Most cited biochemistry, genetics and molecular biology papers
- Verified
Cytoplasmic flagellin activates caspase-1 and secretion of interleukin 1β via Ipaf
Miao, E. A., Alpuche-Aranda, C. M., Dors, M., Clark, A. E., Bader, M. W., Miller, S. I., & Aderem, A. (2006) · Nature Immunology
Inflammasome and immune disordersImmune Response and Inflammation
Cited by 1,127
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KRAS Mutation: From Undruggable to Druggable in Cancer
Huang, L., Guo, Z., Wang, F., & Fu, L. (2021) · Signal Transduction and Targeted Therapy
Protein Kinase Regulation and GTPase SignalingMelanoma and MAPK Pathways
Cited by 1,127
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The temperature response of C 3 and C 4 photosynthesis
SAGE, R. F., & KUBIEN, D. S. (2007) · Plant, Cell & Environment
Photosynthetic Processes and MechanismsPlant Water Relations and Carbon Dynamics
Cited by 1,127
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Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase
Wu, Y.-T., Tan, H.-L., Shui, G., Bauvy, C., Huang, Q., Wenk, M. R., Ong, C.-N., Codogno, P., & Shen, H.-M. (2010) · Journal of Biological Chemistry
Autophagy in Disease and TherapyCellular transport and secretion
Cited by 1,127
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Heme Oxygenase-1: Function, Regulation, and Implication of a Novel Stress-Inducible Protein in Oxidant-Induced Lung Injury
Choi, A. M., & Alam, J. (1996) · American Journal of Respiratory Cell and Molecular Biology
Heme Oxygenase-1 and Carbon MonoxideHemoglobin structure and function
Cited by 1,126
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iCLIP reveals the function of hnRNP particles in splicing at individual nucleotide resolution
König, J., Zarnack, K., Rot, G., Curk, T., Kayikci, M., Zupan, B., Turner, D. J., Luscombe, N. M., & Ule, J. (2010) · Nature Structural & Molecular Biology
RNA Research and SplicingRNA regulation and disease
Cited by 1,126
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A General Test of Association for Quantitative Traits in Nuclear Families
Abecasis, G. R., Cardon, L. R., & Cookson, W. O. C. (2000) · The American Journal of Human Genetics
Genetic Associations and EpidemiologyGenetic Mapping and Diversity in Plants and Animals
Cited by 1,126
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Synchronized renal tubular cell death involves ferroptosis
Linkermann, A., Skouta, R., Himmerkus, N., Mulay, S. R., Dewitz, C., De Zen, F., Prokai, A., Zuchtriegel, G., Krombach, F., Welz, P.-S., et al. (2014) · Proceedings of the National Academy of Sciences
Ferroptosis and cancer prognosisCell death mechanisms and regulation
Cited by 1,126
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The promise and challenge of therapeutic genome editing
Doudna, J. A. (2020) · Nature
CRISPR and Genetic EngineeringRNA regulation and disease
Cited by 1,126
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DNA methylation-based measures of biological age: meta-analysis predicting time to death
Chen, B. H., Marioni, R. E., Colicino, E., Peters, M. J., Ward-Caviness, C. K., Tsai, P.-C., Roetker, N. S., Just, A. C., Demerath, E. W., Guan, W., et al. (2016) · Aging
Epigenetics and DNA MethylationGenetics, Aging, and Longevity in Model Organisms
Cited by 1,126
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Horizontal gene transfer in prokaryotes: Quantification and classification
Koonin, E. V., Makarova, K. S., & Aravind, L. (2001) · Annual Review of Microbiology
Genomics and Phylogenetic StudiesBacterial Genetics and Biotechnology
Cited by 1,126
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Role of a peptide tagging system in degradation of proteins synthesized from damaged messenger RNA
Keiler, K. C., Waller, P. R. H., & Sauer, R. T. (1996) · Science
RNA and protein synthesis mechanismsBacterial Genetics and Biotechnology
Cited by 1,125
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Genome-Wide Quantitative Enhancer Activity Maps Identified by STARR-seq
Arnold, C. D., Gerlach, D., Stelzer, C., Boryń, Ł. M., Rath, M., & Stark, A. (2013) · Science
Genomics and Chromatin DynamicsChromatin Remodeling and Cancer
Cited by 1,125
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Efficient in vivo manipulation of mouse genomic sequences at the zygote stage.
Lakso, M., Pichel, J. G., Gorman, J. R., Sauer, B., Okamoto, Y., Lee, E., Alt, F. W., & Westphal, H. (1996) · Proceedings of the National Academy of Sciences
Animal Genetics and ReproductionCRISPR and Genetic Engineering
Cited by 1,125
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Single-cell genome-wide bisulfite sequencing for assessing epigenetic heterogeneity
Smallwood, S. A., Lee, H. J., Angermueller, C., Krueger, F., Saadeh, H., Peat, J., Andrews, S. R., Stegle, O., Reik, W., & Kelsey, G. (2014) · Nature Methods
Epigenetics and DNA MethylationSingle-cell and spatial transcriptomics
Cited by 1,125
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CEL-seq2: sensitive highly-multiplexed single-cell RNA-Seq
Hashimshony, T., Senderovich, N., Avital, G., Klochendler, A., de Leeuw, Y., Anavy, L., Gennert, D., Li, S., Livak, K. J., Rozenblatt-Rosen, O., et al. (2016) · Genome Biology
Single-cell and spatial transcriptomicsGenomics and Phylogenetic Studies
Cited by 1,125
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Fatty acid biosynthesis in microorganisms being used for Single Cell Oil production
Ratledge, C. (2004) · Biochimie
Lipid metabolism and biosynthesisMicrobial Metabolic Engineering and Bioproduction
Cited by 1,125
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Genome sequencing identifies major causes of severe intellectual disability
Gilissen, C., Hehir-Kwa, J. Y., Thung, D. T., van de Vorst, M., van Bon, B. W. M., Willemsen, M. H., Kwint, M., Janssen, I. M., Hoischen, A., Schenck, A., et al. (2014) · Nature
Genomics and Rare DiseasesGenomic variations and chromosomal abnormalities
Cited by 1,125
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Epigenetic transmission of the impact of early stress across generations
Franklin, T. B., Russig, H., Weiss, I. C., Gräff, J., Linder, N., Michalon, A., Vizi, S., & Mansuy, I. M. (2010) · Biological Psychiatry
Epigenetics and DNA MethylationStress Responses and Cortisol
Cited by 1,125
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Short-Chain Fatty Acids Protect Against High-Fat Diet–Induced Obesity via a PPARγ-Dependent Switch From Lipogenesis to Fat Oxidation
den Besten, G., Bleeker, A., Gerding, A., van Eunen, K., Havinga, R., van Dijk, T. H., Oosterveer, M. H., Jonker, J. W., Groen, A. K., Reijngoud, D.-J., et al. (2015) · Diabetes
Peroxisome Proliferator-Activated ReceptorsGut microbiota and health
Cited by 1,125
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Senescence in tumours: evidence from mice and humans
Collado, M., & Serrano, M. (2010) · Nature Reviews Cancer
Telomeres, Telomerase, and SenescenceGenetics, Aging, and Longevity in Model Organisms
Cited by 1,124
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The influence of glucose-lowering therapies on cancer risk in type 2 diabetes
Currie, C. J., Poole, C. D., & Gale, E. A. M. (2009) · Diabetologia
Metabolism, Diabetes, and CancerDiabetes Treatment and Management
Cited by 1,124
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Large-scale discovery of novel genetic causes of developmental disorders
Study, T. D. D. D. (2015) · Nature
Genomics and Rare DiseasesGenomic variations and chromosomal abnormalities
Cited by 1,124
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Insulin signaling in osteoblasts integrates bone remodeling and energy metabolism
Ferron, M., Wei, J., Yoshizawa, T., Del Fattore, A., DePinho, R. A., Teti, A., Ducy, P., & Karsenty, G. (2010) · Cell
Bone Metabolism and DiseasesBone health and osteoporosis research
Cited by 1,123
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