Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

Long non-coding RNAs: insights into functions

Mercer, T. R., Dinger, M. E., & Mattick, J. S. (2009) · Nature Reviews Genetics

Cancer-related molecular mechanisms researchRNA Research and Splicing

Cited by 5,654

Role of AMP-Activated Protein Kinase in Mechanism of Metformin Action

Zhou, G., Myers, R., Li, Y., Chen, Y., Shen, X., Fenyk-Melody, J., Wu, M., Ventre, J., Doebber, T., Fujii, N., et al. (2001) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerPeroxisome Proliferator-Activated Receptors

Cited by 5,652

The fundamental role of epigenetic events in cancer

Jones, P. A., & Baylin, S. B. (2002) · Nature Reviews Genetics

Epigenetics and DNA MethylationGenomics and Chromatin Dynamics

Cited by 5,648

Crystal Structure of Rhodopsin: A G Protein-Coupled Receptor

Palczewski, K., Kumasaka, T., Hori, T., Behnke, C. A., Motoshima, H., Fox, B. A., Trong, I. L., Teller, D. C., Okada, T., Stenkamp, R. E., et al. (2000) · Science

Receptor Mechanisms and SignalingPhotoreceptor and optogenetics research

Cited by 5,637

Dictionary learning for integrative, multimodal and scalable single-cell analysis

Hao, Y., Stuart, T., Kowalski, M. H., Choudhary, S., Hoffman, P., Hartman, A., Srivastava, A., Molla, G., Madad, S., Fernandez-Granda, C., et al. (2024) · Nature Biotechnology

Single-cell and spatial transcriptomicsBioinformatics and Genomic Networks

Cited by 5,631

The phosphoinositide 3-kinase pathway

Cantley, L. C. (2002) · Science

PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer

Cited by 5,621

The Endophenotype Concept in Psychiatry: Etymology and Strategic Intentions

Gottesman, I. I., & Gould, T. D. (2003) · American Journal of Psychiatry

Genetic Associations and EpidemiologyMental Health and Psychiatry

Cited by 5,615

A role for mitochondria in nlrp3 inflammasome activation

Zhou, R., Yazdi, A. S., Menu, P., & Tschopp, J. (2011) · Nature

Inflammasome and immune disordersImmune Response and Inflammation

Cited by 5,602

FastTree: Computing Large Minimum Evolution Trees with Profiles instead of a Distance Matrix

Price, M. N., Dehal, P. S., & Arkin, A. P. (2009) · Molecular Biology and Evolution

Genomics and Phylogenetic StudiesRNA and protein synthesis mechanisms

Cited by 5,602

Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease

Wang, Z., Klipfell, E., Bennett, B. J., Koeth, R., Levison, B. S., DuGar, B., Feldstein, A. E., Britt, E. B., Fu, X., Chung, Y.-M., et al. (2011) · Nature

Gut microbiota and healthMetabolomics and Mass Spectrometry Studies

Cited by 5,597

Identification of human triple-negative breast cancer subtypes and preclinical models for selection of targeted therapies

Lehmann, B. D., Bauer, J. A., Chen, X., Sanders, M. E., Chakravarthy, A. B., Shyr, Y., & Pietenpol, J. A. (2011) · Journal of Clinical Investigation

Breast Cancer Treatment StudiesBreast Lesions and Carcinomas

Cited by 5,592

Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease

Hugot, J.-P., Chamaillard, M., Zouali, H., Lesage, S., Cézard, J.-P., Belaiche, J., Almer, S., Tysk, C., O'Morain, C. A., Gassull, M., et al. (2001) · Nature

Inflammatory Bowel DiseaseImmune Response and Inflammation

Cited by 5,591

Pathogenic Escherichia coli

Kaper, J. B., Nataro, J. P., & Mobley, H. L. T. (2004) · Nature Reviews Microbiology

Escherichia coli research studiesBacterial Genetics and Biotechnology

Cited by 5,583

Wnt/β-Catenin Signaling: Components, Mechanisms, and Diseases

MacDonald, B. T., Tamai, K., & He, X. (2009) · Developmental Cell

Wnt/β-catenin signaling in development and cancerSignaling Pathways in Disease

Cited by 5,583

Impact of diet in shaping gut microbiota revealed by a comparative study in children from Europe and rural Africa

De Filippo, C., Cavalieri, D., Di Paola, M., Ramazzotti, M., Poullet, J. B., Massart, S., Collini, S., Pieraccini, G., & Lionetti, P. (2010) · Proceedings of the National Academy of Sciences

Gut microbiota and healthInfant Nutrition and Health

Cited by 5,579

Genome-wide atlas of gene expression in the adult mouse brain

Lein, E. S., Hawrylycz, M. J., Ao, N., Ayres, M., Bensinger, A., Bernard, A., Boe, A. F., Boguski, M. S., Brockway, K. S., Byrnes, E. J., et al. (2007) · Nature

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 5,572

Wnt/β-Catenin Signaling in Development and Disease

Clevers, H. (2006) · Cell

Wnt/β-catenin signaling in development and cancerDevelopmental Biology and Gene Regulation

Cited by 5,568

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

Schizophrenia Working Group of the Psychiatric Genomics Consortium, Bulik-Sullivan, B. K., Loh, P.-R., Finucane, H. K., Ripke, S., Yang, J., Patterson, N., Daly, M. J., Price, A. L., & Neale, B. M. (2015) · Nature Genetics

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 5,559

Wnt/β-catenin signaling and disease

Clevers, H., & Nusse, R. (2012) · Cell

Wnt/β-catenin signaling in development and cancerSignaling Pathways in Disease

Cited by 5,554

The GeneCards suite: from gene data mining to disease genome sequence analyses

Stelzer, G., Rosen, N., Plaschkes, I., Zimmerman, S., Twik, M., Fishilevich, S., Stein, T. I., Nudel, R., Lieder, I., Mazor, Y., et al. (2016) · Current Protocols in Bioinformatics

Genomics and Rare DiseasesBioinformatics and Genomic Networks

Cited by 5,550

Commensal microbe-derived butyrate induces the differentiation of colonic regulatory T cells

Furusawa, Y., Obata, Y., Fukuda, S., Endo, T. A., Nakato, G., Takahashi, D., Nakanishi, Y., Uetake, C., Kato, K., Kato, T., et al. (2013) · Nature

Gut microbiota and healthT-cell and B-cell Immunology

Cited by 5,549

The GTEx Consortium atlas of genetic regulatory effects across human tissues

The GTEx Consortium, Aguet, F., Anand, S., Ardlie, K. G., Gabriel, S., Getz, G. A., Graubert, A., Hadley, K., Handsaker, R. E., Huang, K. H., et al. (2020) · Science

Genetic Associations and EpidemiologyRNA Research and Splicing

Cited by 5,547

Bioavailability of curcumin: Problems and promises

Anand, P., Kunnumakkara, A. B., Newman, R. A., & Aggarwal, B. B. (2007) · Molecular Pharmaceutics

Curcumin's Biomedical ApplicationsDrug Solubulity and Delivery Systems

Cited by 5,543

Accurate prediction of protein structures and interactions using a 3-track network

Baek, M., DiMaio, F., Anishchenko, I., Dauparas, J., Ovchinnikov, S., Lee, G. R., Wang, J., Cong, Q., Kinch, L. N., Schaeffer, R. D., et al. (2021) · Science

Protein Structure and DynamicsMachine Learning in Bioinformatics

Cited by 5,542