Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

In vivo genome editing improves muscle function in a mouse model of Duchenne muscular dystrophy

Nelson, C. E., Hakim, C. H., Ousterout, D. G., Thakore, P. I., Moreb, E. A., Rivera, R. M. C., Madhavan, S., Pan, X., Ran, F. A., Yan, W. X., et al. (2016) · Science

CRISPR and Genetic EngineeringMuscle Physiology and Disorders

Cited by 1,144

Mutation rates among RNA viruses

Drake, J. W., & Holland, J. J. (1999) · Proceedings of the National Academy of Sciences

Evolution and Genetic DynamicsRNA and protein synthesis mechanisms

Cited by 1,143

A data-driven approach to preprocessing Illumina 450K methylation array data

Pidsley, R., Y Wong, C. C., Volta, M., Lunnon, K., Mill, J., & Schalkwyk, L. C. (2013) · BMC Genomics

Epigenetics and DNA MethylationGene expression and cancer classification

Cited by 1,143

PPAR-γ is a major driver of the accumulation and phenotype of adipose tissue Treg cells

Cipolletta, D., Feuerer, M., Li, A., Kamei, N., Lee, J., Shoelson, S. E., Benoist, C., & Mathis, D. (2012) · Nature

Peroxisome Proliferator-Activated ReceptorsAdipokines, Inflammation, and Metabolic Diseases

Cited by 1,143

Epigenetic stem cell signature in cancer

Widschwendter, M., Fiegl, H., Egle, D., Mueller-Holzner, E., Spizzo, G., Marth, C., Weisenberger, D. J., Campan, M., Young, J., Jacobs, I., et al. (2007) · Nature Genetics

Epigenetics and DNA MethylationCancer Cells and Metastasis

Cited by 1,143

Trehalose, a Novel mTOR-independent Autophagy Enhancer, Accelerates the Clearance of Mutant Huntingtin and α-Synuclein

Sarkar, S., Davies, J. E., Huang, Z., Tunnacliffe, A., & Rubinsztein, D. C. (2007) · Journal of Biological Chemistry

Autophagy in Disease and TherapyGenetic Neurodegenerative Diseases

Cited by 1,142

How significant is a protein structure similarity with TM-score = 0.5?

Xu, J., & Zhang, Y. (2010) · Bioinformatics

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 1,142

Extracellular Matrix in the Tumor Microenvironment and Its Impact on Cancer Therapy

Henke, E., Nandigama, R., & Ergün, S. (2020) · Frontiers in Molecular Biosciences

Cellular Mechanics and InteractionsCancer Cells and Metastasis

Cited by 1,142

Overview of Structure and Function of Mammalian Cilia

Satir, P., & Christensen, S. T. (2007) · Annual Review of Physiology

Genetic and Kidney Cyst DiseasesCystic Fibrosis Research Advances

Cited by 1,142

Oxygen radicals, nitric oxide, and peroxynitrite: Redox pathways in molecular medicine

Radi, R. (2018) · Proceedings of the National Academy of Sciences

Redox biology and oxidative stressNitric Oxide and Endothelin Effects

Cited by 1,142

Cellular Memory and the Histone Code

Turner, B. M. (2002) · Cell

Genomics and Chromatin DynamicsEpigenetics and DNA Methylation

Cited by 1,142

Keap1-dependent proteasomal degradation of transcription factor Nrf2 contributes to the negative regulation of antioxidant response element-driven gene expression

McMahon, M., Itoh, K., Yamamoto, M., & Hayes, J. D. (2003) · Journal of Biological Chemistry

Genomics, phytochemicals, and oxidative stressRedox biology and oxidative stress

Cited by 1,141

A Global Map of p53 Transcription-Factor Binding Sites in the Human Genome

Wei, C.-L., Wu, Q., Vega, V. B., Chiu, K. P., Ng, P., Zhang, T., Shahab, A., Yong, H. C., Fu, Y., Weng, Z., et al. (2006) · Cell

Genomics and Chromatin DynamicsCancer-related Molecular Pathways

Cited by 1,141

Structure of the DDB1–CRBN E3 ubiquitin ligase in complex with thalidomide

Fischer, E. S., Böhm, K., Lydeard, J. R., Yang, H., Stadler, M. B., Cavadini, S., Nagel, J., Serluca, F., Acker, V., Lingaraju, G. M., et al. (2014) · Nature

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 1,141

Programmed Cell Death 4 (PDCD4) Is an Important Functional Target of the MicroRNA miR-21 in Breast Cancer Cells

Frankel, L. B., Christoffersen, N. R., Jacobsen, A., Lindow, M., Krogh, A., & Lund, A. H. (2008) · Journal of Biological Chemistry

MicroRNA in disease regulationCancer-related molecular mechanisms research

Cited by 1,141

Identification of 64 novel genetic loci provides an expanded view on the genetic architecture of coronary artery disease

van der Harst, P., & Verweij, N. (2018) · Circulation Research

Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals

Cited by 1,141

MicroRNA Expression Patterns to Differentiate Pancreatic Adenocarcinoma From Normal Pancreas and Chronic Pancreatitis

Bloomston, M., Frankel, W. L., Petrocca, F., Volinia, S., Alder, H., Hagan, J. P., Liu, C.-G., Bhatt, D., Taccioli, C., & Croce, C. M. (2007) · JAMA

MicroRNA in disease regulationPancreatic and Hepatic Oncology Research

Cited by 1,141

Multivalent N -Acetylgalactosamine-Conjugated siRNA Localizes in Hepatocytes and Elicits Robust RNAi-Mediated Gene Silencing

Nair, J. K., Willoughby, J. L. S., Chan, A., Charisse, K., Alam, M. R., Wang, Q., Hoekstra, M., Kandasamy, P., Kel’in, A. V., Milstein, S., et al. (2014) · Journal of the American Chemical Society

RNA Interference and Gene DeliveryDNA and Nucleic Acid Chemistry

Cited by 1,141

Thermodynamic parameters for an expanded nearest-neighbor model for formation of RNA duplexes with Watson–Crick base pairs

Xia, T., SantaLucia, J., Burkard, M. E., Kierzek, R., Schroeder, S. J., Jiao, X., Cox, C., & Turner, D. H. (1998) · Biochemistry

RNA and protein synthesis mechanismsDNA and Nucleic Acid Chemistry

Cited by 1,140

Hijacking the E3 Ubiquitin Ligase Cereblon to Efficiently Target BRD4

Lu, J., Qian, Y., Altieri, M., Dong, H., Wang, J., Raina, K., Hines, J., Winkler, J. D., Crew, A. P., Coleman, K., et al. (2015) · Chemistry & Biology

Protein Degradation and InhibitorsUbiquitin and proteasome pathways

Cited by 1,140

Lamina-Associated Domains: Links with Chromosome Architecture, Heterochromatin, and Gene Repression

van Steensel, B., & Belmont, A. S. (2017) · Cell

Nuclear Structure and FunctionGenomics and Chromatin Dynamics

Cited by 1,140

Pharmacological basis for the role of curcumin in chronic diseases: an age-old spice with modern targets

Aggarwal, B. B., & Sung, B. (2009) · Trends in Pharmacological Sciences

Curcumin's Biomedical ApplicationsSaffron Plant Research Studies

Cited by 1,140

Autophagy in Human Diseases

Mizushima, N., & Levine, B. (2020) · New England Journal of Medicine

Autophagy in Disease and TherapyUbiquitin and proteasome pathways

Cited by 1,140

Hypoxia, DNA repair and genetic instability

Bristow, R. G., & Hill, R. P. (2008) · Nature Reviews Cancer

Cancer, Hypoxia, and MetabolismDNA Repair Mechanisms

Cited by 1,140