Most cited biochemistry, genetics and molecular biology papers
- Verified
Targeting of HIF-α to the von Hippel-Lindau Ubiquitylation Complex by O 2 -Regulated Prolyl Hydroxylation
Jaakkola, P., Mole, D. R., Tian, Y.-M., Wilson, M. I., Gielbert, J., Gaskell, S. J., Kriegsheim, A. V., Hebestreit, H. F., Mukherji, M., Schofield, C. J., et al. (2001) · Science
Cancer, Hypoxia, and MetabolismUbiquitin and proteasome pathways
Cited by 5,535
- Verified
Diversity, stability and resilience of the human gut microbiota
Lozupone, C. A., Stombaugh, J. I., Gordon, J. I., Jansson, J. K., & Knight, R. (2012) · Nature
Gut microbiota and healthOral microbiology and periodontitis research
Cited by 5,533
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Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy
Jain, R. K. (2005) · Science
Angiogenesis and VEGF in CancerMathematical Biology Tumor Growth
Cited by 5,527
- Verified
Evolutionary-scale prediction of atomic level protein structure with a language model
Lin, Z., Akin, H., Rao, R., Hie, B., Zhu, Z., Lu, W., Smetanin, N., Verkuil, R., Kabeli, O., Shmueli, Y., et al. (2022) · Science
Protein Structure and DynamicsMachine Learning in Bioinformatics
Cited by 5,523
- Verified
Profile hidden Markov models
Eddy, S. R. (1998) · Bioinformatics
Genomics and Phylogenetic StudiesMachine Learning in Bioinformatics
Cited by 5,515
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Toward understanding the origin and evolution of cellular organisms
Kanehisa, M. (2019) · Protein Science
Genomics and Phylogenetic StudiesBioinformatics and Genomic Networks
Cited by 5,509
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AQUA and PROCHECK-NMR: Programs for checking the quality of protein structures solved by NMR
Laskowski, R., Rullmann, J. A., MacArthur, M., Kaptein, R., & Thornton, J. (1996) · Journal of Biomolecular NMR
Protein Structure and DynamicsAdvanced NMR Techniques and Applications
Cited by 5,502
- Verified
The Inflammasomes
Schroder, K., & Tschopp, J. (2010) · Cell
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 5,475
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Molecular mechanisms and clinical applications of angiogenesis
Carmeliet, P., & Jain, R. K. (2011) · Nature
Angiogenesis and VEGF in CancerLymphatic System and Diseases
Cited by 5,467
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Regulation of microRNA biogenesis
Ha, M., & Kim, V. N. (2014) · Nature Reviews Molecular Cell Biology
MicroRNA in disease regulationRNA regulation and disease
Cited by 5,462
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Mutational heterogeneity in cancer and the search for new cancer-associated genes
Lawrence, M. S., Stojanov, P., Polak, P., Kryukov, G. V., Cibulskis, K., Sivachenko, A., Carter, S. L., Stewart, C., Mermel, C. H., Roberts, S. A., et al. (2013) · Nature
Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer
Cited by 5,461
- Verified
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
Trachootham, D., Alexandre, J., & Huang, P. (2009) · Nature Reviews Drug Discovery
Redox biology and oxidative stressCancer and biochemical research
Cited by 5,452
- Verified
RELION: Implementation of a Bayesian approach to cryo-EM structure determination
Scheres, S. H. W. (2012) · Journal of Structural Biology
Advanced Electron Microscopy Techniques and ApplicationsEnzyme Structure and Function
Cited by 5,446
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Stochastic Gene Expression in a Single Cell
Elowitz, M. B., Levine, A. J., Siggia, E. D., & Swain, P. S. (2002) · Science
Gene Regulatory Network Analysisstochastic dynamics and bifurcation
Cited by 5,441
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Oxidative stress, inflammation, and cancer: How are they linked?
Reuter, S., Gupta, S. C., Chaturvedi, M. M., & Aggarwal, B. B. (2010) · Free Radical Biology and Medicine
Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress
Cited by 5,441
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Base-Calling of Automated Sequencer Traces Using Phred. II. Error Probabilities
Ewing, B., & Green, P. (1998) · Genome Research
Genomics and Phylogenetic StudiesFractal and DNA sequence analysis
Cited by 5,439
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Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation.
Lacey, D. L., Timms, E., Tan, H.-L., Kelley, M. J., Dunstan, C. R., Burgess, T., Elliott, R., Colombero, A., Elliott, G., Scully, S., et al. (1998) · Cell
Bone Metabolism and DiseasesRheumatoid Arthritis Research and Therapies
Cited by 5,439
- Verified
DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139
Rogakou, E. P., Pilch, D. R., Orr, A. H., Ivanova, V. S., & Bonner, W. M. (1998) · Journal of Biological Chemistry
DNA Repair MechanismsEffects of Radiation Exposure
Cited by 5,438
- Verified
Programmable editing of a target base in genomic DNA without double-stranded DNA cleavage
Komor, A. C., Kim, Y. B., Packer, M. S., Zuris, J. A., & Liu, D. R. (2016) · Nature
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 5,437
- Verified
Revised Estimates for the Number of Human and Bacteria Cells in the Body
Sender, R., Fuchs, S., & Milo, R. (2016) · PLOS Biology
Gut microbiota and healthMicrobial Community Ecology and Physiology
Cited by 5,425
- Verified
The Microbial Metabolites, Short-Chain Fatty Acids, Regulate Colonic T reg Cell Homeostasis
Smith, P. M., Howitt, M. R., Panikov, N., Michaud, M., Gallini, C. A., Bohlooly-Y, M., Glickman, J. N., & Garrett, W. S. (2013) · Science
Gut microbiota and healthT-cell and B-cell Immunology
Cited by 5,413
- Verified
Comparison of the predicted and observed secondary structure of T4 phage lysozyme
Matthews, B. W. (1975) · Biochimica et Biophysica Acta (BBA) - Protein Structure
Protein Structure and DynamicsEnzyme Structure and Function
Cited by 5,399
- Verified
Role of the microbiota in immunity and inflammation.
Belkaid, Y., & Hand, T. W. (2014) · Cell
Gut microbiota and healthImmune Response and Inflammation
Cited by 5,385
- Verified
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
Zorov, D. B., Juhaszova, M., & Sollott, S. J. (2014) · Physiological Reviews
Mitochondrial Function and PathologyCell death mechanisms and regulation
Cited by 5,383
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