Most cited biochemistry, genetics and molecular biology papers
- Verified
Differential Function of the Prolyl Hydroxylases PHD1, PHD2, and PHD3 in the Regulation of Hypoxia-inducible Factor
Appelhoff, R. J., Tian, Y.-M., Raval, R. R., Turley, H., Harris, A. L., Pugh, C. W., Ratcliffe, P. J., & Gleadle, J. M. (2004) · Journal of Biological Chemistry
Cancer, Hypoxia, and MetabolismMetal-Catalyzed Oxygenation Mechanisms
Cited by 1,108
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Pooling across cells to normalize single-cell RNA sequencing data with many zero counts
L. Lun, A. T., Bach, K., & Marioni, J. C. (2016) · Genome Biology
Single-cell and spatial transcriptomicsGene expression and cancer classification
Cited by 1,108
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Lysosomal turnover, but not a cellular level, of endogenous LC3 is a marker for autophagy
Tanida, I., Minematsu-Ikeguchi, N., Ueno, T., & Kominami, E. (2005) · Autophagy
Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism
Cited by 1,108
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Multiple Rare Alleles Contribute to Low Plasma Levels of HDL Cholesterol
Cohen, J. C., Kiss, R. S., Pertsemlidis, A., Marcel, Y. L., McPherson, R., & Hobbs, H. H. (2004) · Science
Genetic Associations and EpidemiologyLipoproteins and Cardiovascular Health
Cited by 1,108
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Systems Biology and New Technologies Enable Predictive and Preventative Medicine
Hood, L., Heath, J. R., Phelps, M. E., & Lin, B. (2004) · Science
Bioinformatics and Genomic NetworksGene Regulatory Network Analysis
Cited by 1,108
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A high-resolution map of human evolutionary constraint using 29 mammals
Broad Institute Sequencing Platform and Whole Genome Assembly Team, Lindblad-Toh, K., Baylor College of Medicine Human Genome Sequencing Center Sequencing Team, Genome Institute at Washington University, Garber, M., Zuk, O., Lin, M. F., Parker, B. J., Washietl, S., Kheradpour, P., et al. (2011) · Nature
Genomics and Phylogenetic StudiesChromosomal and Genetic Variations
Cited by 1,108
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Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
Bouskra, D., Brézillon, C., Bérard, M., Werts, C., Varona, R., Boneca, I. G., & Eberl, G. (2008) · Nature
Gut microbiota and healthImmune Response and Inflammation
Cited by 1,107
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Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
Nisoli, E., Tonello, C., Cardile, A., Cozzi, V., Bracale, R., Tedesco, L., Falcone, S., Valerio, A., Cantoni, O., Clementi, E., et al. (2005) · Science
Genetics, Aging, and Longevity in Model OrganismsSirtuins and Resveratrol in Medicine
Cited by 1,107
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Targeting Free Radicals in Oxidative Stress-Related Human Diseases
Poprac, P., Jomova, K., Simunkova, M., Kollar, V., Rhodes, C. J., & Valko, M. (2017) · Trends in Pharmacological Sciences
Redox biology and oxidative stressAntioxidant Activity and Oxidative Stress
Cited by 1,107
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Monitoring and Measuring Autophagy
Yoshii, S. R., & Mizushima, N. (2017) · International Journal of Molecular Sciences
Autophagy in Disease and TherapyCalcium signaling and nucleotide metabolism
Cited by 1,107
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Pan-cancer whole-genome analyses of metastatic solid tumours
Priestley, P., Baber, J., Lolkema, M. P., Steeghs, N., de Bruijn, E., Shale, C., Duyvesteyn, K., Haidari, S., van Hoeck, A., Onstenk, W., et al. (2019) · Nature
Cancer Genomics and DiagnosticsChromatin Remodeling and Cancer
Cited by 1,106
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The Genetic Architecture of Quantitative Traits
Mackay, T. F. C. (2001) · Annual Review of Genetics
Genetic Mapping and Diversity in Plants and AnimalsGenetic and phenotypic traits in livestock
Cited by 1,106
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Skeletal muscle hypertrophy and atrophy signaling pathways
Glass, D. J. (2005) · The International Journal of Biochemistry & Cell Biology
Muscle Physiology and DisordersMuscle metabolism and nutrition
Cited by 1,106
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Dimerization, DNA Binding, and Transactivation Properties of Hypoxia-inducible Factor 1
Jiang, B.-H., Rue, E., Wang, G. L., Roe, R., & Semenza, G. L. (1996) · Journal of Biological Chemistry
Cancer, Hypoxia, and MetabolismErythropoietin and Anemia Treatment
Cited by 1,106
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Double indexing overcomes inaccuracies in multiplex sequencing on the Illumina platform
Kircher, M., Sawyer, S., & Meyer, M. (2012) · Nucleic Acids Research
Genomics and Phylogenetic StudiesGenomics and Rare Diseases
Cited by 1,106
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Oncogenic alterations of metabolism
Dang, C. V., & Semenza, G. L. (1999) · Trends in Biochemical Sciences
Cancer, Hypoxia, and MetabolismMetabolism, Diabetes, and Cancer
Cited by 1,106
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Safety and Anti-Inflammatory Activity of Curcumin: A Component of Tumeric ( Curcuma longa )
Chainani-Wu, N. (2003) · The Journal of Alternative and Complementary Medicine
Curcumin's Biomedical ApplicationsGinger and Zingiberaceae research
Cited by 1,106
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Oxidative damage to DNA during aging: 8-hydroxy-2'-deoxyguanosine in rat organ DNA and urine.
Fraga, C. G., Shigenaga, M. K., Park, J. W., Degan, P., & Ames, B. N. (1990) · Proceedings of the National Academy of Sciences
Genetics, Aging, and Longevity in Model OrganismsDNA Repair Mechanisms
Cited by 1,106
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Classical twin studies and beyond
Boomsma, D., Busjahn, A., & Peltonen, L. (2002) · Nature Reviews Genetics
Genetic Associations and EpidemiologyAssisted Reproductive Technology and Twin Pregnancy
Cited by 1,105
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Urolithin A induces mitophagy and prolongs lifespan in C. elegans and increases muscle function in rodents
Ryu, D., Mouchiroud, L., Andreux, P. A., Katsyuba, E., Moullan, N., Nicolet-dit-Félix, A. A., Williams, E. G., Jha, P., Lo Sasso, G., Huzard, D., et al. (2016) · Nature Medicine
Genetics, Aging, and Longevity in Model OrganismsPomegranate: compositions and health benefits
Cited by 1,105
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miRNPs: a novel class of ribonucleoproteins containing numerous microRNAs
Mourelatos, Z., Dostie, J., Paushkin, S., Sharma, A., Charroux, B., Abel, L., Rappsilber, J., Mann, M., & Dreyfuss, G. (2002) · Genes & Development
MicroRNA in disease regulationRNA Research and Splicing
Cited by 1,105
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Patients with familial adenomatous polyposis harbor colonic biofilms containing tumorigenic bacteria
Dejea, C. M., Fathi, P., Craig, J. M., Boleij, A., Taddese, R., Geis, A. L., Wu, X., DeStefano Shields, C. E., Hechenbleikner, E. M., Huso, D. L., et al. (2018) · Science
Gut microbiota and healthBacterial biofilms and quorum sensing
Cited by 1,105
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Thematic review series: Glycerolipids. DGAT enzymes and triacylglycerol biosynthesis
Yen, C.-L. E., Stone, S. J., Koliwad, S., Harris, C., & Farese, R. V. (2008) · Journal of Lipid Research
Lipid metabolism and biosynthesisLipid metabolism and disorders
Cited by 1,105
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An absolute requirement for Pax7-positive satellite cells in acute injury-induced skeletal muscle regeneration
Lepper, C., Partridge, T. A., & Fan, C.-M. (2011) · Development
Muscle Physiology and DisordersCongenital heart defects research
Cited by 1,105
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