Most cited biochemistry, genetics and molecular biology papers
- Verified
The endoplasmic reticulum: structure, function and response to cellular signaling
Schwarz, D. S., & Blower, M. D. (2016) · Cellular and Molecular Life Sciences
Cellular transport and secretionEndoplasmic Reticulum Stress and Disease
Cited by 1,613
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Antibiotics in early life alter the murine colonic microbiome and adiposity
Cho, I., Yamanishi, S., Cox, L., Methé, B. A., Zavadil, J., Li, K., Gao, Z., Mahana, D., Raju, K., Teitler, I., et al. (2012) · Nature
Gut microbiota and healthAnimal Nutrition and Physiology
Cited by 1,613
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UniRef: comprehensive and non-redundant UniProt reference clusters
Suzek, B. E., Huang, H., McGarvey, P., Mazumder, R., & Wu, C. H. (2007) · Bioinformatics
Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks
Cited by 1,613
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Cellular senescence mediates fibrotic pulmonary disease
Schafer, M. J., White, T. A., Iijima, K., Haak, A. J., Ligresti, G., Atkinson, E. J., Oberg, A. L., Birch, J., Salmonowicz, H., Zhu, Y., et al. (2017) · Nature Communications
Telomeres, Telomerase, and SenescenceInterstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
Cited by 1,613
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Phenotypic plasticity and the epigenetics of human disease
Feinberg, A. P. (2007) · Nature
Epigenetics and DNA MethylationBirth, Development, and Health
Cited by 1,613
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Evolution and functional impact of rare coding variation from deep sequencing of human exomes
Tennessen, J. A., Bigham, A. W., O’Connor, T. D., Fu, W., Kenny, E. E., Gravel, S., McGee, S., Do, R., Liu, X., Jun, G., et al. (2012) · Science
Genomics and Rare DiseasesGenetic Associations and Epidemiology
Cited by 1,613
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Widespread Shortening of 3′UTRs by Alternative Cleavage and Polyadenylation Activates Oncogenes in Cancer Cells
Mayr, C., & Bartel, D. P. (2009) · Cell
RNA Research and SplicingCancer-related molecular mechanisms research
Cited by 1,613
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Hypoxic microenvironment in cancer: molecular mechanisms and therapeutic interventions
Chen, Z., Han, F., Du, Y., Shi, H., & Zhou, W. (2023) · Signal Transduction and Targeted Therapy
Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer
Cited by 1,612
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Distinguishing between resistance, tolerance and persistence to antibiotic treatment
Brauner, A., Fridman, O., Gefen, O., & Balaban, N. Q. (2016) · Nature Reviews Microbiology
Bacterial Genetics and BiotechnologyAntimicrobial Resistance in Staphylococcus
Cited by 1,612
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The interplay between the intestinal microbiota and the brain
Collins, S. M., Surette, M., & Bercik, P. (2012) · Nature Reviews Microbiology
Gut microbiota and healthGastrointestinal motility and disorders
Cited by 1,611
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Retinoic Acid and Arsenic Trioxide for Acute Promyelocytic Leukemia
Lo-Coco, F., Avvisati, G., Vignetti, M., Thiede, C., Orlando, S. M., Iacobelli, S., Ferrara, F., Fazi, P., Cicconi, L., Di Bona, E., et al. (2013) · New England Journal of Medicine
Retinoids in leukemia and cellular processesAcute Myeloid Leukemia Research
Cited by 1,611
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Functional cortical neurons and astrocytes from human pluripotent stem cells in 3D culture
Paşca, A. M., Sloan, S. A., Clarke, L. E., Tian, Y., Makinson, C. D., Huber, N., Kim, C. H., Park, J.-Y., O'Rourke, N. A., Nguyen, K. D., et al. (2015) · Nature Methods
Pluripotent Stem Cells ResearchNeurogenesis and neuroplasticity mechanisms
Cited by 1,609
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Multi-omics Data Integration, Interpretation, and Its Application
Subramanian, I., Verma, S., Kumar, S., Jere, A., & Anamika, K. (2020) · Bioinformatics and Biology Insights
Bioinformatics and Genomic NetworksHealth, Environment, Cognitive Aging
Cited by 1,609
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Full-length mRNA-Seq from single-cell levels of RNA and individual circulating tumor cells
Ramsköld, D., Luo, S., Wang, Y.-C., Li, R., Deng, Q., Faridani, O. R., Daniels, G. A., Khrebtukova, I., Loring, J. F., Laurent, L. C., et al. (2012) · Nature Biotechnology
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 1,609
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Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction
Glinka, A., Wu, W., Delius, H., Monaghan, A. P., Blumenstock, C., & Niehrs, C. (1998) · Nature
Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation
Cited by 1,608
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Automated macromolecular model building for X-ray crystallography using ARP/wARP version 7
Langer, G., Cohen, S. X., Lamzin, V. S., & Perrakis, A. (2008) · Nature Protocols
Enzyme Structure and FunctionProtein Structure and Dynamics
Cited by 1,606
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Emerging Pathogenic Links Between Microbiota and the Gut-Lung Axis
Budden, K. F., Gellatly, S. L., Wood, D. L. A., Cooper, M. A., Morrison, M., Hugenholtz, P., & Hansbro, P. M. (2017) · Nature Reviews Microbiology
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 1,606
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Chemically defined generation of human cardiomyocytes
Burridge, P. W., Matsa, E., Shukla, P., Lin, Z. C., Churko, J. M., Ebert, A. D., Lan, F., Diecke, S., Huber, B., Mordwinkin, N. M., et al. (2014) · Nature Methods
Pluripotent Stem Cells ResearchCongenital heart defects research
Cited by 1,606
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Apoptosis in neurodegenerative disorders
Mattson, M. P. (2000) · Nature Reviews Molecular Cell Biology
Cell death mechanisms and regulationAutophagy in Disease and Therapy
Cited by 1,605
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Normalization of the Vasculature for Treatment of Cancer and Other Diseases
Goel, S., Duda, D. G., Xu, L., Munn, L. L., Boucher, Y., Fukumura, D., & Jain, R. K. (2011) · Physiological Reviews
Angiogenesis and VEGF in CancerLymphatic System and Diseases
Cited by 1,605
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Multivariable Mendelian randomization: the use of pleiotropic genetic variants to estimate causal effects.
Burgess, S., & Thompson, S. G. (2015) · American Journal of Epidemiology
Genetic Associations and EpidemiologyAdvanced Causal Inference Techniques
Cited by 1,605
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Hydrogen peroxide sensing and signaling
Veal, E. A., Day, A. M., & Morgan, B. A. (2007) · Molecular Cell
Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress
Cited by 1,604
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PID: the Pathway Interaction Database
Schaefer, C. F., Anthony, K., Krupa, S., Buchoff, J., Day, M., Hannay, T., & Buetow, K. H. (2009) · Nucleic Acids Research
Bioinformatics and Genomic NetworksBiomedical Text Mining and Ontologies
Cited by 1,603
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Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders
Durand, C. M., Betancur, C., Boeckers, T. M., Bockmann, J., Chaste, P., Fauchereau, F., Nygren, G., Rastam, M., Gillberg, I. C., Anckarsäter, H., et al. (2007) · Nature Genetics
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 1,602
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