Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat

Kelly, J. R., Borre, Y., O' Brien, C., Patterson, E., El Aidy, S., Deane, J., Kennedy, P. J., Beers, S., Scott, K., Moloney, G., et al. (2016) · Journal of Psychiatric Research

Gut microbiota and healthTryptophan and brain disorders

Cited by 1,683

Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications

Zielonka, J., Joseph, J., Sikora, A., Hardy, M., Ouari, O., Vasquez-Vivar, J., Cheng, G., Lopez, M., & Kalyanaraman, B. (2017) · Chemical Reviews

Mitochondrial Function and PathologyMolecular Sensors and Ion Detection

Cited by 1,683

Macropinocytosis of protein is an amino acid supply route in Ras-transformed cells

Commisso, C., Davidson, S. M., Soydaner-Azeloglu, R. G., Parker, S. J., Kamphorst, J. J., Hackett, S., Grabocka, E., Nofal, M., Drebin, J. A., Thompson, C. B., et al. (2013) · Nature

Cellular transport and secretionCancer, Hypoxia, and Metabolism

Cited by 1,683

Functional genomics reveal that the serine synthesis pathway is essential in breast cancer

Possemato, R., Marks, K. M., Shaul, Y. D., Pacold, M. E., Kim, D., Birsoy, K., Sethumadhavan, S., Woo, H.-K., Jang, H. G., Jha, A. K., et al. (2011) · Nature

Cancer, Hypoxia, and MetabolismAmino Acid Enzymes and Metabolism

Cited by 1,683

Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: A general strategy for targeting mutations to non-selectable genes

Mansour, S. L., Thomas, K. R., & Capecchi, M. R. (1988) · Nature

CRISPR and Genetic EngineeringAnimal Genetics and Reproduction

Cited by 1,683

Antiangiogenic therapy of experimental cancer does not induce acquired drug resistance

Boehm, T., Folkman, J., Browder, T., & O'Reilly, M. S. (1997) · Nature

Angiogenesis and VEGF in CancerCancer Cells and Metastasis

Cited by 1,683

Induced pluripotent stem cells generated without viral integration

Stadtfeld, M., Nagaya, M., Utikal, J., Weir, G., & Hochedlinger, K. (2008) · Science

Pluripotent Stem Cells ResearchCRISPR and Genetic Engineering

Cited by 1,683

The abundance and variety of carbohydrate-active enzymes in the human gut microbiota

Kaoutari, A. E., Armougom, F., Gordon, J. I., Raoult, D., & Henrissat, B. (2013) · Nature Reviews Microbiology

Gut microbiota and healthEnzyme Production and Characterization

Cited by 1,683

A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure

Zhang, Y., Talalay, P., Cho, C. G., & Posner, G. H. (1992) · Proceedings of the National Academy of Sciences

Genomics, phytochemicals, and oxidative stressBioactive Compounds and Antitumor Agents

Cited by 1,682

The MSC: An Injury Drugstore

Caplan, A. I., & Correa, D. (2011) · Cell Stem Cell

Mesenchymal stem cell researchPeriodontal Regeneration and Treatments

Cited by 1,682

Image-based analysis of lipid nanoparticle–mediated siRNA delivery, intracellular trafficking and endosomal escape

Gilleron, J., Querbes, W., Zeigerer, A., Borodovsky, A., Marsico, G., Schubert, U., Manygoats, K., Seifert, S., Andree, C., Stöter, M., et al. (2013) · Nature Biotechnology

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 1,681

chromVAR: inferring transcription-factor-associated accessibility from single-cell epigenomic data

Schep, A. N., Wu, B., Buenrostro, J. D., & Greenleaf, W. J. (2017) · Nature Methods

Genomics and Chromatin DynamicsSingle-cell and spatial transcriptomics

Cited by 1,680

Inherited DNA-Repair Gene Mutations in Men with Metastatic Prostate Cancer

Pritchard, C. C., Mateo, J., Walsh, M. F., De Sarkar, N., Abida, W., Beltran, H., Garofalo, A., Gulati, R., Carreira, S., Eeles, R., et al. (2016) · New England Journal of Medicine

BRCA gene mutations in cancerGenetic factors in colorectal cancer

Cited by 1,680

Induction of autophagy by spermidine promotes longevity

Eisenberg, T., Knauer, H., Schauer, A., Büttner, S., Ruckenstuhl, C., Carmona-Gutierrez, D., Ring, J., Schroeder, S., Magnes, C., Antonacci, L., et al. (2009) · Nature Cell Biology

Genetics, Aging, and Longevity in Model OrganismsAutophagy in Disease and Therapy

Cited by 1,680

Toward a Shared Vision for Cancer Genomic Data

Grossman, R. L., Heath, A. P., Ferretti, V., Varmus, H. E., Lowy, D. R., Kibbe, W. A., & Staudt, L. M. (2016) · New England Journal of Medicine

Cancer Genomics and DiagnosticsResearch Data Management Practices

Cited by 1,680

Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments

Bullard, J. H., Purdom, E., Hansen, K. D., & Dudoit, S. (2010) · BMC Bioinformatics

Gene expression and cancer classificationGenomics and Phylogenetic Studies

Cited by 1,680

The lipocalin protein family: structure and function

FLOWER, D. R. (1996) · Biochemical Journal

Protein Interaction Studies and Fluorescence AnalysisProtein Structure and Dynamics

Cited by 1,679

Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics

Letai, A., Bassik, M. C., Walensky, L. D., Sorcinelli, M. D., Weiler, S., & Korsmeyer, S. J. (2002) · Cancer Cell

Cell death mechanisms and regulationCancer-related Molecular Pathways

Cited by 1,677

Fatality in mice due to oversaturation of cellular microRNA/short hairpin RNA pathways

Grimm, D., Streetz, K. L., Jopling, C. L., Storm, T. A., Pandey, K., Davis, C. R., Marion, P., Salazar, F., & Kay, M. A. (2006) · Nature

RNA Interference and Gene DeliveryMicroRNA in disease regulation

Cited by 1,677

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

Um, S. H., Frigerio, F., Watanabe, M., Picard, F., Joaquin, M., Sticker, M., Fumagalli, S., Allegrini, P. R., Kozma, S. C., Auwerx, J., et al. (2004) · Nature

Metabolism, Diabetes, and CancerPI3K/AKT/mTOR signaling in cancer

Cited by 1,677

The inner junction complex of the cilia is an interaction hub that involves tubulin post-translational modifications

Khalifa, A. A. Z., Ichikawa, M., Dai, D., Kubo, S., Black, C. S., Peri, K., McAlear, T. S., Veyron, S., Yang, S. K., Vargas, J., et al. (2020) · eLife

Genetic and Kidney Cyst DiseasesMicrotubule and mitosis dynamics

Cited by 1,676

mTOR is a key modulator of ageing and age-related disease

Johnson, S. C., Rabinovitch, P. S., & Kaeberlein, M. (2013) · Nature

Genetics, Aging, and Longevity in Model OrganismsPI3K/AKT/mTOR signaling in cancer

Cited by 1,676

Hypoxia signalling in cancer and approaches to enforce tumour regression

Pouysségur, J., Dayan, F., & Mazure, N. M. (2006) · Nature

Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer

Cited by 1,676

Base editing: precision chemistry on the genome and transcriptome of living cells

Rees, H. A., & Liu, D. R. (2018) · Nature Reviews Genetics

CRISPR and Genetic EngineeringRNA regulation and disease

Cited by 1,675