function and Pathology
Cited by 1,616
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Regulation of myostatin activity and muscle growth
Lee, S.-J., & McPherron, A. C. (2001) · Proceedings of the National Academy of Sciences
Muscle Physiology and DisordersTGF-β signaling in diseases
Cited by 1,616
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Production of Reactive Oxygen Species by Mitochondria
Chen, Q., Vazquez, E. J., Moghaddas, S., Hoppel, C. L., & Lesnefsky, E. J. (2003) · Journal of Biological Chemistry
Mitochondrial Function and PathologyCardiac Ischemia and Reperfusion
Cited by 1,616
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Wnt/β-Catenin Signaling in Mesenchymal Progenitors Controls Osteoblast and Chondrocyte Differentiation during Vertebrate Skeletogenesis
Day, T. F., Guo, X., Garrett-Beal, L., & Yang, Y. (2005) · Developmental Cell
Wnt/β-catenin signaling in development and cancerBone Metabolism and Diseases
Cited by 1,616
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Functional insights from the structure of the 30S ribosomal subunit and its interactions with antibiotics
Carter, A. P., Clemons, W. M., Brodersen, D. E., Morgan-Warren, R. J., Wimberly, B. T., & Ramakrishnan, V. (2000) · Nature
RNA and protein synthesis mechanismsRNA modifications and cancer
Cited by 1,615
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Large-scale association analysis identifies new risk loci for coronary artery disease
The CARDIoGRAMplusC4D Consortium, Deloukas, P., DIAGRAM Consortium, CARDIOGENICS Consortium, MuTHER Consortium, Wellcome Trust Case Control Consortium, Kanoni, S., Willenborg, C., Farrall, M., Assimes, T. L., et al. (2013) · Nature Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 1,614
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NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
Rius, J., Guma, M., Schachtrup, C., Akassoglou, K., Zinkernagel, A. S., Nizet, V., Johnson, R. S., Haddad, G. G., & Karin, M. (2008) · Nature
NF-κB Signaling PathwaysCancer, Hypoxia, and Metabolism
Cited by 1,614
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Linkage disequilibrium--understanding the evolutionary past and mapping the medical future.
Slatkin, M. (2008) · Nature Reviews Genetics
Genetic Associations and EpidemiologyGenetic diversity and population structure
Cited by 1,614
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