Check biochemistry, genetics and molecular biology papers: citations, claims and retractions

From noncoding variant to phenotype via SORT1 at the 1p13 cholesterol locus

Musunuru, K., Strong, A., Frank-Kamenetsky, M., Lee, N. E., Ahfeldt, T., Sachs, K. V., Li, X., Li, H., Kuperwasser, N., Ruda, V. M., et al. (2010) · Nature

Genetic Associations and EpidemiologyCholesterol and Lipid Metabolism

Cited by 1,140

Mapping copy number variation by population-scale genome sequencing

1000 Genomes Project, Mills, R. E., Walter, K., Stewart, C., Handsaker, R. E., Chen, K., Alkan, C., Abyzov, A., Yoon, S. C., Ye, K., et al. (2011) · Nature

Genomic variations and chromosomal abnormalitiesGenome Rearrangement Algorithms

Cited by 1,140

Overcoming cellular barriers for RNA therapeutics

Dowdy, S. F. (2017) · Nature Biotechnology

RNA Interference and Gene DeliveryNanoparticle-Based Drug Delivery

Cited by 1,139

Human L1 retrotransposon encodes a conserved endonuclease required for retrotransposition

Feng, Q., Moran, J. V., Kazazian, H. H., & Boeke, J. D. (1996) · Cell

Chromosomal and Genetic VariationsGenomic variations and chromosomal abnormalities

Cited by 1,139

Insulin resistance differentially affects the PI 3-kinase- and MAP kinase-mediated signaling in human muscle

Cusi, K., Maezono, K., Osman, A., Pendergrass, M., Patti, M. E., Pratipanawatr, T., DeFronzo, R. A., Kahn, C. R., & Mandarino, L. J. (2000) · Journal of Clinical Investigation

Metabolism, Diabetes, and CancerDiabetes, Cardiovascular Risks, and Lipoproteins

Cited by 1,139

Telomere loss: mitotic clock or genetic time bomb?

Harley, C. B. (1991) · Mutation Research/DNAging

Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms

Cited by 1,139

HiChIP: efficient and sensitive analysis of protein-directed genome architecture

Mumbach, M. R., Rubin, A. J., Flynn, R. A., Dai, C., Khavari, P. A., Greenleaf, W. J., & Chang, H. Y. (2016) · Nature Methods

Genomics and Chromatin DynamicsChromatin Remodeling and Cancer

Cited by 1,139

Moving pictures of the human microbiome

Caporaso, J. G., Lauber, C. L., Costello, E. K., Berg-Lyons, D., Gonzalez, A., Stombaugh, J., Knights, D., Gajer, P., Ravel, J., Fierer, N., et al. (2011) · Genome Biology

Gut microbiota and healthMicrobial Community Ecology and Physiology

Cited by 1,138

lDDT: a local superposition-free score for comparing protein structures and models using distance difference tests

Mariani, V., Biasini, M., Barbato, A., & Schwede, T. (2013) · Bioinformatics

Protein Structure and DynamicsEnzyme Structure and Function

Cited by 1,138

Enterotypes in the landscape of gut microbial community composition

Costea, P. I., Hildebrand, F., Arumugam, M., Bäckhed, F., Blaser, M. J., Bushman, F. D., de Vos, W. M., Ehrlich, S. D., Fraser, C. M., Hattori, M., et al. (2017) · Nature Microbiology

Gut microbiota and healthMicrobial Community Ecology and Physiology

Cited by 1,138

Landscape of X chromosome inactivation across human tissues

GTEx Consortium, Tukiainen, T., Villani, A.-C., Yen, A., Rivas, M. A., Marshall, J. L., Satija, R., Aguirre, M., Gauthier, L., Fleharty, M., et al. (2017) · Nature

Genetic and Clinical Aspects of Sex Determination and Chromosomal AbnormalitiesGenomics and Chromatin Dynamics

Cited by 1,138

Metabolic heterogeneity in human lung tumors

Hensley, C. T., Faubert, B., Yuan, Q., Lev-Cohain, N., Jin, E., Kim, J., Jiang, L., Ko, B., Skelton, R., Loudat, L., et al. (2016) · Cell

Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer

Cited by 1,138

Molecular Motors in Neurons: Transport Mechanisms and Roles in Brain Function, Development, and Disease

Hirokawa, N., Niwa, S., & Tanaka, Y. (2010) · Neuron

Microtubule and mitosis dynamicsNeuroscience and Neuropharmacology Research

Cited by 1,138

Whole-genome resequencing reveals loci under selection during chicken domestication

Rubin, C.-J., Zody, M. C., Eriksson, J., Meadows, J. R. S., Sherwood, E., Webster, M. T., Jiang, L., Ingman, M., Sharpe, T., Ka, S., et al. (2010) · Nature

Genetic and phenotypic traits in livestockLivestock and Poultry Management

Cited by 1,138

A polyphenol-rich cranberry extract protects from diet-induced obesity, insulin resistance and intestinal inflammation in association with increased Akkermansia spp. population in the gut microbiota of mice

Anhê, F. F., Roy, D., Pilon, G., Dudonné, S., Matamoros, S., Varin, T. V., Garofalo, C., Moine, Q., Desjardins, Y., Levy, E., et al. (2015) · Gut

Gut microbiota and healthNatural Antidiabetic Agents Studies

Cited by 1,137

Design principles of biochemical oscillators

Novák, B., & Tyson, J. J. (2008) · Nature Reviews Molecular Cell Biology

Gene Regulatory Network AnalysisCircadian rhythm and melatonin

Cited by 1,137

Genetic Structure and Diversity in Oryza sativa L.

Garris, A. J., Tai, T. H., Coburn, J., Kresovich, S., & McCouch, S. (2005) · Genetics

Genetic Mapping and Diversity in Plants and AnimalsGenetic diversity and population structure

Cited by 1,137

Localized Igf-1 transgene expression sustains hypertrophy and regeneration in senescent skeletal muscle

Musarò, A., McCullagh, K., Paul, A., Houghton, L., Dobrowolny, G., Molinaro, M., Barton, E. R., L Sweeney, H., & Rosenthal, N. (2001) · Nature Genetics

Muscle Physiology and DisordersNeurogenetic and Muscular Disorders Research

Cited by 1,137

R-2HG Exhibits Anti-tumor Activity by Targeting FTO/m6A/MYC/CEBPA Signaling

Su, R., Dong, L., Li, C., Nachtergaele, S., Wunderlich, M., Qing, Y., Deng, X., Wang, Y., Weng, X., Hu, C., et al. (2018) · Cell

RNA modifications and cancerAcute Myeloid Leukemia Research

Cited by 1,137

Molecularly targeted therapy based on tumour molecular profiling versus conventional therapy for advanced cancer (SHIVA): a multicentre, open-label, proof-of-concept, randomised, controlled phase 2 trial

Le Tourneau, C., Delord, J.-P., Gonçalves, A., Gavoille, C., Dubot, C., Isambert, N., Campone, M., Trédan, O., Massiani, M.-A., Mauborgne, C., et al. (2015) · The Lancet Oncology

Cancer Genomics and DiagnosticsLung Cancer Treatments and Mutations

Cited by 1,137

Increasing the efficiency of precise genome editing with CRISPR-Cas9 by inhibition of nonhomologous end joining

Maruyama, T., Dougan, S. K., Truttmann, M. C., Bilate, A. M., Ingram, J. R., & Ploegh, H. L. (2015) · Nature Biotechnology

CRISPR and Genetic EngineeringDNA Repair Mechanisms

Cited by 1,137

Epithelial-cell recognition of commensal bacteria and maintenance of immune homeostasis in the gut

Artis, D. (2008) · Nature reviews. Immunology

Gut microbiota and healthImmune Response and Inflammation

Cited by 1,136

Computational analysis of cell-to-cell heterogeneity in single-cell RNA-sequencing data reveals hidden subpopulations of cells

Buettner, F., Natarajan, K. N., Casale, F. P., Proserpio, V., Scialdone, A., Theis, F. J., Teichmann, S. A., Marioni, J. C., & Stegle, O. (2015) · Nature Biotechnology

Single-cell and spatial transcriptomicsGene expression and cancer classification

Cited by 1,136

Uncovering the roles of rare variants in common disease through whole-genome sequencing

Cirulli, E. T., & Goldstein, D. B. (2010) · Nature Reviews Genetics

Genetic Associations and EpidemiologyGenomics and Rare Diseases

Cited by 1,136