Most cited biochemistry, genetics and molecular biology papers
- Verified
ChEA3: transcription factor enrichment analysis by orthogonal omics integration
Keenan, A. B., Torre, D., Lachmann, A., Leong, A. K., Wojciechowicz, M. L., Utti, V., Jagodnik, K. M., Kropiwnicki, E., Wang, Z., & Ma’ayan, A. (2019) · Nucleic Acids Research
Bioinformatics and Genomic NetworksGenomics and Chromatin Dynamics
Cited by 1,136
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Homologous Recombination Deficiency (HRD) Score Predicts Response to Platinum-Containing Neoadjuvant Chemotherapy in Patients with Triple-Negative Breast Cancer
Telli, M. L., Timms, K. M., Reid, J., Hennessy, B., Mills, G. B., Jensen, K. C., Szallasi, Z., Barry, W. T., Winer, E. P., Tung, N. M., et al. (2016) · Clinical Cancer Research
BRCA gene mutations in cancerBreast Cancer Treatment Studies
Cited by 1,136
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Exercise-induced BCL2-regulated autophagy is required for muscle glucose homeostasis
He, C., Bassik, M. C., Moresi, V., Sun, K., Wei, Y., Zou, Z., An, Z., Loh, J., Fisher, J., Sun, Q., et al. (2012) · Nature
Autophagy in Disease and TherapyMetabolism, Diabetes, and Cancer
Cited by 1,136
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Cell Wall Integrity Signaling in Saccharomyces cerevisiae
Levin, D. E. (2005) · Microbiology and Molecular Biology Reviews
Fungal and yeast genetics researchBacterial Genetics and Biotechnology
Cited by 1,136
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Cellular adaptation to hypoxia: O 2 ‐sensing protein hydroxylases, hypoxia‐inducible transcription factors, and O 2 ‐regulated gene expression
Wenger, R. H. (2002) · The FASEB Journal
Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment
Cited by 1,135
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Muscle strength and speed of movement in relation to age and muscle morphology
Larsson, L., Grimby, G., & Karlsson, J. (1979) · Journal of Applied Physiology
Muscle Physiology and DisordersNutrition and Health in Aging
Cited by 1,135
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CRISPR/Cas9-mediated gene editing in human tripronuclear zygotes
Liang, P., Xu, Y., Zhang, X., Ding, C., Huang, R., Zhang, Z., Lv, J., Xie, X., Chen, Y., Li, Y., et al. (2015) · Protein & Cell
CRISPR and Genetic EngineeringAnimal Genetics and Reproduction
Cited by 1,135
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DIANA-TarBase v8: a decade-long collection of experimentally supported miRNA–gene interactions
Karagkouni, D., Paraskevopoulou, M. D., Chatzopoulos, S., Vlachos, I. S., Tastsoglou, S., Kanellos, I., Papadimitriou, D., Kavakiotis, I., Maniou, S., Skoufos, G., et al. (2018) · Nucleic Acids Research
MicroRNA in disease regulationCancer-related molecular mechanisms research
Cited by 1,135
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Pedigree disequilibrium tests for multilocus haplotypes.
Dudbridge, F. (2003) · Genetic Epidemiology
Genetic Associations and EpidemiologyForensic and Genetic Research
Cited by 1,135
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Suppression of Antitumor Immunity by Stromal Cells Expressing Fibroblast Activation Protein–α
Kraman, M., Bambrough, P. J., Arnold, J. N., Roberts, E. W., Magiera, L., Jones, J. O., Gopinathan, A., Tuveson, D. A., & Fearon, D. T. (2010) · Science
Peptidase Inhibition and AnalysisImmune cells in cancer
Cited by 1,134
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Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors
Wilson, T. R., Fridlyand, J., Yan, Y., Penuel, E., Burton, L., Chan, E., Peng, J., Lin, E., Wang, Y., Sosman, J., et al. (2012) · Nature
Melanoma and MAPK PathwaysLung Cancer Treatments and Mutations
Cited by 1,134
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Cellular senescence and senolytics: the path to the clinic
Chaib, S., Tchkonia, T., & Kirkland, J. L. (2022) · Nature Medicine
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,134
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Autophagy and Neurodegeneration: Pathogenic Mechanisms and Therapeutic Opportunities
Menzies, F. M., Fleming, A., Caricasole, A., Bento, C. F., Andrews, S. P., Ashkenazi, A., Füllgrabe, J., Jackson, A., Jimenez Sanchez, M., Karabiyik, C., et al. (2017) · Neuron
Autophagy in Disease and TherapyAlzheimer's disease research and treatments
Cited by 1,134
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Identification and characterization of NVP-BEZ235, a new orally available dual phosphatidylinositol 3-kinase/mammalian target of rapamycin inhibitor with potent in vivo antitumor activity
Maira, S.-M., Stauffer, F., Brueggen, J., Furet, P., Schnell, C., Fritsch, C., Brachmann, S., Chène, P., De Pover, A., Schoemaker, K., et al. (2008) · Molecular Cancer Therapeutics
PI3K/AKT/mTOR signaling in cancerMetabolism, Diabetes, and Cancer
Cited by 1,134
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Cancer-associated adipocytes exhibit an activated phenotype and contribute to breast cancer invasion
Dirat, B., Bochet, L., Dabek, M., Daviaud, D., Dauvillier, S., Majed, B., Wang, Y. Y., Meulle, A., Salles, B., Le Gonidec, S., et al. (2011) · Cancer Research
Cancer, Lipids, and MetabolismImmune cells in cancer
Cited by 1,134
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Long-term ecological impacts of antibiotic administration on the human intestinal microbiota
Jernberg, C., Löfmark, S., Edlund, C., & Jansson, J. K. (2007) · The ISME Journal
Gut microbiota and healthMicrobial Community Ecology and Physiology
Cited by 1,134
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A translational profiling approach for the molecular characterization of CNS cell types
Heiman, M., Schaefer, A., Gong, S., Peterson, J. D., Day, M., Ramsey, K. E., Suárez-Fariñas, M., Schwarz, C., Stephan, D. A., Surmeier, D. J., et al. (2008) · Cell
RNA and protein synthesis mechanismsNeuroscience and Neuropharmacology Research
Cited by 1,134
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A Fine-Scale Map of Recombination Rates and Hotspots Across the Human Genome
Myers, S., Bottolo, L., Freeman, C., McVean, G., & Donnelly, P. (2005) · Science
Genetic Associations and EpidemiologyChromosomal and Genetic Variations
Cited by 1,134
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Proteolysis: from the lysosome to ubiquitin and the proteasome
Ciechanover, A. (2005) · Nature Reviews Molecular Cell Biology
Ubiquitin and proteasome pathwaysAutophagy in Disease and Therapy
Cited by 1,133
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EEA1 links PI(3)K function to Rab5 regulation of endosome fusion
Simonsen, A., Lippe, R., Christoforidis, S., Gaullier, J.-M., Brech, A., Callaghan, J., Toh, B.-H., Murphy, C., Zerial, M., & Stenmark, H. (1998) · Nature
Cellular transport and secretionCalcium signaling and nucleotide metabolism
Cited by 1,133
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Reactive oxygen species: from health to disease
Brieger, K., Schiavone, S., Miller Jr., F. J., & Krause, K.-H. (2012) · Swiss Medical Weekly
Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress
Cited by 1,133
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Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.
Vaziri, H., Dragowska, W., Allsopp, R. C., Thomas, T. E., Harley, C. B., & Lansdorp, P. M. (1994) · Proceedings of the National Academy of Sciences
Telomeres, Telomerase, and SenescenceHematopoietic Stem Cell Transplantation
Cited by 1,132
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Gene–environment interactions in human diseases
Hunter, D. J. (2005) · Nature Reviews Genetics
Genetic Associations and EpidemiologyHealth, Environment, Cognitive Aging
Cited by 1,132
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[6] Correction for liquid junction potentials in patch clamp experiments
Neher, E. (1992) · Methods in Enzymology
Ion channel regulation and functionElectrochemical Analysis and Applications
Cited by 1,132
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