Most cited biochemistry, genetics and molecular biology papers
- Verified
BCL-2 family proteins: changing partners in the dance towards death
Kale, J., Osterlund, E. J., & Andrews, D. W. (2018) · Cell Death & Differentiation
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 1,574
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Analysis of Fusobacterium persistence and antibiotic response in colorectal cancer
Bullman, S., Pedamallu, C. S., Sicinska, E., Clancy, T. E., Zhang, X., Cai, D., Neuberg, D., Huang, K., Guevara, F., Nelson, T., et al. (2017) · Science
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 1,574
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Structure of the insulin receptor substrate IRS-1 defines a unique signal transduction protein
Sun, X. J., Rothenberg, P., Kahn, C. R., Backer, J. M., Araki, E., Wilden, P. A., Cahill, D. A., Goldstein, B. J., & White, M. F. (1991) · Nature
Metabolism, Diabetes, and CancerProtein Kinase Regulation and GTPase Signaling
Cited by 1,574
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Estrogen and progesterone receptor testing in breast cancer: ASCO/CAP Guideline update
Allison, K. H., Hammond, M. E. H., Dowsett, M., McKernin, S. E., Carey, L. A., Fitzgibbons, P. L., Hayes, D. F., Lakhani, S. R., Chavez-MacGregor, M., Perlmutter, J., et al. (2020) · Journal of Clinical Oncology
Breast Cancer Treatment StudiesBreast Lesions and Carcinomas
Cited by 1,574
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The Genetic Structure and History of Africans and African Americans
Tishkoff, S. A., Reed, F. A., Friedlaender, F. R., Ehret, C., Ranciaro, A., Froment, A., Hirbo, J. B., Awomoyi, A. A., Bodo, J.-M., Doumbo, O., et al. (2009) · Science
Forensic and Genetic ResearchGenetic diversity and population structure
Cited by 1,573
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Induction of Ectopic Eyes by Targeted Expression of the eyeless Gene in Drosophila
Halder, G., Callaerts, P., & Gehring, W. J. (1995) · Science
Developmental Biology and Gene RegulationOcular Disorders and Treatments
Cited by 1,573
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A census of human transcription factors: function, expression and evolution
Vaquerizas, J. M., Kummerfeld, S. K., Teichmann, S. A., & Luscombe, N. M. (2009) · Nature Reviews Genetics
Genomics and Chromatin DynamicsBioinformatics and Genomic Networks
Cited by 1,573
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Redox Regulation of Fos and Jun DNA-Binding Activity in Vitro
Abate, C., Patel, L., Rauscher, F. J., & Curran, T. (1990) · Science
Redox biology and oxidative stressProtein Kinase Regulation and GTPase Signaling
Cited by 1,573
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The landscape of genomic alterations across childhood cancers
ICGC PedBrain-Seq Project, Gröbner, S. N., ICGC MMML-Seq Project, Worst, B. C., Weischenfeldt, J., Buchhalter, I., Kleinheinz, K., Rudneva, V. A., Johann, P. D., Balasubramanian, G. P., et al. (2018) · Nature
Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer
Cited by 1,572
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Single-cell transcriptional diversity is a hallmark of developmental potential
Gulati, G. S., Sikandar, S. S., Wesche, D. J., Manjunath, A., Bharadwaj, A., Berger, M. J., Ilagan, F., Kuo, A. H., Hsieh, R. W., Cai, S., et al. (2020) · Science
Single-cell and spatial transcriptomicsGene Regulatory Network Analysis
Cited by 1,571
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Size and Shape of Protein Molecules at the Nanometer Level Determined by Sedimentation, Gel Filtration, and Electron Microscopy
Erickson, H. P. (2009) · Biological Procedures Online
Protein Structure and DynamicsProtein purification and stability
Cited by 1,571
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High-Resolution CRISPR Screens Reveal Fitness Genes and Genotype-Specific Cancer Liabilities.
Hart, T., Chandrashekhar, M., Aregger, M., Steinhart, Z., Brown, K. R., MacLeod, G., Mis, M., Zimmermann, M., Fradet-Turcotte, A., Sun, S., et al. (2015) · Cell
CRISPR and Genetic EngineeringChromatin Remodeling and Cancer
Cited by 1,571
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High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
Bender, A., Krishnan, K. J., Morris, C. M., Taylor, G. A., Reeve, A. K., Perry, R. H., Jaros, E., Hersheson, J. S., Betts, J., Klopstock, T., et al. (2006) · Nature Genetics
Mitochondrial Function and PathologyParkinson's Disease Mechanisms and Treatments
Cited by 1,570
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Shank3 mutant mice display autistic-like behaviours and striatal dysfunction
Peça, J., Feliciano, C., Ting, J. T., Wang, W., Wells, M. F., Venkatraman, T. N., Lascola, C. D., Fu, Z., & Feng, G. (2011) · Nature
Genetics and Neurodevelopmental DisordersAutism Spectrum Disorder Research
Cited by 1,570
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Single-nucleotide-resolution mapping of m6A and m6Am throughout the transcriptome
Linder, B., Grozhik, A. V., Olarerin-George, A. O., Meydan, C., Mason, C. E., & Jaffrey, S. R. (2015) · Nature Methods
RNA modifications and cancerRNA regulation and disease
Cited by 1,569
- Verified
Remodeling and homeostasis of the extracellular matrix: implications for fibrotic diseases and cancer
Cox, T. R., & Erler, J. T. (2011) · Disease Models & Mechanisms
Cellular Mechanics and InteractionsTGF-β signaling in diseases
Cited by 1,569
- Verified
A genomic regulatory network for development
Davidson, E. H., Rast, J. P., Oliveri, P., Ransick, A., Calestani, C., Yuh, C.-H., Minokawa, T., Amore, G., Hinman, V., Arenas-Mena, C., et al. (2002) · Science
Developmental Biology and Gene RegulationGene Regulatory Network Analysis
Cited by 1,567
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Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.
Zamzami, N., Marchetti, P., Castedo, M., Decaudin, D., Macho, A., Hirsch, T., Susin, S. A., Petit, P. X., Mignotte, B., & Kroemer, G. (1995) · The Journal of experimental medicine
Cell death mechanisms and regulationMitochondrial Function and Pathology
Cited by 1,567
- Verified
The impact of diet and lifestyle on gut microbiota and human health
Conlon, M., & Bird, A. (2014) · Nutrients
Gut microbiota and healthProbiotics and Fermented Foods
Cited by 1,567
- Verified
mRNA-lipid nanoparticle COVID-19 vaccines: structure and stability
Schoenmaker, L., Witzigmann, D., Kulkarni, J. A., Verbeke, R., Kersten, G., Jiskoot, W., & Crommelin, D. J. A. (2021) · International Journal of Pharmaceutics
RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery
Cited by 1,566
- Verified
ComBat-seq: batch effect adjustment for RNA-seq count data
Zhang, Y., Parmigiani, G., & Johnson, W. E. (2020) · NAR Genomics and Bioinformatics
Gene expression and cancer classificationSingle-cell and spatial transcriptomics
Cited by 1,566
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Genome engineering in Saccharomyces cerevisiae using CRISPR-Cas systems
DiCarlo, J. E., Norville, J. E., Mali, P., Rios, X., Aach, J., & Church, G. M. (2013) · Nucleic Acids Research
CRISPR and Genetic EngineeringFungal and yeast genetics research
Cited by 1,566
- Verified
Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis
Brack, A. S., Conboy, M. J., Roy, S., Lee, M., Kuo, C. J., Keller, C., & Rando, T. A. (2007) · Science
Muscle Physiology and DisordersWnt/β-catenin signaling in development and cancer
Cited by 1,564
- Verified
Histone deacetylases and their inhibitors in cancer, neurological diseases and immune disorders
Falkenberg, K. J., & Johnstone, R. W. (2014) · Nature Reviews Drug Discovery
Histone Deacetylase Inhibitors ResearchEpigenetics and DNA Methylation
Cited by 1,564
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