Most cited biochemistry, genetics and molecular biology papers
- Verified
The role of pericytes in blood-vessel formation and maintenance
Bergers, G., & Song, S. (2005) · Neuro-Oncology
Angiogenesis and VEGF in CancerBarrier Structure and Function Studies
Cited by 1,584
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Hyperactive Ras in developmental disorders and cancer
Schubbert, S., Shannon, K., & Bollag, G. (2007) · Nature Reviews Cancer
Protein Tyrosine PhosphatasesProtein Kinase Regulation and GTPase Signaling
Cited by 1,583
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The Myeloma Drug Lenalidomide Promotes the Cereblon-Dependent Destruction of Ikaros Proteins
Lu, G., Middleton, R. E., Sun, H., Naniong, M., Ott, C. J., Mitsiades, C. S., Wong, K.-K., Bradner, J. E., & Kaelin, W. G. (2014) · Science
Protein Degradation and InhibitorsMultiple Myeloma Research and Treatments
Cited by 1,583
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Inhibition of Proteasome Activities and Subunit-Specific Amino-Terminal Threonine Modification by Lactacystin
Fenteany, G., Standaert, R. F., Lane, W. S., Choi, S., Corey, E. J., & Schreiber, S. L. (1995) · Science
Ubiquitin and proteasome pathwaysProtease and Inhibitor Mechanisms
Cited by 1,583
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Mediation of IGF-1-induced skeletal myotube hypertrophy by PI(3)K/Akt/mTOR and PI(3)K/Akt/GSK3 pathways
Rommel, C., Bodine, S. C., Clarke, B. A., Rossman, R., Nunez, L., Stitt, T. N., Yancopoulos, G. D., & Glass, D. J. (2001) · Nature Cell Biology
Muscle Physiology and DisordersMuscle metabolism and nutrition
Cited by 1,583
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Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell
Tyson, J. J., Chen, K. C., & Novak, B. (2003) · Current Opinion in Cell Biology
Gene Regulatory Network AnalysisMathematical Biology Tumor Growth
Cited by 1,583
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RCSB Protein Data Bank: powerful new tools for exploring 3D structures of biological macromolecules for basic and applied research and education in fundamental biology, biomedicine, biotechnology, bioengineering and energy sciences
Burley, S. K., Bhikadiya, C., Bi, C., Bittrich, S., Chen, L., Crichlow, G. V., Christie, C. H., Dalenberg, K., Di Costanzo, L., Duarte, J. M., et al. (2021) · Nucleic Acids Research
Enzyme Structure and FunctionProtein Structure and Dynamics
Cited by 1,581
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S100: a multigenic family of calcium-modulated proteins of the EF-hand type with intracellular and extracellular functional roles
Donato, R. (2001) · The International Journal of Biochemistry & Cell Biology
S100 Proteins and AnnexinsAdvanced Glycation End Products research
Cited by 1,580
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New genetic loci link adipose and insulin biology to body fat distribution
The ADIPOGen Consortium, Shungin, D., The CARDIOGRAMplusC4D Consortium, The CKDGen Consortium, The GEFOS Consortium, The GENIE Consortium, The, G. L. G. C., The, I. C. B. P., The International Endogene Consortium, Study, T. L. C., et al. (2015) · Nature
Genetic Associations and EpidemiologyAdipokines, Inflammation, and Metabolic Diseases
Cited by 1,580
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The mGluR theory of fragile X mental retardation
Bear, M. F., Huber, K. M., & Warren, S. T. (2004) · Trends in Neurosciences
Genetics and Neurodevelopmental DisordersNeuroscience and Neuropharmacology Research
Cited by 1,580
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Argonaute2, a Link Between Genetic and Biochemical Analyses of RNAi
Hammond, S. M., Boettcher, S., Caudy, A. A., Kobayashi, R., & Hannon, G. J. (2001) · Science
RNA Interference and Gene DeliveryRNA Research and Splicing
Cited by 1,580
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Forkhead transcription factor FOXO3a protects quiescent cells from oxidative stress
Kops, G. J. P. L., Dansen, T. B., Polderman, P. E., Saarloos, I., Wirtz, K. W. A., Coffer, P. J., Huang, T.-T., Bos, J. L., Medema, R. H., & Burgering, B. M. T. (2002) · Nature
FOXO transcription factor regulationRedox biology and oxidative stress
Cited by 1,580
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The oncogene and Polycomb-group gene bmi-1 regulates cell proliferation and senescence through the ink4a locus
Jacobs, J. J. L., Kieboom, K., Marino, S., DePinho, R. A., & van Lohuizen, M. (1999) · Nature
Epigenetics and DNA MethylationTelomeres, Telomerase, and Senescence
Cited by 1,580
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Mouse genomic variation and its effect on phenotypes and gene regulation.
Keane, T. M., Goodstadt, L., Danecek, P., White, M. A., Wong, K., Yalcin, B., Heger, A., Agam, A., Slater, G., Goodson, M., et al. (2011) · Nature
Genetic Mapping and Diversity in Plants and AnimalsGenetic and phenotypic traits in livestock
Cited by 1,580
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Fluorescent and colorimetric probes for detection of thiols
Chen, X., Zhou, Y., Peng, X., & Yoon, J. (2010) · Chemical Society Reviews
Sulfur Compounds in BiologyMolecular Sensors and Ion Detection
Cited by 1,580
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HIF‐1α is required for solid tumor formation and embryonic vascularization
Ryan, H. E., Lo, J., & Johnson, R. S. (1998) · The EMBO Journal
Cancer, Hypoxia, and MetabolismAngiogenesis and VEGF in Cancer
Cited by 1,579
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Engineered AAVs for efficient noninvasive gene delivery to the central and peripheral nervous systems
Chan, K. Y., Jang, M. J., Yoo, B. B., Greenbaum, A., Ravi, N., Wu, W.-L., Sánchez-Guardado, L., Lois, C., Mazmanian, S. K., Deverman, B. E., et al. (2017) · Nature Neuroscience
Virus-based gene therapy researchRNA Interference and Gene Delivery
Cited by 1,578
- Verified
Expression profiling of mammalian microRNAs uncovers a subset of brain-expressed microRNAs with possible roles in murine and human neuronal differentiation
Sempere, L. F., Freemantle, S., Pitha-Rowe, I., Moss, E., Dmitrovsky, E., & Ambros, V. (2004) · Genome Biology
MicroRNA in disease regulationDevelopmental Biology and Gene Regulation
Cited by 1,578
- Verified
The packing of α-helices: simple coiled-coils
Crick, F. H. C. (1953) · Acta Crystallographica
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 1,578
- Verified
Molecular mechanism of PPARα action and its impact on lipid metabolism, inflammation and fibrosis in non-alcoholic fatty liver disease
Pawlak, M., Lefebvre, P., & Staels, B. (2015) · Journal of Hepatology
Peroxisome Proliferator-Activated ReceptorsLiver Disease Diagnosis and Treatment
Cited by 1,578
- Verified
Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel–Lindau protein
Ohh, M., Park, C. W., Ivan, M., Hoffman, M. A., Kim, T.-Y., Huang, L. E., Pavletich, N., Chau, V., & Kaelin, W. G. (2000) · Nature Cell Biology
Ubiquitin and proteasome pathwaysCancer, Hypoxia, and Metabolism
Cited by 1,577
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Tumor Microbiome Diversity and Composition Influence Pancreatic Cancer Outcomes
Riquelme, E., Zhang, Y., Zhang, L., Montiel, M., Zoltan, M., Dong, W., Quesada, P., Sahin, I., Chandra, V., San Lucas, A., et al. (2019) · Cell
Gut microbiota and healthPancreatic and Hepatic Oncology Research
Cited by 1,577
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High-Fat Diet Determines the Composition of the Murine Gut Microbiome Independently of Obesity
Hildebrandt, M. A., Hoffmann, C., Sherrill–Mix, S. A., Keilbaugh, S. A., Hamady, M., Chen, Y., Knight, R., Ahima, R. S., Bushman, F., & Wu, G. D. (2009) · Gastroenterology
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 1,576
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The return of metabolism: biochemistry and physiology of the pentose phosphate pathway
Stincone, A., Prigione, A., Cramer, T., Wamelink, M. M. C., Campbell, K., Cheung, E., Olin‐Sandoval, V., Grüning, N., Krüger, A., Tauqeer Alam, M., et al. (2015) · Biological Reviews
Biochemical and Molecular ResearchRedox biology and oxidative stress
Cited by 1,576
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